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Shuqiang Wang

Publications and source records attributed to Shuqiang Wang.

At least 37 records · Page 2Linked to original sources

PTSM: Physiology-aware and Task-invariant Spatio-temporal Modeling for Cross-Subject EEG Decoding

Cross-subject electroencephalography (EEG) decoding remains a fundamental challenge in brain-computer interface (BCI) research due to substantial inter-subject variability and the scarcity of subject-invariant representations. This paper proposed PTSM (Physiology-aware and Task-invariant Spatio-temporal Modeling), a novel framework for interpretable and robust EEG decoding across unseen subjects. PTSM employs a dual-branch masking mechanism that independently learns personalized and shared spatio-temporal patterns, enabling the model to preserve individual-specific neural characteristics while extracting task-relevant, population-shared features. The masks are factorized across temporal and spatial dimensions, allowing fine-grained modulation of dynamic EEG patterns with low computational overhead. To further address representational entanglement, PTSM enforces information-theoretic constraints that decompose latent embeddings into orthogonal task-related and subject-related subspaces. The model is trained end-to-end via a multi-objective loss integrating classification, contrastive, and disentanglement objectives. Extensive experiments on cross-subject motor imagery datasets demonstrate that PTSM achieves strong zero-shot generalization, outperforming state-of-the-art baselines without subject-specific calibration. Results highlight the efficacy of disentangled neural representations for achieving both personalized and transferable decoding in non-stationary neurophysiological settings.

cs.LG↗

Brain Network Analysis Based on Fine-tuned Self-supervised Model for Brain Disease Diagnosis

Functional brain network analysis has become an indispensable tool for brain disease analysis. It is profoundly impacted by deep learning methods, which can characterize complex connections between ROIs. However, the research on foundation models of brain network is limited and constrained to a single dimension, which restricts their extensive application in neuroscience. In this study, we propose a fine-tuned brain network model for brain disease diagnosis. It expands brain region representations across multiple dimensions based on the original brain network model, thereby enhancing its generalizability. Our model consists of two key modules: (1)an adapter module that expands brain region features across different dimensions. (2)a fine-tuned foundation brain network model, based on self-supervised learning and pre-trained on fMRI data from thousands of participants. Specifically, its transformer block is able to effectively extract brain region features and compute the inter-region associations. Moreover, we derive a compact latent representation of the brain network for brain disease diagnosis. Our downstream experiments in this study demonstrate that the proposed model achieves superior performance in brain disease diagnosis, which potentially offers a promising approach in brain network analysis research.

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Generative Artificial Intelligence in Medical Imaging: Foundations, Progress, and Clinical Translation

Generative artificial intelligence (AI) is rapidly transforming medical imaging by enabling capabilities such as data synthesis, image enhancement, modality translation, and spatiotemporal modeling. This review presents a comprehensive and forward-looking synthesis of recent advances in generative modeling including generative adversarial networks (GANs), variational autoencoders (VAEs), diffusion models, and emerging multimodal foundation architectures and evaluates their expanding roles across the clinical imaging continuum. We systematically examine how generative AI contributes to key stages of the imaging workflow, from acquisition and reconstruction to cross-modality synthesis, diagnostic support, and treatment planning. Emphasis is placed on both retrospective and prospective clinical scenarios, where generative models help address longstanding challenges such as data scarcity, standardization, and integration across modalities. To promote rigorous benchmarking and translational readiness, we propose a three-tiered evaluation framework encompassing pixel-level fidelity, feature-level realism, and task-level clinical relevance. We also identify critical obstacles to real-world deployment, including generalization under domain shift, hallucination risk, data privacy concerns, and regulatory hurdles. Finally, we explore the convergence of generative AI with large-scale foundation models, highlighting how this synergy may enable the next generation of scalable, reliable, and clinically integrated imaging systems. By charting technical progress and translational pathways, this review aims to guide future research and foster interdisciplinary collaboration at the intersection of AI, medicine, and biomedical engineering.

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Full-Duplex Integrated Sensing, Communication, and Computation over Low-Altitude Wireless Networks

With low-altitude economies emerging as a pivotal sector, this study explores an integrated sensing, communication, and computation system over low-altitude wireless networks. A full-duplex autonomous aerial vehicle (AAV) operates as an AAV-enabled low-altitude platform (ALAP), concurrently executing data transmission, target sensing, and mobile edge computing services. To minimize systemic energy consumption under sensing beampattern constraints and computational demands, we formulate an optimization problem coordinating task allocation, computation resource allocation, and transmit/receive beamforming. Given the non-convexity and highly variable coupling, an efficient iterative convex approximation framework based on alternating optimization decomposes the problem into tractable subproblems. Moreover, the convergence and computational complexity of the proposed algorithm are rigorously analyzed. Simulations verify up to 54.12\% energy savings versus benchmarks.

