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Siyuan Ma

Publications and source records attributed to Siyuan Ma.

At least 19 recordsLinked to original sources
arXiv2026

FWBC-VLA: Force-Aware Whole-Body Compensation for Contact-Rich Loco-Manipulation

Contact-rich loco-manipulation requires a bridge between semantic action generation and physical interaction control. Existing Vision-language-action (VLA) models generate task-level actions from visual and linguistic observations, but cannot interpret the physical interactions induced by those actions. While the whole-body control (WBC) policy can stabilize the robot, it cannot distinguish task-relevant interaction forces from forces induced by external disturbances during manipulation. Although force/torque sensors provide direct measurements of physical interactions, retrofitting them entails additional hardware costs and substantial integration effort, particularly for platforms not designed with sensor integration in mind. To address this problem, we propose FWBC-VLA, a force-aware framework that bridges task-level VLA action generation and low-level whole-body compensation control for wheeled-legged robots. First, we introduce HSR-Force, a sensorless residual-torque estimator for inferring contact strength and its temporal variation. These contact estimates are then encoded as tokens and injected into the VLA action expert during action decoding, enabling the policy to perceive contact onset, sustained loading, and release. For loco-manipulation tasks, all parameters of the pretrained VLA backbone are fine-tuned on our WL\&Arm Dataset, which comprises more than 5,000 episodes. Moreover, the robot's proprioceptive state, the Jacobian-derived body-frame force estimate, and the estimated contact state are jointly fed into a compensation generator to produce corrective actions. The manipulation-centric actions are subsequently combined with the corrective actions and passed to the WBC policy for execution. Real-world experiments on whiteboard wiping and door opening with a door closer demonstrate the effectiveness of our FWBC-VLA in contact-rich loco-manipulation.

cs.RO↗
arXiv2026

RegimeFormer: A Large Protein Model of Global Perturbation Regimes

Protein language models organize sequence and structure at scale, but a global representation of how proteins respond to mutation remains lacking. We present RegimeFormer, a large protein perturbation model coupled to RegimeAtlas, constructed by harmonizing and indexing 202,556,313 non-redundant protein sequences across the tree of life. A diversity-preserving one-million-protein subset provides the high-resolution training and inference layer, with 995,995 proteins yielding residue-level summaries across 407,048,356 residues and substitution-specific predictions available on demand. Across experimental deep mutational scanning, molecular benchmarks, structural confidence and evolutionary constraint, RegimeFormer identifies reproducible protein-level perturbation regimes that organize residue fragility, adaptability and predictive uncertainty. Regime conditioning improves substitution-specific prediction, with the largest relative gains under unseen-protein, unseen-family and low-homology evaluation. RegimeFormer-derived molecular priors further improve downstream transcriptomic and drug-response modelling. Together, RegimeFormer and RegimeAtlas provide a scalable framework for mapping, predicting and querying protein perturbation landscapes across global sequence space.

q-bio.QM↗
arXiv2026

ForeTime-VLA: Causal Future-Token Distillation from a World Action Model for Conveyor-Belt Manipulation

Manipulating moving objects requires a policy to anticipate contact events, yet vision-language-action (VLA) policies are commonly fine-tuned from the current observation alone. World action models (WAMs) learn predictive dynamics, but running a video-scale teacher or explicitly imagining future frames at deployment is costly. We introduce ForeTime-VLA, a dense pi0.5 policy that distills a future-aware, action-equivalent representation from a frozen Fast-WAM-derived teacher while remaining causal at inference. Offline, current and future video latents are compressed into a whitened 64-D target. Online, an eight-frame history encoder predicts this target together with manipulation phase and normalized time-to-transition. Four future tokens and one phase token condition the VLM prefix, while the predicted future and transition horizon condition the action expert. Training retains the original flow-matching action target and adds cosine, relational geometry, phase, time-to-transition, and action-equivalence objectives. On a deduplicated conveyor-belt dataset, we compare 40k-step checkpoints on 768 matched windows per split. Test MAE decreases from 0.134119 to 0.130593 (2.63%; paired-bootstrap 95% CI: 0.82-4.48% improvement), and test L2 decreases by 3.02%, at a 2.46-2.93% latency cost. In quantitative real-robot evaluation, ForeTime-VLA achieves 81.1% stationary and 58.9% slow-moving grasp success, exceeding the next-best reference by 12.2 and 22.2 percentage points, respectively. Across three belt speeds, it completes 44/90 grasps versus 23/90 for pi0.5, including 11/30 versus 2/30 at fast speed. The agreement between offline orientation gains and reduced real-robot contact-pose failures supports causal future-token distillation as an effective way to improve dynamic manipulation without deploying the world-model teacher.

