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Shiying Li

Publications and source records attributed to Shiying Li.

At least 19 recordsLinked to original sources

A Unified Geometric Framework for Developmental Analysis of Spatial Transcriptomic Data

High-throughput single-cell and spatial transcriptomic technologies provide high-resolution snapshots of heterogeneous cellular states, but their destructive nature prevents repeated measurements of the same cells over time. Consequently, temporal and spatial dynamics must be inferred from independently sampled, unaligned cell populations, making it challenging to reconstruct developmental trajectories. Optimal transport (OT) offers a geometric framework for aligning cell populations and inferring developmental trajectories, but many existing approaches focus on modeling the evolution of distributions of cells in gene expression space rather than the relational structure encoded by gene expression networks. To address this limitation, we introduce a geometric framework for analyzing the spatiotemporal evolution of gene expression networks through embeddings in Gromov--Wasserstein (GW) space. By representing each developmental stage as a graph combining gene expression and spatial proximity, our approach enables comparisons of network structure across time, continuous interpolation between developmental stages via GW geodesics, and quantification of network-level changes using Ollivier-Ricci curvature. We evaluate our framework on a spatiotemporal transcriptomic \textit{Drosophila} dataset and show that GW geodesic interpolations reproduce main trends in curvature dynamics observed in empirical gene expression networks. Agreement with higher-order Co-Optimal Transport (COOT) distances, which jointly represent spatial and temporal information, further validates the framework and suggests that hypernetwork representations successfully record salient biological changes across time. In general, our approach provides a unified geometric approach to study dynamically evolving biological networks.

stat.ML

Wasserstein Mahalanobis Distances for Recovering Latent Geometry

The Mahalanobis distance is a fundamental covariance-adapted metric for multivariate data and plays a central role in recovering latent geometry from nonlinear observations. We extend this principle from vector-valued data to probability measures by introducing a Wasserstein Mahalanobis distance. Our construction replaces Euclidean displacement vectors with optimal transport displacement fields and local covariance matrices with covariance operators defined on Wasserstein tangent spaces. We show that this construction inherits the geometry-recovery property underlying nonlinear independent component analysis. In particular, for Gaussian measures with common covariance transformed by a smooth nonlinear pushforward, the proposed Wasserstein Mahalanobis distance approximates the classical Mahalanobis distance between the transformed latent means. The correspondence is exact for affine transformations and holds up to controlled higher-order error terms for general smooth transformations. These results establish a distribution-valued analog of classical Mahalanobis geometry and provide theoretical support for covariance-adapted learning directly in Wasserstein space. Numerical experiments confirm the theoretical predictions and demonstrate accurate recovery of latent geometric structure.

math.OC

Persistent Homology for Labeled Datasets: Gromov-Hausdorff Stability and Generalized Landscapes

Techniques from metric geometry have become fundamental tools in modern mathematical data science, providing principled methods for comparing datasets modeled as finite metric spaces. Two of the central tools in this area are the Gromov-Hausdorff distance and persistent homology, both of which yield isometry-invariant notions of distance between datasets. However, these frameworks do not account for categorical labels, which are intrinsic to many real-world datasets, such as labeled images, pre-clustered data, and semantically segmented shapes. In this paper, we introduce a general framework for labeled metric spaces and develop new notions of Gromov-Hausdorff distance and persistent homology which are adapted to this setting. Our main result shows that our persistent homology construction is stable with respect to our novel notion of Gromov-Hausdorff distance, extending a classic result in topological data analysis. To facilitate computation, we also introduce a labeled version of persistence landscapes and show that the landscape map is Lipschitz.