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Empowering Functional Neuroimaging: A Pre-trained Generative Framework for Unified Representation of Neural Signals

Multimodal functional neuroimaging enables systematic analysis of brain mechanisms and provides discriminative representations for brain-computer interface (BCI) decoding. However, its acquisition is constrained by high costs and feasibility limitations. Moreover, underrepresentation of specific groups undermines fairness of BCI decoding model. To address these challenges, we propose a unified representation framework for multimodal functional neuroimaging via generative artificial intelligence (AI). By mapping multimodal functional neuroimaging into a unified representation space, the proposed framework is capable of generating data for acquisition-constrained modalities and underrepresented groups. Experiments show that the framework can generate data consistent with real brain activity patterns, provide insights into brain mechanisms, and improve performance on downstream tasks. More importantly, it can enhance model fairness by augmenting data for underrepresented groups. Overall, the framework offers a new paradigm for decreasing the cost of acquiring multimodal functional neuroimages and enhancing the fairness of BCI decoding models.

cs.CV↗

A Pre-trained Framework for Multilingual Brain Decoding Using Non-invasive Recordings

Brain-computer interfaces (BCIs) with speech decoding from brain recordings have broad application potential in fields such as clinical rehabilitation and cognitive neuroscience. However, current decoding methods remain limited to single-language, single-subject, and single neuroimaging modality settings, restricting their clinical applicability and generalizability. Here we propose a joint multilingual, multi-subject and multimodal decoding framework. It maps diverse brain recordings into a unified semantic space defined by a pre-trained multilingual model (PMM), enabling decoding across multiple languages, multiple subjects and multiple neuroimaging modalities. The proposed framework is validated using non-invasive brain recordings from 159 participants across four languages. Experimental results show that it exhibits strong generalization across multilingual, multi-subject, and multimodal settings. More importantly, the proposed framework can promote linguistic fairness, which is vital for underrepresented languages in BCI applications. The unified semantic space enables cross-lingual mapping enhancement, allowing the framework to boost the decoding performance of underrepresented languages, thereby promoting linguistic fairness. Overall, the proposed framework establishes a new potential paradigm for brain decoding, opening new paths for broader applications of BCI.

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Coordinated Beamforming for RIS-Empowered ISAC Systems over Secure Low-Altitude Networks

Emerging as a cornerstone for next-generation wireless networks, integrated sensing and communication (ISAC) systems demand innovative solutions to balance spectral efficiency and sensing accuracy. In this paper, we propose a coordinated beamforming framework for a reconfigurable intelligent surface (RIS)-empowered ISAC system, where the active precoding at the dual-functional base station (DFBS) and the passive beamforming at the RIS are jointly optimized to provide communication services for legitimate unmanned aerial vehicles (UAVs) while sensing the unauthorized UAVs. The sum-rate of all legitimate UAVs are maximized, while satisfying the radar sensing signal-to-noise ratio requirements, the transmit power constraints, and the reflection coefficients of the RIS. To address the inherent non-convexity from coupled variables, we propose a low-complexity algorithm integrating fractional programming with alternating optimization, featuring convergence guarantees. Numerical results demonstrate that the proposed algorithm achieves higher data rate compared to disjoint optimization benchmarks. This underscores RIS's pivotal role in harmonizing communication and target sensing functionalities for low-altitude networks.

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High-Fidelity Functional Ultrasound Reconstruction via A Visual Auto-Regressive Framework

Functional ultrasound (fUS) imaging provides exceptional spatiotemporal resolution for neurovascular mapping, yet its practical application is significantly hampered by critical challenges. Foremost among these are data scarcity, arising from ethical considerations and signal degradation through the cranium, which collectively limit dataset diversity and compromise the fairness of downstream machine learning models.

