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Stephan W. Anderson

Publications and source records attributed to Stephan W. Anderson.

12 recordsLinked to original sources

A Wireless Volumetric Metamaterial Resonator for Breast MRI

High-performance breast magnetic resonance imaging (MRI) remains limited by the availability, geometry, and cost of dedicated receive coils. In contrast, spine coils are widely installed in MR scanners globally but provide insufficient sensitivity for anterior breast tissue. Here, we report a wireless volumetric metamaterial resonator (VMR) that converts a standard built-in spine coil into a scalable breast MRI receiver platform without modifying the scanner hardware. The VMR consists of axially stacked coaxial resonant rings that support a co-rotating collective mode, producing a centrally concentrated RF magnetic field within the enclosed imaging volume. Leveraging distributed capacitance in the coaxial cable, gap-engineered geometric tuning, and PIN-diode-based self-detuning, the VMR enables size scalability, electric-field confinement, and transmit-receive compatibility, as validated through bench measurements and 3.0 T MRI experiments. Three VMR prototypes spanning small, medium, and large breast-equivalent volumes were designed and evaluated using electromagnetic simulations, bench measurements, and phantom MRI experiments. Compared with a commercial 16-channel breast coil, the VMR-augmented spine coil achieved more than 4-fold higher central SNR and reduced spatial non-uniformity from approximately 70% to 20% within the target imaging region. Under SENSE parallel imaging at acceleration factors of 2-4, the VMR-augmented spine coil maintained an average 4-fold higher central SNR than the commercial coil for three sizes. These results establish the VMR as a passive, scalable hardware strategy for improving breast MRI performance using existing clinical scanner infrastructure.

physics.med-ph

A Wireless Reconfigurable Metasurface for Enhanced Parallel Magnetic Resonance Imaging

Modern magnetic resonance imaging (MRI) relies on application-specific multi-channel receive coils to achieve high performance, but these coils are typically costly, rigid, and difficult to generalize across anatomies. Recent wireless, low-cost metamaterials offer improved signal-to-noise ratio (SNR) but remain anatomy-dependent, are prone to destructive inter-element interference, and lack demonstrated compatibility with parallel imaging. Herein, a wireless, reconfigurable coaxial loop metasurface (CLM) is introduced as a platform for localized SNR enhancement that can operate either as a standalone element or as an insertable add-on alongside existing clinical receive systems. Through its coaxial architecture and shared current pathways, the CLM establishes a collective in-phase resonant mode that enforces phase-coherent current distributions across all loops, resulting in consistently constructive interference. Benchmarking on a 3.0 T MR system using an 8-loop CLM shows SNR enhancements of up to 14.8-fold and 14.02-fold in the sagittal and axial planes, relative to the birdcage coil (BC). As an add-on to a clinical posterior receive array, it further demonstrates up to 2.9-fold SNR enhancement and compatibility with parallel imaging across ex vivo and in vivo settings. The proposed CLM paves the way toward a new class of reconfigurable and insertable MRI hardware for flexible and system-compatible signal enhancement.

physics.med-ph

Circularly polarized metamaterial cage for homogeneous signal-to-noise ratio enhancement in magnetic resonance imaging

The signal-to-noise ratio (SNR) in magnetic resonance imaging (MRI) governs the quality of signal detection and directly impacts the clarity and reliability of the acquired images. Recent advances in metamaterials have enabled lightweight solutions with selective magnetic responses, offering a route to locally boost SNR in targeted anatomical regions but often with compromised field homogeneity. Here, a wireless metamaterial cage constructed from coaxial cables is engineered for homogeneous SNR enhancement at 3.0 T. With its cylindrical geometry and electromagnetic architecture, the device supports circularly polarized resonance through engineered phase-shifted currents, enabling selective and omnidirectional interaction with the rotating B_1^- field to achieve uniform magnetic field distribution. Integrated with the body coil, the device yields a 32-fold SNR enhancement while maintaining comparable homogeneity to the body coil alone, exhibiting only 12.07% variation within the region of interest (ROI). Benchmarking against a state-of-the-art 16-channel extremity coil further shows that the metacage achieves at least 1.94-fold and 2.24-fold higher SNR in axial and coronal planes, respectively, and exhibits substantially lower SNR variation (12.07% compared to 54.83% for the extremity coil). The results establish the metacage as a compelling platform for next-generation wireless MRI technologies.

physics.med-ph

A robust near-field body area network based on coaxially-shielded textile metamaterial

