arXiv subjects

Sheng Wang

Publications and source records attributed to Sheng Wang.

At least 109 records · Page 6Linked to original sources

arXiv2025

Med-LEGO: Editing and Adapting toward Generalist Medical Image Diagnosis

The adoption of visual foundation models has become a common practice in computer-aided diagnosis (CAD). While these foundation models provide a viable solution for creating generalist medical AI, privacy concerns make it difficult to pre-train or continuously update such models across multiple domains and datasets, leading many studies to focus on specialist models. To address this challenge, we propose Med-LEGO, a training-free framework that enables the seamless integration or updating of a generalist CAD model by combining multiple specialist models, similar to assembling LEGO bricks. Med-LEGO enhances LoRA (low-rank adaptation) by incorporating singular value decomposition (SVD) to efficiently capture the domain expertise of each specialist model with minimal additional parameters. By combining these adapted weights through simple operations, Med-LEGO allows for the easy integration or modification of specific diagnostic capabilities without the need for original data or retraining. Finally, the combined model can be further adapted to new diagnostic tasks, making it a versatile generalist model. Our extensive experiments demonstrate that Med-LEGO outperforms existing methods in both cross-domain and in-domain medical tasks while using only 0.18% of full model parameters. These merged models show better convergence and generalization to new tasks, providing an effective path toward generalist medical AI.

cs.CV↗

arXiv2025

TreeSynth: Synthesizing Diverse Data from Scratch via Tree-Guided Subspace Partitioning

Model customization necessitates high-quality and diverse datasets, but acquiring such data remains time-consuming and labor-intensive. Despite the great potential of large language models (LLMs) for data synthesis, current approaches are constrained by limited seed data, model biases, and low-variation prompts, resulting in limited diversity and biased distributions with the increase of data scales. To tackle this challenge, we introduce TREESYNTH, a tree-guided subspace-based data synthesis approach inspired by decision trees. It constructs a spatial partitioning tree to recursively divide a task-specific full data space (i.e., root node) into numerous atomic subspaces (i.e., leaf nodes) with mutually exclusive and exhaustive attributes to ensure both distinctiveness and comprehensiveness before synthesizing samples within each atomic subspace. This globally dividing-and-synthesizing method finally collects subspace samples into a comprehensive dataset, effectively circumventing repetition and space collapse to ensure the diversity of large-scale data synthesis. Furthermore, the spatial partitioning tree enables sample allocation into atomic subspaces, allowing the rebalancing of existing datasets for more balanced and comprehensive distributions. Empirically, extensive experiments across diverse benchmarks consistently demonstrate the superior data diversity, model performance, and robust scalability of TREESYNTH compared to both human-crafted datasets and peer data synthesis methods, with an average performance gain reaching 10%. Besides, the consistent improvements of TREESYNTH-balanced datasets highlight its efficacious application to redistribute existing datasets for more comprehensive coverage and the induced performance enhancement. The code is available at https://github.com/cpa2001/TreeSynth.

cs.LG↗

arXiv2025

Cartan's Path Development, the Logarithmic Signature and a Conjecture of Lyons-Sidorova

The signature transform, which is defined in terms of iterated path integrals of all orders, provides a faithful representation of the group of tree-reduced geometric rough paths. While the signature coefficients are known to decay factorially fast, the coefficients of the logarithimic signature generically only possess geometric decay. It was conjectured by T. Lyons and N. Sidorova that the only tree-reduced paths with bounded variation (BV) whose logarithmic signature can have infinite radius of convergence are straight lines. This conjecture was confirmed in the same work for certain types of paths and the general BV case remains unsolved. The aim of the present article is to develop a deeper understanding towards the Lyons-Sidorova conjecture. We prove that, if the logarithmic signature has infinite radius of convergence, the signature coefficients must satisfy an infinite system of rigid algebraic identities defined in terms of iterated integrals along complex exponential one-forms. These iterated integral identities impose strong geometric constraints on the underlying path, and in some special situations, confirm the conjecture. As a non-trivial application of our integral identities, we prove a strengthened version of the conjecture, which asserts that if the logarithmic signature of a BV path has infinite radius of convergence over all sub-intervals of time, the underlying path must be a straight line. Our methodology relies on Cartan's path development onto the complex semisimple Lie algebras $\mathfrak{sl}_m(\mathbb{C})$. The special root patterns of $\mathfrak{sl}_m(\mathbb{C})$ allow one to project the infinite-dimensional Baker-Campbell-Hausdorff (BCH) formula in a very special finite dimensional manner to yield meaningful quantitative relations between BCH-type singularities and the vanishing of certain iterated path integrals.

