arXiv subjects

Sicheng Xing

Publications and source records attributed to Sicheng Xing.

3 recordsLinked to original sources

arXiv2024

Orbit symmetry breaking in MXene implements enhanced soft bioelectronic implants

Bioelectronic implants with soft mechanics, biocompatibility, and excellent electrical performance enable biomedical implants to record electrophysiological signals and execute interventions within internal organs, promising to revolutionize the diagnosing, monitoring, and treatment of various pathological conditions. However, challenges remain in improving excessive impedance at the bioelectronic-tissue interface and thus the efficacy of electrophysiological signaling and intervention. Here, we devise orbit symmetry breaking in MXene (a low-cost scalability, biocompatible, and conductive 2D layered material, that we refer to as OBXene), that exhibits low bioelectronic-tissue impedance, originating from the out-of-plane charge transfer. Furthermore, the Schottky-induced piezoelectricity stemming from the asymmetric orbital configuration of OBXene facilitates interlayered charge transport in the device. In this study, we report an OBXene-based cardiac patch applied on the left ventricular epicardium of both rodent and porcine models to enable spatiotemporal epicardium mapping and pacing, while coupling the wireless and battery-free operation for long-term real-time recording and closed-loop stimulation.

physics.app-ph↗

arXiv2024

Symmetry engineering in 2D bioelectronics facilitating augmented biosensing interfaces

Symmetry lies at the heart of 2D bioelectronics, determining material properties at the fundamental level. Breaking the symmetry allows emergent functionalities and effects. However, symmetry modulation in 2D bioelectronics and the resultant applications have been largely overlooked. Here we devise an oxidized architectural MXene, referred as OXene, that couples orbit symmetric breaking with inverse symmetric breaking to entitle the optimized interfacial impedance and Schottky-induced piezoelectric effects. The resulting OXene validates applications ranging from microelectrode arrays, gait analysis, active transistor matrix, and wireless signaling transmission, which enables highly-fidelity signal transmission and reconfigurable logic gates. Further OXene interfaces are investigated in both rodent and porcine myocardium, featuring high-quality and spatiotemporally resolved physiological recordings, while accurate differentiated predictions, enabled via various machine learning pipelines.

physics.app-ph↗

arXiv2023

Collabs: A Flexible and Performant CRDT Collaboration Framework

A collaboration framework is a distributed system that serves as the data layer for a collaborative app. Conflict-free Replicated Data Types (CRDTs) are a promising theoretical technique for implementing collaboration frameworks. However, existing frameworks are inflexible: they are often one-off implementations of research papers or only permit a restricted set of CRDT semantics, and they do not allow app-specific optimizations. Until now, there was no general framework that lets programmers mix, match, and modify CRDTs. We solve this with Collabs, a CRDT-based collaboration framework that lets programmers implement their own CRDTs, either from-scratch or by composing existing building blocks. Collabs prioritizes both semantic flexibility and performance flexibility: it allows arbitrary app-specific CRDT behaviors and optimizations, while still providing strong eventual consistency. We demonstrate Collabs's capabilities and programming model with example apps and CRDT implementations. We then show that a collaborative rich-text editor using Collabs's built-in CRDTs can scale to over 100 simultaneous users, unlike existing CRDT frameworks and Google Docs. Collabs also has lower end-to-end latency and server CPU usage than a popular Operational Transformation framework, with acceptable CRDT metadata overhead.

cs.DC↗