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Stefan Feuerriegel

Publications and source records attributed to Stefan Feuerriegel.

At least 127 records · Page 7Linked to original sources

Data-Driven Allocation of Preventive Care With Application to Diabetes Mellitus Type II

Problem Definition. Increasing costs of healthcare highlight the importance of effective disease prevention. However, decision models for allocating preventive care are lacking. Methodology/Results. In this paper, we develop a data-driven decision model for determining a cost-effective allocation of preventive treatments to patients at risk. Specifically, we combine counterfactual inference, machine learning, and optimization techniques to build a scalable decision model that can exploit high-dimensional medical data, such as the data found in modern electronic health records. Our decision model is evaluated based on electronic health records from 89,191 prediabetic patients. We compare the allocation of preventive treatments (metformin) prescribed by our data-driven decision model with that of current practice. We find that if our approach is applied to the U.S. population, it can yield annual savings of $1.1 billion. Finally, we analyze the cost-effectiveness under varying budget levels. Managerial Implications. Our work supports decision-making in health management, with the goal of achieving effective disease prevention at lower costs. Importantly, our decision model is generic and can thus be used for effective allocation of preventive care for other preventable diseases.

cs.LG↗

Analyzing the Strategy of Propaganda using Inverse Reinforcement Learning: Evidence from the 2022 Russian Invasion of Ukraine

The 2022 Russian invasion of Ukraine was accompanied by a large-scale, pro-Russian propaganda campaign on social media. However, the strategy behind the dissemination of propaganda has remained unclear, particularly how the online discourse was strategically shaped by the propagandists' community. Here, we analyze the strategy of the Twitter community using an inverse reinforcement learning (IRL) approach. Specifically, IRL allows us to model online behavior as a Markov decision process, where the goal is to infer the underlying reward structure that guides propagandists when interacting with users with a supporting or opposing stance toward the invasion. Thereby, we aim to understand empirically whether and how between-user interactions are strategically used to promote the proliferation of Russian propaganda. For this, we leverage a large-scale dataset with 349,455 posts with pro-Russian propaganda from 132,131 users. We show that bots and humans follow a different strategy: bots respond predominantly to pro-invasion messages, suggesting that they seek to drive virality; while messages indicating opposition primarily elicit responses from humans, suggesting that they tend to engage in critical discussions. To the best of our knowledge, this is the first study analyzing the strategy behind propaganda from the 2022 Russian invasion of Ukraine through the lens of IRL.

cs.SI↗

Interpretable Off-Policy Learning via Hyperbox Search

Personalized treatment decisions have become an integral part of modern medicine. Thereby, the aim is to make treatment decisions based on individual patient characteristics. Numerous methods have been developed for learning such policies from observational data that achieve the best outcome across a certain policy class. Yet these methods are rarely interpretable. However, interpretability is often a prerequisite for policy learning in clinical practice. In this paper, we propose an algorithm for interpretable off-policy learning via hyperbox search. In particular, our policies can be represented in disjunctive normal form (i.e., OR-of-ANDs) and are thus intelligible. We prove a universal approximation theorem that shows that our policy class is flexible enough to approximate any measurable function arbitrarily well. For optimization, we develop a tailored column generation procedure within a branch-and-bound framework. Using a simulation study, we demonstrate that our algorithm outperforms state-of-the-art methods from interpretable off-policy learning in terms of regret. Using real-word clinical data, we perform a user study with actual clinical experts, who rate our policies as highly interpretable.