math.PR↗

arXiv2025

Dynamic allocation: extremes, tail dependence, and regime Shifts

By capturing outliers, volatility clustering, and tail dependence in the asset return distribution, we build a sophisticated model to predict the downside risk of the global financial market. We further develop a dynamic regime switching model that can forecast real-time risk regime of the market. Our GARCH-DCC-Copula risk model can significantly improve both risk- and alpha-based global tactical asset allocation strategies. Our risk regime has strong predictive power of quantitative equity factor performance, which can help equity investors to build better factor models and asset allocation managers to construct more efficient risk premia portfolios.

econ.EM↗

arXiv2025

FedAPM: Federated Learning via ADMM with Partial Model Personalization

In federated learning (FL), the assumption that datasets from different devices are independent and identically distributed (i.i.d.) often does not hold due to user differences, and the presence of various data modalities across clients makes using a single model impractical. Personalizing certain parts of the model can effectively address these issues by allowing those parts to differ across clients, while the remaining parts serve as a shared model. However, we found that partial model personalization may exacerbate client drift (each client's local model diverges from the shared model), thereby reducing the effectiveness and efficiency of FL algorithms. We propose an FL framework based on the alternating direction method of multipliers (ADMM), referred to as FedAPM, to mitigate client drift. We construct the augmented Lagrangian function by incorporating first-order and second-order proximal terms into the objective, with the second-order term providing fixed correction and the first-order term offering compensatory correction between the local and shared models. Our analysis demonstrates that FedAPM, by using explicit estimates of the Lagrange multiplier, is more stable and efficient in terms of convergence compared to other FL frameworks. We establish the global convergence of FedAPM training from arbitrary initial points to a stationary point, achieving three types of rates: constant, linear, and sublinear, under mild assumptions. We conduct experiments using four heterogeneous and multimodal datasets with different metrics to validate the performance of FedAPM. Specifically, FedAPM achieves faster and more accurate convergence, outperforming the SOTA methods with average improvements of 12.3% in test accuracy, 16.4% in F1 score, and 18.0% in AUC while requiring fewer communication rounds.

cs.LG↗

arXiv2025

MMedPO: Aligning Medical Vision-Language Models with Clinical-Aware Multimodal Preference Optimization

The advancement of Large Vision-Language Models (LVLMs) has propelled their application in the medical field. However, Medical LVLMs (Med-LVLMs) encounter factuality challenges due to modality misalignment, where the models prioritize textual knowledge over visual input, leading to hallucinations that contradict information in medical images. Previous attempts to enhance modality alignment in Med-LVLMs through preference optimization have inadequately mitigated clinical relevance in preference data, making these samples easily distinguishable and reducing alignment effectiveness. To address this challenge, we propose MMedPO, a novel multimodal medical preference optimization approach that considers the clinical relevance of preference samples to enhance Med-LVLM alignment. MMedPO curates multimodal preference data by introducing two types of dispreference: (1) plausible hallucinations injected through target Med-LVLMs or GPT-4o to produce medically inaccurate responses, and (2) lesion region neglect achieved through local lesion-noising, disrupting visual understanding of critical areas. We then calculate clinical relevance for each sample based on scores from multiple Med-LLMs and visual tools, and integrate these scores into the preference optimization process as weights, enabling effective alignment. Our experiments demonstrate that MMedPO significantly enhances factual accuracy in Med-LVLMs, achieving substantial improvements over existing preference optimization methods by averaging 14.2% and 51.7% across the Med-VQA and report generation tasks. Our code are available in https://github.com/aiming-lab/MMedPO.

