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Stefan Huber

Publications and source records attributed to Stefan Huber.

At least 37 records · Page 2Linked to original sources

What are the limits to biomedical research acceleration through general-purpose AI?

Although general-purpose artificial intelligence (GPAI) is widely expected to accelerate scientific discovery, its practical limits in biomedicine remain unclear. We assess this potential by developing a framework of GPAI capabilities across the biomedical research lifecycle. Our scoping literature review indicates that current GPAI could deliver a speed increase of around 2x, whereas future GPAI could facilitate strong acceleration of up to 25x for physical tasks and 100x for cognitive tasks. However, achieving these gains may be severely limited by factors such as irreducible biological constraints, research infrastructure, data access, and the need for human oversight. Our expert elicitation with eight senior biomedical researchers revealed skepticism regarding the strong acceleration of tasks such as experiment design and execution. In contrast, strong acceleration of manuscript preparation, review and publication processes was deemed plausible. Notably, all experts identified the assimilation of new tools by the scientific community as a critical bottleneck. Realising the potential of GPAI will therefore require more than technological progress; it demands targeted investment in shared automation infrastructure and systemic reforms to research and publication practices.

cs.CY↗

Energy Optimized Piecewise Polynomial Approximation Utilizing Modern Machine Learning Optimizers

This work explores an extension of machine learning-optimized piecewise polynomial approximation by incorporating energy optimization as an additional objective. Traditional closed-form solutions enable continuity and approximation targets but lack flexibility in accommodating complex optimization goals. By leveraging modern gradient descent optimizers within TensorFlow, we introduce a framework that minimizes elastic strain energy in cam profiles, leading to smoother motion. Experimental results confirm the effectiveness of this approach, demonstrating its potential to Pareto-efficiently trade approximation quality against energy consumption.

cs.LG↗

Comparing performance of variational quantum algorithm simulations on HPC systems

Variational quantum algorithms are of special importance in the research on quantum computing applications because of their applicability to current Noisy Intermediate-Scale Quantum (NISQ) devices. The main building blocks of these algorithms (among them, the definition of the Hamiltonian and of the ansatz, the optimizer) define a relatively large parameter space, making the comparison of results and performance between different approaches and software simulators cumbersome and prone to errors. In this paper, we employ a generic description of the problem, in terms of both Hamiltonian and ansatz, to port a problem definition consistently among different simulators. Three use cases of relevance for current quantum hardware (ground state calculation for the Hydrogen molecule, MaxCut, Travelling Salesman Problem) have been run on a set of HPC systems and software simulators to study the dependence of performance on the runtime environment, the scalability of the simulation codes and the mutual agreement of the physical results, respectively. The results show that our toolchain can successfully translate a problem definition between different simulators. On the other hand, variational algorithms are limited in their scaling by the long runtimes with respect to their memory footprint, so they expose limited parallelism to computation. This shortcoming is partially mitigated by using techniques like job arrays. The potential of the parser tool for exploring HPC performance and comparisons of results of variational algorithm simulations is highlighted.

quant-ph↗

Persistence-based Hough Transform for Line Detection

The Hough transform is a popular and classical technique in computer vision for the detection of lines (or more general objects). It maps a pixel into a dual space -- the Hough space: each pixel is mapped to the set of lines through this pixel, which forms a curve in Hough space. The detection of lines then becomes a voting process to find those lines that received many votes by pixels. However, this voting is done by thresholding, which is susceptible to noise and other artifacts. In this work, we present an alternative voting technique to detect peaks in the Hough space based on persistent homology, which very naturally addresses limitations of simple thresholding. Experiments on synthetic data show that our method significantly outperforms the original method, while also demonstrating enhanced robustness. This work seeks to inspire future research in two key directions. First, we highlight the untapped potential of Topological Data Analysis techniques and advocate for their broader integration into existing methods, including well-established ones. Secondly, we initiate a discussion on the mathematical stability of the Hough transform, encouraging exploration of mathematically grounded improvements to enhance its robustness.

cs.CV↗

Topology-driven identification of repetitions in multi-variate time series

Many multi-variate time series obtained in the natural sciences and engineering possess a repetitive behavior, as for instance state-space trajectories of industrial machines in discrete automation. Recovering the times of recurrence from such a multi-variate time series is of a fundamental importance for many monitoring and control tasks. For a periodic time series this is equivalent to determining its period length. In this work we present a persistent homology framework to estimate recurrence times in multi-variate time series with different generalizations of cyclic behavior (periodic, repetitive, and recurring). To this end, we provide three specialized methods within our framework that are provably stable and validate them using real-world data, including a new benchmark dataset from an injection molding machine.

