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Steffen Lauritzen

Publications and source records attributed to Steffen Lauritzen.

22 records · Page 2Linked to original sources

Estimation of Parameters in DNA Mixture Analysis

In Cowell et al. (2007), a Bayesian network for analysis of mixed traces of DNA was presented using gamma distributions for modelling peak sizes in the electropherogram. It was demonstrated that the analysis was sensitive to the choice of a variance factor and hence this should be adapted to any new trace analysed. In the present paper we discuss how the variance parameter can be estimated by maximum likelihood to achieve this. The unknown proportions of DNA from each contributor can similarly be estimated by maximum likelihood jointly with the variance parameter. Furthermore we discuss how to incorporate prior knowledge about the parameters in a Bayesian analysis. The proposed estimation methods are illustrated through a few examples of applications for calculating evidential value in casework and for mixture deconvolution.

stat.ME↗

Proper local scoring rules

We investigate proper scoring rules for continuous distributions on the real line. It is known that the log score is the only such rule that depends on the quoted density only through its value at the outcome that materializes. Here we allow further dependence on a finite number $m$ of derivatives of the density at the outcome, and describe a large class of such $m$-local proper scoring rules: these exist for all even $m$ but no odd $m$. We further show that for $m\geq2$ all such $m$-local rules can be computed without knowledge of the normalizing constant of the distribution.

math.ST↗

Proper local scoring rules on discrete sample spaces

A scoring rule is a loss function measuring the quality of a quoted probability distribution $Q$ for a random variable $X$, in the light of the realized outcome $x$ of $X$; it is proper if the expected score, under any distribution $P$ for $X$, is minimized by quoting $Q=P$. Using the fact that any differentiable proper scoring rule on a finite sample space ${\mathcal{X}}$ is the gradient of a concave homogeneous function, we consider when such a rule can be local in the sense of depending only on the probabilities quoted for points in a nominated neighborhood of $x$. Under mild conditions, we characterize such a proper local scoring rule in terms of a collection of homogeneous functions on the cliques of an undirected graph on the space ${\mathcal{X}}$. A useful property of such rules is that the quoted distribution $Q$ need only be known up to a scale factor. Examples of the use of such scoring rules include Besag's pseudo-likelihood and Hyvärinen's method of ratio matching.

math.ST↗