cs.AI↗
arXiv2026

DECOWAM: Decoupled Whole-Body World-Action Model for Legged Mobile Manipulation

Mobile manipulation requires a robot to predict how locomotion and arm motion jointly alter future observations and control. Existing world-action models, developed largely for fixed-base platforms, do not explicitly distinguish camera ego-motion from base and arm actions. Here we introduce DECOWAM, a whole-body world-action model that separates these factors through dedicated conditional interfaces. DECOWAM freezes an adapted FastWAM backbone and trains residual adapters, an action-equivalent future bottleneck distilled from privileged observations, adversarially separated base and arm latents, and base-velocity conditioning for video prediction. We further introduce ARMDOG, a real-robot dataset that synchronizes video, whole-body state and action, and language. On a fixed replay protocol, DECOWAM improved both future-video and action prediction over FastWAM, reducing action MSE by 21.7% with 25.95M trainable adaptation parameters. Across 79 closed-loop trials per method, it achieved the highest observed whole-body coordination and base-displacement robustness among the compared systems, while task completion remained comparable to the strongest baseline. These results show that embodiment-aware factorization can support parameter-efficient joint visual prediction and whole-body control under moving viewpoints.

cs.AI↗
arXiv2026

A cross-modal generative model for incomplete and degraded prostate MRI with multicentre clinical validation

Missing or degraded sequences can limit prostate multiparametric MRI. We developed MSCNet, a sequence-conditioned cross-modal generative framework for reconstructing unavailable contrasts and restoring degraded acquisitions. Across ten completion tasks, task-specific MSCNet achieved mean structural similarity of 0.818 versus 0.798 for the strongest task-matched comparators; matched-capacity analyses showed larger differences in lesion fidelity and boundary preservation. In a blinded 1,000-case reader study, overall image quality met the prespecified non-inferiority criterion for DWI, ADC and T2W completion, but not T1W. In a separate 200-case diagnostic assessment, AUCs for clinically significant cancer were 0.860 with acquired images, 0.841 with MSCNet and 0.797 with baseline-generated images. A locked 186-case three-hospital cohort supported multicentre transportability. These retrospective results support quality-controlled cross-modal reconstruction as an adjunct to acquired prostate MRI.

eess.IV↗
arXiv2026

FutureBridge: Token Selection Beyond Local Preference in Collaborative Decoding

Token-level collaboration allows a large language model (LLM) to assist a small language model (SLM) when their predictions diverge. Existing methods either use LLM-generated intervention tokens or rank candidates with the LLM's next-token probabilities. Both rely on the LLM's local preference, even though an LLM-selected token may be difficult for the SLM to build on. We present FutureBridge, which ranks joint LLM-SLM token candidates according to how well they support the SLM's subsequent reasoning. During training, an answer-verified LLM trajectory supplies a fixed shared future, and a frozen SLM evaluates every candidate under this common context. The resulting counterfactual scores supervise a lightweight token reranker that observes only the current state and candidate token. At inference, FutureBridge uses the LLM only to expand the candidate pool, selects one token, and returns generation to the SLM without generating or appending a future suffix. Across five mathematical reasoning benchmarks, FutureBridge improves the Qwen3-1.7B SLM's Math Avg. by 35.1% relative to greedy SLM decoding. These results indicate that token selection benefits from modeling whether the receiving SLM can use each candidate to continue reasoning, rather than relying on the LLM's local preference alone.

cs.CL↗
arXiv2026

Analytical and Bootstrap Confidence Intervals of Double Machine Learning: Simulation studies and an application to rural-urban difference in obesity prevalence