cs.CG↗

Multi-Objective Reinforcement Learning for Energy-Efficient Industrial Control

Industrial automation increasingly demands energy-efficient control strategies to balance performance with environmental and cost constraints. In this work, we present a multi-objective reinforcement learning (MORL) framework for energy-efficient control of the Quanser Aero 2 testbed in its one-degree-of-freedom configuration. We design a composite reward function that simultaneously penalizes tracking error and electrical power consumption. Preliminary experiments explore the influence of varying the Energy penalty weight, alpha, on the trade-off between pitch tracking and energy savings. Our results reveal a marked performance shift for alpha values between 0.0 and 0.25, with non-Pareto optimal solutions emerging at lower alpha values, on both the simulation and the real system. We hypothesize that these effects may be attributed to artifacts introduced by the adaptive behavior of the Adam optimizer, which could bias the learning process and favor bang-bang control strategies. Future work will focus on automating alpha selection through Gaussian Process-based Pareto front modeling and transitioning the approach from simulation to real-world deployment.

eess.SY↗

The Crucial Role of Problem Formulation in Real-World Reinforcement Learning

Reinforcement Learning (RL) offers promising solutions for control tasks in industrial cyber-physical systems (ICPSs), yet its real-world adoption remains limited. This paper demonstrates how seemingly small but well-designed modifications to the RL problem formulation can substantially improve performance, stability, and sample efficiency. We identify and investigate key elements of RL problem formulation and show that these enhance both learning speed and final policy quality. Our experiments use a one-degree-of-freedom (1-DoF) helicopter testbed, the Quanser Aero~2, which features non-linear dynamics representative of many industrial settings. In simulation, the proposed problem design principles yield more reliable and efficient training, and we further validate these results by training the agent directly on physical hardware. The encouraging real-world outcomes highlight the potential of RL for ICPS, especially when careful attention is paid to the design principles of problem formulation. Overall, our study underscores the crucial role of thoughtful problem formulation in bridging the gap between RL research and the demands of real-world industrial systems.

eess.SY↗

Neural Persistence Dynamics

We consider the problem of learning the dynamics in the topology of time-evolving point clouds, the prevalent spatiotemporal model for systems exhibiting collective behavior, such as swarms of insects and birds or particles in physics. In such systems, patterns emerge from (local) interactions among self-propelled entities. While several well-understood governing equations for motion and interaction exist, they are notoriously difficult to fit to data, as most prior work requires knowledge about individual motion trajectories, i.e., a requirement that is challenging to satisfy with an increasing number of entities. To evade such confounding factors, we investigate collective behavior from a $\textit{topological perspective}$, but instead of summarizing entire observation sequences (as done previously), we propose learning a latent dynamical model from topological features $\textit{per time point}$. The latter is then used to formulate a downstream regression task to predict the parametrization of some a priori specified governing equation. We implement this idea based on a latent ODE learned from vectorized (static) persistence diagrams and show that a combination of recent stability results for persistent homology justifies this modeling choice. Various (ablation) experiments not only demonstrate the relevance of each model component but provide compelling empirical evidence that our proposed model - $\textit{Neural Persistence Dynamics}$ - substantially outperforms the state-of-the-art across a diverse set of parameter regression tasks.

cs.LG↗

A Generative Model Based Honeypot for Industrial OPC UA Communication

Industrial Operational Technology (OT) systems are increasingly targeted by cyber-attacks due to their integration with Information Technology (IT) systems in the Industry 4.0 era. Besides intrusion detection systems, honeypots can effectively detect these attacks. However, creating realistic honeypots for brownfield systems is particularly challenging. This paper introduces a generative model-based honeypot designed to mimic industrial OPC UA communication. Utilizing a Long ShortTerm Memory (LSTM) network, the honeypot learns the characteristics of a highly dynamic mechatronic system from recorded state space trajectories. Our contributions are twofold: first, we present a proof-of concept for a honeypot based on generative machine-learning models, and second, we publish a dataset for a cyclic industrial process. The results demonstrate that a generative model-based honeypot can feasibly replicate a cyclic industrial process via OPC UA communication. In the short-term, the generative model indicates a stable and plausible trajectory generation, while deviations occur over extended periods. The proposed honeypot implementation operates efficiently on constrained hardware, requiring low computational resources. Future work will focus on improving model accuracy, interaction capabilities, and extending the dataset for broader applications.

