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Shaun Truelove

Publications and source records attributed to Shaun Truelove.

3 recordsLinked to original sources

IDOBE: Infectious Disease Outbreak forecasting Benchmark Ecosystem

Epidemic forecasting has become an integral part of real-time infectious disease outbreak response. While collaborative ensembles composed of statistical and machine learning models have become the norm for real-time forecasting, standardized benchmark datasets for evaluating such methods are lacking. Further, there is limited understanding on performance of these methods for novel outbreaks with limited historical data. In this paper, we propose IDOBE, a curated collection of epidemiological time series focused on outbreak forecasting. IDOBE compiles from multiple data repositories spanning over a century of surveillance and across U.S. states and global locations. We perform derivative-based segmentation to generate over 10,000 outbreaks covering multiple outcomes such as cases and hospitalizations for 13 diseases. We consider a variety of information-theoretic and distributional measures to quantify the epidemiological diversity of the dataset. Finally, we perform multi-horizon short-term forecasting (1- to 4-week-ahead) through the progression of the outbreak using 11 baseline models and report on their performance. In addition to standard metrics such as NMSE and MAPE for point forecasts, we include probabilistic scoring rules such as Normalized Weighted Interval Score (NWIS) to quantify the performance. We find that MLP-based methods have the most robust performance, with statistical methods having a slight edge during the pre-peak phase. IDOBE dataset along with baselines are released publicly on https://github.com/NSSAC/IDOBE to enable standardized, reproducible benchmarking of outbreak forecasting methods.

cs.LG

Chimeric Forecasting: Blending Human Judgment and Computational Methods for Improved, Real-time Forecasts of Influenza Hospitalizations

Infectious disease forecasts can reduce mortality and morbidity by supporting evidence-based public health decision making. Most epidemic models train on surveillance and structured data (e.g. weather, mobility, media), missing contextual information about the epidemic. Human judgment forecasts are novel data, asking humans to generate forecasts based on surveillance data and contextual information. Our primary hypothesis is that an epidemic model trained on surveillance plus human judgment forecasts (a chimeric model) can produce more accurate long-term forecasts of incident hospitalizations compared to a control model trained only on surveillance. Humans have a finite amount of cognitive energy to forecast, limiting them to forecast a small number of states. Our secondary hypothesis is that a model can map human judgment forecasts from a small number of states to all states with similar performance. For the 2023/24 season, we collected weekly incident influenza hospitalizations for all US states, and 696 human judgment forecasts of peak epidemic week and the maximum number of hospitalizations (peak intensity) for ten of the most populous states. We found a chimeric model outperformed a control model on long-term forecasts. Compared to human judgment, a chimeric model produced forecasts of peak epidemic week and peak intensity with similar or improved performance. Forecasts of peak epidemic week and peak intensity for the ten states where humans input forecasts vs a model that extended these forecasts to all states showed similar performance to one another. Our results suggest human judgment forecasts are a viable data source that can improve infectious disease forecasts and support public health decisions.

stat.AP

Infectious disease surveillance needs for the United States: lessons from COVID-19

The COVID-19 pandemic has highlighted the need to upgrade systems for infectious disease surveillance and forecasting and modeling of the spread of infection, both of which inform evidence-based public health guidance and policies. Here, we discuss requirements for an effective surveillance system to support decision making during a pandemic, drawing on the lessons of COVID-19 in the U.S., while looking to jurisdictions in the U.S. and beyond to learn lessons about the value of specific data types. In this report, we define the range of decisions for which surveillance data are required, the data elements needed to inform these decisions and to calibrate inputs and outputs of transmission-dynamic models, and the types of data needed to inform decisions by state, territorial, local, and tribal health authorities. We define actions needed to ensure that such data will be available and consider the contribution of such efforts to improving health equity.

cs.CY