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Srinivasan Parthasarathy

Publications and source records attributed to Srinivasan Parthasarathy.

At least 55 records · Page 3Linked to original sources

Fairness-aware Summarization for Justified Decision-Making

In consequential domains such as recidivism prediction, facility inspection, and benefit assignment, it's important for individuals to know the decision-relevant information for the model's prediction. In addition, predictions should be fair both in terms of the outcome and the justification of the outcome. In other words, decision-relevant features should provide sufficient information for the predicted outcome and should be independent of the membership of individuals in protected groups such as race and gender. In this work, we focus on the problem of (un)fairness in the justification of the text-based neural models. We tie the explanatory power of the model to fairness in the outcome and propose a fairness-aware summarization mechanism to detect and counteract the bias in such models. Given a potentially biased natural language explanation for a decision, we use a multi-task neural model and an attribution mechanism based on integrated gradients to extract high-utility and low-bias justifications in form of a summary. The extracted summary is then used for training a model to make decisions for individuals. Results on several real world datasets suggest that our method drastically limits the demographic leakage in the input (fairness in justification) while moderately enhancing the fairness in the outcome. Our model is also effective in detecting and counteracting several types of data poisoning attacks that synthesize race-coded reasoning or irrelevant justifications.

cs.AI↗

M2: Mixed Models with Preferences, Popularities and Transitions for Next-Basket Recommendation

Next-basket recommendation considers the problem of recommending a set of items into the next basket that users will purchase as a whole. In this paper, we develop a novel mixed model with preferences, popularities and transitions (M2) for the next-basket recommendation. This method models three important factors in next-basket generation process: 1) users' general preferences, 2) items' global popularities and 3) transition patterns among items. Unlike existing recurrent neural network-based approaches, M2 does not use the complicated networks to model the transitions among items, or generate embeddings for users. Instead, it has a simple encoder-decoder based approach (ed-Trans) to better model the transition patterns among items. We compared M2 with different combinations of the factors with 5 state-of-the-art next-basket recommendation methods on 4 public benchmark datasets in recommending the first, second and third next basket. Our experimental results demonstrate that M2 significantly outperforms the state-of-the-art methods on all the datasets in all the tasks, with an improvement of up to 22.1%. In addition, our ablation study demonstrates that the ed-Trans is more effective than recurrent neural networks in terms of the recommendation performance. We also have a thorough discussion on various experimental protocols and evaluation metrics for next-basket recommendation evaluation.

cs.LG↗

A Deep Generative Model for Molecule Optimization via One Fragment Modification

Molecule optimization is a critical step in drug development to improve desired properties of drug candidates through chemical modification. We developed a novel deep generative model Modof over molecular graphs for molecule optimization. Modof modifies a given molecule through the prediction of a single site of disconnection at the molecule and the removal and/or addition of fragments at that site. A pipeline of multiple, identical Modof models is implemented into Modof-pipe to modify an input molecule at multiple disconnection sites. Here we show that Modof-pipe is able to retain major molecular scaffolds, allow controls over intermediate optimization steps and better constrain molecule similarities. Modof-pipe outperforms the state-of-the-art methods on benchmark datasets: without molecular similarity constraints, Modof-pipe achieves 81.2% improvement in octanol-water partition coefficient penalized by synthetic accessibility and ring size; and 51.2%, 25.6% and 9.2% improvement if the optimized molecules are at least 0.2, 0.4 and 0.6 similar to those before optimization, respectively. Modof-pipe is further enhanced into Modof-pipem to allow modifying one molecule to multiple optimized ones. Modof-pipem achieves additional performance improvement as at least 17.8% better than Modof-pipe.

cs.LG↗

Evaluating Biomedical BERT Models for Vocabulary Alignment at Scale in the UMLS Metathesaurus

