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Shivani

Publications and source records attributed to Shivani.

At least 19 recordsLinked to original sources

SPARC Segmentation to Prediction via Affine Regression and Counterfactuals

Transaction propensity prediction in B2B e commerce presents unique challenges distinct from B2C contexts, primarily due to the heterogeneous procurement behaviors of organizational entities, which violate SMOTE's implicit assumption of within class feature homogeneity. Specifically, B2B buyers exhibit multi modal procurement cycles that render linear interpolation between minority class samples structurally invalid, producing synthetic data that does not represent real purchasing behavior. This paper introduces a production deployed propensity modeling framework designed to address these complexities through two primary contributions. First, we replace conventional SMOTE based augmentation with a synthetic data generation approach leveraging Diverse Counterfactual Explanations (DiCE). This method produces minority class samples with superior distributional fidelity compared to SMOTE, as validated through quantitative proximity analysis and UMAP cluster visualization. Second, we adapt the PyPARC piecewise affine classification framework to generate calibrated propensity probabilities, facilitating the interpretable segmentation of customers into actionable risk tiers. Evaluated on two years of longitudinal data from a large scale B2B e commerce platform with a 1 to 9 class imbalance ratio, the proposed architecture achieves 93.1% precision at a decision threshold of 0.8, a 9.2 percentage point improvement over SMOTE based baselines at the same threshold (83.9%), and a 26.1 point improvement over SMOTE at threshold 0.7 (66.04%), demonstrating consistent superiority across operating points. These results demonstrate the framework's efficacy in enabling high precision marketing campaigns with significant improvements in customer activation and return on investment.

cs.LG

Learning Strategies in Particle Swarm Optimizer: A Critical Review and Performance Analysis

Nature has long inspired the development of swarm intelligence (SI), a key branch of artificial intelligence that models collective behaviors observed in biological systems for solving complex optimization problems. Particle swarm optimization (PSO) is widely adopted among SI algorithms due to its simplicity and efficiency. Despite numerous learning strategies proposed to enhance PSO's performance in terms of convergence speed, robustness, and adaptability, no comprehensive and systematic analysis of these strategies exists. We review and classify various learning strategies to address this gap, assessing their impact on optimization performance. Additionally, a comparative experimental evaluation is conducted to examine how these strategies influence PSO's search dynamics. Finally, we discuss open challenges and future directions, emphasizing the need for self-adaptive, intelligent PSO variants capable of addressing increasingly complex real-world problems.

cs.NE

Advancements in Multimodal Differential Evolution: A Comprehensive Review and Future Perspectives

Multi-modal optimization involves identifying multiple global and local optima of a function, offering valuable insights into diverse optimal solutions within the search space. Evolutionary algorithms (EAs) excel at finding multiple solutions in a single run, providing a distinct advantage over classical optimization techniques that often require multiple restarts without guarantee of obtaining diverse solutions. Among these EAs, differential evolution (DE) stands out as a powerful and versatile optimizer for continuous parameter spaces. DE has shown significant success in multi-modal optimization by utilizing its population-based search to promote the formation of multiple stable subpopulations, each targeting different optima. Recent advancements in DE for multi-modal optimization have focused on niching methods, parameter adaptation, hybridization with other algorithms including machine learning, and applications across various domains. Given these developments, it is an opportune moment to present a critical review of the latest literature and identify key future research directions. This paper offers a comprehensive overview of recent DE advancements in multimodal optimization, including methods for handling multiple optima, hybridization with EAs, and machine learning, and highlights a range of real-world applications. Additionally, the paper outlines a set of compelling open problems and future research issues from multiple perspectives

cs.NE

A Multi-operator Ensemble LSHADE with Restart and Local Search Mechanisms for Single-objective Optimization

In recent years, multi-operator and multi-method algorithms have succeeded, encouraging their combination within single frameworks. Despite promising results, there remains room for improvement as only some evolutionary algorithms (EAs) consistently excel across all optimization problems. This paper proposes mLSHADE-RL, an enhanced version of LSHADE-cnEpSin, which is one of the winners of the CEC 2017 competition in real-parameter single-objective optimization. mLSHADE-RL integrates multiple EAs and search operators to improve performance further. Three mutation strategies such as DE/current-to-pbest-weight/1 with archive, DE/current-to-pbest/1 without archive, and DE/current-to-ordpbest-weight/1 are integrated in the original LSHADE-cnEpSin. A restart mechanism is also proposed to overcome the local optima tendency. Additionally, a local search method is applied in the later phase of the evolutionary procedure to enhance the exploitation capability of mLSHADE-RL. mLSHADE-RL is tested on 30 dimensions in the CEC 2024 competition on single objective bound constrained optimization, demonstrating superior performance over other state-of-the-art algorithms in producing high-quality solutions across various optimization scenarios.

