An AI-Based Multi-Stage Approach for Androgenetic Alopecia Assessment from Low-Magnification Scalp Images
Androgenetic alopecia (AGA) is characterized by patterned follicular miniaturization, increased single-hair follicular units, and altered hair-shaft diameter. We present an automated quantitative scalp-analysis and clinical decision-support framework combining FU localization, ordinal visible-shaft counting, calibrated shaft-width estimation, regional aggregation, and an interpretable rule layer. The clinical cohort comprised 243 patients (127 AGA, 116 non-AGA), while the computer-vision experiments used 160 expert-annotated patients, 2,400 trichoscopic images, and approximately 158,000 FU annotations. Under patientdisjoint evaluation, YOLOv8m achieved test mAP@0.5=0.920 and recall=0.860; EfficientNet-B5 with a support-map channel achieved 87.0% expert-box count accuracy (macro F1=0.85). A separate 500-image set was processed end-to-end with detector-generated boxes, yielding MAE of 6.56 for follicle detection and 16.59 for follicle classification relative to human-expert annotations. The system is intended to assist, rather than replace, dermatologist interpretation.