stat.ML↗

Normalizing Flows for Interventional Density Estimation

Existing machine learning methods for causal inference usually estimate quantities expressed via the mean of potential outcomes (e.g., average treatment effect). However, such quantities do not capture the full information about the distribution of potential outcomes. In this work, we estimate the density of potential outcomes after interventions from observational data. For this, we propose a novel, fully-parametric deep learning method called Interventional Normalizing Flows. Specifically, we combine two normalizing flows, namely (i) a nuisance flow for estimating nuisance parameters and (ii) a target flow for parametric estimation of the density of potential outcomes. We further develop a tractable optimization objective based on a one-step bias correction for efficient and doubly robust estimation of the target flow parameters. As a result, our Interventional Normalizing Flows offer a properly normalized density estimator. Across various experiments, we demonstrate that our Interventional Normalizing Flows are expressive and highly effective, and scale well with both sample size and high-dimensional confounding. To the best of our knowledge, our Interventional Normalizing Flows are the first proper fully-parametric, deep learning method for density estimation of potential outcomes.

cs.LG↗

Learning Optimal Dynamic Treatment Regimes Using Causal Tree Methods in Medicine

Dynamic treatment regimes (DTRs) are used in medicine to tailor sequential treatment decisions to patients by considering patient heterogeneity. Common methods for learning optimal DTRs, however, have shortcomings: they are typically based on outcome prediction and not treatment effect estimation, or they use linear models that are restrictive for patient data from modern electronic health records. To address these shortcomings, we develop two novel methods for learning optimal DTRs that effectively handle complex patient data. We call our methods DTR-CT and DTR-CF. Our methods are based on a data-driven estimation of heterogeneous treatment effects using causal tree methods, specifically causal trees and causal forests, that learn non-linear relationships, control for time-varying confounding, are doubly robust, and explainable. To the best of our knowledge, our paper is the first that adapts causal tree methods for learning optimal DTRs. We evaluate our proposed methods using synthetic data and then apply them to real-world data from intensive care units. Our methods outperform state-of-the-art baselines in terms of cumulative regret and percentage of optimal decisions by a considerable margin. Our work improves treatment recommendations from electronic health record and is thus of direct relevance for personalized medicine.

stat.ML↗

A comparison of short-term probabilistic forecasts for the incidence of COVID-19 using mechanistic and statistical time series models

Short-term forecasts of infectious disease spread are a critical component in risk evaluation and public health decision making. While different models for short-term forecasting have been developed, open questions about their relative performance remain. Here, we compare short-term probabilistic forecasts of popular mechanistic models based on the renewal equation with forecasts of statistical time series models. Our empirical comparison is based on data of the daily incidence of COVID-19 across six large US states over the first pandemic year. We find that, on average, probabilistic forecasts from statistical time series models are overall at least as accurate as forecasts from mechanistic models. Moreover, statistical time series models better capture volatility. Our findings suggest that domain knowledge, which is integrated into mechanistic models by making assumptions about disease dynamics, does not improve short-term forecasts of disease incidence. We note, however, that forecasting is often only one of many objectives and thus mechanistic models remain important, for example, to model the impact of vaccines or the emergence of new variants.

stat.AP↗

Finding Qs: Profiling QAnon Supporters on Parler

The social media platform "Parler" has emerged into a prominent fringe community where a significant part of the user base are self-reported supporters of QAnon, a far-right conspiracy theory alleging that a cabal of elites controls global politics. QAnon is considered to have had an influential role in the public discourse during the 2020 U.S. presidential election. However, little is known about QAnon supporters on Parler and what sets them aside from other users. Building up on social identity theory, we aim at profiling the characteristics of QAnon supporters on Parler. We analyze a large-scale dataset with more than 600,000 profiles of English-speaking users on Parler. Based on users' profiles, posts, and comments, we then extract a comprehensive set of user features, linguistic features, network features, and content features. This allows us to perform user profiling and understand to what extent these features discriminate between QAnon and non-QAnon supporters on Parler. Our analysis is three-fold: (1) We quantify the number of QAnon supporters on Parler, finding that 34,913 users (5.5% of all users) openly report to support the conspiracy. (2) We examine differences between QAnon vs. non-QAnon supporters. We find that QAnon supporters differ statistically significantly from non-QAnon supporters across multiple dimensions. For example, they have, on average, a larger number of followers, followees, and posts, and thus have a large impact on the Parler network. (3) We use machine learning to identify which user characteristics discriminate QAnon from non-QAnon supporters. We find that user features, linguistic features, network features, and content features, can - to a large extent - discriminate QAnon vs. non-QAnon supporters on Parler. In particular, we find that user features are highly discriminatory, followed by content features and linguistic features.