cs.NE

Investigation of Novel Preclinical Total Body PET Designed With J-PET Technology:A Simulation Study

The growing interest in human-grade total body positron emission tomography (PET) systems has also application in small animal research. Due to the existing limitations in human-based studies involving drug development and novel treatment monitoring, animal-based research became a necessary step for testing and protocol preparation. In this simulation-based study two unconventional, cost-effective small animal total body PET scanners (for mouse and rat studies) have been investigated in order to inspect their feasibility for preclinical research. They were designed with the novel technology explored by the Jagiellonian-PET (J-PET) Collaboration. Two main PET characteristics: sensitivity and spatial resolution were mainly inspected to evaluate their performance. Moreover, the impact of the scintillator dimension and time-of-flight on the latter parameter was examined in order to design the most efficient tomographs. The presented results show that for mouse TB J-PET the achievable system sensitivity is equal to 2.35% and volumetric spatial resolution to 9.46 +- 0.54 mm3, while for rat TB J-PET they are equal to 2.6% and 14.11 +- 0.80 mm3, respectively. Furthermore, it was shown that the designed tomographs are almost parallax-free systems, hence, they resolve the problem of the acceptance criterion tradeoff between enhancing spatial resolution and reducing sensitivity.

physics.med-ph

Feasibility studies for imaging e$^{+}$e$^{-}$ annihilation with modular multi-strip detectors

Studies based on imaging the annihilation of the electron (e$^{-}$) and its antiparticle positron (e$^{+}$) open up several interesting applications in nuclear medicine and fundamental research. The annihilation process involves both the direct conversion of e$^{+}$e$^{-}$ into photons and the formation of their atomically bound state, the positronium atom (Ps), which can be used as a probe for fundamental studies. With the ability to produce large quantities of Ps, manipulate them in long-lived Ps states, and image their annihilations after a free fall or after passing through atomic interferometers, this purely leptonic antimatter system can be used to perform inertial sensing studies in view of a direct test of Einstein equivalence principle. It is envisioned that modular multistrip detectors can be exploited as potential detection units for this kind of studies. In this work, we report the results of the first feasibility study performed on a e$^{+}$ beamline using two detection modules to evaluate their reconstruction performance and spatial resolution for imaging e$^{+}$e$^{-}$ annihilations and thus their applicability for gravitational studies of Ps.

physics.ins-det

Comparative studies of the sensitivities of sparse and full geometries of Total-Body PET scanners built from crystals and plastic scintillators

Background: Total-Body imaging offers high sensitivity, single-bed position, and low dose, but high construction costs limit worldwide utilization. This study compares existing and developing tomographs using plastic scintillators via simulations to propose a cost-efficient Total-Body PET scanner. Methods: Simulations of eight uEXPLORER tomographs with different scintillator materials, axial field-of-view, and detector configuration, and eight J-PET scanners with various field-of-view, plastic scintillator cross-sections, and layers were performed. Biograph Vision was also simulated. Two types of simulations were conducted with a central source and a water-filled phantom. Results: BGO crystal-based scanners showed the best sensitivity (350 cps/kBq at the center). Sparse geometry or LYSO crystals reduced sensitivity. J-PET design showed similar sensitivity to sparse LYSO detectors, with full body coverage and additional gain for brain imaging. Conclusion: The J-PET tomography system using plastic scintillators could be a cost-efficient alternative for Total-Body PET scanners, overcoming high construction costs while maintaining sensitivity

