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Sheng Zhang

Publications and source records attributed to Sheng Zhang.

At least 73 records · Page 4Linked to original sources

Generative Medical Event Models Improve with Scale

Realizing personalized medicine at scale calls for methods that distill insights from longitudinal patient journeys, which can be viewed as a sequence of medical events. Foundation models pretrained on large-scale medical event data represent a promising direction for scaling real-world evidence generation and generalizing to diverse downstream tasks. Using Epic Cosmos, a dataset with medical events from de-identified longitudinal health records for 16.3 billion encounters over 300 million unique patient records from 310 health systems, we introduce the Curiosity models, a family of decoder-only transformer models pretrained on 118 million patients representing 115 billion discrete medical events (151 billion tokens). We present the largest scaling-law study of medical event data, establishing a methodology for pretraining and revealing power-law scaling relationships for compute, tokens, and model size. Consequently, we pretrained a series of compute-optimal models with up to 1 billion parameters. Conditioned on a patient's real-world history, Curiosity autoregressively predicts the next medical event to simulate patient health timelines. We studied 78 real-world tasks, including diagnosis prediction, disease prognosis, and healthcare operations. Remarkably for a foundation model with generic pretraining and simulation-based inference, Curiosity generally outperformed or matched task-specific supervised models on these tasks, without requiring task-specific fine-tuning or few-shot examples. Curiosity's predictive power consistently improves as the model and pretraining scale. Our results show that Curiosity, a generative medical event foundation model, can effectively capture complex clinical dynamics, providing an extensible and generalizable framework to support clinical decision-making, streamline healthcare operations, and improve patient outcomes.

cs.LG↗

BoRe-Depth: Self-supervised Monocular Depth Estimation with Boundary Refinement for Embedded Systems

Depth estimation is one of the key technologies for realizing 3D perception in unmanned systems. Monocular depth estimation has been widely researched because of its low-cost advantage, but the existing methods face the challenges of poor depth estimation performance and blurred object boundaries on embedded systems. In this paper, we propose a novel monocular depth estimation model, BoRe-Depth, which contains only 8.7M parameters. It can accurately estimate depth maps on embedded systems and significantly improves boundary quality. Firstly, we design an Enhanced Feature Adaptive Fusion Module (EFAF) which adaptively fuses depth features to enhance boundary detail representation. Secondly, we integrate semantic knowledge into the encoder to improve the object recognition and boundary perception capabilities. Finally, BoRe-Depth is deployed on NVIDIA Jetson Orin, and runs efficiently at 50.7 FPS. We demonstrate that the proposed model significantly outperforms previous lightweight models on multiple challenging datasets, and we provide detailed ablation studies for the proposed methods. The code is available at https://github.com/liangxiansheng093/BoRe-Depth.

cs.CV↗

RECALL: REpresentation-aligned Catastrophic-forgetting ALLeviation via Hierarchical Model Merging

We unveil that internal representations in large language models (LLMs) serve as reliable proxies of learned knowledge, and propose RECALL, a novel representation-aware model merging framework for continual learning without access to historical data. RECALL computes inter-model similarity from layer-wise hidden representations over clustered typical samples, and performs adaptive, hierarchical parameter fusion to align knowledge across models. This design enables the preservation of domain-general features in shallow layers while allowing task-specific adaptation in deeper layers. Unlike prior methods that require task labels or incur performance trade-offs, RECALL achieves seamless multi-domain integration and strong resistance to catastrophic forgetting. Extensive experiments across five NLP tasks and multiple continual learning scenarios show that RECALL outperforms baselines in both knowledge retention and generalization, providing a scalable and data-free solution for evolving LLMs.

cs.CL↗

Embedding in Recommender Systems: A Survey

Recommender systems have become an essential component of many online platforms, providing personalized recommendations to users. A crucial aspect is embedding techniques that convert the high-dimensional discrete features, such as user and item IDs, into low-dimensional continuous vectors, which can enhance the recommendation performance. Embedding techniques have revolutionized the capture of complex entity relationships, generating significant research interest. This survey presents a comprehensive analysis of recent advances in recommender system embedding techniques. We examine centralized embedding approaches across matrix, sequential, and graph structures. In matrix-based scenarios, collaborative filtering generates embeddings that effectively model user-item preferences, particularly in sparse data environments. For sequential data, we explore various approaches including recurrent neural networks and self-supervised methods such as contrastive and generative learning. In graph-structured contexts, we analyze techniques like node2vec that leverage network relationships, along with applicable self-supervised methods. Our survey addresses critical scalability challenges in embedding methods and explores innovative directions in recommender systems. We introduce emerging approaches, including AutoML, hashing techniques, and quantization methods, to enhance performance while reducing computational complexity. Additionally, we examine the promising role of Large Language Models (LLMs) in embedding enhancement. Through detailed discussion of various architectures and methodologies, this survey aims to provide a thorough overview of state-of-the-art embedding techniques in recommender systems, while highlighting key challenges and future research directions.