cs.SI↗

Addressing distributional shifts in operations management: The case of order fulfillment in customized production

To meet order fulfillment targets, manufacturers seek to optimize production schedules. Machine learning can support this objective by predicting throughput times on production lines given order specifications. However, this is challenging when manufacturers produce customized products because customization often leads to changes in the probability distribution of operational data -- so-called distributional shifts. Distributional shifts can harm the performance of predictive models when deployed to future customer orders with new specifications. The literature provides limited advice on how such distributional shifts can be addressed in operations management. Here, we propose a data-driven approach based on adversarial learning and job shop scheduling, which allows us to account for distributional shifts in manufacturing settings with high degrees of product customization. We empirically validate our proposed approach using real-world data from a job shop production that supplies large metal components to an oil platform construction yard. Across an extensive series of numerical experiments, we find that our adversarial learning approach outperforms common baselines. Overall, this paper shows how production managers can improve their decision-making under distributional shifts.

stat.AP↗

Estimating Conditional Average Treatment Effects with Missing Treatment Information

Estimating conditional average treatment effects (CATE) is challenging, especially when treatment information is missing. Although this is a widespread problem in practice, CATE estimation with missing treatments has received little attention. In this paper, we analyze CATE estimation in the setting with missing treatments where unique challenges arise in the form of covariate shifts. We identify two covariate shifts in our setting: (i) a covariate shift between the treated and control population; and (ii) a covariate shift between the observed and missing treatment population. We first theoretically show the effect of these covariate shifts by deriving a generalization bound for estimating CATE in our setting with missing treatments. Then, motivated by our bound, we develop the missing treatment representation network (MTRNet), a novel CATE estimation algorithm that learns a balanced representation of covariates using domain adaptation. By using balanced representations, MTRNet provides more reliable CATE estimates in the covariate domains where the data are not fully observed. In various experiments with semi-synthetic and real-world data, we show that our algorithm improves over the state-of-the-art by a substantial margin.

stat.ML↗

Leveraging driver vehicle and environment interaction: Machine learning using driver monitoring cameras to detect drunk driving

Excessive alcohol consumption causes disability and death. Digital interventions are promising means to promote behavioral change and thus prevent alcohol-related harm, especially in critical moments such as driving. This requires real-time information on a person's blood alcohol concentration (BAC). Here, we develop an in-vehicle machine learning system to predict critical BAC levels. Our system leverages driver monitoring cameras mandated in numerous countries worldwide. We evaluate our system with n=30 participants in an interventional simulator study. Our system reliably detects driving under any alcohol influence (area under the receiver operating characteristic curve [AUROC] 0.88) and driving above the WHO recommended limit of 0.05g/dL BAC (AUROC 0.79). Model inspection reveals reliance on pathophysiological effects associated with alcohol consumption. To our knowledge, we are the first to rigorously evaluate the use of driver monitoring cameras for detecting drunk driving. Our results highlight the potential of driver monitoring cameras and enable next-generation drunk driver interaction preventing alcohol-related harm.

cs.HC↗

Mechanisms of True and False Rumor Sharing in Social Media: Collective Intelligence or Herd Behavior?

Social media platforms disseminate extensive volumes of online content, including true and, in particular, false rumors. Previous literature has studied the diffusion of offline rumors, yet more research is needed to understand the diffusion of online rumors. In this paper, we examine the role of lifetime and crowd effects in social media sharing behavior for true vs. false rumors. Based on 126,301 Twitter cascades, we find that the sharing behavior is characterized by lifetime and crowd effects that explain differences in the spread of true as opposed to false rumors. All else equal, we find that a longer lifetime is associated with less sharing activities, yet the reduction in sharing is larger for false than for true rumors. Hence, lifetime is an important determinant explaining why false rumors die out. Furthermore, we find that the spread of false rumors is characterized by herding tendencies (rather than collective intelligence), whereby the spread of false rumors becomes proliferated at a larger retweet depth. These findings explain differences in the diffusion dynamics of true and false rumors and further offer practical implications for social media platforms.