physics.med-ph

Feasibility of the J-PET to monitor range of therapeutic proton beams

Objective: The aim of this work is to investigate the feasibility of the Jagiellonian Positron Emission Tomography (J-PET) scanner for intra-treatment proton beam range monitoring. Approach: The Monte Carlo simulation studies with GATE and PET image reconstruction with CASToR were performed in order to compare six J-PET scanner geometries (three dual-heads and three cylindrical). We simulated proton irradiation of a PMMA phantom with a Single Pencil Beam (SPB) and Spread-Out Bragg Peak (SOBP) of various ranges. The sensitivity and precision of each scanner were calculated, and considering the setup's cost-effectiveness, we indicated potentially optimal geometries for the J-PET scanner prototype dedicated to the proton beam range assessment. Main results: The investigations indicate that the double-layer cylindrical and triple-layer double-head configurations are the most promising for clinical application. We found that the scanner sensitivity is of the order of 10$^{-5}$ coincidences per primary proton, while the precision of the range assessment for both SPB and SOBP irradiation plans was found below 1 mm. Among the scanners with the same number of detector modules, the best results are found for the triple-layer dual-head geometry. Significance: We performed simulation studies demonstrating that the feasibility of the J-PET detector for PET-based proton beam therapy range monitoring is possible with reasonable sensitivity and precision enabling its pre-clinical tests in the clinical proton therapy environment. Considering the sensitivity, precision and cost-effectiveness, the double-layer cylindrical and triple-layer dual-head J-PET geometry configurations seem promising for the future clinical application. Experimental tests are needed to confirm these findings.

physics.med-ph

TOF MLEM Adaptation for the Total-Body J-PET with a Realistic Analytical System Response Matrix

We report a study of the original image reconstruction algorithm based on the time-of-flight maximum likelihood expectation maximisation (TOF MLEM), developed for the total-body (TB) Jagiellonian PET (J-PET) scanners. The method is applicable to generic cylindrical or modular multi-layer layouts and is extendable to multi-photon imaging. The system response matrix (SRM) is represented as a set of analytical functions, uniquely defined for each pair of plastic scintillator strips used for the detection. A realistic resolution model (RM) in detector space is derived from fitting the Monte Carlo simulated emissions and detections of annihilation photons on oblique transverse planes. Additional kernels embedded in SRM account for TOF, parallax effect and axial smearing. The algorithm was tested on datasets, simulated in GATE for the NEMA IEC and static XCAT phantoms inside a 24-module 2-layer TB J-PET. Compared to the reference TOF MLEM with none or a shift-invariant RM, an improvement was observed, as evaluated by the analysis of image quality, difference images and ground truth metrics. We also reconstructed the data with additive contributions, pre-filtered geometrically and with non-TOF scatter correction applied. Despite some deterioration, the obtained results still capitalise on the realistic RM with better edge preservation and superior ground truth metrics. The envisioned prospects of the TOF MLEM with analytical SRM include its application in multi-photon imaging and further upgrade to account for the non-collinearity, positron range and other factors.

physics.med-ph

J-PET detection modules based on plastic scintillators for performing studies with positron and positronium beams

The J-PET detector, which consists of inexpensive plastic scintillators, has demonstrated its potential in the study of fundamental physics. In recent years, a prototype with 192 plastic scintillators arranged in 3 layers has been optimized for the study of positronium decays. This allows performing precision tests of discrete symmetries (C, P, T) in the decays of positronium atoms. Moreover, thanks to the possibility of measuring the polarization direction of the photon based on Compton scattering, the predicted entanglement between the linear polarization of annihilation photons in positronium decays can also be studied. Recently, a new J-PET prototype was commissioned, based on a modular design of detection units. Each module consists of 13 plastic scintillators and can be used as a stand-alone, compact and portable detection unit. In this paper, the main features of the J-PET detector, the modular prototype and their applications for possible studies with positron and positronium beams are discussed. Preliminary results of the first test experiment performed on two detection units in the continuous positron beam recently developed at the Antimatter Laboratory (AML) of Trento are also reported.

