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Sophie Shermer

Publications and source records attributed to Sophie Shermer.

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Robustness of Energy Landscape Control to Dephasing

As shown in previous work, in some cases closed quantum systems exhibit a non-conventional trade-off in performance and robustness in the sense that controllers with the highest fidelity can also provide the best robustness to parameter uncertainty. As the dephasing induced by the interaction of the system with the environment guides the evolution to a more classically mixed state, it is worth investigating what effect the introduction of dephasing has on the relationship between performance and robustness. In this paper we analyze the robustness of the fidelity error, as measured by the logarithmic sensitivity function, to dephasing processes. We show that introduction of dephasing as a perturbation to the nominal unitary dynamics requires a modification of the log-sensitivity formulation used to measure robustness about an uncertain parameter with non-zero nominal value used in previous work. We consider controllers optimized for a number of target objectives ranging from fidelity under coherent evolution to fidelity under dephasing dynamics to determine the extent to which optimizing for a specific regime has desirable effects in terms of robustness. Our analysis is based on two independent computations of the log-sensitivity: a statistical Monte Carlo approach and an analytic calculation. We show that despite the different log sensitivity calculations employed in this study, both demonstrate that the log-sensitivity of the fidelity error to dephasing results in a conventional trade-off between performance and robustness.

quant-ph

Design and Characterisation of Tissue-Mimicking Gel Phantoms for Diffusion Kurtosis Imaging

Purpose: The aim of this work was to create tissue-mimicking gel phantoms appropriate for diffusion kurtosis imaging (DKI) for quality assurance, protocol optimization and sequence development. Methods: A range of agar, agarose and polyvinyl alcohol phantoms with concentrations ranging from 1.0% to 3.5%, 0.5% to 3.0% and 10% to 20%, respectively, and up to 3 g of glass microspheres per 100 ml were created. Diffusion coefficients, excess kurtosis values and relaxation rates were experimentally determined. Results: The kurtosis values for the plain gels ranged from 0.05 with 95% confidence interval (CI) of $(0.029, 0.071)$ to $0.216(0.185, 0.246)$, well below the kurtosis values reported in the literature for various tissues. The addition of glass microspheres increased the kurtosis of the gels with values up to $0.523(0.465, 0.581)$ observed for gels with the highest concentration of microspheres. Repeat scans of some of the gels after more than six months of storage at room temperature indicate changes in the diffusion parameters of less than 10%. The addition of the glass microspheres reduces the apparent diffusion coefficients (ADCs) and increases the longitudinal and transverse relaxation rates but the values remain comparable to those for plain gels and tissue, with ADCs observed ranging from $818(585, 1053) \times 10^{-6}$ mm$^2$/s to $2257(2118, 2296) \times 10^{-6}$ mm$^2$/s, and R1 values ranging from $0.34(0.32, 0.35)$ 1/s to $0.51(0.50, 0.52)$ 1/s, and R2 values ranging from $9.69(9.34, 10.04)$ 1/s to $33.07(27.10, 39.04)$ 1/s. Conclusions: Glass microspheres can be used to effectively modify diffusion properties of gel phantoms and achieve a range of kurtosis values comparable to those reported for a variety of tissues.

physics.med-ph