math.AT

MARMOT: Masked Autoencoder for Modeling Transient Imaging

Pretrained models have demonstrated impressive success in many modalities such as language and vision. Recent works facilitate the pretraining paradigm in imaging research. Transients are a novel modality, which are captured for an object as photon counts versus arrival times using a precisely time-resolved sensor. In particular for non-line-of-sight (NLOS) scenarios, transients of hidden objects are measured beyond the sensor's direct line of sight. Using NLOS transients, the majority of previous works optimize volume density or surfaces to reconstruct the hidden objects and do not transfer priors learned from datasets. In this work, we present a masked autoencoder for modeling transient imaging, or MARMOT, to facilitate NLOS applications. Our MARMOT is a self-supervised model pretrianed on massive and diverse NLOS transient datasets. Using a Transformer-based encoder-decoder, MARMOT learns features from partially masked transients via a scanning pattern mask (SPM), where the unmasked subset is functionally equivalent to arbitrary sampling, and predicts full measurements. Pretrained on TransVerse-a synthesized transient dataset of 500K 3D models-MARMOT adapts to downstream imaging tasks using direct feature transfer or decoder finetuning. Comprehensive experiments are carried out in comparisons with state-of-the-art methods. Quantitative and qualitative results demonstrate the efficiency of our MARMOT.

cs.CV

VividListener: Expressive and Controllable Listener Dynamics Modeling for Multi-Modal Responsive Interaction

Generating responsive listener head dynamics with nuanced emotions and expressive reactions is crucial for practical dialogue modeling in various virtual avatar animations. Previous studies mainly focus on the direct short-term production of listener behavior. They overlook the fine-grained control over motion variations and emotional intensity, especially in long-sequence modeling. Moreover, the lack of long-term and large-scale paired speaker-listener corpora including head dynamics and fine-grained multi-modality annotations (e.g., text-based expression descriptions, emotional intensity) also limits the application of dialogue modeling.Therefore, we first newly collect a large-scale multi-turn dataset of 3D dyadic conversation containing more than 1.4M valid frames for multi-modal responsive interaction, dubbed ListenerX. Additionally, we propose VividListener, a novel framework enabling fine-grained, expressive and controllable listener dynamics modeling. This framework leverages multi-modal conditions as guiding principles for fostering coherent interactions between speakers and listeners.Specifically, we design the Responsive Interaction Module (RIM) to adaptively represent the multi-modal interactive embeddings. RIM ensures the listener dynamics achieve fine-grained semantic coordination with textual descriptions and adjustments, while preserving expressive reaction with speaker behavior. Meanwhile, we design the Emotional Intensity Tags (EIT) for emotion intensity editing with multi-modal information integration, applying to both text descriptions and listener motion amplitude.Extensive experiments conducted on our newly collected ListenerX dataset demonstrate that VividListener achieves state-of-the-art performance, realizing expressive and controllable listener dynamics.

cs.CV

TransiT: Transient Transformer for Non-line-of-sight Videography

High quality and high speed videography using Non-Line-of-Sight (NLOS) imaging benefit autonomous navigation, collision prevention, and post-disaster search and rescue tasks. Current solutions have to balance between the frame rate and image quality. High frame rates, for example, can be achieved by reducing either per-point scanning time or scanning density, but at the cost of lowering the information density at individual frames. Fast scanning process further reduces the signal-to-noise ratio and different scanning systems exhibit different distortion characteristics. In this work, we design and employ a new Transient Transformer architecture called TransiT to achieve real-time NLOS recovery under fast scans. TransiT directly compresses the temporal dimension of input transients to extract features, reducing computation costs and meeting high frame rate requirements. It further adopts a feature fusion mechanism as well as employs a spatial-temporal Transformer to help capture features of NLOS transient videos. Moreover, TransiT applies transfer learning to bridge the gap between synthetic and real-measured data. In real experiments, TransiT manages to reconstruct from sparse transients of $16 \times 16$ measured at an exposure time of 0.4 ms per point to NLOS videos at a $64 \times 64$ resolution at 10 frames per second. We will make our code and dataset available to the community.