cs.NI↗

AsIf: Asset Interface Analysis of Industrial Automation Devices

As Industry 4.0 and the Industrial Internet of Things continue to advance, industrial control systems are increasingly adopting IT solutions, including communication standards and protocols. As these systems become more decentralized and interconnected, a critical need for enhanced security measures arises. Threat modeling is traditionally performed in structured brainstorming sessions involving domain and security experts. Such sessions, however, often fail to provide an exhaustive identification of assets and interfaces due to the lack of a systematic approach. This is a major issue, as it leads to poor threat modeling, resulting in insufficient mitigation strategies and, lastly, a flawed security architecture. We propose a method for the analysis of assets in industrial systems, with special focus on physical threats. Inspired by the ISO/OSI reference model, a systematic approach is introduced to help identify and classify asset interfaces. This results in an enriched system model of the asset, offering a comprehensive overview visually represented as an interface tree, thereby laying the foundation for subsequent threat modeling steps. To demonstrate the proposed method, the results of its application to a programmable logic controller (PLC) are presented. In support of this, a study involving a group of 12 security experts was conducted. Additionally, the study offers valuable insights into the experts' general perspectives and workflows on threat modeling.

cs.CR↗

Comparison of Model Predictive Control and Proximal Policy Optimization for a 1-DOF Helicopter System

This study conducts a comparative analysis of Model Predictive Control (MPC) and Proximal Policy Optimization (PPO), a Deep Reinforcement Learning (DRL) algorithm, applied to a 1-Degree of Freedom (DOF) Quanser Aero 2 system. Classical control techniques such as MPC and Linear Quadratic Regulator (LQR) are widely used due to their theoretical foundation and practical effectiveness. However, with advancements in computational techniques and machine learning, DRL approaches like PPO have gained traction in solving optimal control problems through environment interaction. This paper systematically evaluates the dynamic response characteristics of PPO and MPC, comparing their performance, computational resource consumption, and implementation complexity. Experimental results show that while LQR achieves the best steady-state accuracy, PPO excels in rise-time and adaptability, making it a promising approach for applications requiring rapid response and adaptability. Additionally, we have established a baseline for future RL-related research on this specific testbed. We also discuss the strengths and limitations of each control strategy, providing recommendations for selecting appropriate controllers for real-world scenarios.

eess.SY↗

Topological Data Analysis in smart manufacturing: State of the art and futuredirections

Topological Data Analysis (TDA) is a discipline that applies algebraic topology techniques to analyze complex, multi-dimensional data. Although it is a relatively new field, TDA has been widely and successfully applied across various domains, such as medicine, materials science, and biology. This survey provides an overview of the state of the art of TDA within a dynamic and promising application area: industrial manufacturing and production, particularly within the Industry 4.0 context. We have conducted a rigorous and reproducible literature search focusing on TDA applications in industrial production and manufacturing settings. The identified works are categorized based on their application areas within the manufacturing process and the types of input data. We highlight the principal advantages of TDA tools in this context, address the challenges encountered and the future potential of the field. Furthermore, we identify TDA methods that are currently underexploited in specific industrial areas and discuss how their application could be beneficial, with the aim of stimulating further research in this field. This work seeks to bridge the theoretical advancements in TDA with the practical needs of industrial production. Our goal is to serve as a guide for practitioners and researchers applying TDA in industrial production and manufacturing systems. We advocate for the untapped potential of TDA in this domain and encourage continued exploration and research.

cs.LG↗

Python-Based Reinforcement Learning on Simulink Models

This paper proposes a framework for training Reinforcement Learning agents using Python in conjunction with Simulink models. Leveraging Python's superior customization options and popular libraries like Stable Baselines3, we aim to bridge the gap between the established Simulink environment and the flexibility of Python for training bleeding edge agents. Our approach is demonstrated on the Quanser Aero 2, a versatile dual-rotor helicopter. We show that policies trained on Simulink models can be seamlessly transferred to the real system, enabling efficient development and deployment of Reinforcement Learning agents for control tasks. Through systematic integration steps, including C-code generation from Simulink, DLL compilation, and Python interface development, we establish a robust framework for training agents on Simulink models. Experimental results demonstrate the effectiveness of our approach, surpassing previous efforts and highlighting the potential of combining Simulink with Python for Reinforcement Learning research and applications.