Double Machine Learning (DML) is a popular approach for treatment effect estimation in various settings, which allows a wide range of flexible machine learning methods to be used for nuisance parameter estimation while preserving valid inference. In practice, however, applied researchers must choose among many machine learning algorithms for nuisance models, and the impact of this choice on the variance estimation of DML is not well characterized. We conduct a comprehensive simulation study to compare the coverage probability of DML confidence intervals across different machine learning algorithms. In this study, we compare (1) analytical confidence intervals derived by DML theory versus (2) bootstrap confidence interval. We use a set of learners including ordinary least squares, LASSO, Random Forest, LightGBM, and Neural Networks under different data generation settings. We evaluate the performance across difference settings by bias, confidence interval width, and most importantly, coverage probability. Our results show substantial variability in coverage performance across analytical and bootstrap confidence intervals, highlighting that learner choice plays a critical role in reliable DML inference. Surprisingly, we find that in many settings, when sample size increases, the coverage probability of both DML analytical and bootstrap confidence interval decreases. We further investigate coverage probabilities using a real dataset on rural urban differences among U.S. counties. The real data analysis discovers that (1) the model performance still varies by the learner choices and (2) greater rurality has a statistically significant increasing effect on county level obesity prevalence.

stat.ML↗
arXiv2026

Text as Partial Constraint: Core-Residual Alignment for Robust Vision-Language Learning

Vision-language alignment powers open-vocabulary recognition, retrieval, and LVLM grounding, yet natural captions are often underspecified, making similarity brittle and overly confident under paraphrase and omitted details. We aim to learn representations whose matching is stable across caption views and whose confidence reflects how strongly text constrains an image. We propose Text as Partial Constraint (TPC), a core-residual alignment framework that treats multi-view captions as incomplete supervision. It distills a consensus semantic core as the alignment target, learns a single-view core predictor for standard inference with one query, and explicitly discourages vision-language similarity from depending on the orthogonal unsaid residual. An uncertainty-aware contrastive objective further softens alignment when caption views disagree, reducing overconfident updates under weak language constraints. Across zero-shot recognition and adversarial robustness, TPC achieves 81.42/64.05 Top-1 clean/robust accuracy on ImageNet and 76.19/52.03 on an Avg-14 transfer suite, while improving LVLM transfer with 85.16 POPE F1 and 59.57 OKVQA accuracy under an LLaVA-1.5-7B stack. These results suggest that modeling text as a partial constraint is a practical and principled route to more reliable vision-language representations under underspecified language supervision.

cs.CV↗
arXiv2026

AGVBench: A Reliability-Oriented Benchmark of Data Augmentation for Vein Recognition

Vein recognition is a secure biometric technology often constrained by limited annotated data and imaging variations. While data augmentation mitigates this, strategies designed for natural images may disrupt the fine-grained topology and textures essential for identity discrimination. We present AGVBench, which evaluates 30 representative augmentation strategies on five public palm- and finger-vein datasets with seven backbone architectures, covering classic CNNs, vision transformers, and vein-specific recognition models. Our results show that multi-image mixing methods (e.g., MixUp, PuzzleMix, StarMixup) generally provide the strongest recognition performance. However, they are often poorly calibrated and vulnerable to adversarial perturbations, revealing a clear inconsistency between clean accuracy and adversarial security. We also find that severe geometric transformations frequently degrade recognition, which is potentially due to feature misalignment or spatial cropping, and that augmentation effectiveness varies across palm and finger vein datasets. These findings prove that accuracy-centric evaluation is insufficient for biometric augmentation. AGVBench provides standardized protocols to support reproducible research and guide the design of reliable, secure, and robust vein recognition systems. Our codebase is available at https://github.com/Advance-VeinTech-Innovators/AGVBench.