cs.IR↗

Inverse designed Hamiltonians for perfect state transfer and remote entanglement generation, and applications in superconducting qubits

Hamiltonian inverse engineering enables the design of protocols for specific quantum evolutions or target state preparation. Perfect state transfer (PST) and remote entanglement generation are notable examples, as they serve as key primitives in quantum information processing. However, Hamiltonians obtained through conventional methods often lack robustness against noise. Assisted by inverse engineering, we begin with a noise-resilient energy spectrum and construct a class of Hamiltonians, referred to as the dome model, that significantly improves the system's robustness against noise, as confirmed by numerical simulations. This model introduces a tunable parameter $m$ that modifies the energy-level spacing and gives rise to a well-structured Hamiltonian. It reduces to the conventional PST model at $m=0$ and simplifies to a SWAP model involving only two end qubits in the large-$m$ regime. To address the challenge of scalability, we propose a cascaded strategy that divides long-distance PST into multiple consecutive PST steps. Our work is particularly suited for demonstration on superconducting qubits with tunable couplers, which enable rapid and flexible Hamiltonian engineering, thereby advancing the experimental potential of robust and scalable quantum information processing.

quant-ph↗

Use of Retrieval-Augmented Large Language Model Agent for Long-Form COVID-19 Fact-Checking

The COVID-19 infodemic calls for scalable fact-checking solutions that handle long-form misinformation with accuracy and reliability. This study presents SAFE (system for accurate fact extraction and evaluation), an agent system that combines large language models with retrieval-augmented generation (RAG) to improve automated fact-checking of long-form COVID-19 misinformation. SAFE includes two agents - one for claim extraction and another for claim verification using LOTR-RAG, which leverages a 130,000-document COVID-19 research corpus. An enhanced variant, SAFE (LOTR-RAG + SRAG), incorporates Self-RAG to refine retrieval via query rewriting. We evaluated both systems on 50 fake news articles (2-17 pages) containing 246 annotated claims (M = 4.922, SD = 3.186), labeled as true (14.1%), partly true (14.4%), false (27.0%), partly false (2.2%), and misleading (21.0%) by public health professionals. SAFE systems significantly outperformed baseline LLMs in all metrics (p < 0.001). For consistency (0-1 scale), SAFE (LOTR-RAG) scored 0.629, exceeding both SAFE (+SRAG) (0.577) and the baseline (0.279). In subjective evaluations (0-4 Likert scale), SAFE (LOTR-RAG) also achieved the highest average ratings in usefulness (3.640), clearness (3.800), and authenticity (3.526). Adding SRAG slightly reduced overall performance, except for a minor gain in clearness. SAFE demonstrates robust improvements in long-form COVID-19 fact-checking by addressing LLM limitations in consistency and explainability. The core LOTR-RAG design proved more effective than its SRAG-augmented variant, offering a strong foundation for scalable misinformation mitigation.

cs.IR↗

ArenaBencher: Automatic Benchmark Evolution via Multi-Model Competitive Evaluation

Benchmarks are central to measuring the capabilities of large language models and guiding model development, yet widespread data leakage from pretraining corpora undermines their validity. Models can match memorized content rather than demonstrate true generalization, which inflates scores, distorts cross-model comparisons, and misrepresents progress. We introduce ArenaBencher, a model-agnostic framework for automatic benchmark evolution that updates test cases while preserving comparability. Given an existing benchmark and a diverse pool of models to be evaluated, ArenaBencher infers the core ability of each test case, generates candidate question-answer pairs that preserve the original objective, verifies correctness and intent with an LLM as a judge, and aggregates feedback from multiple models to select candidates that expose shared weaknesses. The process runs iteratively with in-context demonstrations that steer generation toward more challenging and diagnostic cases. We apply ArenaBencher to math problem solving, commonsense reasoning, and safety domains and show that it produces verified, diverse, and fair updates that uncover new failure modes, increase difficulty while preserving test objective alignment, and improve model separability. The framework provides a scalable path to continuously evolve benchmarks in step with the rapid progress of foundation models.

