arXiv subjects

Shenbing Kuang

Publications and source records attributed to Shenbing Kuang.

3 recordsLinked to original sources

arXiv2007

Thermal Impact on Spiking Properties in Hodgkin-Huxley Neuron with Synaptic Stimulus

The effect of environmental temperature on neuronal spiking behaviors is investigated by numerically simulating the temperature dependence of spiking threshold of the Hodgkin-Huxley neuron subject to synaptic stimulus. We find that the spiking threshold exhibits a global minimum in a "comfortable temperature" range where spike initiation needs weakest synaptic strength, indicating the occurrence of optimal use of synaptic transmission in neural system. We further explore the biophysical origin of this phenomenon in ion channel gating kinetics and also discuss its possible biological relevance in information processing in neural systems.

q-bio.NC↗

arXiv2007

Theoretical Analysis of Subthreshold Oscillatory Behaviors in Nonlinear Autonomous Systems

We have developed a linearization method to investigate the subthreshold oscillatory behaviors in nonlinear autonomous systems. By considering firstly the neuronal system as an example, we show that this theoretical approach can predict quantitatively the subthreshold oscillatory activities, including the damping coefficients and the oscillatory frequencies which are in good agreement with those observed in experiments. Then we generalize the linearization method to an arbitrary autonomous nonlinear system. The detailed extension of this theoretical approach is also presented and further discussed.

q-bio.QM↗

arXiv2007

Influence of Temperature on Neuronal Excitability in Cochlear Nucleus

The influence of temperature on neuronal excitability is studied by numerical simulations on the spiking threshold characteristics of bushy cells in cochlear nucleus periodically stimulated by synaptic currents. The results reveal that there is a cut-off frequency for the spiking of bushy cell in a specific temperature environment, corresponding to the existence of a critical temperature for the neuron to respond with real spikes to the synaptic stimulus of a given frequency, due to the finiteness of spike width. An optimal temperature range for neuronal spiking is also found for a specific stimulus frequency, and the temperature range span decreases with increasing stimulus frequency. These findings imply that there is a physiological temperature range which is beneficial for the information processing in auditory system.

q-bio.NC↗