cs.CV↗
arXiv2026

Knowledge-augmented Agentic AI for Mental Health Medication Information Seeking

Patients increasingly seek medication information online, yet safety knowledge for psychiatric drugs is split between regulatory adverse-event records, which are authoritative but abstract, and patient narratives, which are experience-near but unvalidated. Integrating them without conflating evidence and anecdote is especially consequential in psychiatry, where poorly contextualised information can amplify fear, nocebo responses, and non-adherence. Here we develop a provenance-aware, knowledge-graph-based multi-agent framework unifying 466,525 Reddit posts, 60,782 WebMD reviews, and twenty years of U.S. FDA Adverse Event Reporting System records for nine antidepressants. A large-language-model entity-recognition pipeline benchmarked against physician annotations reached highest F1 scores of 0.969 for medications and 0.973 for conditions. The two community platforms were far more concordant with each other (overlap up to a Jaccard similarity of 0.905) than with regulatory reports, indicating that patient-generated data form a partly independent safety signal. For sertraline, many adverse events appeared in community sources hundreds of days before the corresponding FDA date. A Neo4j knowledge graph grounded in ATC-N, ICD-10, and MedDRA vocabularies preserves provenance, keeping every claim traceable and regulatory facts distinct from patient experience. These results establish source-aware integration as a route to more auditable psychiatric medication information, with usefulness and patient benefit to be tested prospectively.

cs.AI↗
arXiv2026

Attention-Spectrum Regularization for Replay-Free Continual Multimodal LLMs

Multimodal large language models (MLLMs) are increasingly required to adapt to non-stationary streams of visual domains, question types, and user instructions, yet continual fine-tuning often causes severe forgetting of previously acquired multimodal skills. Existing continual vision-language methods mainly preserve outputs, replay data or pseudo-data, regularize embedding geometry, or allocate task-specific parameters, but they provide limited control over how internal cross-modal attention patterns supporting old skills drift during adaptation. We propose Attention-Spectrum Regularization (ASR), a replay-free continual learning framework that preserves skill-conditioned structures of cross-modal attention. ASR treats cross-attention maps as two-dimensional signals, summarizes their scale and directional properties into compact spectral statistics, and stores only skill-wise prototype distributions instead of replaying past image-question pairs, generated pseudo-examples, or old-stage teacher snapshots. In later stages, a phase-invariant spectral regularizer constrains harmful drift of these prototypes while allowing instance-level attention to adapt to new tasks. We provide theoretical analysis showing that skill-conditioned spectral drift controls forgetting under a spectral sufficiency assumption, and that Fourier power spectra are stable to spatial translations and bounded perturbations. Experiments on continual VQA and multimodal instruction-tuning benchmarks, including VQA v2, VQACL, CLT-VQA, CoIN, and UCIT, show that ASR consistently improves final performance and reduces forgetting over strong replay-, regularization-, and adapter-based baselines. Preserving skill-level attention structure is an effective and lightweight mechanism for continual MLLMs. Code is available at https://github.com/Creative-zcx/attention-spectrum-replay

cs.CV↗
arXiv2026

Agent-Assisted Side-Channel Attacks on Non-Prefix KV Cache in RAG

Modern Large Language Model (LLM) serving engines increasingly rely on Retrieval-Augmented Generation (RAG) and non-prefix Key-Value (KV) cache fusion to accelerate long-context, multi-tenant inference. While existing KV cache side-channel attacks require strict linear prefix alignment--rendering them ineffective against real-world RAG queries that contain unique, user-specific private prefixes--we uncover a critical class of structural vulnerabilities inherent to chunk-aware memory scheduling. We demonstrate that the deterministic micro-architectural mechanisms used to align and fuse disjoint memory chunks inadvertently leak a continuous "Step-Wave" timing signature. Exploiting this physical observation, we introduce SpliceLeak, the first end-to-end side-channel attack targeting non-prefix KV cache fusion. SpliceLeak executes a systematic two-phase privacy breach: it first structurally fingerprints the exact length of hidden private prompts, and subsequently manipulates boundary collisions to extract exact semantic content token-by-token. Extensive evaluations on production-grade frameworks (vLLM integrated with LMCache) demonstrate that SpliceLeak achieves up to a 100% extraction success rate in bounded-entropy scenarios. Driven by a deterministic +104 ms hardware latency void, the attack requires as few as 63 requests per token, piercing through realistic continuous batching noise. To resolve the inherent conflict between memory deduplication and security, we propose SpliceDefense, a bipartite mitigation framework consisting of Quantized Chunk Padding (QCP) and Constant-Time Boundary Fusion (CTBF). Our evaluations confirm that SpliceDefense effectively flattens the side-channel signal (Delta TTFT ~ 0) with negligible throughput overhead, preserving the critical benefits of global cache sharing.

