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Stefan Hohenegger

Publications and source records attributed to Stefan Hohenegger.

At least 37 records · Page 2Linked to original sources

The Effective Theory of Quantum Black Holes

We explore the quantum nature of black holes by introducing an effective framework that takes into account deviations from the classical results. The approach is based on introducing quantum corrections to the classical Schwarzschild geometry in a way that is consistent with the physical scales of the black hole and its classical symmetries. This is achieved by organizing the quantum corrections in inverse powers of a physical distance. By solving the system in a self-consistent way we show that the derived physical quantities, such as event horizons, temperature and entropy can be expressed in a well defined expansion in the inverse powers of the black hole mass. The approach captures the general form of the quantum corrections to black hole physics without requiring to commit to a specific model of quantum gravity.

gr-qc↗

Variant-driven multi-wave pattern of COVID-19 via a Machine Learning analysis of spike protein mutations

Applying a ML approach to the temporal variability of the Spike protein sequence enables us to identify, classify and track emerging virus variants. Our analysis is unbiased, in the sense that it does not require any prior knowledge of the variant characteristics, and our results are validated by other informed methods that define variants based on the complete genome. Furthermore, correlating persistent variants of our approach to epidemiological data, we discover that each new wave of the COVID-19 pandemic is driven and dominated by a new emerging variant. Our results are therefore indispensable for further studies on the evolution of SARS-CoV-2 and the prediction of evolutionary patterns that determine current and future mutations of the Spike proteins, as well as their diversification and persistence during the viral spread. Moreover, our ML algorithm works as an efficient early warning system for the emergence of new persistent variants that may pose a threat of triggering a new wave of COVID-19. Capable of a timely identification of potential new epidemiological threats when the variant only represents 1% of the new sequences, our ML strategy is a crucial tool for decision makers to define short and long term strategies to curb future outbreaks. The same methodology can be applied to other viral diseases, influenza included, if sufficient sequencing data is available.

q-bio.GN↗

The field theoretical ABC of epidemic dynamics

Infectious diseases are a threat for human health with tremendous impact on our society at large. The recent COVID-19 pandemic, caused by the SARS-CoV-2, is the latest example of a highly infectious disease ravaging the world, since late 2019. It is therefore imperative to develop efficient mathematical models, able to substantially curb the damages of a pandemic by unveiling disease spreading dynamics and symmetries. This will help inform (non)-pharmaceutical prevention strategies. For the reasons above we wrote this report that goes at the heart of mathematical modelling of infectious disease diffusion by simultaneously investigating the underlying microscopic dynamics in terms of percolation models, effective description via compartmental models and the employment of temporal symmetries naturally encoded in the mathematical language of critical phenomena. Our report reviews these approaches and determines their common denominators, relevant for theoretical epidemiology and its link to important concepts in theoretical physics. We show that the different frameworks exhibit common features such as criticality and self-similarity under time rescaling. These features are naturally encoded within the unifying field theoretical approach. The latter leads to an efficient description of the time evolution of the disease via a framework in which (near) time-dilation invariance is explicitly realised. As important test of the relevance of symmetries we show how to mathematically account for observed phenomena such as multi-wave dynamics. The models presented here are of immediate relevance for different realms of scientific enquiry from medical applications to the understanding of human behaviour. Our review offers novel perspectives on how to model, capture, organise and understand epidemiological data and disease dynamics for modelling real-world phenomena.

q-bio.PE↗

Effective Mathematical Modelling of Health Passes during a Pandemic

We study the impact on the epidemiological dynamics of a class of restrictive measures that are aimed at reducing the number of contacts of individuals who have a higher risk of being infected with a transmittable disease. Such measures are currently either implemented or at least discussed in numerous countries worldwide to ward off a potential new wave of COVID-19 across Europe. They come in the form of Health Passes (HP), which grant full access to public life only to individuals with a certificate that proves that they have either been fully vaccinated, have recovered from a previous infection or have recently tested negative to SARS-Cov-19 . We develop both a compartmental model as well as an epidemic Renormalisation Group approach, which is capable of describing the dynamics over a longer period of time, notably an entire epidemiological wave. Introducing different versions of HPs in this model, we are capable of providing quantitative estimates on the effectiveness of the underlying measures as a function of the fraction of the population that is vaccinated and the vaccination rate. We apply our models to the latest COVID-19 wave in several European countries, notably Germany and Austria, which validate our theoretical findings.