cs.CV↗

arXiv2025

ReactDiff: Latent Diffusion for Facial Reaction Generation

Given the audio-visual clip of the speaker, facial reaction generation aims to predict the listener's facial reactions. The challenge lies in capturing the relevance between video and audio while balancing appropriateness, realism, and diversity. While prior works have mostly focused on uni-modal inputs or simplified reaction mappings, recent approaches such as PerFRDiff have explored multi-modal inputs and the one-to-many nature of appropriate reaction mappings. In this work, we propose the Facial Reaction Diffusion (ReactDiff) framework that uniquely integrates a Multi-Modality Transformer with conditional diffusion in the latent space for enhanced reaction generation. Unlike existing methods, ReactDiff leverages intra- and inter-class attention for fine-grained multi-modal interaction, while the latent diffusion process between the encoder and decoder enables diverse yet contextually appropriate outputs. Experimental results demonstrate that ReactDiff significantly outperforms existing approaches, achieving a facial reaction correlation of 0.26 and diversity score of 0.094 while maintaining competitive realism. The code is open-sourced at \href{https://github.com/Hunan-Tiger/ReactDiff}{github}.

cs.CV↗

arXiv2025

MlingConf: A Comprehensive Study of Multilingual Confidence Estimation on Large Language Models

The tendency of Large Language Models (LLMs) to generate hallucinations raises concerns regarding their reliability. Therefore, confidence estimations indicating the extent of trustworthiness of the generations become essential. However, current LLM confidence estimations in languages other than English remain underexplored. This paper addresses this gap by introducing a comprehensive investigation of Multilingual Confidence estimation (MlingConf) on LLMs, focusing on both language-agnostic (LA) and language-specific (LS) tasks to explore the performance and language dominance effects of multilingual confidence estimations on different tasks. The benchmark comprises four meticulously checked and human-evaluated high-quality multilingual datasets for LA tasks and one for the LS task tailored to specific social, cultural, and geographical contexts of a language. Our experiments reveal that on LA tasks English exhibits notable linguistic dominance in confidence estimations than other languages, while on LS tasks, using question-related language to prompt LLMs demonstrates better linguistic dominance in multilingual confidence estimations. The phenomena inspire a simple yet effective native-tone prompting strategy by employing language-specific prompts for LS tasks, effectively improving LLMs' reliability and accuracy in LS scenarios.

cs.CL↗

arXiv2025

UAlign: Leveraging Uncertainty Estimations for Factuality Alignment on Large Language Models

Despite demonstrating impressive capabilities, Large Language Models (LLMs) still often struggle to accurately express the factual knowledge they possess, especially in cases where the LLMs' knowledge boundaries are ambiguous. To improve LLMs' factual expressions, we propose the UAlign framework, which leverages Uncertainty estimations to represent knowledge boundaries, and then explicitly incorporates these representations as input features into prompts for LLMs to Align with factual knowledge. First, we prepare the dataset on knowledge question-answering (QA) samples by calculating two uncertainty estimations, including confidence score and semantic entropy, to represent the knowledge boundaries for LLMs. Subsequently, using the prepared dataset, we train a reward model that incorporates uncertainty estimations and then employ the Proximal Policy Optimization (PPO) algorithm for factuality alignment on LLMs. Experimental results indicate that, by integrating uncertainty representations in LLM alignment, the proposed UAlign can significantly enhance the LLMs' capacities to confidently answer known questions and refuse unknown questions on both in-domain and out-of-domain tasks, showing reliability improvements and good generalizability over various prompt- and training-based baselines.

cs.CL↗

arXiv2025

Strong Coupling Expansion of Gluodynamics on a Lattice under Rotation

The analytic strong coupling expansion of the gluodynamics under a rotation with an angular velocity $ω$ is reported. While the expansion is systematic, free from additional assumptions, the deconfinement temperature determined by the onset of the Polyakov loop expectation value decreases with the angular velocity up to $ω^2$, opposite to the tendency found in numerical simulations. As a by-product, a simple formula is obtained for the $ω^2$ coefficient of the deconfinement temperature shift in terms of the latent heat and the discontinuity of the moment of inertia at the transition without rotation. This formula is independent of the strong coupling and may benefit further investigation of the subject.

hep-ph↗

arXiv2025

HAMF: A Hybrid Attention-Mamba Framework for Joint Scene Context Understanding and Future Motion Representation Learning

Motion forecasting represents a critical challenge in autonomous driving systems, requiring accurate prediction of surrounding agents' future trajectories. While existing approaches predict future motion states with the extracted scene context feature from historical agent trajectories and road layouts, they suffer from the information degradation during the scene feature encoding. To address the limitation, we propose HAMF, a novel motion forecasting framework that learns future motion representations with the scene context encoding jointly, to coherently combine the scene understanding and future motion state prediction. We first embed the observed agent states and map information into 1D token sequences, together with the target multi-modal future motion features as a set of learnable tokens. Then we design a unified Attention-based encoder, which synergistically combines self-attention and cross-attention mechanisms to model the scene context information and aggregate future motion features jointly. Complementing the encoder, we implement the Mamba module in the decoding stage to further preserve the consistency and correlations among the learned future motion representations, to generate the accurate and diverse final trajectories. Extensive experiments on Argoverse 2 benchmark demonstrate that our hybrid Attention-Mamba model achieves state-of-the-art motion forecasting performance with the simple and lightweight architecture.