cs.CL↗

Flow of Knowledge: Federated Fine-Tuning of LLMs in Healthcare under Non-IID Conditions

Large language models (LLMs) show great promise in healthcare, but their applications are hindered by data privacy restrictions and the challenges of cross-institution collaboration. Sensitive medical data cannot be centralized, while non-independent and identically distributed (non-IID) characteristics across institutions further complicate convergence and fairness. To address these issues, we present a federated fine-tuning approach based on Low-Rank Adaptation (LoRA), enabling privacy-preserving knowledge flow across institutions. The method iteratively combines local LoRA adaptation with global parameter aggregation, allowing efficient knowledge sharing without exposing raw data. A blockchain identity scheme is used for identifying individual LLM in such a distributed network. We evaluate this approach on heterogeneous and highly non-IID medical text datasets, where experiments demonstrate that federated LoRA not only enhances cross-client generalization but also improves the performance of the weakest client, achieving stable convergence and fairer outcomes. These findings highlight federated LoRA fine-tuning as a practical and effective paradigm for adapting LLMs in healthcare, offering a new path for multi-center medical AI collaboration.

cs.CE↗

Model Correlation Detection via Random Selection Probing

The growing prevalence of large language models (LLMs) and vision-language models (VLMs) has heightened the need for reliable techniques to determine whether a model has been fine-tuned from or is even identical to another. Existing similarity-based methods often require access to model parameters or produce heuristic scores without principled thresholds, limiting their applicability. We introduce Random Selection Probing (RSP), a hypothesis-testing framework that formulates model correlation detection as a statistical test. RSP optimizes textual or visual prefixes on a reference model for a random selection task and evaluates their transferability to a target model, producing rigorous p-values that quantify evidence of correlation. To mitigate false positives, RSP incorporates an unrelated baseline model to filter out generic, transferable features. We evaluate RSP across both LLMs and VLMs under diverse access conditions for reference models and test models. Experiments on fine-tuned and open-source models show that RSP consistently yields small p-values for related models while maintaining high p-values for unrelated ones. Extensive ablation studies further demonstrate the robustness of RSP. These results establish RSP as the first principled and general statistical framework for model correlation detection, enabling transparent and interpretable decisions in modern machine learning ecosystems.

cs.LG↗

FedOC: Multi-Server FL with Overlapping Client Relays in Wireless Edge Networks

Multi-server Federated Learning (FL) has emerged as a promising solution to mitigate communication bottlenecks of single-server FL. We focus on a typical multi-server FL architecture, where the regions covered by different edge servers (ESs) may overlap. A key observation of this architecture is that clients located in the overlapping areas can access edge models from multiple ESs. Building on this insight, we propose FedOC (Federated learning with Overlapping Clients), a novel framework designed to fully exploit the potential of these overlapping clients. In FedOC, overlapping clients could serve dual roles: (1) as Relay Overlapping Clients (ROCs), they forward edge models between neighboring ESs in real time to facilitate model sharing among different ESs; and (2) as Normal Overlapping Clients (NOCs), they dynamically select their initial model for local training based on the edge model delivery time, which enables indirect data fusion among different regions of ESs. The overall FedOC workflow proceeds as follows: in every round, each client trains local model based on the earliest received edge model and transmits to the respective ESs for model aggregation. Then each ES transmits the aggregated edge model to neighboring ESs through ROC relaying. Upon receiving the relayed models, each ES performs a second aggregation and subsequently broadcasts the updated model to covered clients. The existence of ROCs enables the model of each ES to be disseminated to the other ESs in a decentralized manner, which indirectly achieves intercell model and speeding up the training process, making it well-suited for latency-sensitive edge environments. Extensive experimental results show remarkable performance gains of our scheme compared to existing methods.

cs.NI↗

CodeRAG: Finding Relevant and Necessary Knowledge for Retrieval-Augmented Repository-Level Code Completion

Repository-level code completion automatically predicts the unfinished code based on the broader information from the repository. Recent strides in Code Large Language Models (code LLMs) have spurred the development of repository-level code completion methods, yielding promising results. Nevertheless, they suffer from issues such as inappropriate query construction, single-path code retrieval, and misalignment between code retriever and code LLM. To address these problems, we introduce CodeRAG, a framework tailored to identify relevant and necessary knowledge for retrieval-augmented repository-level code completion. Its core components include log probability guided query construction, multi-path code retrieval, and preference-aligned BestFit reranking. Extensive experiments on benchmarks ReccEval and CCEval demonstrate that CodeRAG significantly and consistently outperforms state-of-the-art methods. The implementation of CodeRAG is available at https://github.com/KDEGroup/CodeRAG.