q-bio.PE↗

Epidemiological theory of virus variants

We propose a physical theory underlying the temporal evolution of competing virus variants that relies on the existence of (quasi) fixed points capturing the large time scale invariance of the dynamics. To motivate our result we first modify the time-honoured compartmental models of the SIR type to account for the existence of competing variants and then show how their evolution can be naturally re-phrased in terms of flow equations ending at quasi fixed points. As the natural next step we employ (near) scale invariance to organise the time evolution of the competing variants within the effective description of the epidemic Renormalization Group framework. We test the resulting theory against the time evolution of COVID-19 virus variants that validate the theory empirically.

q-bio.PE↗

Diagrammatic Expansion of Non-Perturbative Little String Free Energies

In arXiv:1911.08172 we have studied the single-particle free energy of a class of Little String Theories of A-type, which are engineered by $N$ parallel M5-branes on a circle. To leading instanton order (from the perspective of the low energy $U(N)$ gauge theory) and partially also to higher order, a decomposition was observed, which resembles a Feynman diagrammatic expansion: external states are given by expansion coefficients of the $N=1$ BPS free energy and a quasi-Jacobi form that governs the BPS-counting of an M5-brane coupling to two M2-branes. The effective coupling functions were written as infinite series and similarities to modular graph functions were remarked. In the current work we continue and extend this study: Working with the full non-perturbative BPS free energy, we analyse in detail the cases $N=2,3$ and $4$. We argue that in these cases to leading instanton order all coupling functions can be written as a simple combination of two-point functions of a single free scalar field on the torus. We provide closed form expressions, which we conjecture to hold for generic $N$. To higher instanton order, we observe that a decomposition of the free energy in terms of higher point functions with the same external states is still possible but a priori not unique. We nevertheless provide evidence that tentative coupling functions are still combinations of scalar Greens functions, which are decorated with derivatives or multiplied with holomorphic Eisenstein series. We interpret these decorations as corrections of the leading order effective couplings and in particular link the latter to dihedral graph functions with bivalent vertices, which suggests an interpretation in terms of disconnected graphs.

hep-th↗

Symmetric Orbifold Theories from Little String Residues

We study a class of Little String Theories (LSTs) of A type, described by $N$ parallel M5-branes spread out on a circle and which in the low energy regime engineer supersymmetric gauge theories with $U(N)$ gauge group. The BPS states in this setting correspond to M2-branes stretched between the M5-branes. Generalising an observation made in arXiv:1706.04425, we provide evidence that the BPS counting functions of special subsectors of the latter exhibit a Hecke structure in the Nekrasov-Shatashvili (NS) limit, i.e. the different orders in an instanton expansion of the supersymmetric gauge theory are related through the action of Hecke operators. We extract $N$ distinct such reduced BPS counting functions from the full free energy of the LST with the help of contour integrals with respect to the gauge parameters of the $U(N)$ gauge group. Physically, the states captured by these functions correspond to configurations where the same number of M2-branes is stretched between some of these neighbouring M5-branes, while the remaining M5-branes are collapsed on top of each other and a particular singular contribution is extracted. The Hecke structures suggest that these BPS states form the spectra of symmetric orbifold CFTs. We furthermore show that to leading instanton order (in the NS-limit) the reduced BPS counting functions factorise into simpler building blocks. These building blocks are the expansion coefficients of the free energy for $N=1$ and the expansion of a particular function, which governs the counting of BPS states of a single M5-brane with single M2-branes ending on it on either side. To higher orders in the instanton expansion, we observe new elements appearing in this decomposition, whose coefficients are related through a holomorphic anomaly equation.

hep-th↗

Toward Exotic 6D Supergravities

We investigate exotic supergravity theories in 6D with maximal (4,0) and (3,1) supersymmetry, which were conjectured by C. Hull to exist and to describe strong coupling limits of ${\cal N}=8$ theories in 5D. These theories involve exotic gauge fields with non-standard Young tableaux representations, subject to (self-)duality constraints. We give novel actions in a 5+1 split of coordinates whose field equations reproduce those of the free bosonic (4,0) and (3,1) theory, respectively, including the (self-)duality relations. Evidence is presented for a master exceptional field theory formulation with an extended section constraint that, depending on the solution, produces the (4,0), (3,1) or the conventional (2,2) theory. We comment on the possible construction of a fully non-linear master exceptional field theory.

hep-th↗

From Little String Free Energies Towards Modular Graph Functions

We study the structure of the non-perturbative free energy of a one-parameter class of little string theories (LSTs) of A-type in the so-called unrefined limit. These theories are engineered by $N$ M5-branes probing a transverse flat space. By analysing a number of examples, we observe a pattern which suggests to write the free energy in a fashion that resembles a decomposition into higher-point functions which can be presented in a graphical way reminiscent of sums of (effective) Feynman diagrams: to leading order in the instanton parameter of the LST, the $N$ external states are given either by the fundamental building blocks of the theory with $N=1$, or the function that governs the counting of BPS states of a single M5-brane coupling to one M2-brane on either side. These states are connected via an effective coupling function which encodes the details of the gauge algebra of the LST and which in its simplest (non-trivial) form is captured by the scalar Greens function on the torus. More complicated incarnations of this function show certain similarities with so-called modular graph functions, which have appeared in the study of Feynman amplitudes in string- and field theory. Finally, similar structures continue to exist at higher instanton orders, which, however, also contain contributions that can be understood as the action of (Hecke) operators on the leading instanton result.