The current UMLS (Unified Medical Language System) Metathesaurus construction process for integrating over 200 biomedical source vocabularies is expensive and error-prone as it relies on the lexical algorithms and human editors for deciding if the two biomedical terms are synonymous. Recent advances in Natural Language Processing such as Transformer models like BERT and its biomedical variants with contextualized word embeddings have achieved state-of-the-art (SOTA) performance on downstream tasks. We aim to validate if these approaches using the BERT models can actually outperform the existing approaches for predicting synonymy in the UMLS Metathesaurus. In the existing Siamese Networks with LSTM and BioWordVec embeddings, we replace the BioWordVec embeddings with the biomedical BERT embeddings extracted from each BERT model using different ways of extraction. In the Transformer architecture, we evaluate the use of the different biomedical BERT models that have been pre-trained using different datasets and tasks. Given the SOTA performance of these BERT models for other downstream tasks, our experiments yield surprisingly interesting results: (1) in both model architectures, the approaches employing these biomedical BERT-based models do not outperform the existing approaches using Siamese Network with BioWordVec embeddings for the UMLS synonymy prediction task, (2) the original BioBERT large model that has not been pre-trained with the UMLS outperforms the SapBERT models that have been pre-trained with the UMLS, and (3) using the Siamese Networks yields better performance for synonymy prediction when compared to using the biomedical BERT models.

cs.CL↗

Semi-Supervised Deep Learning for Multiplex Networks

Multiplex networks are complex graph structures in which a set of entities are connected to each other via multiple types of relations, each relation representing a distinct layer. Such graphs are used to investigate many complex biological, social, and technological systems. In this work, we present a novel semi-supervised approach for structure-aware representation learning on multiplex networks. Our approach relies on maximizing the mutual information between local node-wise patch representations and label correlated structure-aware global graph representations to model the nodes and cluster structures jointly. Specifically, it leverages a novel cluster-aware, node-contextualized global graph summary generation strategy for effective joint-modeling of node and cluster representations across the layers of a multiplex network. Empirically, we demonstrate that the proposed architecture outperforms state-of-the-art methods in a range of tasks: classification, clustering, visualization, and similarity search on seven real-world multiplex networks for various experiment settings.

cs.LG↗

Privacy Policy Question Answering Assistant: A Query-Guided Extractive Summarization Approach

Existing work on making privacy policies accessible has explored new presentation forms such as color-coding based on the risk factors or summarization to assist users with conscious agreement. To facilitate a more personalized interaction with the policies, in this work, we propose an automated privacy policy question answering assistant that extracts a summary in response to the input user query. This is a challenging task because users articulate their privacy-related questions in a very different language than the legal language of the policy, making it difficult for the system to understand their inquiry. Moreover, existing annotated data in this domain are limited. We address these problems by paraphrasing to bring the style and language of the user's question closer to the language of privacy policies. Our content scoring module uses the existing in-domain data to find relevant information in the policy and incorporates it in a summary. Our pipeline is able to find an answer for 89% of the user queries in the privacyQA dataset.

cs.CL↗

SYSML: StYlometry with Structure and Multitask Learning: Implications for Darknet Forum Migrant Analysis

Darknet market forums are frequently used to exchange illegal goods and services between parties who use encryption to conceal their identities. The Tor network is used to host these markets, which guarantees additional anonymization from IP and location tracking, making it challenging to link across malicious users using multiple accounts (sybils). Additionally, users migrate to new forums when one is closed, making it difficult to link users across multiple forums. We develop a novel stylometry-based multitask learning approach for natural language and interaction modeling using graph embeddings to construct low-dimensional representations of short episodes of user activity for authorship attribution. We provide a comprehensive evaluation of our methods across four different darknet forums demonstrating its efficacy over the state-of-the-art, with a lift of up to 2.5X on Mean Retrieval Rank and 2X on Recall@10.