cs.SI↗

Analyzing Social Media Activities at Bellingcat

Open-source journalism emerged as a new phenomenon in the media ecosystem, which uses crowdsourcing to fact-check and generate investigative reports for world events using open sources (e.g., social media). A particularly prominent example is Bellingcat. Bellingcat is known for its investigations on the illegal use of chemical weapons during the Syrian war, the Russian responsibility for downing flight MH17, the identification of the perpetrators in the attempted murder of Alexei Navalny, and war crimes in the Russo-Ukraine war. Crucial for this is social media in order to disseminate findings and crowdsource fact-checks. In this work, we characterize the social media activities at Bellingcat on Twitter. For this, we built a comprehensive dataset of all N=24,682 tweets posted by Bellingcat on Twitter since its inception in July 2014. Our analysis is three-fold: (1) We analyze how Bellingcat uses Twitter to disseminate information and collect information from its follower base. Here, we find a steady increase in both posts and replies over time, particularly during the Russo-Ukrainian war, which is in line with the growing importance of Bellingcat for the traditional media ecosystem. (2) We identify characteristics of posts that are successful in eliciting user engagement. User engagement is particularly large for posts embedding additional media items and with a more negative sentiment. (3) We examine how the follower base has responded to the Russian invasion of Ukraine. Here, we find that the sentiment has become more polarized and negative. We attribute this to a ~13-fold increase in bots interacting with the Bellingcat account. Overall, our findings provide recommendations for how open-source journalism such as Bellingcat can successfully operate on social media.

cs.SI↗

Contrastive Learning for Unsupervised Domain Adaptation of Time Series

Unsupervised domain adaptation (UDA) aims at learning a machine learning model using a labeled source domain that performs well on a similar yet different, unlabeled target domain. UDA is important in many applications such as medicine, where it is used to adapt risk scores across different patient cohorts. In this paper, we develop a novel framework for UDA of time series data, called CLUDA. Specifically, we propose a contrastive learning framework to learn contextual representations in multivariate time series, so that these preserve label information for the prediction task. In our framework, we further capture the variation in the contextual representations between source and target domain via a custom nearest-neighbor contrastive learning. To the best of our knowledge, ours is the first framework to learn domain-invariant, contextual representation for UDA of time series data. We evaluate our framework using a wide range of time series datasets to demonstrate its effectiveness and show that it achieves state-of-the-art performance for time series UDA.

cs.LG↗

New threats to society from free-speech social media platforms

In recent years, several free-speech social media platforms (so-called "alt-techs") have emerged, such as Parler, Gab, and Telegram. These platforms market themselves as alternatives to mainstream social media and proclaim "free-speech" due to the absence of content moderation, which has been attracting a large base of partisan users, extremists, and supporters of conspiracy theories. In this comment, we discuss some of the threats that emerge from such social media platforms and call for more policy efforts directed at understanding and countering the risks for society.

cs.SI↗

Estimating average causal effects from patient trajectories

In medical practice, treatments are selected based on the expected causal effects on patient outcomes. Here, the gold standard for estimating causal effects are randomized controlled trials; however, such trials are costly and sometimes even unethical. Instead, medical practice is increasingly interested in estimating causal effects among patient (sub)groups from electronic health records, that is, observational data. In this paper, we aim at estimating the average causal effect (ACE) from observational data (patient trajectories) that are collected over time. For this, we propose DeepACE: an end-to-end deep learning model. DeepACE leverages the iterative G-computation formula to adjust for the bias induced by time-varying confounders. Moreover, we develop a novel sequential targeting procedure which ensures that DeepACE has favorable theoretical properties, i.e., is doubly robust and asymptotically efficient. To the best of our knowledge, this is the first work that proposes an end-to-end deep learning model tailored for estimating time-varying ACEs. We compare DeepACE in an extensive number of experiments, confirming that it achieves state-of-the-art performance. We further provide a case study for patients suffering from low back pain to demonstrate that DeepACE generates important and meaningful findings for clinical practice. Our work enables practitioners to develop effective treatment recommendations based on population effects.