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ConnectomeDiffuser: Generative AI Enables Brain Network Construction from Diffusion Tensor Imaging

Brain network analysis plays a crucial role in diagnosing and monitoring neurodegenerative disorders such as Alzheimer's disease (AD). Existing approaches for constructing structural brain networks from diffusion tensor imaging (DTI) often rely on specialized toolkits that suffer from inherent limitations: operator subjectivity, labor-intensive workflows, and restricted capacity to capture complex topological features and disease-specific biomarkers. To overcome these challenges and advance computational neuroimaging instrumentation, ConnectomeDiffuser is proposed as a novel diffusion-based framework for automated end-to-end brain network construction from DTI. The proposed model combines three key components: (1) a Template Network that extracts topological features from 3D DTI scans using Riemannian geometric principles, (2) a diffusion model that generates comprehensive brain networks with enhanced topological fidelity, and (3) a Graph Convolutional Network classifier that incorporates disease-specific markers to improve diagnostic accuracy. ConnectomeDiffuser demonstrates superior performance by capturing a broader range of structural connectivity and pathology-related information, enabling more sensitive analysis of individual variations in brain networks. Experimental validation on datasets representing two distinct neurodegenerative conditions demonstrates significant performance improvements over other brain network methods. This work contributes to the advancement of instrumentation in the context of neurological disorders, providing clinicians and researchers with a robust, generalizable measurement framework that facilitates more accurate diagnosis, deeper mechanistic understanding, and improved therapeutic monitoring of neurodegenerative diseases such as AD.

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Flexible and Explainable Graph Analysis for EEG-based Alzheimer's Disease Classification

Alzheimer's Disease is a progressive neurological disorder that is one of the most common forms of dementia. It leads to a decline in memory, reasoning ability, and behavior, especially in older people. The cause of Alzheimer's Disease is still under exploration and there is no all-inclusive theory that can explain the pathologies in each individual patient. Nevertheless, early intervention has been found to be effective in managing symptoms and slowing down the disease's progression. Recent research has utilized electroencephalography (EEG) data to identify biomarkers that distinguish Alzheimer's Disease patients from healthy individuals. Prior studies have used various machine learning methods, including deep learning and graph neural networks, to examine electroencephalography-based signals for identifying Alzheimer's Disease patients. In our research, we proposed a Flexible and Explainable Gated Graph Convolutional Network (GGCN) with Multi-Objective Tree-Structured Parzen Estimator (MOTPE) hyperparameter tuning. This provides a flexible solution that efficiently identifies the optimal number of GGCN blocks to achieve the optimized precision, specificity, and recall outcomes, as well as the optimized area under the Receiver Operating Characteristic (AUC). Our findings demonstrated a high efficacy with an over 0.9 Receiver Operating Characteristic score, alongside precision, specificity, and recall scores in distinguishing health control with Alzheimer's Disease patients in Moderate to Severe Dementia using the power spectrum density (PSD) of electroencephalography signals across various frequency bands. Moreover, our research enhanced the interpretability of the embedded adjacency matrices, revealing connectivity differences in frontal and parietal brain regions between Alzheimer's patients and healthy individuals.

cs.LG↗

CATD: Unified Representation Learning for EEG-to-fMRI Cross-Modal Generation

Multi-modal neuroimaging analysis is crucial for a comprehensive understanding of brain function and pathology, as it allows for the integration of different imaging techniques, thus overcoming the limitations of individual modalities. However, the high costs and limited availability of certain modalities pose significant challenges. To address these issues, this paper proposes the Condition-Aligned Temporal Diffusion (CATD) framework for end-to-end cross-modal synthesis of neuroimaging, enabling the generation of functional magnetic resonance imaging (fMRI)-detected Blood Oxygen Level Dependent (BOLD) signals from more accessible Electroencephalography (EEG) signals. By constructing Conditionally Aligned Block (CAB), heterogeneous neuroimages are aligned into a latent space, achieving a unified representation that provides the foundation for cross-modal transformation in neuroimaging. The combination with the constructed Dynamic Time-Frequency Segmentation (DTFS) module also enables the use of EEG signals to improve the temporal resolution of BOLD signals, thus augmenting the capture of the dynamic details of the brain. Experimental validation demonstrates that the framework improves the accuracy of brain activity state prediction by 9.13% (reaching 69.8%), enhances the diagnostic accuracy of brain disorders by 4.10% (reaching 99.55%), effectively identifies abnormal brain regions, enhancing the temporal resolution of BOLD signals. The proposed framework establishes a new paradigm for cross-modal synthesis of neuroimaging by unifying heterogeneous neuroimaging data into a latent representation space, showing promise in medical applications such as improving Parkinson's disease prediction and identifying abnormal brain regions.

cs.CV↗

SG-GAN: Fine Stereoscopic-Aware Generation for 3D Brain Point Cloud Up-sampling from a Single Image

