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Sihyeon Park

Publications and source records attributed to Sihyeon Park.

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MedSNIP: Building and Benchmarking Snippet-Level Granularity for Medical Fact Verification

A medical claim's correctness often depends not on the claim alone, but on the clinical structure around it. A claim may require a lab reference range, a causal or conditional link, or patient-specific details to be judged correctly, and atom-level decomposition can fragment these dependencies, leaving the verifier with clinically incomplete claims. We reformulate medical fact-checking around snippet-level verification, where clause-grouped units preserve local clinical structure. We introduce MedSNIP-Bench, a human-annotated benchmark for snippet-level medical fact verification, and MedSNIP, an automatic snippet-generation pipeline. MedSNIP-Bench covers 276 consumer-health and clinical-vignette responses, segmented into 2,524 snippets with dual in-general and in-patient-context labels and six structural pattern codes. MedSNIP is evaluated against human snippet boundaries on MedSNIP-Bench and then used to generate snippet-level units for external corpora. Across MedSNIP-Bench, HealthFC, and MedHallu, snippet-level verification preserves or improves false-class F1, with gains concentrated where answers are long enough to fragment and where the verifier is strong enough to exploit the recovered structure. The largest merge-pattern gain is on causal-conditional clinical chains. It also reduces verifier calls by 24-73%, though the saving survives end-to-end only when decomposition is cheap, which an open-weight decomposer makes possible at no loss of chunking fidelity.

cs.CL

Rationale-Guided Retrieval Augmented Generation for Medical Question Answering

Large language models (LLM) hold significant potential for applications in biomedicine, but they struggle with hallucinations and outdated knowledge. While retrieval-augmented generation (RAG) is generally employed to address these issues, it also has its own set of challenges: (1) LLMs are vulnerable to irrelevant or incorrect context, (2) medical queries are often not well-targeted for helpful information, and (3) retrievers are prone to bias toward the specific source corpus they were trained on. In this study, we present RAG$^2$ (RAtionale-Guided RAG), a new framework for enhancing the reliability of RAG in biomedical contexts. RAG$^2$ incorporates three key innovations: a small filtering model trained on perplexity-based labels of rationales, which selectively augments informative snippets of documents while filtering out distractors; LLM-generated rationales as queries to improve the utility of retrieved snippets; a structure designed to retrieve snippets evenly from a comprehensive set of four biomedical corpora, effectively mitigating retriever bias. Our experiments demonstrate that RAG$^2$ improves the state-of-the-art LLMs of varying sizes, with improvements of up to 6.1\%, and it outperforms the previous best medical RAG model by up to 5.6\% across three medical question-answering benchmarks. Our code is available at https://github.com/dmis-lab/RAG2.

cs.CL

Learning from Negative Samples in Biomedical Generative Entity Linking

Generative models have become widely used in biomedical entity linking (BioEL) due to their excellent performance and efficient memory usage. However, these models are usually trained only with positive samples, i.e., entities that match the input mention's identifier, and do not explicitly learn from hard negative samples, which are entities that look similar but have different meanings. To address this limitation, we introduce ANGEL (Learning from Negative Samples in Biomedical Generative Entity Linking), the first framework that trains generative BioEL models using negative samples. Specifically, a generative model is initially trained to generate positive entity names from the knowledge base for given input entities. Subsequently, both correct and incorrect outputs are gathered from the model's top-k predictions. Finally, the model is updated to prioritize the correct predictions through preference optimization. Our models outperform the previous best baseline models by up to an average top-1 accuracy of 1.4% on five benchmarks. When incorporating our framework into pre-training, the performance improvement increases further to 1.7%, demonstrating its effectiveness in both the pre-training and fine-tuning stages. The code and model weights are available at https://github.com/dmis-lab/ANGEL.

cs.CL

Small Language Models Learn Enhanced Reasoning Skills from Medical Textbooks

While recent advancements in commercial large language models (LM) have shown promising results in medical tasks, their closed-source nature poses significant privacy and security concerns, hindering their widespread use in the medical field. Despite efforts to create open-source models, their limited parameters often result in insufficient multi-step reasoning capabilities required for solving complex medical problems. To address this, we introduce Meerkat, a new family of medical AI systems ranging from 7 to 70 billion parameters. The models were trained using our new synthetic dataset consisting of high-quality chain-of-thought reasoning paths sourced from 18 medical textbooks, along with diverse instruction-following datasets. Our systems achieved remarkable accuracy across six medical benchmarks, surpassing the previous best models such as MediTron and BioMistral, and GPT-3.5 by a large margin. Notably, Meerkat-7B surpassed the passing threshold of the United States Medical Licensing Examination (USMLE) for the first time for a 7B-parameter model, while Meerkat-70B outperformed GPT-4 by an average of 1.3%. Additionally, Meerkat-70B correctly diagnosed 21 out of 38 complex clinical cases, outperforming humans' 13.8 and closely matching GPT-4's 21.8. Our systems offered more detailed free-form responses to clinical queries compared to existing small models, approaching the performance level of large commercial models. This significantly narrows the performance gap with large LMs, showcasing its effectiveness in addressing complex medical challenges.

cs.CL