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Stefan Wager

Publications and source records attributed to Stefan Wager.

At least 73 records · Page 4Linked to original sources

Covariate-Powered Empirical Bayes Estimation

We study methods for simultaneous analysis of many noisy experiments in the presence of rich covariate information. The goal of the analyst is to optimally estimate the true effect underlying each experiment. Both the noisy experimental results and the auxiliary covariates are useful for this purpose, but neither data source on its own captures all the information available to the analyst. In this paper, we propose a flexible plug-in empirical Bayes estimator that synthesizes both sources of information and may leverage any black-box predictive model. We show that our approach is within a constant factor of minimax for a simple data-generating model. Furthermore, we establish robust convergence guarantees for our method that hold under considerable generality, and exhibit promising empirical performance on both real and simulated data.

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Cross-Validation, Risk Estimation, and Model Selection

Cross-validation is a popular non-parametric method for evaluating the accuracy of a predictive rule. The usefulness of cross-validation depends on the task we want to employ it for. In this note, I discuss a simple non-parametric setting, and find that cross-validation is asymptotically uninformative about the expected test error of any given predictive rule, but allows for asymptotically consistent model selection. The reason for this phenomenon is that the leading-order error term of cross-validation doesn't depend on the model being evaluated, and so cancels out when we compare two models.

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Sparsity Double Robust Inference of Average Treatment Effects

Many popular methods for building confidence intervals on causal effects under high-dimensional confounding require strong "ultra-sparsity" assumptions that may be difficult to validate in practice. To alleviate this difficulty, we here study a new method for average treatment effect estimation that yields asymptotically exact confidence intervals assuming that either the conditional response surface or the conditional probability of treatment allows for an ultra-sparse representation (but not necessarily both). This guarantee allows us to provide valid inference for average treatment effect in high dimensions under considerably more generality than available baselines. In addition, we showcase that our results are semi-parametrically efficient.

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Estimating Treatment Effects with Causal Forests: An Application

We apply causal forests to a dataset derived from the National Study of Learning Mindsets, and consider resulting practical and conceptual challenges. In particular, we discuss how causal forests use estimated propensity scores to be more robust to confounding, and how they handle data with clustered errors.

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Offline Multi-Action Policy Learning: Generalization and Optimization

In many settings, a decision-maker wishes to learn a rule, or policy, that maps from observable characteristics of an individual to an action. Examples include selecting offers, prices, advertisements, or emails to send to consumers, as well as the problem of determining which medication to prescribe to a patient. While there is a growing body of literature devoted to this problem, most existing results are focused on the case where data comes from a randomized experiment, and further, there are only two possible actions, such as giving a drug to a patient or not. In this paper, we study the offline multi-action policy learning problem with observational data and where the policy may need to respect budget constraints or belong to a restricted policy class such as decision trees. We build on the theory of efficient semi-parametric inference in order to propose and implement a policy learning algorithm that achieves asymptotically minimax-optimal regret. To the best of our knowledge, this is the first result of this type in the multi-action setup, and it provides a substantial performance improvement over the existing learning algorithms. We then consider additional computational challenges that arise in implementing our method for the case where the policy is restricted to take the form of a decision tree. We propose two different approaches, one using a mixed integer program formulation and the other using a tree-search based algorithm.

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Debiased Inference of Average Partial Effects in Single-Index Models

We propose a method for average partial effect estimation in high-dimensional single-index models that is root-n-consistent and asymptotically unbiased given sparsity assumptions on the underlying regression model. This note was prepared as a comment on Wooldridge and Zhu [2018], forthcoming in the Journal of Business and Economic Statistics.

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denoiseR: A Package for Low Rank Matrix Estimation

We introduce denoiseR, an R package that provides a unified implementation of several state-of-the-art proposals for regularized low rank matrix estimation, along with automatic selection of the regularization parameters. We also extend these methods to allow for missing values. The regularization schemes discussed in this paper are built around singular-value shrinkage and bootstrap-based stability arguments. We illustrate how to use out package by applying it to several real and simulated datasets, and highlight strengths and weaknesses of the different implemented methods.