In minimally-invasive brain surgeries with indirect and narrow operating environments, 3D brain reconstruction is crucial. However, as requirements of accuracy for some new minimally-invasive surgeries (such as brain-computer interface surgery) are higher and higher, the outputs of conventional 3D reconstruction, such as point cloud (PC), are facing the challenges that sample points are too sparse and the precision is insufficient. On the other hand, there is a scarcity of high-density point cloud datasets, which makes it challenging to train models for direct reconstruction of high-density brain point clouds. In this work, a novel model named stereoscopic-aware graph generative adversarial network (SG-GAN) with two stages is proposed to generate fine high-density PC conditioned on a single image. The Stage-I GAN sketches the primitive shape and basic structure of the organ based on the given image, yielding Stage-I point clouds. The Stage-II GAN takes the results from Stage-I and generates high-density point clouds with detailed features. The Stage-II GAN is capable of correcting defects and restoring the detailed features of the region of interest (ROI) through the up-sampling process. Furthermore, a parameter-free-attention-based free-transforming module is developed to learn the efficient features of input, while upholding a promising performance. Comparing with the existing methods, the SG-GAN model shows superior performance in terms of visual quality, objective measurements, and performance in classification, as demonstrated by comprehensive results measured by several evaluation metrics including PC-to-PC error and Chamfer distance.

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BG-GAN: Generative AI Enable Representing Brain Structure-Function Connections for Alzheimer's Disease

The relationship between brain structure and function is critical for revealing the pathogenesis of brain disorders, including Alzheimer's disease (AD). However, mapping brain structure to function connections is a very challenging task. In this work, a bidirectional graph generative adversarial network (BG-GAN) is proposed to represent brain structure-function connections. Specifically, by designing a module incorporating inner graph convolution network (InnerGCN), the generators of BG-GAN can employ features of direct and indirect brain regions to learn the mapping function between the structural domain and the functional domain. Besides, a new module named Balancer is designed to counterpoise the optimization between generators and discriminators. By introducing the Balancer into BG-GAN, both the structural generator and functional generator can not only alleviate the issue of mode collapse but also learn complementarity of structural and functional features. Experimental results using the Alzheimer's Disease Neuroimaging Initiative (ADNI) dataset show that both generated structure and function connections can improve the identification accuracy of AD. The experimental findings suggest that the relationship between brain structure and function is not a complete one-to-one correspondence. They also suggest that brain structure is the basis of brain function, and the strong structural connections are majorly accompanied by strong functional connections.

cs.AI↗

Generative AI Enables EEG Super-Resolution via Spatio-Temporal Adaptive Diffusion Learning

Electroencephalogram (EEG) technology, particularly high-density EEG (HD EEG) devices, is widely used in fields such as neuroscience. HD EEG devices improve the spatial resolution of EEG by placing more electrodes on the scalp, which meet the requirements of clinical diagnostic applications such as epilepsy focus localization. However, this technique faces challenges, such as high acquisition costs and limited usage scenarios. In this paper, spatio-temporal adaptive diffusion models (STAD) are proposed to pioneer the use of diffusion models for achieving spatial SR reconstruction from low-resolution (LR, 64 channels or fewer) EEG to high-resolution (HR, 256 channels) EEG. Specifically, a spatio-temporal condition module is designed to extract the spatio-temporal features of LR EEG, which are then used as conditional inputs to direct the reverse denoising process. Additionally, a multi-scale Transformer denoising module is constructed to leverage multi-scale convolution blocks and cross-attention-based diffusion Transformer blocks for conditional guidance to generate subject-adaptive SR EEG. Experimental results demonstrate that the STAD significantly enhances the spatial resolution of LR EEG and quantitatively outperforms existing methods. Furthermore, STAD demonstrate their value by applying synthetic SR EEG to classification and source localization tasks, indicating their potential to substantially boost the spatial resolution of EEG.

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Underwater Image Restoration Through a Prior Guided Hybrid Sense Approach and Extensive Benchmark Analysis

Underwater imaging grapples with challenges from light-water interactions, leading to color distortions and reduced clarity. In response to these challenges, we propose a novel Color Balance Prior \textbf{Guided} \textbf{Hyb}rid \textbf{Sens}e \textbf{U}nderwater \textbf{I}mage \textbf{R}estoration framework (\textbf{GuidedHybSensUIR}). This framework operates on multiple scales, employing the proposed \textbf{Detail Restorer} module to restore low-level detailed features at finer scales and utilizing the proposed \textbf{Feature Contextualizer} module to capture long-range contextual relations of high-level general features at a broader scale. The hybridization of these different scales of sensing results effectively addresses color casts and restores blurry details. In order to effectively point out the evolutionary direction for the model, we propose a novel \textbf{Color Balance Prior} as a strong guide in the feature contextualization step and as a weak guide in the final decoding phase. We construct a comprehensive benchmark using paired training data from three real-world underwater datasets and evaluate on six test sets, including three paired and three unpaired, sourced from four real-world underwater datasets. Subsequently, we tested 14 traditional and retrained 23 deep learning existing underwater image restoration methods on this benchmark, obtaining metric results for each approach. This effort aims to furnish a valuable benchmarking dataset for standard basis for comparison. The extensive experiment results demonstrate that our method outperforms 37 other state-of-the-art methods overall on various benchmark datasets and metrics, despite not achieving the best results in certain individual cases. The code and dataset are available at \href{https://github.com/CXH-Research/GuidedHybSensUIR}{https://github.com/CXH-Research/GuidedHybSensUIR}.