cs.CL↗

A Tight Bound for Stochastic Submodular Cover

We show that the Adaptive Greedy algorithm of Golovin and Krause (2011) achieves an approximation bound of $(\ln (Q/η)+1)$ for Stochastic Submodular Cover: here $Q$ is the "goal value" and $η$ is the smallest non-zero marginal increase in utility deliverable by an item. (For integer-valued utility functions, we show a bound of $H(Q)$, where $H(Q)$ is the $Q^{th}$ Harmonic number.) Although this bound was claimed by Golovin and Krause in the original version of their paper, the proof was later shown to be incorrect by Nan and Saligrama (2017). The subsequent corrected proof of Golovin and Krause (2017) gives a quadratic bound of $(\ln(Q/η) + 1)^2$. Other previous bounds for the problem are $56(\ln(Q/η) + 1)$, implied by work of Im et al. (2016) on a related problem, and $k(\ln (Q/η)+1)$, due to Deshpande et al. (2016) and Hellerstein and Kletenik (2018), where $k$ is the number of states. Our bound generalizes the well-known $(\ln~m + 1)$ approximation bound on the greedy algorithm for the classical Set Cover problem, where $m$ is the size of the ground set.

cs.DS↗

A Machine Learning Model for Nowcasting Epidemic Incidence

Due to delay in reporting, the daily national and statewide COVID-19 incidence counts are often unreliable and need to be estimated from recent data. This process is known in economics as nowcasting. We describe in this paper a simple random forest statistical model for nowcasting the COVID - 19 daily new infection counts based on historic data along with a set of simple covariates, such as the currently reported infection counts, day of the week, and time since first reporting. We apply the model to adjust the daily infection counts in Ohio, and show that the predictions from this simple data-driven method compare favorably both in quality and computational burden to those obtained from the state-of-the-art hierarchical Bayesian model employing a complex statistical algorithm.

q-bio.QM↗

eDarkTrends: Harnessing Social Media Trends in Substance use disorders for Opioid Listings on Cryptomarket

Opioid and substance misuse is rampant in the United States today, with the phenomenon known as the opioid crisis. The relationship between substance use and mental health has been extensively studied, with one possible relationship being substance misuse causes poor mental health. However, the lack of evidence on the relationship has resulted in opioids being largely inaccessible through legal means. This study analyzes the substance misuse posts on social media with the opioids being sold through crypto market listings. We use the Drug Abuse Ontology, state-of-the-art deep learning, and BERT-based models to generate sentiment and emotion for the social media posts to understand user perception on social media by investigating questions such as, which synthetic opioids people are optimistic, neutral, or negative about or what kind of drugs induced fear and sorrow or what kind of drugs people love or thankful about or which drug people think negatively about or which opioids cause little to no sentimental reaction. We also perform topic analysis associated with the generated sentiments and emotions to understand which topics correlate with people's responses to various drugs. Our findings can help shape policy to help isolate opioid use cases where timely intervention may be required to prevent adverse consequences, prevent overdose-related deaths, and worsen the epidemic.

cs.AI↗

Driving Style Representation in Convolutional Recurrent Neural Network Model of Driver Identification

Identifying driving styles is the task of analyzing the behavior of drivers in order to capture variations that will serve to discriminate different drivers from each other. This task has become a prerequisite for a variety of applications, including usage-based insurance, driver coaching, driver action prediction, and even in designing autonomous vehicles; because driving style encodes essential information needed by these applications. In this paper, we present a deep-neural-network architecture, we term D-CRNN, for building high-fidelity representations for driving style, that combine the power of convolutional neural networks (CNN) and recurrent neural networks (RNN). Using CNN, we capture semantic patterns of driver behavior from trajectories (such as a turn or a braking event). We then find temporal dependencies between these semantic patterns using RNN to encode driving style. We demonstrate the effectiveness of these techniques for driver identification by learning driving style through extensive experiments conducted on several large, real-world datasets, and comparing the results with the state-of-the-art deep-learning and non-deep-learning solutions. These experiments also demonstrate a useful example of bias removal, by presenting how we preprocess the input data by sampling dissimilar trajectories for each driver to prevent spatial memorization. Finally, this paper presents an analysis of the contribution of different attributes for driver identification; we find that engine RPM, Speed, and Acceleration are the best combination of features.