A body area network (BAN) involving wearable sensors populated around the human body can continuously monitor physiological signals, finding applications in personal healthcare and athletic evaluation. Existing near-field communication (NFC)-enabled BAN solutions, while facilitating reliable and secure interconnection among battery-free sensors, face challenges such as limited spectral stability against external interference. Here we demonstrate a textile metamaterial featuring a coaxially-shielded internal structure designed to mitigate interference from extraneous loadings. The metamaterial can be patterned onto clothing to form a scalable, customizable network, enabling communication between NFC-enabled devices and developed battery-free textile NFC sensing nodes placed within the network. Proof of concept demonstration shows the metamaterial's robustness against mechanical deformation and exposure to lossy, conductive saline solutions, underscoring its potential applications in wet environments, particularly in athletic activities involving water or significant perspiration, offering insights for the future development of radio frequency components for a robust BAN at the system level.

physics.app-ph

Phased Gradient Ultra Open Metamaterials for Broadband Acoustic Silencing

Noise pollution is a persistent environmental concern with severe implications for human health and resources. Acoustic metamaterials offer the potential for ultrathin silencing devices; however, existing designs often lack practical openness and are thereby limited by their functional bandwidths. This paper introduces a novel approach utilizing a phase gradient ultra-open metamaterial (PGUOM) to address these challenges. The PGUOM, characterized by a phase gradient across three unit cells, efficiently transforms incident waves into spoof surface waves, effectively blocking sound while allowing for a high degree of ventilation. Our design provides adjustable openness, accommodates various boundary conditions, and ensures sustained broadband sound insulation. Theoretical, numerical, and experimental validations demonstrate the efficacy of our concept. This innovative approach represents a significant advancement in ventilated acoustic metamaterials, providing both ventilation and high-performance, broadband sound insulation simultaneously.

physics.app-ph

Wireless, Customizable Coaxially-shielded Coils for Magnetic Resonance Imaging

Anatomy-specific RF receive coil arrays routinely adopted in magnetic resonance imaging (MRI) for signal acquisition, are commonly burdened by their bulky, fixed, and rigid configurations, which may impose patient discomfort, bothersome positioning, and suboptimal sensitivity in certain situations. Herein, leveraging coaxial cables' inherent flexibility and electric field confining property, for the first time, we present wireless, ultra-lightweight, coaxially-shielded MRI coils achieving a signal-to-noise ratio (SNR) comparable to or surpassing that of commercially available cutting-edge receive coil arrays with the potential for improved patient comfort, ease of implementation, and significantly reduced costs. The proposed coils demonstrate versatility by functioning both independently in form-fitting configurations, closely adapting to relatively small anatomical sites, and collectively by inductively coupling together as metamaterials, allowing for extension of the field-of-view of their coverage to encompass larger anatomical regions without compromising coil sensitivity. The wireless, coaxially-shielded MRI coils reported herein pave the way toward next generation MRI coils.

physics.med-ph

Wearable Coaxially-shielded Metamaterial for Magnetic Resonance Imaging

Recent advancements in metamaterials have yielded the possibility of a wireless solution to improve signal-to-noise ratio (SNR) in magnetic resonance imaging (MRI). Unlike traditional closely packed local coil arrays with rigid designs and numerous components, these lightweight, cost-effective metamaterials eliminate the need for radio frequency (RF) cabling, baluns, adapters, and interfaces. However, their clinical adoption has been limited by their low sensitivity, bulky physical footprint, and limited, specific use cases. Herein, we introduce a wearable metamaterial developed using commercially available coaxial cable, designed for a 3.0 T MRI system. This metamaterial inherits the coaxially-shielded structure of its constituent coaxial cable, effectively containing the electric field within the cable, thereby mitigating the electric coupling to its loading while ensuring safer clinical adoption, lower signal loss, and resistance to frequency shifts. Weighing only 50g, the metamaterial maximizes its sensitivity by conforming to the anatomical region of interest. MRI images acquired using this metamaterial with various pulse sequences demonstrate an up to 2-fold SNR enhancement when compared to a state-of-the-art 16-channel knee coil. This work introduces a novel paradigm for constructing metamaterials in the MRI environment, paving the way for the development of next-generation wireless MRI technology.

physics.med-ph

Computational-design Enabled Wearable and Tunable Metamaterials via Freeform Auxetics for Magnetic Resonance Imaging

Metamaterials hold significant promise for enhancing the imaging capabilities of MRI machines as an additive technology, due to their unique ability to enhance local magnetic fields. However, despite their potential, the metamaterials reported in the context of MRI applications have often been impractical. This impracticality arises from their predominantly flat configurations and their susceptibility to shifts in resonance frequencies, preventing them from realizing their optimal performance. Here, we introduce a computational method for designing wearable and tunable metamaterials via freeform auxetics. The proposed computational-design tools yield an approach to solving the complex circle packing problems in an interactive and efficient manner, thus facilitating the development of deployable metamaterials configured in freeform shapes. With such tools, the developed metamaterials may readily conform to a patient's kneecap, ankle, head, or any part of the body in need of imaging, and while ensuring an optimal resonance frequency, thereby paving the way for the widespread adoption of metamaterials in clinical MRI applications.