cs.CV↗

arXiv2025

Hotspot-Driven Peptide Design via Multi-Fragment Autoregressive Extension

Peptides, short chains of amino acids, interact with target proteins, making them a unique class of protein-based therapeutics for treating human diseases. Recently, deep generative models have shown great promise in peptide generation. However, several challenges remain in designing effective peptide binders. First, not all residues contribute equally to peptide-target interactions. Second, the generated peptides must adopt valid geometries due to the constraints of peptide bonds. Third, realistic tasks for peptide drug development are still lacking. To address these challenges, we introduce PepHAR, a hot-spot-driven autoregressive generative model for designing peptides targeting specific proteins. Building on the observation that certain hot spot residues have higher interaction potentials, we first use an energy-based density model to fit and sample these key residues. Next, to ensure proper peptide geometry, we autoregressively extend peptide fragments by estimating dihedral angles between residue frames. Finally, we apply an optimization process to iteratively refine fragment assembly, ensuring correct peptide structures. By combining hot spot sampling with fragment-based extension, our approach enables de novo peptide design tailored to a target protein and allows the incorporation of key hot spot residues into peptide scaffolds. Extensive experiments, including peptide design and peptide scaffold generation, demonstrate the strong potential of PepHAR in computational peptide binder design. Source code will be available at https://github.com/Ced3-han/PepHAR.

q-bio.BM↗

arXiv2025

UniCAD: Efficient and Extendable Architecture for Multi-Task Computer-Aided Diagnosis System

The growing complexity and scale of visual model pre-training have made developing and deploying multi-task computer-aided diagnosis (CAD) systems increasingly challenging and resource-intensive. Furthermore, the medical imaging community lacks an open-source CAD platform to enable the rapid creation of efficient and extendable diagnostic models. To address these issues, we propose UniCAD, a unified architecture that leverages the robust capabilities of pre-trained vision foundation models to seamlessly handle both 2D and 3D medical images while requiring only minimal task-specific parameters. UniCAD introduces two key innovations: (1) Efficiency: A low-rank adaptation strategy is employed to adapt a pre-trained visual model to the medical image domain, achieving performance on par with fully fine-tuned counterparts while introducing only 0.17% trainable parameters. (2) Plug-and-Play: A modular architecture that combines a frozen foundation model with multiple plug-and-play experts, enabling diverse tasks and seamless functionality expansion. Building on this unified CAD architecture, we establish an open-source platform where researchers can share and access lightweight CAD experts, fostering a more equitable and efficient research ecosystem. Comprehensive experiments across 12 diverse medical datasets demonstrate that UniCAD consistently outperforms existing methods in both accuracy and deployment efficiency. The source code and project page are available at https://mii-laboratory.github.io/UniCAD/.

cs.CV↗

arXiv2025

Budgeted Spatial Data Acquisition: When Coverage and Connectivity Matter

Data is undoubtedly becoming a commodity like oil, land, and labor in the 21st century. Although there have been many successful marketplaces for data trading, the existing data marketplaces lack consideration of the case where buyers want to acquire a collection of datasets (instead of one), and the overall spatial coverage and connectivity matter. In this paper, we take the first attempt to formulate this problem as Budgeted Maximum Coverage with Connectivity Constraint (BMCC), which aims to acquire a dataset collection with the maximum spatial coverage under a limited budget while maintaining spatial connectivity. To solve the problem, we propose two approximate algorithms with detailed theoretical guarantees and time complexity analysis, followed by two acceleration strategies to further improve the efficiency of the algorithm. Experiments are conducted on five real-world spatial dataset collections to verify the efficiency and effectiveness of our algorithms.