cs.CV↗

HAM: Hybrid Associations Models for Sequential Recommendation

Sequential recommendation aims to identify and recommend the next few items for a user that the user is most likely to purchase/review, given the user's purchase/rating trajectories. It becomes an effective tool to help users select favorite items from a variety of options. In this manuscript, we developed hybrid associations models (HAM) to generate sequential recommendations using three factors: 1) users' long-term preferences, 2) sequential, high-order and low-order association patterns in the users' most recent purchases/ratings, and 3) synergies among those items. HAM uses simplistic pooling to represent a set of items in the associations, and element-wise product to represent item synergies of arbitrary orders. We compared HAM models with the most recent, state-of-the-art methods on six public benchmark datasets in three different experimental settings. Our experimental results demonstrate that HAM models significantly outperform the state of the art in all the experimental settings, with an improvement as much as 46.6%. In addition, our run-time performance comparison in testing demonstrates that HAM models are much more efficient than the state-of-the-art methods, and are able to achieve significant speedup as much as 139.7 folds.

cs.IR↗

Interpretable Multi-Headed Attention for Abstractive Summarization at Controllable Lengths

Abstractive summarization at controllable lengths is a challenging task in natural language processing. It is even more challenging for domains where limited training data is available or scenarios in which the length of the summary is not known beforehand. At the same time, when it comes to trusting machine-generated summaries, explaining how a summary was constructed in human-understandable terms may be critical. We propose Multi-level Summarizer (MLS), a supervised method to construct abstractive summaries of a text document at controllable lengths. The key enabler of our method is an interpretable multi-headed attention mechanism that computes attention distribution over an input document using an array of timestep independent semantic kernels. Each kernel optimizes a human-interpretable syntactic or semantic property. Exhaustive experiments on two low-resource datasets in the English language show that MLS outperforms strong baselines by up to 14.70% in the METEOR score. Human evaluation of the summaries also suggests that they capture the key concepts of the document at various length-budgets.

cs.CL↗

MILE: A Multi-Level Framework for Scalable Graph Embedding

Recently there has been a surge of interest in designing graph embedding methods. Few, if any, can scale to a large-sized graph with millions of nodes due to both computational complexity and memory requirements. In this paper, we relax this limitation by introducing the MultI-Level Embedding (MILE) framework -- a generic methodology allowing contemporary graph embedding methods to scale to large graphs. MILE repeatedly coarsens the graph into smaller ones using a hybrid matching technique to maintain the backbone structure of the graph. It then applies existing embedding methods on the coarsest graph and refines the embeddings to the original graph through a graph convolution neural network that it learns. The proposed MILE framework is agnostic to the underlying graph embedding techniques and can be applied to many existing graph embedding methods without modifying them. We employ our framework on several popular graph embedding techniques and conduct embedding for real-world graphs. Experimental results on five large-scale datasets demonstrate that MILE significantly boosts the speed (order of magnitude) of graph embedding while generating embeddings of better quality, for the task of node classification. MILE can comfortably scale to a graph with 9 million nodes and 40 million edges, on which existing methods run out of memory or take too long to compute on a modern workstation. Our code and data are publicly available with detailed instructions for adding new base embedding methods: \url{https://github.com/jiongqian/MILE}.

cs.AI↗

DrugDBEmbed : Semantic Queries on Relational Database using Supervised Column Encodings

Traditional relational databases contain a lot of latent semantic information that have largely remained untapped due to the difficulty involved in automatically extracting such information. Recent works have proposed unsupervised machine learning approaches to extract such hidden information by textifying the database columns and then projecting the text tokens onto a fixed dimensional semantic vector space. However, in certain databases, task-specific class labels may be available, which unsupervised approaches are unable to lever in a principled manner. Also, when embeddings are generated at individual token level, then column encoding of multi-token text column has to be computed by taking the average of the vectors of the tokens present in that column for any given row. Such averaging approach may not produce the best semantic vector representation of the multi-token text column, as observed while encoding paragraphs or documents in natural language processing domain. With these shortcomings in mind, we propose a supervised machine learning approach using a Bi-LSTM based sequence encoder to directly generate column encodings for multi-token text columns of the DrugBank database, which contains gold standard drug-drug interaction (DDI) labels. Our text data driven encoding approach achieves very high Accuracy on the supervised DDI prediction task for some columns and we use those supervised column encodings to simulate and evaluate the Analogy SQL queries on relational data to demonstrate the efficacy of our technique.

