arXiv subjects

Silvia Conforto

Publications and source records attributed to Silvia Conforto.

3 recordsLinked to original sources

arXiv2018

An Adaptive Cluster-based Filtering Framework for Speckle Reduction of OCT Skin Images

Optical coherence tomography (OCT) has become a favorable device in the Dermatology discipline due to its moderate resolution and penetration depth. OCT images however contain a grainy pattern, called speckle, due to the use of a broadband source in the configuration of OCT. So far, a variety of filtering (de-speckling) techniques is introduced to reduce speckle in OCT images. Most of these methods are generic and can be applied to OCT images of different tissues. The ambition of this work is to provide a de-speckling framework specialized for filtering skin tissues for the community to utilize, adapt or build upon. In this paper, we present an adaptive cluster-based filtering framework, optimized for speckle reduction of OCT skin images. In this framework, by considering the layered structure of skin, first the OCT skin images are segmented into differentiable layers utilizing clustering algorithms, and then each cluster is de-speckled individually using adaptive filtering techniques. In this study, hierarchical clustering algorithm and adaptive Wiener filtering technique are utilized to develop the framework. The proposed method is tested on optical solid phantoms with predetermined optical properties. The method is also tested on healthy human skin images. The results show that the proposed cluster-based filtering method can effectively reduce the speckle and increase the signal-to-noise ratio and contrast while preserving the edges in the image. The proposed cluster-based filtering framework enables researchers to develop unsupervised learning solutions for de-speckling OCT skin images using adaptive filtering methods, or extend the framework to new applications.

cs.CV↗

arXiv2017

A Learnable Despeckling Framework for Optical Coherence Tomography Images

Optical coherence tomography (OCT) is a prevalent, interferometric, high-resolution imaging method with broad biomedical applications. Nonetheless, OCT images suffer from an artifact, called speckle which degrades the image quality. Digital filters offer an opportunity for image improvement in clinical OCT devices where hardware modification to enhance images is expensive. To reduce speckle, a wide variety of digital filters have been proposed, selecting the most appropriate filter for each OCT image/image set is a challenging decision. To tackle this challenge, we propose an expandable learnable despeckling framework, we called LDF. LDF decides which speckle reduction algorithm is most effective on a given image by learning a figure of merit (FOM) as a single quantitative image assessment measure. The architecture of LDF includes two main parts: (i) an autoencoder neural network, (ii) filter classifier. The autoencoder learns the figure of merit based on the quality assessment measures obtained from the OCT image including.Subsequently, the filter classifier identifies the most efficient filter from the following categories: (a) sliding window filters including median, mean, and symmetric nearest neighborhood, (b) adaptive statistical based filters including Wiener, homomorphic Lee, and Kuwahara, and, (c) edge preserved patch or pixel correlation based filters including non-local mean, total variation, and block matching 3D filtering.

physics.med-ph↗

arXiv2017

Universal in vivo Textural Model for Human Skin based on Optical Coherence Tomograms

Currently, diagnosis of skin diseases is based primarily on visual pattern recognition skills and expertise of the physician observing the lesion. Even though dermatologists are trained to recognize patterns of morphology, it is still a subjective visual assessment. Tools for automated pattern recognition can provide objective information to support clinical decision-making. Noninvasive skin imaging techniques provide complementary information to the clinician. In recent years, optical coherence tomography has become a powerful skin imaging technique. According to specific functional needs, skin architecture varies across different parts of the body, as do the textural characteristics in OCT images. There is, therefore, a critical need to systematically analyze OCT images from different body sites, to identify their significant qualitative and quantitative differences. Sixty-three optical and textural features extracted from OCT images of healthy and diseased skin are analyzed and in conjunction with decision-theoretic approaches used to create computational models of the diseases. We demonstrate that these models provide objective information to the clinician to assist in the diagnosis of abnormalities of cutaneous microstructure, and hence, aid in the determination of treatment. Specifically, we demonstrate the performance of this methodology on differentiating basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) from healthy tissue.

q-bio.TO↗