Shaojie Hou | Searcharxiv

arXiv2025

CrowdAL: Towards a Blockchain-empowered Active Learning System in Crowd Data Labeling

Active Learning (AL) is a machine learning technique where the model selectively queries the most informative data points for labeling by human experts. Integrating AL with crowdsourcing leverages crowd diversity to enhance data labeling but introduces challenges in consensus and privacy. This poster presents CrowdAL, a blockchain-empowered crowd AL system designed to address these challenges. CrowdAL integrates blockchain for transparency and a tamper-proof incentive mechanism, using smart contracts to evaluate crowd workers' performance and aggregate labeling results, and employs zero-knowledge proofs to protect worker privacy.

cs.CR↗

arXiv2023

Enhancing Cell Proliferation and Migration by MIR-Carbonyl Vibrational Coupling: Insights from Transcriptome Profiling

Cell proliferation and migration highly relate to normal tissue self-healing, therefore it is highly significant for artificial controlling. Recently, vibrational strong coupling between biomolecules and Mid-infrared (MIR) light photons has been successfully used to modify in vitro bioreactions, neuronal signaling and even animal behavior. However, the synergistic effects from molecules to cells remains unclear, and the regulation of MIR on cells needs to be explained from the molecular level. Herein, the proliferation rate and migration capacity of fibroblasts were increased by 156% and 162.5%, respectively, by vibratory coupling of 5.6 micrometers photons with carbonyl groups in biomolecules. Through transcriptome sequencing analysis, the regulatory mechanism of infrared light in 5.6 micrometers was explained from the level of signal pathway and cell components. 5.6 micrometers optical high power lasers can regulate cell function through vibrational strong coupling while minimizing photothermal damage. This work not only sheds light on the non-thermal effect on MIR light-based on wound healing, but also provides new evidence to future frequency medicine.

q-bio.GN↗