physics.ins-det

Realistic Total-Body J-PET Geometry Optimization -- Monte Carlo Study

Total-Body PET is one of the most promising medical diagnostics modalities. The high sensitivity provided by Total-Body technology can be advantageous for novel tomography methods like positronium imaging. Several efforts are ongoing to lower the price of the TB-PET systems. Among the alternatives, the Jagiellonian PET (J-PET) technology, based on plastic scintillator strips, offers a low-cost alternative. The work aimed to compare five Total-Body J-PET geometries as a possible next generation J-PET scanner design. We present comparative studies of performance characteristics of the cost-effective Total-Body PET scanners using J-PET technology. We investigated in silico five Total-Body scanner geometries. Monte Carlo simulations of the XCAT phantom, the 2-meter sensitivity line source and positronium sensitivity phantoms were performed. We compared the sensitivity profiles for 2-gamma and 3-gamma tomography, relative cost of the setups and performed quantitative analysis of the reconstructed images. The analysis of the reconstructed XCAT images reveals the superiority of the seven-ring scanners over the three-ring setups. However, the three-ring scanners would be approximately 2-3 times cheaper. The peak sensitivity values for two-gamma vary from 20 to 34 cps/kBq. The sensitivity curves for the positronium tomography have a similar shape to the two-gamma sensitivity profiles. The peak values are lower compared to the two-gamma cases, from about 20-28 times, with a maximum of 1.66 cps/kBq. The results show the feasibility of multi-organ imaging of all the systems to be considered for the next generation of TB J-PET designs. The relative cost for all the scanners is about 10-4 times lower compared to the cost of the uExplorer. These properties coupled together with J-PET cost-effectiveness, make the J-PET technology an attractive solution for broad application in clinics.

physics.med-ph

Positronium imaging with the novel multiphoton PET scanner

In vivo assessment of cancer and precise location of altered tissues at initial stages of molecular disorders are important diagnostic challenges. Positronium is copiously formed in the free molecular spaces in the patient's body during positron emission tomography (PET). The positronium properties vary according to the size of inter- and intramolecular voids and the concentration of molecules in them such as, e.g., molecular oxygen, O2; therefore, positronium imaging may provide information about disease progression during the initial stages of molecular alterations. Current PET systems do not allow acquisition of positronium images. This study presents a new method that enables positronium imaging by simultaneous registration of annihilation photons and deexcitation photons from pharmaceuticals labeled with radionuclides. The first positronium imaging of a phantom built from cardiac myxoma and adipose tissue is demonstrated. It is anticipated that positronium imaging will substantially enhance the specificity of PET diagnostics.

physics.med-ph

Optimisation of the event-based TOF filtered back-projection for online imaging in total-body J-PET

We perform a parametric study of the newly developed time-of-flight (TOF) image reconstruction algorithm, proposed for the real-time imaging in total-body Jagiellonian PET (J-PET) scanners. The asymmetric 3D filtering kernel is applied at each most likely position of electron-positron annihilation, estimated from the emissions of back-to-back $\gamma$-photons. The optimisation of its parameters is studied using Monte Carlo simulations of a 1-mm spherical source, NEMA IEC and XCAT phantoms inside the ideal J-PET scanner. The combination of high-pass filters which included the TOF filtered back-projection (FBP), resulted in spatial resolution, 1.5 $\times$ higher in the axial direction than for the conventional 3D FBP. For realistic $10$-minute scans of NEMA IEC and XCAT, which require a trade-off between the noise and spatial resolution, the need for Gaussian TOF kernel components, coupled with median post-filtering, is demonstrated. The best sets of 3D filter parameters were obtained by the Nelder-Mead minimisation of the mean squared error between the resulting and reference images. The approach allows training the reconstruction algorithm for custom scans, using the IEC phantom, when the temporal resolution is below 50 ps. The image quality parameters, estimated for the best outcomes, were systematically better than for the non-TOF FBP.

physics.med-ph

Projections for COVID-19 spread in India and its worst affected five states using the Modified SEIRD and LSTM models

The last leg of the year 2019 gave rise to a virus named COVID-19 (Corona Virus Disease 2019). Since the beginning of this infection in India, the government implemented several policies and restrictions to curtail its spread among the population. As the time passed, these restrictions were relaxed and people were advised to follow precautionary measures by themselves. These timely decisions taken by the Indian government helped in decelerating the spread of COVID-19 to a large extent. Despite these decisions, the pandemic continues to spread and hence, there is an urgent need to plan and control the spread of this disease. This is possible by finding the future predictions about the spread. Scientists across the globe are working towards estimating the future growth of COVID-19. This paper proposes a Modified SEIRD (Susceptible-Exposed-Infected-Recovered-Deceased) model for projecting COVID-19 infections in India and its five states having the highest number of total cases. In this model, exposed compartment contains individuals which may be asymptomatic but infectious. Deep Learning based Long Short-Term Memory (LSTM) model has also been used in this paper to perform short-term projections. The projections obtained from the proposed Modified SEIRD model have also been compared with the projections made by LSTM for next 30 days. The epidemiological data up to 15th August 2020 has been used for carrying out predictions in this paper. These predictions will help in arranging adequate medical infrastructure and providing proper preventive measures to handle the current pandemic. The effect of different lockdowns imposed by the Indian government has also been used in modelling and analysis in the proposed Modified SEIRD model. The results presented in this paper will act as a beacon for future policy-making to control the COVID-19 spread in India.