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Optimized Regression Discontinuity Designs

The increasing popularity of regression discontinuity methods for causal inference in observational studies has led to a proliferation of different estimating strategies, most of which involve first fitting non-parametric regression models on both sides of a treatment assignment boundary and then reporting plug-in estimates for the effect of interest. In applications, however, it is often difficult to tune the non-parametric regressions in a way that is well calibrated for the specific target of inference; for example, the model with the best global in-sample fit may provide poor estimates of the discontinuity parameter. In this paper, we propose an alternative method for estimation and statistical inference in regression discontinuity designs that uses numerical convex optimization to directly obtain the finite-sample-minimax linear estimator for the regression discontinuity parameter, subject to bounds on the second derivative of the conditional response function. Given a bound on the second derivative, our proposed method is fully data-driven, and provides uniform confidence intervals for the regression discontinuity parameter with both discrete and continuous running variables. The method also naturally extends to the case of multiple running variables.

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Generalized Random Forests

We propose generalized random forests, a method for non-parametric statistical estimation based on random forests (Breiman, 2001) that can be used to fit any quantity of interest identified as the solution to a set of local moment equations. Following the literature on local maximum likelihood estimation, our method considers a weighted set of nearby training examples; however, instead of using classical kernel weighting functions that are prone to a strong curse of dimensionality, we use an adaptive weighting function derived from a forest designed to express heterogeneity in the specified quantity of interest. We propose a flexible, computationally efficient algorithm for growing generalized random forests, develop a large sample theory for our method showing that our estimates are consistent and asymptotically Gaussian, and provide an estimator for their asymptotic variance that enables valid confidence intervals. We use our approach to develop new methods for three statistical tasks: non-parametric quantile regression, conditional average partial effect estimation, and heterogeneous treatment effect estimation via instrumental variables. A software implementation, grf for R and C++, is available from CRAN.

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Approximate Residual Balancing: De-Biased Inference of Average Treatment Effects in High Dimensions

There are many settings where researchers are interested in estimating average treatment effects and are willing to rely on the unconfoundedness assumption, which requires that the treatment assignment be as good as random conditional on pre-treatment variables. The unconfoundedness assumption is often more plausible if a large number of pre-treatment variables are included in the analysis, but this can worsen the performance of standard approaches to treatment effect estimation. In this paper, we develop a method for de-biasing penalized regression adjustments to allow sparse regression methods like the lasso to be used for sqrt{n}-consistent inference of average treatment effects in high-dimensional linear models. Given linearity, we do not need to assume that the treatment propensities are estimable, or that the average treatment effect is a sparse contrast of the outcome model parameters. Rather, in addition standard assumptions used to make lasso regression on the outcome model consistent under 1-norm error, we only require overlap, i.e., that the propensity score be uniformly bounded away from 0 and 1. Procedurally, our method combines balancing weights with a regularized regression adjustment.

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Estimation and Inference of Heterogeneous Treatment Effects using Random Forests

Many scientific and engineering challenges -- ranging from personalized medicine to customized marketing recommendations -- require an understanding of treatment effect heterogeneity. In this paper, we develop a non-parametric causal forest for estimating heterogeneous treatment effects that extends Breiman's widely used random forest algorithm. In the potential outcomes framework with unconfoundedness, we show that causal forests are pointwise consistent for the true treatment effect, and have an asymptotically Gaussian and centered sampling distribution. We also discuss a practical method for constructing asymptotic confidence intervals for the true treatment effect that are centered at the causal forest estimates. Our theoretical results rely on a generic Gaussian theory for a large family of random forest algorithms. To our knowledge, this is the first set of results that allows any type of random forest, including classification and regression forests, to be used for provably valid statistical inference. In experiments, we find causal forests to be substantially more powerful than classical methods based on nearest-neighbor matching, especially in the presence of irrelevant covariates.

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Shape-constrained partial identification of a population mean under unknown probabilities of sample selection

A prevailing challenge in the biomedical and social sciences is to estimate a population mean from a sample obtained with unknown selection probabilities. Using a well-known ratio estimator, Aronow and Lee (2013) proposed a method for partial identification of the mean by allowing the unknown selection probabilities to vary arbitrarily between two fixed extreme values. In this paper, we show how to leverage auxiliary shape constraints on the population outcome distribution, such as symmetry or log-concavity, to obtain tighter bounds on the population mean. We use this method to estimate the performance of Aymara students---an ethnic minority in the north of Chile---in a national educational standardized test. We implement this method in the new statistical software package scbounds for R.