cs.CV

Metric properties of partial and robust Gromov-Wasserstein distances

The Gromov-Wasserstein (GW) distances define a family of metrics, based on ideas from optimal transport, which enable comparisons between probability measures defined on distinct metric spaces. They are particularly useful in areas such as network analysis and geometry processing, as computation of a GW distance involves solving for registration between the objects which minimizes geometric distortion. Although GW distances have proven useful for various applications in the recent machine learning literature, it has been observed that they are inherently sensitive to outlier noise and cannot accommodate partial matching. This has been addressed by various constructions building on the GW framework; in this article, we focus specifically on a natural relaxation of the GW optimization problem, introduced by Chapel et al., which is aimed at addressing exactly these shortcomings. Our goal is to understand the theoretical properties of this relaxed optimization problem, from the viewpoint of metric geometry. While the relaxed problem fails to induce a metric, we derive precise characterizations of how it fails the axioms of non-degeneracy and triangle inequality. These observations lead us to define a novel family of distances, whose construction is inspired by the Prokhorov and Ky Fan distances, as well as by the recent work of Raghvendra et al.\ on robust versions of classical Wasserstein distance. We show that our new distances define true metrics, that they induce the same topology as the GW distances, and that they enjoy additional robustness to perturbations. These results provide a mathematically rigorous basis for using our robust partial GW distances in applications where outliers and partial matching are concerns.

math.MG

SAM-OCTA2: Layer Sequence OCTA Segmentation with Fine-tuned Segment Anything Model 2

Segmentation of indicated targets aids in the precise analysis of optical coherence tomography angiography (OCTA) samples. Existing segmentation methods typically perform on 2D projection targets, making it challenging to capture the variance of segmented objects through the 3D volume. To address this limitation, the low-rank adaptation technique is adopted to fine-tune the Segment Anything Model (SAM) version 2, enabling the tracking and segmentation of specified objects across the OCTA scanning layer sequence. To further this work, a prompt point generation strategy in frame sequence and a sparse annotation method to acquire retinal vessel (RV) layer masks are proposed. This method is named SAM-OCTA2 and has been experimented on the OCTA-500 dataset. It achieves state-of-the-art performance in segmenting the foveal avascular zone (FAZ) on regular 2D en-face and effectively tracks local vessels across scanning layer sequences. The code is available at: https://github.com/ShellRedia/SAM-OCTA2.

cs.CV

Snake with Shifted Window: Learning to Adapt Vessel Pattern for OCTA Segmentation

Segmenting specific targets or structures in optical coherence tomography angiography (OCTA) images is fundamental for conducting further pathological studies. The retinal vascular layers are rich and intricate, and such vascular with complex shapes can be captured by the widely-studied OCTA images. In this paper, we thus study how to use OCTA images with projection vascular layers to segment retinal structures. To this end, we propose the SSW-OCTA model, which integrates the advantages of deformable convolutions suited for tubular structures and the swin-transformer for global feature extraction, adapting to the characteristics of OCTA modality images. Our model underwent testing and comparison on the OCTA-500 dataset, achieving state-of-the-art performance. The code is available at: https://github.com/ShellRedia/Snake-SWin-OCTA.

eess.IV

SAM-OCTA: Prompting Segment-Anything for OCTA Image Segmentation

Segmenting specific targets or biomarkers is necessary to analyze optical coherence tomography angiography (OCTA) images. Previous methods typically segment all the targets in an OCTA sample, such as retinal vessels (RVs). Although these methods perform well in accuracy and precision, OCTA analyses often focusing local information within the images which has not been fulfilled. In this paper, we propose a method called SAM-OCTA for local segmentation in OCTA images. The method fine-tunes a pre-trained segment anything model (SAM) using low-rank adaptation (LoRA) and utilizes prompt points for local RVs, arteries, and veins segmentation in OCTA. To explore the effect and mechanism of prompt points, we set up global and local segmentation modes with two prompt point generation strategies, namely random selection and special annotation. Considering practical usage, we conducted extended experiments with different model scales and analyzed the model performance before and after fine-tuning besides the general segmentation task. From comprehensive experimental results with the OCTA-500 dataset, our SAM-OCTA method has achieved state-of-the-art performance in common OCTA segmentation tasks related to RV and FAZ, and it also performs accurate segmentation of artery-vein and local vessels. The code is available at https://github.com/ShellRedia/SAM-OCTA-extend.