hep-th↗

Symmetries in A-Type Little String Theories, Part I

We analyse the symmetries of a class of A-type little string theories that are engineered by $N$ parallel M5-branes with M2-branes stretched between them. This paper deals with the so-called reduced free energy, which only receives contributions from the subset of the BPS states that carry the same charges under all the Cartan generators of the underlying gauge algebra. We argue (and check explicitly in a number of examples) that the former is invariant under the paramodular group $Σ_N\subset Sp(4,\mathbb{Q})$, which gets extended to a subgroup of $Sp(4,\mathbb{R})$ in the Nekrasov-Shatashvili-limit. This extension agrees with the observation made in arXiv:1706.04425 that these BPS states form a symmetric orbifold CFT. Furthermore, we argue that $Σ_N$ (along with other symmetries) places strong constraints on the BPS counting function that governs the intersection between the M5- and M2-branes.

hep-th↗

Symmetries in A-Type Little String Theories, Part II

We continue our study of symmetries of a class of little string theories of A-type, which are engineered by $N$ parallel M5-branes probing a flat transverse space. Extending the analysis of the companion paper, we discuss the part of the free energy that is sensitive to the details of the $\mathfrak{a}_{N-1}$ gauge structure, by computing explicit series expansions for the cases $N=2,3,4$. Based on these examples, we find a class of functions that we conjecture to resum whole sectors in the instanton expansion of the free energy and which combine in a natural manner its modular properties as well as the gauge symmetry. These functions have previously been introduced in the literature as the generating functions of multi-divisor sums and in the case $N=2$ can also be cast into the form of a generalised Eisenstein series. We use these resummed contributions to the free energy to perform a number of non-trivial consistency checks for our results.

hep-th↗

Dihedral Symmetries of Gauge Theories from Dual Calabi-Yau Threefolds

Recent studies (arXiv:1610.07916, arXiv:1711.07921, arXiv:1807.00186) of six-dimensional supersymmetric gauge theories that are engineered by a class of toric Calabi-Yau threefolds $X_{N,M}$, have uncovered a vast web of dualities. In this paper we analyse consequences of these dualities from the perspective of the partition functions $\mathcal{Z}_{N,M}$ (or the free energy $\mathcal{F}_{N,M}$) of these theories. Focusing on the case $M=1$, we find that the latter is invariant under the group $\mathbb{G}(N)\times S_N$: here $S_N$ corresponds to the Weyl group of the largest gauge group that can be engineered from $X_{N,1}$ and $\mathbb{G}(N)$ is a dihedral group, which acts in an intrinsically non-perturbative fashion and which is of infinite order for $N\geq 4$. We give an explicit representation of $\mathbb{G}(N)$ as a matrix group that is freely generated by two elements which act naturally on a specific basis of the Kähler moduli space of $X_{N,1}$. While we show the invariance of $\mathcal{Z}_{N,1}$ under $\mathbb{G}(N)\times S_N$ in full generality, we provide explicit checks by series expansions of $\mathcal{F}_{N,1}$ for a large number of examples. We also comment on the relation of $\mathbb{G}(N)$ to the modular group that arises due to the geometry of $X_{N,1}$ as a double elliptic fibration, as well as T-duality of Little String Theories that are constructed from $X_{N,1}$.

hep-th↗

Field Theory with Coordinate Dependent Noncommutativity

We discuss the formulation of classical field theoretical models on $n$-dimensional noncommutative space-time defined by a generic associative star product. A simple procedure for deriving conservation laws is presented and applied to field theories in noncommutative space-time to obtain local conservation laws (for the electric charge and for the energy-momentum tensor of free fields) and more generally an energy-momentum balance equation for interacting fields. For free field models an analogy with the damped harmonic oscillator in classical mechanics is pointed out, which allows us to get a physical understanding for the obtained conservation laws. To conclude, the formulation of field theories on curved noncommutative space is addressed.