cs.DB↗

arXiv2025

D-LoRa: a Distributed Parameter Adaptation Scheme for LoRa Network

The deployment of LoRa networks necessitates joint performance optimization, including packet delivery rate, energy efficiency, and throughput. Additionally, multiple LoRa parameters for packet transmission must be dynamically configured to tailor the performance metrics prioritization across varying channel environments. Because of the coupling relationship between LoRa parameters and metrics, existing works have opted to focus on certain parameters or specific metrics to circumvent the intricate coupling relationship, leading to limited adaptability. Therefore, we propose D-LoRa, a distributed parameter adaptation scheme, based on reinforcement learning towards network performance. We decompose the joint performance optimization problem into multiple independent Multi-Armed Bandit (MAB) problems with different reward functions. We have also built a comprehensive analytical model for the LoRa network that considers path loss, quasi-orthogonality of spreading factor, and packet collision. Experimental results show that our scheme can increase packet delivery rate by up to 28.8% and demonstrates superior adaptability across different performance metrics.

cs.NI↗

arXiv2025

CLIP in Medical Imaging: A Survey

Contrastive Language-Image Pre-training (CLIP), a simple yet effective pre-training paradigm, successfully introduces text supervision to vision models. It has shown promising results across various tasks due to its generalizability and interpretability. The use of CLIP has recently gained increasing interest in the medical imaging domain, serving as a pre-training paradigm for image-text alignment, or a critical component in diverse clinical tasks. With the aim of facilitating a deeper understanding of this promising direction, this survey offers an in-depth exploration of the CLIP within the domain of medical imaging, regarding both refined CLIP pre-training and CLIP-driven applications. In this paper, we (1) first start with a brief introduction to the fundamentals of CLIP methodology; (2) then investigate the adaptation of CLIP pre-training in the medical imaging domain, focusing on how to optimize CLIP given characteristics of medical images and reports; (3) further explore practical utilization of CLIP pre-trained models in various tasks, including classification, dense prediction, and cross-modal tasks; and (4) finally discuss existing limitations of CLIP in the context of medical imaging, and propose forward-looking directions to address the demands of medical imaging domain. Studies featuring technical and practical value are both investigated. We expect this survey will provide researchers with a holistic understanding of the CLIP paradigm and its potential implications. The project page of this survey can also be found on https://github.com/zhaozh10/Awesome-CLIP-in-Medical-Imaging.

cs.CV↗

arXiv2025

RoboFlamingo-Plus: Fusion of Depth and RGB Perception with Vision-Language Models for Enhanced Robotic Manipulation

As robotic technologies advancing towards more complex multimodal interactions and manipulation tasks, the integration of advanced Vision-Language Models (VLMs) has become a key driver in the field. Despite progress with current methods, challenges persist in fusing depth and RGB information within 3D environments and executing tasks guided by linguistic instructions. In response to these challenges, we have enhanced the existing RoboFlamingo framework by introducing RoboFlamingo-Plus, which incorporates depth data into VLMs to significantly improve robotic manipulation performance. Our research achieves a nuanced fusion of RGB and depth information by integrating a pre-trained Vision Transformer (ViT) with a resampling technique, closely aligning this combined data with linguistic cues for superior multimodal understanding. The novelty of RoboFlamingo-Plus lies in its adaptation of inputs for depth data processing, leveraging a pre-trained resampler for depth feature extraction, and employing cross-attention mechanisms for optimal feature integration. These improvements allow RoboFlamingo-Plus to not only deeply understand 3D environments but also easily perform complex, language-guided tasks in challenging settings. Experimental results show that RoboFlamingo-Plus boosts robotic manipulation by 10-20% over current methods, marking a significant advancement. Codes and model weights are public at RoboFlamingo-Plus.

cs.RO↗

arXiv2025

A method for reversing the laser modulation in a Storage ring

The pursuit of coherent radiation generation remains a key direction in the advancement of storage ring light sources. Despite the potential of laser modulation in achieving this goal, it leads to a significant decline in the quality of the electron beam. Efforts to mitigate this decline have resulted in the proposal of demodulation schemes. However, implementing modulation and demodulation within the storage ring presents significant challenges due to dynamical and spatial constraints within straight sections. In this study, we propose a straightforward and easily implementable method for achieving reversible laser modulation in a storage ring. Notably, our approach circumvents the need for special storage ring requirements, such as lengthy straight sections or bypass section. Simulation results demonstrate a substantial restoration of beam quality following demodulation. This innovative scheme holds great promise for the realization of high repetition rate coherent storage ring light sources.

physics.acc-ph↗