cs.DB↗

HPRA: Hyperedge Prediction using Resource Allocation

Many real-world systems involve higher-order interactions and thus demand complex models such as hypergraphs. For instance, a research article could have multiple collaborating authors, and therefore the co-authorship network is best represented as a hypergraph. In this work, we focus on the problem of hyperedge prediction. This problem has immense applications in multiple domains, such as predicting new collaborations in social networks, discovering new chemical reactions in metabolic networks, etc. Despite having significant importance, the problem of hyperedge prediction hasn't received adequate attention, mainly because of its inherent complexity. In a graph with $n$ nodes the number of potential edges is $\mathcal{O}(n^{2})$, whereas in a hypergraph, the number of potential hyperedges is $\mathcal{O}(2^{n})$. To avoid searching through such a huge space, current methods restrain the original problem in the following two ways. One class of algorithms assume the hypergraphs to be $k$-uniform. However, many real-world systems are not confined only to have interactions involving $k$ components. Thus, these algorithms are not suitable for many real-world applications. The second class of algorithms requires a candidate set of hyperedges from which the potential hyperedges are chosen. In the absence of domain knowledge, the candidate set can have $\mathcal{O}(2^{n})$ possible hyperedges, which makes this problem intractable. We propose HPRA - Hyperedge Prediction using Resource Allocation, the first of its kind algorithm, which overcomes these issues and predicts hyperedges of any cardinality without using any candidate hyperedge set. HPRA is a similarity-based method working on the principles of the resource allocation process. In addition to recovering missing hyperedges, we demonstrate that HPRA can predict future hyperedges in a wide range of hypergraphs.

cs.SI↗

Understanding Knowledge Gaps in Visual Question Answering: Implications for Gap Identification and Testing

Visual Question Answering (VQA) systems are tasked with answering natural language questions corresponding to a presented image. Traditional VQA datasets typically contain questions related to the spatial information of objects, object attributes, or general scene questions. Recently, researchers have recognized the need to improve the balance of such datasets to reduce the system's dependency on memorized linguistic features and statistical biases, while aiming for enhanced visual understanding. However, it is unclear whether any latent patterns exist to quantify and explain these failures. As an initial step towards better quantifying our understanding of the performance of VQA models, we use a taxonomy of Knowledge Gaps (KGs) to tag questions with one or more types of KGs. Each Knowledge Gap (KG) describes the reasoning abilities needed to arrive at a resolution. After identifying KGs for each question, we examine the skew in the distribution of questions for each KG. We then introduce a targeted question generation model to reduce this skew, which allows us to generate new types of questions for an image. These new questions can be added to existing VQA datasets to increase the diversity of questions and reduce the skew.

cs.CL↗

Graph Embedding on Biomedical Networks: Methods, Applications, and Evaluations

Graph embedding learning that aims to automatically learn low-dimensional node representations, has drawn increasing attention in recent years. To date, most recent graph embedding methods are evaluated on social and information networks and are not comprehensively studied on biomedical networks under systematic experiments and analyses. On the other hand, for a variety of biomedical network analysis tasks, traditional techniques such as matrix factorization (which can be seen as a type of graph embedding methods) have shown promising results, and hence there is a need to systematically evaluate the more recent graph embedding methods (e.g. random walk-based and neural network-based) in terms of their usability and potential to further the state-of-the-art. We select 11 representative graph embedding methods and conduct a systematic comparison on 3 important biomedical link prediction tasks: drug-disease association (DDA) prediction, drug-drug interaction (DDI) prediction, protein-protein interaction (PPI) prediction; and 2 node classification tasks: medical term semantic type classification, protein function prediction. Our experimental results demonstrate that the recent graph embedding methods achieve promising results and deserve more attention in the future biomedical graph analysis. Compared with three state-of-the-art methods for DDAs, DDIs and protein function predictions, the recent graph embedding methods achieve competitive performance without using any biological features and the learned embeddings can be treated as complementary representations for the biological features. By summarizing the experimental results, we provide general guidelines for properly selecting graph embedding methods and setting their hyper-parameters for different biomedical tasks.

cs.LG↗