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Shuying Shen

Publications and source records attributed to Shuying Shen.

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Incremental effects for continuous exposures

Causal inference problems often involve continuous treatments, such as dose, duration, or frequency. However, identifying and estimating standard dose-response estimands requires that everyone has some chance of receiving any level of the exposure (i.e., positivity). To avoid this assumption, we consider stochastic interventions based on exponentially tilting the treatment distribution by some parameter $δ$ (an incremental effect); this increases or decreases the likelihood a unit receives a given treatment level. We derive the efficient influence function and semiparametric efficiency bound for these incremental effects under continuous exposures. We then show estimation depends on the size of the tilt, as measured by $δ$. In particular, we derive new minimax lower bounds illustrating how the best possible root mean squared error scales with an effective sample size of $n / δ$, instead of $n$. Further, we establish new convergence rates and bounds on the bias of double machine learning-style estimators. Our novel analysis gives a better dependence on $δ$ compared to standard analyses by using mixed supremum and $L_2$ norms. Finally, we define a "reflected" exponential tilt around any interior point and show that taking $δ\to \infty$ yields a new estimator of the dose-response curve across the treatment support.

stat.ME

Sensitivity analysis for incremental effects, with application to a study of victimization & offending

Sensitivity analysis for unmeasured confounding under incremental propensity score interventions remains relatively underdeveloped. Incremental interventions define stochastic treatment regimes by multiplying the odds of treatment, offering a flexible framework for causal effect estimation. To study incremental effects when there are unobserved confounders, we adopt Rosenbaum's sensitivity model in single time point settings, and propose a doubly robust estimator for the resulting effect bounds. The bound estimators are asymptotically normal under mild conditions on nuisance function estimation. We show that incremental effect bounds can be narrower or wider than those for mean potential outcomes, and that the bounds must lie between the expected minimum and maximum of the conditional bounds on E(Y^0|X) and E(Y^1|X). For time-varying treatments, we consider the marginal sensitivity model. Although sharp bounds for incremental effects are identifiable from longitudinal data under this model, practical estimators have not yet been established; we discuss this challenge and provide partial results toward implementation. Finally, we apply our methods to study the effect of victimization on subsequent offending using data from the National Longitudinal Study of Adolescent to Adult Health (Add Health), illustrating the robustness of our findings in an empirical setting.

stat.ME