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Estimating Average Treatment Effects: Supplementary Analyses and Remaining Challenges

There is a large literature on semiparametric estimation of average treatment effects under unconfounded treatment assignment in settings with a fixed number of covariates. More recently attention has focused on settings with a large number of covariates. In this paper we extend lessons from the earlier literature to this new setting. We propose that in addition to reporting point estimates and standard errors, researchers report results from a number of supplementary analyses to assist in assessing the credibility of their estimates.

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High-dimensional regression adjustments in randomized experiments

We study the problem of treatment effect estimation in randomized experiments with high-dimensional covariate information, and show that essentially any risk-consistent regression adjustment can be used to obtain efficient estimates of the average treatment effect. Our results considerably extend the range of settings where high-dimensional regression adjustments are guaranteed to provide valid inference about the population average treatment effect. We then propose cross-estimation, a simple method for obtaining finite-sample-unbiased treatment effect estimates that leverages high-dimensional regression adjustments. Our method can be used when the regression model is estimated using the lasso, the elastic net, subset selection, etc. Finally, we extend our analysis to allow for adaptive specification search via cross-validation, and flexible non-parametric regression adjustments with machine learning methods such as random forests or neural networks.

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Bootstrap-Based Regularization for Low-Rank Matrix Estimation

We develop a flexible framework for low-rank matrix estimation that allows us to transform noise models into regularization schemes via a simple bootstrap algorithm. Effectively, our procedure seeks an autoencoding basis for the observed matrix that is stable with respect to the specified noise model; we call the resulting procedure a stable autoencoder. In the simplest case, with an isotropic noise model, our method is equivalent to a classical singular value shrinkage estimator. For non-isotropic noise models, e.g., Poisson noise, the method does not reduce to singular value shrinkage, and instead yields new estimators that perform well in experiments. Moreover, by iterating our stable autoencoding scheme, we can automatically generate low-rank estimates without specifying the target rank as a tuning parameter.

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Asymptotic Theory for Random Forests

Random forests have proven to be reliable predictive algorithms in many application areas. Not much is known, however, about the statistical properties of random forests. Several authors have established conditions under which their predictions are consistent, but these results do not provide practical estimates of random forest errors. In this paper, we analyze a random forest model based on subsampling, and show that random forest predictions are asymptotically normal provided that the subsample size s scales as s(n)/n = o(log(n)^{-d}), where n is the number of training examples and d is the number of features. Moreover, we show that the asymptotic variance can consistently be estimated using an infinitesimal jackknife for bagged ensembles recently proposed by Efron (2014). In other words, our results let us both characterize and estimate the error-distribution of random forest predictions, thus taking a step towards making random forests tools for statistical inference instead of just black-box predictive algorithms.

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Adaptive Concentration of Regression Trees, with Application to Random Forests

We study the convergence of the predictive surface of regression trees and forests. To support our analysis we introduce a notion of adaptive concentration for regression trees. This approach breaks tree training into a model selection phase in which we pick the tree splits, followed by a model fitting phase where we find the best regression model consistent with these splits. We then show that the fitted regression tree concentrates around the optimal predictor with the same splits: as d and n get large, the discrepancy is with high probability bounded on the order of sqrt(log(d) log(n)/k) uniformly over the whole regression surface, where d is the dimension of the feature space, n is the number of training examples, and k is the minimum leaf size for each tree. We also provide rate-matching lower bounds for this adaptive concentration statement. From a practical perspective, our result enables us to prove consistency results for adaptively grown forests in high dimensions, and to carry out valid post-selection inference in the sense of Berk et al. [2013] for subgroups defined by tree leaves.

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Data Augmentation via Levy Processes

If a document is about travel, we may expect that short snippets of the document should also be about travel. We introduce a general framework for incorporating these types of invariances into a discriminative classifier. The framework imagines data as being drawn from a slice of a Levy process. If we slice the Levy process at an earlier point in time, we obtain additional pseudo-examples, which can be used to train the classifier. We show that this scheme has two desirable properties: it preserves the Bayes decision boundary, and it is equivalent to fitting a generative model in the limit where we rewind time back to 0. Our construction captures popular schemes such as Gaussian feature noising and dropout training, as well as admitting new generalizations.

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