physics.med-ph

Conformal Metamaterials with Active Tunability and Self-adaptivity for Magnetic Resonance Imaging

Ongoing effort has been devoted to applying metamaterials to boost the imaging performance of magnetic resonance imaging owing to their unique capacity for electromagnetic field confinement and enhancement. However, there are still major obstacles to widespread clinical adoption of conventional metamaterials due to several notable restrictions, namely: their typically bulky and rigid structures, deviations in their optimal resonance frequency, and their inevitable interference with the transmission RF field in MRI. Herein, we address these restrictions and report a conformal, smart metamaterial, which may not only be readily tuned to achieve the desired, precise frequency match with MRI by a controlling circuit, but is also capable of selectively amplifying the magnetic field during the RF reception phase by sensing the excitation signal strength passively, thereby remaining off during the RF transmission phase and thereby ensuring its optimal performance when applied to MRI as an additive technology. By addressing a host of current technological challenges, the metamaterial presented herein paves the way toward the wide-ranging utilization of metamaterials in clinical MRI, thereby translating this promising technology to the MRI bedside.

physics.med-ph

Attention Hybrid Variational Net for Accelerated MRI Reconstruction

The application of compressed sensing (CS)-enabled data reconstruction for accelerating magnetic resonance imaging (MRI) remains a challenging problem. This is due to the fact that the information lost in k-space from the acceleration mask makes it difficult to reconstruct an image similar to the quality of a fully sampled image. Multiple deep learning-based structures have been proposed for MRI reconstruction using CS, both in the k-space and image domains as well as using unrolled optimization methods. However, the drawback of these structures is that they are not fully utilizing the information from both domains (k-space and image). Herein, we propose a deep learning-based attention hybrid variational network that performs learning in both the k-space and image domain. We evaluate our method on a well-known open-source MRI dataset and a clinical MRI dataset of patients diagnosed with strokes from our institution to demonstrate the performance of our network. In addition to quantitative evaluation, we undertook a blinded comparison of image quality across networks performed by a subspecialty trained radiologist. Overall, we demonstrate that our network achieves a superior performance among others under multiple reconstruction tasks.

eess.IV

Bayesian Reconstruction of Magnetic Resonance Images using Gaussian Processes

A central goal of modern magnetic resonance imaging (MRI) is to reduce the time required to produce high-quality images. Efforts have included hardware and software innovations such as parallel imaging, compressed sensing, and deep learning-based reconstruction. Here, we propose and demonstrate a Bayesian method to build statistical libraries of magnetic resonance (MR) images in k-space and use these libraries to identify optimal subsampling paths and reconstruction processes. Specifically, we compute a multivariate normal distribution based upon Gaussian processes using a publicly available library of T1-weighted images of healthy brains. We combine this library with physics-informed envelope functions to only retain meaningful correlations in k-space. This covariance function is then used to select a series of ring-shaped subsampling paths using Bayesian optimization such that they optimally explore space while remaining practically realizable in commercial MRI systems. Combining optimized subsampling paths found for a range of images, we compute a generalized sampling path that, when used for novel images, produces superlative structural similarity and error in comparison to previously reported reconstruction processes (i.e. 96.3% structural similarity and <0.003 normalized mean squared error from sampling only 12.5% of the k-space data). Finally, we use this reconstruction process on pathological data without retraining to show that reconstructed images are clinically useful for stroke identification.

physics.med-ph

Auxetics-Inspired Tunable Metamaterials for Magnetic Resonance Imaging

Auxetics refers to structures or materials with a negative Poisson's ratio, thereby capable of exhibiting counter-intuitive behaviors. Herein, auxetic structures are exploited to design mechanically tunable metamaterials in both planar and hemispherical configurations operating at megahertz (MHz) frequencies, optimized for their application to magnetic resonance imaging (MRI). Specially, the reported tunable metamaterials are composed of arrays of inter-jointed unit cells featuring metallic helices, enabling auxetic patterns with a negative Poisson's ratio. The deployable deformation of the metamaterials yields an added degree of freedom with respect to frequency tunability through the resultant modification of the electromagnetic interactions between unit cells. The metamaterials are fabricated using 3D printing technology and a ~20 MHz frequency shift of the resonance mode is enabled during deformation. Experimental validation is performed in a clinical (3.0 Tesla) MRI, demonstrating that the metamaterials enable a marked boost in radiofrequency (RF) field strength under resonance matched conditions, ultimately yielding a dramatic increase in the signal-to-noise ratio (SNR) (~ 4.5X) of MRI. The tunable metamaterials presented herein offer a novel pathway towards the practical utilization of metamaterials in MRI, as well as a range of other emerging applications.

physics.med-ph