cs.LG↗

Machine Learning Optimized Orthogonal Basis Piecewise Polynomial Approximation

Piecewise Polynomials (PPs) are utilized in several engineering disciplines, like trajectory planning, to approximate position profiles given in the form of a set of points. While the approximation target along with domain-specific requirements, like Ck -continuity, can be formulated as a system of equations and a result can be computed directly, such closed-form solutions posses limited flexibility with respect to polynomial degrees, polynomial bases or adding further domain-specific requirements. Sufficiently complex optimization goals soon call for the use of numerical methods, like gradient descent. Since gradient descent lies at the heart of training Artificial Neural Networks (ANNs), modern Machine Learning (ML) frameworks like TensorFlow come with a set of gradient-based optimizers potentially suitable for a wide range of optimization problems beyond the training task for ANNs. Our approach is to utilize the versatility of PP models and combine it with the potential of modern ML optimizers for the use in function approximation in 1D trajectory planning in the context of electronic cam design. We utilize available optimizers of the ML framework TensorFlow directly, outside of the scope of ANNs, to optimize model parameters of our PP model. In this paper, we show how an orthogonal polynomial basis contributes to improving approximation and continuity optimization performance. Utilizing Chebyshev polynomials of the first kind, we develop a novel regularization approach enabling clearly improved convergence behavior. We show that, using this regularization approach, Chebyshev basis performs better than power basis for all relevant optimizers in the combined approximation and continuity optimization setting and demonstrate usability of the presented approach within the electronic cam domain.

cs.LG↗

IT/OT Integration by Design

The four Industry 4.0 design principles information transparency, technical assistance, interconnection, and decentralized decisions pose challenges in integrating information technology (IT) and operational technology (OT) solutions in industrial systems. These different solutions have conflicting requirements, making interfaces between them problematic for both systems and organizations. An Industrial Business Process Twin (IBPT) entity, acting as an intermediary between the realms of IT and OT, has been proposed in a previous work, to effectively reduce the amount of required IT/OT interfaces in an attempt of overcoming this situation. In this work, we investigate the effects of this approach during the design phase. We argue that, by eliminating potentially conflicting direct interfaces between IT and OT stakeholders within the organizational structure, this approach effectively eliminates conflicting communication channels within the system design. In order to verify our argument, we develop a model of our IBPT concept according to the Reference Architecture Model Industrie 4.0 (RAMI4.0) using an Industry 4.0 scenario addressing the four essential Industry 4.0 design principles. Results show that the IBPT approach indeed eliminates potentially conflicting IT/OT interfaces during the system design phase.

cs.SE↗

Improvements for mlrose applied to the Traveling Salesperson Problem

In this paper we discuss the application of Artificial Intelligence (AI) to the exemplary industrial use case of the two-dimensional commissioning problem in a high-bay storage, which essentially can be phrased as an instance of Traveling Salesperson Problem (TSP). We investigate the mlrose library that provides an TSP optimizer based on various heuristic optimization techniques. Our focus is on two methods, namely Genetic Algorithm (GA) and Hill Climbing (HC), which are provided by mlrose. We present improvements for both methods that yield shorter tour lengths, by moderately exploiting the problem structure of TSP. That is, the proposed improvements have a generic character and are not limited to TSP only.

cs.NE↗

CSRX: A novel Crossover Operator for a Genetic Algorithm applied to the Traveling Salesperson Problem

In this paper, we revisit the application of Genetic Algorithm (GA) to the Traveling Salesperson Problem (TSP) and introduce a family of novel crossover operators that outperform the previous state of the art. The novel crossover operators aim to exploit symmetries in the solution space, which allows us to more effectively preserve well-performing individuals, namely the fitness invariance to circular shifts and reversals of solutions. These symmetries are general and not limited to or tailored to TSP specifically.

cs.NE↗

A Mini Review on the utilization of Reinforcement Learning with OPC UA

Reinforcement Learning (RL) is a powerful machine learning paradigm that has been applied in various fields such as robotics, natural language processing and game playing achieving state-of-the-art results. Targeted to solve sequential decision making problems, it is by design able to learn from experience and therefore adapt to changing dynamic environments. These capabilities make it a prime candidate for controlling and optimizing complex processes in industry. The key to fully exploiting this potential is the seamless integration of RL into existing industrial systems. The industrial communication standard Open Platform Communications UnifiedArchitecture (OPC UA) could bridge this gap. However, since RL and OPC UA are from different fields,there is a need for researchers to bridge the gap between the two technologies. This work serves to bridge this gap by providing a brief technical overview of both technologies and carrying out a semi-exhaustive literature review to gain insights on how RL and OPC UA are applied in combination. With this survey, three main research topics have been identified, following the intersection of RL with OPC UA. The results of the literature review show that RL is a promising technology for the control and optimization of industrial processes, but does not yet have the necessary standardized interfaces to be deployed in real-world scenarios with reasonably low effort.

cs.AI↗