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Staci A. Hepler

Publications and source records attributed to Staci A. Hepler.

3 recordsLinked to original sources

Combining straight-line and map-based distances to investigate the connection between proximity to healthy foods and disease

Healthy foods are essential for a healthy life, but accessing healthy food can be more challenging for some people than others. This disparity in food access may lead to disparities in well-being, potentially with disproportionate rates of diseases in communities that face more challenges in accessing healthy food (i.e., low-access communities). Identifying low-access, high-risk communities for targeted interventions is a public health priority, but current methods to quantify food access rely on distance measures that are either computationally simple (like the length of the shortest straight-line route) or accurate (like the length of the shortest map-based driving route), but not both. We propose a multiple imputation approach to combine these distance measures, allowing researchers to harness the computational ease of one with the accuracy of the other. The approach incorporates straight-line distances for all neighborhoods and map-based distances for just a subset, offering comparable estimates to the "gold standard" model using map-based distances for all neighborhoods and improved efficiency over the "complete case" model using map-based distances for just the subset. Through the adoption of a measurement error framework, information from the straight-line distances can be leveraged to compute informative placeholders (i.e., impute) for any neighborhoods without map-based distances. Using simulations and data for the Piedmont Triad region of North Carolina, we quantify and compare the associations between two health outcomes (diabetes and obesity) and neighborhood-level access to healthy foods. The imputation procedure also makes it possible to predict the full landscape of food access in an area without requiring map-based measurements for all neighborhoods.

stat.AP

The `Why' behind including `Y' in your imputation model

Missing data is a common challenge when analyzing epidemiological data, and imputation is often used to address this issue. Here, we investigate the scenario where a covariate used in an analysis has missingness and will be imputed. There are recommendations to include the outcome from the analysis model in the imputation model for missing covariates, but it is not necessarily clear if this recommendation always holds and why this is sometimes true. We examine deterministic imputation (i.e., single imputation with fixed values) and stochastic imputation (i.e., single or multiple imputation with random values) methods and their implications for estimating the relationship between the imputed covariate and the outcome. We mathematically demonstrate that including the outcome variable in imputation models is not just a recommendation but a requirement to achieve unbiased results when using stochastic imputation methods. Moreover, we dispel common misconceptions about deterministic imputation models and demonstrate why the outcome should not be included in these models. This paper aims to bridge the gap between imputation in theory and in practice, providing mathematical derivations to explain common statistical recommendations. We offer a better understanding of the considerations involved in imputing missing covariates and emphasize when it is necessary to include the outcome variable in the imputation model.

stat.ME

An integrated abundance model for estimating county-level prevalence of opioid misuse in Ohio

Opioid misuse is a national epidemic and a significant drug related threat to the United States. While the scale of the problem is undeniable, estimates of the local prevalence of opioid misuse are lacking, despite their importance to policy-making and resource allocation. This is due, in part, to the challenge of directly measuring opioid misuse at a local level. In this paper, we develop a Bayesian hierarchical spatio-temporal abundance model that integrates indirect county-level data on opioid-related outcomes with state-level survey estimates on prevalence of opioid misuse to estimate the latent county-level prevalence and counts of people who misuse opioids. A simulation study shows that our integrated model accurately recovers the latent counts and prevalence. We apply our model to county-level surveillance data on opioid overdose deaths and treatment admissions from the state of Ohio. Our proposed framework can be applied to other applications of small area estimation for hard to reach populations, which is a common occurrence with many health conditions such as those related to illicit behaviors.

stat.ME