cs.LG

Linear optimal transport subspaces for point set classification

Learning from point sets is an essential component in many computer vision and machine learning applications. Native, unordered, and permutation invariant set structure space is challenging to model, particularly for point set classification under spatial deformations. Here we propose a framework for classifying point sets experiencing certain types of spatial deformations, with a particular emphasis on datasets featuring affine deformations. Our approach employs the Linear Optimal Transport (LOT) transform to obtain a linear embedding of set-structured data. Utilizing the mathematical properties of the LOT transform, we demonstrate its capacity to accommodate variations in point sets by constructing a convex data space, effectively simplifying point set classification problems. Our method, which employs a nearest-subspace algorithm in the LOT space, demonstrates label efficiency, non-iterative behavior, and requires no hyper-parameter tuning. It achieves competitive accuracies compared to state-of-the-art methods across various point set classification tasks. Furthermore, our approach exhibits robustness in out-of-distribution scenarios where training and test distributions vary in terms of deformation magnitudes.

cs.CV

Visual Decoding and Reconstruction via EEG Embeddings with Guided Diffusion

How to decode human vision through neural signals has attracted a long-standing interest in neuroscience and machine learning. Modern contrastive learning and generative models improved the performance of visual decoding and reconstruction based on functional Magnetic Resonance Imaging (fMRI). However, the high cost and low temporal resolution of fMRI limit their applications in brain-computer interfaces (BCIs), prompting a high need for visual decoding based on electroencephalography (EEG). In this study, we present an end-to-end EEG-based visual reconstruction zero-shot framework, consisting of a tailored brain encoder, called the Adaptive Thinking Mapper (ATM), which projects neural signals from different sources into the shared subspace as the clip embedding, and a two-stage multi-pipe EEG-to-image generation strategy. In stage one, EEG is embedded to align the high-level clip embedding, and then the prior diffusion model refines EEG embedding into image priors. A blurry image also decoded from EEG for maintaining the low-level feature. In stage two, we input both the high-level clip embedding, the blurry image and caption from EEG latent to a pre-trained diffusion model. Furthermore, we analyzed the impacts of different time windows and brain regions on decoding and reconstruction. The versatility of our framework is demonstrated in the magnetoencephalogram (MEG) data modality. The experimental results indicate that our EEG-based visual zero-shot framework achieves SOTA performance in classification, retrieval and reconstruction, highlighting the portability, low cost, and high temporal resolution of EEG, enabling a wide range of BCI applications. Our code is available at https://github.com/ncclab-sustech/EEG_Image_decode.

cs.HC

Approximation properties of slice-matching operators

Iterative slice-matching procedures are efficient schemes for transferring a source measure to a target measure, especially in high dimensions. These schemes have been successfully used in applications such as color transfer and shape retrieval, and are guaranteed to converge under regularity assumptions. In this paper, we explore approximation properties related to a single step of such iterative schemes by examining an associated slice-matching operator, depending on a source measure, a target measure, and slicing directions. In particular, we demonstrate an invariance property with respect to the source measure, an equivariance property with respect to the target measure, and Lipschitz continuity concerning the slicing directions. We furthermore establish error bounds corresponding to approximating the target measure by one step of the slice-matching scheme and characterize situations in which the slice-matching operator recovers the optimal transport map between two measures. We also investigate connections to affine registration problems with respect to (sliced) Wasserstein distances. These connections can be also be viewed as extensions to the invariance and equivariance properties of the slice-matching operator and illustrate the extent to which slice-matching schemes incorporate affine effects.

math.NA

SAM-OCTA: A Fine-Tuning Strategy for Applying Foundation Model to OCTA Image Segmentation Tasks