stat.ML↗

Estimating individual treatment effects under unobserved confounding using binary instruments

Estimating conditional average treatment effects (CATEs) from observational data is relevant in many fields such as personalized medicine. However, in practice, the treatment assignment is usually confounded by unobserved variables and thus introduces bias. A remedy to remove the bias is the use of instrumental variables (IVs). Such settings are widespread in medicine (e.g., trials where the treatment assignment is used as binary IV). In this paper, we propose a novel, multiply robust machine learning framework, called MRIV, for estimating CATEs using binary IVs and thus yield an unbiased CATE estimator. Different from previous work for binary IVs, our framework estimates the CATE directly via a pseudo outcome regression. (1)~We provide a theoretical analysis where we show that our framework yields multiple robust convergence rates: our CATE estimator achieves fast convergence even if several nuisance estimators converge slowly. (2)~We further show that our framework asymptotically outperforms state-of-the-art plug-in IV methods for CATE estimation, in the sense that it achieves a faster rate of convergence if the CATE is smoother than the individual outcome surfaces. (3)~We build upon our theoretical results and propose a tailored deep neural network architecture called MRIV-Net for CATE estimation using binary IVs. Across various computational experiments, we demonstrate empirically that our MRIV-Net achieves state-of-the-art performance. To the best of our knowledge, our MRIV is the first multiply robust machine learning framework tailored to estimating CATEs in the binary IV setting.

stat.ME↗

QA Domain Adaptation using Hidden Space Augmentation and Self-Supervised Contrastive Adaptation

Question answering (QA) has recently shown impressive results for answering questions from customized domains. Yet, a common challenge is to adapt QA models to an unseen target domain. In this paper, we propose a novel self-supervised framework called QADA for QA domain adaptation. QADA introduces a novel data augmentation pipeline used to augment training QA samples. Different from existing methods, we enrich the samples via hidden space augmentation. For questions, we introduce multi-hop synonyms and sample augmented token embeddings with Dirichlet distributions. For contexts, we develop an augmentation method which learns to drop context spans via a custom attentive sampling strategy. Additionally, contrastive learning is integrated in the proposed self-supervised adaptation framework QADA. Unlike existing approaches, we generate pseudo labels and propose to train the model via a novel attention-based contrastive adaptation method. The attention weights are used to build informative features for discrepancy estimation that helps the QA model separate answers and generalize across source and target domains. To the best of our knowledge, our work is the first to leverage hidden space augmentation and attention-based contrastive adaptation for self-supervised domain adaptation in QA. Our evaluation shows that QADA achieves considerable improvements on multiple target datasets over state-of-the-art baselines in QA domain adaptation.

cs.CL↗

"Is It My Turn?" Assessing Teamwork and Taskwork in Collaborative Immersive Analytics

Immersive analytics has the potential to promote collaboration in machine learning (ML). This is desired due to the specific characteristics of ML modeling in practice, namely the complexity of ML, the interdisciplinary approach in industry, and the need for ML interpretability. In this work, we introduce an augmented reality-based system for collaborative immersive analytics that is designed to support ML modeling in interdisciplinary teams. We conduct a user study to examine how collaboration unfolds when users with different professional backgrounds and levels of ML knowledge interact in solving different ML tasks. Specifically, we use the pair analytics methodology and performance assessments to assess collaboration and explore their interactions with each other and the system. Based on this, we provide qualitative and quantitative results on both teamwork and taskwork during collaboration. Our results show how our system elicits sustained collaboration as measured along six distinct dimensions. We finally make recommendations how immersive systems should be designed to elicit sustained collaboration in ML modeling.

cs.HC↗