q-bio.PE

Synchronisation and calibration of the 24-modules J-PET prototype with 300~mm axial field of view

Research conducted in the framework of the J-PET project aims to develop a cost-effective total-body positron emission tomography scanner. As a first step on the way to construct a full-scale J-PET tomograph from long strips of plastic scintillators, a 24-strip prototype was built and tested. The prototype consists of detection modules arranged axially forming a cylindrical diagnostic chamber with the inner diameter of 360 mm and the axial field-of-view of 300 mm. Promising perspectives for a low-cost construction of a total-body PET scanner are opened due to an axial arrangement of strips of plastic scintillators, wchich have a small light attenuation, superior timing properties, and the possibility of cost-effective increase of the axial field-of-view. The presented prototype comprises dedicated solely digital front-end electronic circuits and a triggerless data acquisition system which required development of new calibration methods including time, thresholds and gain synchronization. The system and elaborated calibration methods including first results of the 24-module J-PET prototype are presented and discussed. The achieved coincidence resolving time equals to CRT = 490 $\pm$ 9 ps. This value can be translated to the position reconstruction accuracy $\sigma(\Delta l) =$ 18 mm which is fairly position-independent.

physics.ins-det

The J-PET detector -- a tool for precision studies of ortho-positronium decays

The J-PET tomograph is constructed from plastic scintillator strips arranged axially in concentric cylindrical layers. It enables investigations of positronium decays by measurement of the time, position, polarization and energy deposited by photons in the scintillators, in contrast to studies conducted so far with crystal and semiconductor based detection systems where the key selection of events is based on the measurement of the photons energies. In this article we show that the J-PET tomograph system is capable of exclusive measurements of the decays of ortho-positronium atoms. We present the first positronium production results, its lifetime distribution measurements and discuss estimation of the influence of various background sources. The tomograph s performance demonstrated here makes it suitable for precision studies of positronium decays including entanglement of the final state photons, positron annihilation lifetime spectroscopy plus molecular imaging diagnostics.

physics.ins-det

Development of J-PEM for breast cancer detection and diagnosis using positronium imaging

The purpose of the presented investigations is to design, construct and establish the characteristic performance of the Jagiellonian Positron Emission Mammography(J-PEM), being designed for the detection and diagnosis of breast cancer. Its construction is based on a novel idea of PET tomography based on plastic scintillators and wavelength shifter (WLS) and a new concept of positronium imaging. We have prepared a simulation program based on Monte Carlo methods for optimizing the geometry and material of the J-PEM prototype. Here we present the first results from the simulations and a brief review of the state of art of breast imaging modalities and their characteristics motivating our investigation.

physics.med-ph

Estimating relationship between the Time Over Threshold and energy loss by photons in plastic scintillators used in the J-PET scanner

Time-Over-Threshold (TOT) technique is being used widely due to its implications in developing the multi channel readouts mainly when fast signal processing is required. Using TOT technique as a measure of energy loss instead of charge integration methods significantly reduces the signals readout cost by combining the time and energy information. Therefore, this approach can potentially be used in J-PET tomograph which is build from plastic scintillators characterized by fast light signals. The drawback in adopting this technique is lying in the non-linear correlation between input energy loss and TOT of the signal. The main motivation behind this work is to develop the relationship between TOT and energy loss and validate it with the J-PET tomograph. The experiment was performed using the $^{22}$Na beta emitter source placed in the center of the J-PET tomograph. One can obtain primary photons of two different energies: 511 keV photon from the annihilation of positron (direct annihilation or through the formation of para-Positronim atom or pick-off process of ortho-Positronium atoms), and 1275 keV prompt photon. This allows to study the correlation between TOT values and energy loss for energy range up to 1000 keV. As the photon interacts dominantly via Compton scattering inside the plastic scintillator, there is no direct information of primary photon energy. However, using the J-PET geometry one can measure the scattering angle of the interacting photon. Since, $^{22}$Na source emits photons of two different energies, it is required to know unambiguously the energy of incident photons and its corresponding scattering angle for the estimation of energy deposition. In this work, the relationship between Time Over Threshold and energy loss by interacting photons inside the plastic scintillators used in J-PET scanner is established for a energy deposited range 100-1000 keV

physics.ins-det