cs.CR↗
arXiv2026

Teaching agentic AI to generalize expert diagnostic reasoning in rare diseases

Rare disease diagnosis depends on expert reasoning that is scarce and difficult to transfer. Large language models rank the correct disease first in only 35.4% of benchmark cases and often rely on learned phenotype-disease associations rather than reusable diagnostic reasoning strategies. We developed liteOdyssey through Policy Iteration with Human Feedback, a process in which model failures and expert corrections are iteratively consolidated into a clinician-gated, natural-language policy executed by a language model. Across 1,243 public benchmark cases spanning 722 rare diseases, liteOdyssey ranked the correct disease first in 59.3% of cases versus 26.5% without the policy, with comparable gains in cases involving diseases excluded from policy development. The same policy transferred across model families and sizes without retraining. Adaptation of the policy to the Undiagnosed Diseases Network (UDN) improved diagnostic accuracy among 515 UDN patients, with gains confirmed by blinded physician adjudication. These results show that expert reasoning can be externalized into an inspectable and revisable natural-language policy that generalizes across rare diseases, transfers across model backbones, and adapts to a real-world patient cohort.

cs.AI↗
arXiv2026

LLM-as-a-Judge in Healthcare: A Scoping Analysis of Applications, Methods, and Human Alignment

Large language models (LLMs) are increasingly deployed across healthcare applications, including clinical documentation, diagnostic reasoning, medicine recommendation, and medical education. Their outputs are largely unstructured clinical text, which is difficult to reliably evaluate at scale. LLM-as-a-Judge, in which an LLM evaluates another system's output against task-specific criteria, offers a scalable alternative and is increasingly used in clinical evaluation, yet its validity in healthcare remains underexamined. Existing reviews focus on general-purpose LLM evaluation or on risk framework, rather than systematically characterizing how LLM-as-a-Judge is applied in healthcare and how well their judgments align with human experts. We therefore conduct a PRISMA-guided comprehensive review of LLM-as-a-Judge applications in healthcare, searching five databases for studies published between January 2023 and February 2026. After screening 541 records, 134 studies meet the eligibility and are coded by health scenario, judge configuration, technical approach, and validation design. LLM-as-a-Judge is concentrated in clinical decision support, clinical natural language processing (NLP), medical knowledge and question answering (QA), and medical communication. OpenAI models are the most frequently used judges, and prompt engineering appears in nearly all studies, with ensemble, multi-agent, and retrieval-augmented designs as common extensions. Among studies reporting human validation, LLM judges often show moderate to strong alignment with expert judgments, although reliability varies substantially across tasks. Overall, this review positions LLM-as-a-Judge as a promising framework for scalable healthcare AI evaluation, while emphasizing that its clinical value depends on model design and rigorous validation.

cs.CY↗
arXiv2026

BOOKAGENT: Orchestrating Safety-Aware Visual Narratives via Multi-Agent Cognitive Calibration

Recent advancements in Large Generative Models (LGMs) have revolutionized multi-modal generation. However, generating illustrated storybooks remains an open challenge, where prior works mainly decompose this task into separate stages, and thus, holistic multi-modal grounding remains limited. Besides, while safety alignment is studied for text- or image-only generation, existing works rarely integrate child-specific safety constraints into narrative planning and sequence-level multi-modal verification. To address these limitations, we propose BookAgent, a safety-aware multi-agent collaboration framework designed for high-quality, safety-aware visual narratives. Different from prior story visualization models that assume a fixed storyline sequence, BookAgent targets end-to-end storybook synthesis from a user draft by jointly planning, scripting, illustrating, and globally repairing inconsistencies. To ensure precise multi-modal grounding, BookAgent dynamically calibrates page-level alignment between textual scripts and visual layouts. Furthermore, BookAgent calibrates holistic consistency from the temporal dimension, by verifying-then-rectifying global inconsistencies in character identity and storytelling logic. Extensive experiments demonstrate that BookAgent significantly outperforms current methods in narrative coherence, visual consistency, and safety compliance, offering a robust paradigm for reliable agents in complex multi-modal creation. The implementation will be publicly released at https://github.com/bogao-code/BookAgent/tree/main.

cs.CV↗
arXiv2026

A comparative study on power delivery aspects of compute-in/near-memory approaches using DRAM