cs.CL↗

Hunyuan3D Studio: End-to-End AI Pipeline for Game-Ready 3D Asset Generation

The creation of high-quality 3D assets, a cornerstone of modern game development, has long been characterized by labor-intensive and specialized workflows. This paper presents Hunyuan3D Studio, an end-to-end AI-powered content creation platform designed to revolutionize the game production pipeline by automating and streamlining the generation of game-ready 3D assets. At its core, Hunyuan3D Studio integrates a suite of advanced neural modules (such as Part-level 3D Generation, Polygon Generation, Semantic UV, etc.) into a cohesive and user-friendly system. This unified framework allows for the rapid transformation of a single concept image or textual description into a fully-realized, production-quality 3D model complete with optimized geometry and high-fidelity PBR textures. We demonstrate that assets generated by Hunyuan3D Studio are not only visually compelling but also adhere to the stringent technical requirements of contemporary game engines, significantly reducing iteration time and lowering the barrier to entry for 3D content creation. By providing a seamless bridge from creative intent to technical asset, Hunyuan3D Studio represents a significant leap forward for AI-assisted workflows in game development and interactive media.

cs.CV↗

DANCE: Resource-Efficient Neural Architecture Search with Data-Aware and Continuous Adaptation

Neural Architecture Search (NAS) has emerged as a powerful approach for automating neural network design. However, existing NAS methods face critical limitations in real-world deployments: architectures lack adaptability across scenarios, each deployment context requires costly separate searches, and performance consistency across diverse platforms remains challenging. We propose DANCE (Dynamic Architectures with Neural Continuous Evolution), which reformulates architecture search as a continuous evolution problem through learning distributions over architectural components. DANCE introduces three key innovations: a continuous architecture distribution enabling smooth adaptation, a unified architecture space with learned selection gates for efficient sampling, and a multi-stage training strategy for effective deployment optimization. Extensive experiments across five datasets demonstrate DANCE's effectiveness. Our method consistently outperforms state-of-the-art NAS approaches in terms of accuracy while significantly reducing search costs. Under varying computational constraints, DANCE maintains robust performance while smoothly adapting architectures to different hardware requirements. The code and appendix can be found at https://github.com/Applied-Machine-Learning-Lab/DANCE.

cs.LG↗

Universal Abstraction: Harnessing Frontier Models to Structure Real-World Data at Scale

A significant fraction of real-world patient information resides in unstructured clinical text. Medical abstraction extracts and normalizes key structured attributes from free-text clinical notes, which is the prerequisite for a variety of important downstream applications, including registry curation, clinical trial operations, and real-world evidence generation. Prior medical abstraction methods typically resort to building attribute-specific models, each of which requires extensive manual effort such as rule creation or supervised label annotation for the individual attribute, thus limiting scalability. In this paper, we show that existing frontier models already possess the universal abstraction capability for scaling medical abstraction to a wide range of clinical attributes. We present UniMedAbstractor (UMA), a unifying framework for zero-shot medical abstraction with a modular, customizable prompt template and the selection of any frontier large language models. Given a new attribute for abstraction, users only need to conduct lightweight prompt adaptation in UMA to adjust the specification in natural languages. Compared to traditional methods, UMA eliminates the need for attribute-specific training labels or handcrafted rules, thus substantially reducing the development time and cost. We conducted a comprehensive evaluation of UMA in oncology using a wide range of marquee attributes representing the cancer patient journey. These include relatively simple attributes typically specified within a single clinical note (e.g. performance status), as well as complex attributes requiring sophisticated reasoning across multiple notes at various time points (e.g. tumor staging). Based on a single frontier model such as GPT-4o, UMA matched or even exceeded the performance of state-of-the-art attribute-specific methods, each of which was tailored to the individual attribute.

cs.CL↗

GenFlowRL: Shaping Rewards with Generative Object-Centric Flow in Visual Reinforcement Learning

