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Seyedeh Somayyeh Mousavi

Publications and source records attributed to Seyedeh Somayyeh Mousavi.

4 recordsLinked to original sources

Leveraging Few-Shot Learning and Large Language Models for Analyzing Blood Pressure Variations Across Biological Sex from Scientific Literature

Current blood pressure (BP) technologies and standards were established decades ago, and these standards are still used worldwide today, often without adjusting BP readings for individual demographic factors such as sex and age. While these standards provide useful guidelines and help identify at-risk patients, they are not fully reliable for diagnosis due to the lack of demographic considerations. This study aims to assess the feasibility of using large language models (LLMs) for the automated extraction of BP-related information from the scientific literature, with a focus on biological sex-based distinctions in BP distributions. We employed natural language processing (NLP) methods to extract the means and standard deviations of BP values from the literature, distinguishing by biological sex. We developed a Solr-based search engine to retrieve scientific articles containing BP-related keywords and biological sex indicators from PubMed. From the retrieved articles, we created a manually reviewed subset comprising 213 articles including 90 cases that reported BP values based on biological sex. We experimented with one few-shot learning method and two zero-shot LLM-based methods---LLaMA3 and GPT-3.5---to extract the mean and standard deviations of BP values, and the associated biological sex. Based on the automatically-extracted information, we generated heatmaps and contour plots to study the variations of BP values across biological sex.

cs.CL↗

Learning from Two Decades of Blood Pressure Data: Demography-Specific Patterns Across 75 Million Patient Encounters

Hypertension is a global health concern with an increasing prevalence, underscoring the need for effective monitoring and analysis of blood pressure (BP) dynamics. We analyzed a substantial BP dataset comprising 75,636,128 records from 2,054,462 unique patients collected between 2000 and 2022 at Emory Healthcare in Georgia, USA, representing a demographically diverse population. We examined and compared population-wide statistics of bivariate changes in systolic BP (SBP) and diastolic BP (DBP) across sex, age, and race/ethnicity. The analysis revealed that males have higher BP levels than females and exhibit a distinct BP profile with age. Notably, average SBP consistently rises with age, whereas average DBP peaks in the forties age group. Among the ethnic groups studied, Blacks have marginally higher BPs and a greater standard deviation. We also discovered a significant correlation between SBP and DBP at the population level, a phenomenon not previously researched. These results emphasize the importance of demography-specific BP analysis for clinical diagnosis and provide valuable insights for developing personalized, demography-specific healthcare interventions.

q-bio.QM↗

A Survey on Blood Pressure Measurement Technologies: Addressing Potential Sources of Bias

Regular blood pressure (BP) monitoring in clinical and ambulatory settings plays a crucial role in the prevention, diagnosis, treatment, and management of cardiovascular diseases. Recently, the widespread adoption of ambulatory BP measurement devices has been driven predominantly by the increased prevalence of hypertension and its associated risks and clinical conditions. Recent guidelines advocate for regular BP monitoring as part of regular clinical visits or even at home. This increased utilization of BP measurement technologies has brought up significant concerns, regarding the accuracy of reported BP values across settings. In this survey, focusing mainly on cuff-based BP monitoring technologies, we highlight how BP measurements can demonstrate substantial biases and variances due to factors such as measurement and device errors, demographics, and body habitus. With these inherent biases, the development of a new generation of cuff-based BP devices which use artificial-intelligence (AI) has significant potential. We present future avenues where AI-assisted technologies can leverage the extensive clinical literature on BP-related studies together with the large collections of BP records available in electronic health records. These resources can be combined with machine learning approaches, including deep learning and Bayesian inference, to remove BP measurement biases and to provide individualized BP-related cardiovascular risk indexes.

physics.med-ph↗

ECG-Based Blood Pressure Estimation Using Mechano-Electric Coupling Concept

The Electrocardiograph signal represents the heart's electrical activity while blood pressure results from the heart's mechanical activity. Previous studies have investigated how the heart's electrical and mechanical activities are related and have referred to their relationship as the Mechano-Electric Coupling term. A new method to estimate the blood pressure including is proposed which uses only the Electrocardiograph signal. In spite of studies performed on feature extraction based on the signals' physiological parameters (Parameter-based), in this work, the feature vectors are formed with samples of the Electrocardiograph signal in a particular time frame (Whole-based) and these vectors are input into Adaptive Boosting Regression to estimate blood pressure. The nonlinear relationship which correlates blood pressure with the Electrocardiograph signal is concluded by the results of this study. According to the results, the used algorithms, for estimating both diastolic blood pressures and mean arterial pressure, are in compliance with the standards of the Association for the Advancement of Medical Instrumentation. Also, according to the British Hypertension Society standard, estimating diastolic blood pressures and mean arterial pressure with the proposed method attain an A grade while it achieves B for systolic blood pressure. The results indicate that using the introduced method, blood pressure can be estimated continuously, noninvasively, without cuff, calibration-free and by using only the Electrocardiograph signal.

eess.SP↗