Compute-in-memory (PIM) mitigates the memory wall by performing computation within memory, reducing data movement and improving energy efficiency. DRAM-based PIM is particularly attractive due to its high density, mature manufacturing ecosystem, and compatibility with existing systems. Recent works exploit multiple levels of the DRAM hierarchy - including subarrays, banks, and 3D-stacked organizations - to enable in-memory computation using mechanisms such as multi-row activation, row-buffer operations, and near-bank compute units. However, these approaches introduce non-traditional current demand patterns that challenge the power delivery network (PDN). This paper surveys PDN challenges in DRAM-based PIM systems and proposes a unified taxonomy that characterizes PIM-induced current behavior along temporal (burst vs. sustained) and spatial (localized vs. distributed) dimensions. Using this framework, we analyze how representative PIM techniques stress the PDN through bursty activations, multi-row concurrency, and large-scale parallel execution, leading to voltage droop, IR drop, and thermal hotspots. We further discuss DRAM-specific mitigation strategies leveraging existing architectural and circuit-level mechanisms, including timing constraints, memory controller scheduling, data placement, and bank- and vault-level power management. This survey highlights the importance of PDN-aware design for scalable and reliable DRAM-based PIM systems and outlines key future research directions.

cs.AR↗
arXiv2026

The Latent Space: Foundation, Evolution, Mechanism, Ability, and Outlook

Latent space is rapidly emerging as a native substrate for language-based models. While modern systems are still commonly understood through explicit token-level generation, an increasing body of work shows that many critical internal processes are more naturally carried out in continuous latent space than in human-readable verbal traces. This shift is driven by the structural limitations of explicit-space computation, including linguistic redundancy, discretization bottlenecks, sequential inefficiency, and semantic loss. This survey aims to provide a unified and up-to-date landscape of latent space in language-based models. We organize the survey into five sequential perspectives: Foundation, Evolution, Mechanism, Ability, and Outlook. We begin by delineating the scope of latent space, distinguishing it from explicit or verbal space and from the latent spaces commonly studied in generative visual models. We then trace the field's evolution from early exploratory efforts to the current large-scale expansion. To organize the technical landscape, we examine existing work through the complementary lenses of mechanism and ability. From the perspective of Mechanism, we identify four major lines of development: Architecture, Representation, Computation, and Optimization. From the perspective of Ability, we show how latent space supports a broad capability spectrum spanning Reasoning, Planning, Modeling, Perception, Memory, Collaboration, and Embodiment. Beyond consolidation, we discuss the key open challenges, and outline promising directions for future research. We hope this survey serves not only as a reference for existing work, but also as a foundation for understanding latent space as a general computational and systems paradigm for next-generation intelligence.

cs.AI↗
arXiv2026

CoT2-Meta: Budgeted Metacognitive Control for Test-Time Reasoning

Recent test-time reasoning methods improve performance by generating more candidate chains or searching over larger reasoning trees, but they typically lack explicit control over when to expand, what to prune, how to repair, and when to abstain. We introduce CoT2-Meta, a training-free metacognitive reasoning framework that combines object-level chain-of-thought generation with meta-level control over partial reasoning trajectories. The framework integrates four components: strategy-conditioned thought generation, tree-structured search, an online process oracle for step-level reasoning evaluation, and a meta-controller that allocates computation through expansion, pruning, repair, stopping, and fallback decisions. Under matched inference budgets, CoT2-Meta consistently outperforms strong single-path, sampling-based, and search-based baselines, including ReST-MCTS. On the default backbone, it achieves 92.8 EM on MATH, 90.4 accuracy on GPQA, 98.65 EM on GSM8K, 75.8 accuracy on BBEH, 85.6 accuracy on MMMU-Pro, and 48.8 accuracy on HLE, with gains over the strongest non-CoT2-Meta baseline of +3.6, +5.2, +1.15, +2.0, +4.3, and +4.3 points, respectively. Beyond these core results, the framework remains effective across a broader 15-benchmark suite spanning knowledge and QA, multi-hop reasoning, coding, and out-of-distribution evaluation. Additional analyses show better compute scaling, improved calibration, stronger selective prediction, targeted repair behavior, and consistent gains across backbone families. These results suggest that explicit metacognitive control is a practical design principle for reliable and compute-efficient test-time reasoning systems.

cs.AI↗