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Shashidhara Marathe

Publications and source records attributed to Shashidhara Marathe.

4 recordsLinked to original sources

Spatial resolution of X-ray beam-tracking microscopy

X-ray beam-tracking is a phase-contrast imaging technique capable of simultaneously retrieving transmission, phase, and dark-field images. Although the spatial resolution in beam-tracking is largely considered to be 'aperture driven', no model yet exists to describe this in full. The dark-field channel is of particular interest, due to previous observations of anomalously high sharpness compared to transmission and phase channels. We derive a full optical transfer function model for each contrast channel using the Fokker-Planck equation for near-field imaging. Experimental validation using both synchrotron-based and laboratory-based setups, with 15 um circular and 10 um rectangular apertures, reveals a limiting resolution of at least 3 um, much smaller than the apertures themselves. Together, the model and the supporting experiments offer a full description of spatial resolution in beam-tracking, and formally confirm the greater spatial resolution in the dark-field channel. These findings open new possibilities in system design and experimental protocols to exploit these capabilities.

physics.optics

Retrieval of multiple fibre orientations using X-ray dark-field signal modelling

Dark-field imaging is widely used to infer fibre orientation from signal modulation as a function of sample orientation. However, current X-ray dark-field retrieval methods are restricted to single orientations and require tomography to resolve overlapping structures. This approach is time-consuming and not suitable for thin materials, which are common in materials science. Here we present a dark-field model capable of retrieving multiple fibre orientations within a single pixel. The model, based on a geometrical description of fibre scattering, was validated through Monte Carlo simulations and experiments using beam-tracking setups with 1D and 2D masks. Results demonstrate reliable orientation retrieval for up to two fibres per pixel, with the 2D mask providing multi-directional sensitivity in a single acquisition and enabling faster and simplified data collection.

physics.med-ph

Three-Dimensional, Multimodal Synchrotron Data for Machine Learning Applications

Machine learning techniques are being increasingly applied in medical and physical sciences across a variety of imaging modalities; however, an important issue when developing these tools is the availability of good quality training data. Here we present a unique, multimodal synchrotron dataset of a bespoke zinc-doped Zeolite 13X sample that can be used to develop advanced deep learning and data fusion pipelines. Multi-resolution micro X-ray computed tomography was performed on a zinc-doped Zeolite 13X fragment to characterise its pores and features, before spatially resolved X-ray diffraction computed tomography was carried out to characterise the homogeneous distribution of sodium and zinc phases. Zinc absorption was controlled to create a simple, spatially isolated, two-phase material. Both raw and processed data is available as a series of Zenodo entries. Altogether we present a spatially resolved, three-dimensional, multimodal, multi-resolution dataset that can be used for the development of machine learning techniques. Such techniques include development of super-resolution, multimodal data fusion, and 3D reconstruction algorithm development.

cs.LG

High angular sensitivity X-ray phase-contrast microtomography of soft-tissue through a two-directional beam-tracking synchrotron set-up

Two-directional beam-tracking (2DBT) is a method for phase-contrast imaging and tomography that uses an intensity modulator to structure the X-ray beam into an array of independent circular beamlets that are resolved by a high-resolution detector. It features isotropic spatial resolution, provides two-dimensional phase sensitivity, and enables the three-dimensional reconstructions of the refractive index decrement, $δ$, and the attenuation coefficient, $μ$. In this work, we report on the angular sensitivity and the spatial resolution of 2DBT images in a synchrotron-based implementation. In its best configuration, we obtained angular sensitivities of $\sim$20 $n$rad and spatial resolution of at least 6.25 $μ$m in phase-contrast images. We also demonstrate exemplar application to the three-dimensional imaging of soft tissue samples, including a mouse liver and a decellularised porcine dermis.

physics.ins-det