hep-th↗

Five-Dimensional Gauge Theories from Shifted Web Diagrams

In previous works (arXiv:1610.07916, arXiv:1711.07921, arXiv:1807.00186) we studied a class of toric Calabi-Yau threefolds which engineer six-dimensional supersymmetric gauge theories with gauge group $U(N)$ and adjoint matter. The Kähler moduli space of these manifolds can be extended through flop transformations to include regions which are described by so-called shifted toric web diagrams. In this paper we analyse gauge theories that are engineered by these shifted toric web diagrams and argue that in specific limits, some of the them engineer five-dimensional quiver gauge theories with gauge group $G\subset U(N)$ and with fundamental and bi-fundamental matter. We discuss several examples in detail and describe how the matter sector is obtained from the six-dimensional parent theory.

hep-th↗

Beyond Triality: Dual Quiver Gauge Theories and Little String Theories

The web of dual gauge theories engineered from a class of toric Calabi-Yau threefolds is explored. In previous work, we have argued for a triality structure by compiling evidence for the fact that every such manifold $X_{N,M}$ (for given $(N,M)$) engineers three a priori different, weakly coupled quiver gauge theories in five dimensions. The strong coupling regime of the latter is in general described by Little String Theories. Furthermore, we also conjectured that the manifold $X_{N,M}$ is dual to $X_{N',M'}$ if $NM=N'M'$ and $\text{gcd}(N,M)=\text{gcd}(N',M')$. Combining this result with the triality structure, we currently argue for a large number of dual quiver gauge theories, whose instanton partition functions can be computed explicitly as specific expansions of the topological partition function $\mathcal{Z}_{N,M}$ of $X_{N,M}$. We illustrate this web of dual theories by studying explicit examples in detail. We also undertake first steps in further analysing the extended moduli space of $X_{N,M}$ with the goal of finding other dual gauge theories.

hep-th↗

Triality in Little String Theories

We study a class of eight-supercharge little string theories (LSTs) on the world-volume of $N$ M5-branes with transverse space $\mathbb{S}^{1}\times (\mathbb{C}^2/\mathbb{Z}_M)$. These M-brane configurations compactified on a circle are dual to $M$ D5-branes intersecting $N$ NS5-branes on $\mathbb{T}^2\times \mathbb{R}^{7,1}$ as well as to F-theory compactified on a toric Calabi-Yau threefold $X_{N,M}$. We argue that the Kähler cone of $X_{N,M}$ admits three regions associated with weakly coupled quiver gauge theories of gauge groups $[U(N)]^M, [U(M)]^N$ and $[U(\frac{NM}{k})]^k$ where $k=\mbox{gcd}(N,M)$. These provide low-energy descriptions of different LSTs. The duality between the first two gauge theories is well known and is a consequence of the S-duality between D5- and NS5-branes or the T-duality of the LSTs. The triality involving the third gauge theory is new and we demonstrate it using several examples. We also discuss implications of this triality for the W-algebras associated with the Alday-Gaiotto-Tachikawa dual theories.

hep-th↗

Dual Little Strings and their Partition Functions

We study the topological string partition function of a class of toric, double elliptically fibered Calabi-Yau threefolds $X_{N,M}$ at a generic point in the Kähler moduli space. These manifolds engineer little string theories in five dimensions or lower and are dual to stacks of M5-branes probing a transverse orbifold singularity. Using the refined topological vertex formalism, we explicitly calculate a generic building block which allows to compute the topological string partition function of $X_{N,M}$ as a series expansion in different Kähler parameters. Using this result we give further explicit proof for a duality found previously in the literature, which relates $X_{N,M}\sim X_{N',M'}$ for $NM=N'M'$ and $\text{gcd}(N,M)=\text{gcd}(N',M')$.

hep-th↗

Five-Brane Webs and Highest Weight Representations

We consider BPS-counting functions $\mathcal{Z}_{N,M}$ of $N$ parallel M5-branes probing a transverse $\mathbb{Z}_M$ orbifold geometry. These brane web configurations can be dualised into a class of toric non-compact Calabi-Yau threefolds which have the structure of an elliptic fibration over (affine) $A_{N-1}$. We make this symmetry of $\mathcal{Z}_{N,M}$ manifest in particular regions of the parameter space of the setup: we argue that for specific choices of the deformation parameters, the supercharges of the system acquire particular holonomy charges which lead to infinitely many cancellations among states contributing to the partition function. The resulting (simplified) $\mathcal{Z}_{N,M}$ can be written as a sum over weights forming a single irreducible representation of the Lie algebra $\mathfrak{a}_{N-1}$ (or its affine counterpart). We show this behaviour explicitly for an extensive list of examples for specific values of $(N,M)$ and generalise the arising pattern for generic configurations. Finally, for a particular compact M5-brane setup we use this form of the partition function to make the duality $N\leftrightarrow M$ manifest.

hep-th↗