Recent advances have shown that video generation models can enhance robot learning by deriving effective robot actions through inverse dynamics. However, these methods heavily depend on the quality of generated data and struggle with fine-grained manipulation due to the lack of environment feedback. While video-based reinforcement learning improves policy robustness, it remains constrained by the uncertainty of video generation and the challenges of collecting large-scale robot datasets for training diffusion models. To address these limitations, we propose GenFlowRL, which derives shaped rewards from generated flow trained from diverse cross-embodiment datasets. This enables learning generalizable and robust policies from diverse demonstrations using low-dimensional, object-centric features. Experiments on 10 manipulation tasks, both in simulation and real-world cross-embodiment evaluations, demonstrate that GenFlowRL effectively leverages manipulation features extracted from generated object-centric flow, consistently achieving superior performance across diverse and challenging scenarios. Our Project Page: https://colinyu1.github.io/genflowrl

cs.RO↗

Exploring Scaling Laws for EHR Foundation Models

The emergence of scaling laws has profoundly shaped the development of large language models (LLMs), enabling predictable performance gains through systematic increases in model size, dataset volume, and compute. Yet, these principles remain largely unexplored in the context of electronic health records (EHRs) -- a rich, sequential, and globally abundant data source that differs structurally from natural language. In this work, we present the first empirical investigation of scaling laws for EHR foundation models. By training transformer architectures on patient timeline data from the MIMIC-IV database across varying model sizes and compute budgets, we identify consistent scaling patterns, including parabolic IsoFLOPs curves and power-law relationships between compute, model parameters, data size, and clinical utility. These findings demonstrate that EHR models exhibit scaling behavior analogous to LLMs, offering predictive insights into resource-efficient training strategies. Our results lay the groundwork for developing powerful EHR foundation models capable of transforming clinical prediction tasks and advancing personalized healthcare.

cs.CL↗

HunyuanWorld 1.0: Generating Immersive, Explorable, and Interactive 3D Worlds from Words or Pixels

Creating immersive and playable 3D worlds from texts or images remains a fundamental challenge in computer vision and graphics. Existing world generation approaches typically fall into two categories: video-based methods that offer rich diversity but lack 3D consistency and rendering efficiency, and 3D-based methods that provide geometric consistency but struggle with limited training data and memory-inefficient representations. To address these limitations, we present HunyuanWorld 1.0, a novel framework that combines the best of both worlds for generating immersive, explorable, and interactive 3D scenes from text and image conditions. Our approach features three key advantages: 1) 360° immersive experiences via panoramic world proxies; 2) mesh export capabilities for seamless compatibility with existing computer graphics pipelines; 3) disentangled object representations for augmented interactivity. The core of our framework is a semantically layered 3D mesh representation that leverages panoramic images as 360° world proxies for semantic-aware world decomposition and reconstruction, enabling the generation of diverse 3D worlds. Extensive experiments demonstrate that our method achieves state-of-the-art performance in generating coherent, explorable, and interactive 3D worlds while enabling versatile applications in virtual reality, physical simulation, game development, and interactive content creation.

cs.CV↗

DMF2Mel: A Dynamic Multiscale Fusion Network for EEG-Driven Mel Spectrogram Reconstruction

Decoding speech from brain signals is a challenging research problem. Although existing technologies have made progress in reconstructing the mel spectrograms of auditory stimuli at the word or letter level, there remain core challenges in the precise reconstruction of minute-level continuous imagined speech: traditional models struggle to balance the efficiency of temporal dependency modeling and information retention in long-sequence decoding. To address this issue, this paper proposes the Dynamic Multiscale Fusion Network (DMF2Mel), which consists of four core components: the Dynamic Contrastive Feature Aggregation Module (DC-FAM), the Hierarchical Attention-Guided Multi-Scale Network (HAMS-Net), the SplineMap attention mechanism, and the bidirectional state space module (convMamba). Specifically, the DC-FAM separates speech-related "foreground features" from noisy "background features" through local convolution and global attention mechanisms, effectively suppressing interference and enhancing the representation of transient signals. HAMS-Net, based on the U-Net framework,achieves cross-scale fusion of high-level semantics and low-level details. The SplineMap attention mechanism integrates the Adaptive Gated Kolmogorov-Arnold Network (AGKAN) to combine global context modeling with spline-based local fitting. The convMamba captures long-range temporal dependencies with linear complexity and enhances nonlinear dynamic modeling capabilities. Results on the SparrKULee dataset show that DMF2Mel achieves a Pearson correlation coefficient of 0.074 in mel spectrogram reconstruction for known subjects (a 48% improvement over the baseline) and 0.048 for unknown subjects (a 35% improvement over the baseline).Code is available at: https://github.com/fchest/DMF2Mel.

cs.SD↗