arXiv subjects

Sinian Zhang

Publications and source records attributed to Sinian Zhang.

5 recordsLinked to original sources

arXiv2026

Aligning Language Models with Selective Prediction

Large language models (LLMs) are increasingly deployed as critical decision-making components in high-stakes real-world AI systems, rendering LLM reliability a foremost practical concern. In this paper, we focus on enhancing LLM reliability through selective prediction (SP), a strategy that allows an LLM to only predict for inputs where it is likely to be correct (i.e., coverage) and hence reduce the error rate (i.e., risk) on that portion of inputs -- flagging the remaining inputs for future human discretion. In other words, SP improves LLM reliability by balancing the risk-coverage trade-off and enabling seamless human-AI collaboration. To integrate SP into LLMs, we focus on the LLM post-training alignment stage and propose to align LLMs with SP performance metrics, in contrast with existing LLM alignment methods that focus primarily on correctness or calibration metrics. Specifically, we propose a novel alignment framework, Reinforcement Learning for Selection Reward (RLSR), which targets the area under the risk-coverage curve (AURC) -- a popular SP performance metric -- as its alignment objective. RLSR achieves substantially better risk-coverage trade-off compared to multiple alignment baselines on both in-domain and out-of-domain tasks.

cs.LG↗

arXiv2025

Generalized Linear Markov Decision Process

Offline reinforcement learning for longitudinal studies often faces two linked challenges: rewards may be binary or bounded, and reward observations may be available only for a subset of trajectories or time points even when the corresponding state-action-next-state histories are available. Linear Markov decision process methods are tractable because Bellman backups remain linear, but they require linear rewards and do not indicate how transition-only observations should be used. We introduce GRASP-MDP, Generalized Reward And Semi-supervised Pessimism for Markov Decision Processes, a reward-transition separated framework addressing both issues through one Bellman decomposition. It preserves linear transition dynamics while modeling reward means through generalized linear models. Although this breaks the usual linear Bellman form, the backup remains explicit as a nonlinear reward component plus a linear continuation component, yielding a nonlinear-plus-linear Bellman-complete class. In the resulting recursion, observed rewards estimate the generalized reward component, while all available transitions estimate the continuation component. The resulting pessimistic value iteration controls the two estimation errors separately without reward imputation. Finite-sample guarantees show that transition-only observations reduce transition-estimation error while reward uncertainty remains governed by observed rewards. Simulations and a multiple sclerosis electronic health record application illustrate the empirical benefit of retaining transition-only observations.

stat.ML↗

arXiv2025

DrKGC: Dynamic Subgraph Retrieval-Augmented LLMs for Knowledge Graph Completion across General and Biomedical Domains

Knowledge graph completion (KGC) aims to predict missing triples in knowledge graphs (KGs) by leveraging existing triples and textual information. Recently, generative large language models (LLMs) have been increasingly employed for graph tasks. However, current approaches typically encode graph context in textual form, which fails to fully exploit the potential of LLMs for perceiving and reasoning about graph structures. To address this limitation, we propose DrKGC (Dynamic Subgraph Retrieval-Augmented LLMs for Knowledge Graph Completion). DrKGC employs a flexible lightweight model training strategy to learn structural embeddings and logical rules within the KG. It then leverages a novel bottom-up graph retrieval method to extract a subgraph for each query guided by the learned rules. Finally, a graph convolutional network (GCN) adapter uses the retrieved subgraph to enhance the structural embeddings, which are then integrated into the prompt for effective LLM fine-tuning. Experimental results on two general domain benchmark datasets and two biomedical datasets demonstrate the superior performance of DrKGC. Furthermore, a realistic case study in the biomedical domain highlights its interpretability and practical utility.

cs.AI↗

arXiv2025

Wasserstein Transfer Learning

Transfer learning is a powerful paradigm for leveraging knowledge from source domains to enhance learning in a target domain. However, traditional transfer learning approaches often focus on scalar or multivariate data within Euclidean spaces, limiting their applicability to complex data structures such as probability distributions. To address this limitation, we introduce a novel transfer learning framework for regression models whose outputs are probability distributions residing in the Wasserstein space. When the informative subset of transferable source domains is known, we propose an estimator with provable asymptotic convergence rates, quantifying the impact of domain similarity on transfer efficiency. For cases where the informative subset is unknown, we develop a data-driven transfer learning procedure designed to mitigate negative transfer. The proposed methods are supported by rigorous theoretical analysis and are validated through extensive simulations and real-world applications. The code is available at https://github.com/h7nian/WaTL

cs.LG↗

arXiv2024

The Wreaths of KHAN: Uniform Graph Feature Selection with False Discovery Rate Control

Graphical models find numerous applications in biology, chemistry, sociology, neuroscience, etc. While substantial progress has been made in graph estimation, it remains largely unexplored how to select significant graph signals with uncertainty assessment, especially those graph features related to topological structures including cycles (i.e., wreaths), cliques, hubs, etc. These features play a vital role in protein substructure analysis, drug molecular design, and brain network connectivity analysis. To fill the gap, we propose a novel inferential framework for general high dimensional graphical models to select graph features with false discovery rate controlled. Our method is based on the maximum of $p$-values from single edges that comprise the topological feature of interest, thus is able to detect weak signals. Moreover, we introduce the $K$-dimensional persistent Homology Adaptive selectioN (KHAN) algorithm to select all the homological features within $K$ dimensions with the uniform control of the false discovery rate over continuous filtration levels. The KHAN method applies a novel discrete Gram-Schmidt algorithm to select statistically significant generators from the homology group. We apply the structural screening method to identify the important residues of the SARS-CoV-2 spike protein during the binding process to the ACE2 receptors. We score the residues for all domains in the spike protein by the $p$-value weighted filtration level in the network persistent homology for the closed, partially open, and open states and identify the residues crucial for protein conformational changes and thus being potential targets for inhibition.

math.ST↗