In the analysis of optical coherence tomography angiography (OCTA) images, the operation of segmenting specific targets is necessary. Existing methods typically train on supervised datasets with limited samples (approximately a few hundred), which can lead to overfitting. To address this, the low-rank adaptation technique is adopted for foundation model fine-tuning and proposed corresponding prompt point generation strategies to process various segmentation tasks on OCTA datasets. This method is named SAM-OCTA and has been experimented on the publicly available OCTA-500 dataset. While achieving state-of-the-art performance metrics, this method accomplishes local vessel segmentation as well as effective artery-vein segmentation, which was not well-solved in previous works. The code is available at: https://github.com/ShellRedia/SAM-OCTA.

cs.CV

An Accurate and Efficient Neural Network for OCTA Vessel Segmentation and a New Dataset

Optical coherence tomography angiography (OCTA) is a noninvasive imaging technique that can reveal high-resolution retinal vessels. In this work, we propose an accurate and efficient neural network for retinal vessel segmentation in OCTA images. The proposed network achieves accuracy comparable to other SOTA methods, while having fewer parameters and faster inference speed (e.g. 110x lighter and 1.3x faster than U-Net), which is very friendly for industrial applications. This is achieved by applying the modified Recurrent ConvNeXt Block to a full resolution convolutional network. In addition, we create a new dataset containing 918 OCTA images and their corresponding vessel annotations. The data set is semi-automatically annotated with the help of Segment Anything Model (SAM), which greatly improves the annotation speed. For the benefit of the community, our code and dataset can be obtained from https://github.com/nhjydywd/OCTA-FRNet.

eess.IV

Nonrigid Object Contact Estimation With Regional Unwrapping Transformer

Acquiring contact patterns between hands and nonrigid objects is a common concern in the vision and robotics community. However, existing learning-based methods focus more on contact with rigid ones from monocular images. When adopting them for nonrigid contact, a major problem is that the existing contact representation is restricted by the geometry of the object. Consequently, contact neighborhoods are stored in an unordered manner and contact features are difficult to align with image cues. At the core of our approach lies a novel hand-object contact representation called RUPs (Region Unwrapping Profiles), which unwrap the roughly estimated hand-object surfaces as multiple high-resolution 2D regional profiles. The region grouping strategy is consistent with the hand kinematic bone division because they are the primitive initiators for a composite contact pattern. Based on this representation, our Regional Unwrapping Transformer (RUFormer) learns the correlation priors across regions from monocular inputs and predicts corresponding contact and deformed transformations. Our experiments demonstrate that the proposed framework can robustly estimate the deformed degrees and deformed transformations, which makes it suitable for both nonrigid and rigid contact.

cs.CV

The Radon Signed Cumulative Distribution Transform and its applications in classification of Signed Images

Here we describe a new image representation technique based on the mathematics of transport and optimal transport. The method relies on the combination of the well-known Radon transform for images and a recent signal representation method called the Signed Cumulative Distribution Transform. The newly proposed method generalizes previous transport-related image representation methods to arbitrary functions (images), and thus can be used in more applications. We describe the new transform, and some of its mathematical properties and demonstrate its ability to partition image classes with real and simulated data. In comparison to existing transport transform methods, as well as deep learning-based classification methods, the new transform more accurately represents the information content of signed images, and thus can be used to obtain higher classification accuracies. The implementation of the proposed method in Python language is integrated as a part of the software package PyTransKit, available on Github.

cs.IT

Measure transfer via stochastic slicing and matching

This paper studies iterative schemes for measure transfer and approximation problems, which are defined through a slicing-and-matching procedure. Similar to the sliced Wasserstein distance, these schemes benefit from the availability of closed-form solutions for the one-dimensional optimal transport problem and the associated computational advantages. While such schemes have already been successfully utilized in data science applications, not too many results on their convergence are available. The main contribution of this paper is an almost sure convergence proof for stochastic slicing-and-matching schemes. The proof builds on an interpretation as a stochastic gradient descent scheme on the Wasserstein space. Numerical examples on step-wise image morphing are demonstrated as well.

math.NA