cs.CV↗

Retrieval-Augmented Generation for Mobile Edge Computing via Large Language Model

The rapid evolution of mobile edge computing (MEC) has introduced significant challenges in optimizing resource allocation in highly dynamic wireless communication systems, in which task offloading decisions should be made in real-time. However, existing resource allocation strategies cannot well adapt to the dynamic and heterogeneous characteristics of MEC systems, since they are short of scalability, context-awareness, and interpretability. To address these issues, this paper proposes a novel retrieval-augmented generation (RAG) method to improve the performance of MEC systems. Specifically, a latency minimization problem is first proposed to jointly optimize the data offloading ratio, transmit power allocation, and computing resource allocation. Then, an LLM-enabled information-retrieval mechanism is proposed to solve the problem efficiently. Extensive experiments across multi-user, multi-task, and highly dynamic offloading scenarios show that the proposed method consistently reduces latency compared to several DL-based approaches, achieving 57% improvement under varying user computing ability, 86% with different servers, 30% under distinct transmit powers, and 42% for varying data volumes. These results show the effectiveness of LLM-driven solutions to solve the resource allocation problems in MEC systems.

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Dual-Hybrid Attention Network for Specular Highlight Removal

Specular highlight removal plays a pivotal role in multimedia applications, as it enhances the quality and interpretability of images and videos, ultimately improving the performance of downstream tasks such as content-based retrieval, object recognition, and scene understanding. Despite significant advances in deep learning-based methods, current state-of-the-art approaches often rely on additional priors or supervision, limiting their practicality and generalization capability. In this paper, we propose the Dual-Hybrid Attention Network for Specular Highlight Removal (DHAN-SHR), an end-to-end network that introduces novel hybrid attention mechanisms to effectively capture and process information across different scales and domains without relying on additional priors or supervision. DHAN-SHR consists of two key components: the Adaptive Local Hybrid-Domain Dual Attention Transformer (L-HD-DAT) and the Adaptive Global Dual Attention Transformer (G-DAT). The L-HD-DAT captures local inter-channel and inter-pixel dependencies while incorporating spectral domain features, enabling the network to effectively model the complex interactions between specular highlights and the underlying surface properties. The G-DAT models global inter-channel relationships and long-distance pixel dependencies, allowing the network to propagate contextual information across the entire image and generate more coherent and consistent highlight-free results. To evaluate the performance of DHAN-SHR and facilitate future research in this area, we compile a large-scale benchmark dataset comprising a diverse range of images with varying levels of specular highlights. Through extensive experiments, we demonstrate that DHAN-SHR outperforms 18 state-of-the-art methods both quantitatively and qualitatively, setting a new standard for specular highlight removal in multimedia applications.

cs.CV↗

A New Brain Network Construction Paradigm for Brain Disorder via Diffusion-based Graph Contrastive Learning

Brain network analysis plays an increasingly important role in studying brain function and the exploring of disease mechanisms. However, existing brain network construction tools have some limitations, including dependency on empirical users, weak consistency in repeated experiments and time-consuming processes. In this work, a diffusion-based brain network pipeline, DGCL is designed for end-to-end construction of brain networks. Initially, the brain region-aware module (BRAM) precisely determines the spatial locations of brain regions by the diffusion process, avoiding subjective parameter selection. Subsequently, DGCL employs graph contrastive learning to optimize brain connections by eliminating individual differences in redundant connections unrelated to diseases, thereby enhancing the consistency of brain networks within the same group. Finally, the node-graph contrastive loss and classification loss jointly constrain the learning process of the model to obtain the reconstructed brain network, which is then used to analyze important brain connections. Validation on two datasets, ADNI and ABIDE, demonstrates that DGCL surpasses traditional methods and other deep learning models in predicting disease development stages. Significantly, the proposed model improves the efficiency and generalization of brain network construction. In summary, the proposed DGCL can be served as a universal brain network construction scheme, which can effectively identify important brain connections through generative paradigms and has the potential to provide disease interpretability support for neuroscience research.

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