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Subhadip Ghosh

Publications and source records attributed to Subhadip Ghosh.

18 recordsLinked to original sources

NEMESIS: NEtlist-Driven Modeling and Equation Synthesis with Inversion-Aware SPICE Anchoring

This work presents NEMESIS, a multimodal framework for operational transconductance amplifier (OTA) design using large language models (LLMs). NEMESIS strikes a balance between fast, approximate analytical models vs. accurate, computationally expensive SPICE evaluations. Given an OTA netlist and schematic, NEMESIS first identifies circuit primitives and then generates progressively more accurate performance equations. The framework begins with equations retrieved from the prior invocations of NEMESIS to structurally similar OTAs, if available; otherwise, it uses the LLM to derive the initial equations directly from the circuit input. These equations are iteratively refined via a SPICE-based repair loop. In a commercial 65nm PDK, NEMESIS is demonstrated on five OTA topologies, producing SPICE-verified equations across biasing ranges with <7% average relative error and a post-convergence evaluation speedup of ~4622x over full SPICE-based evaluation.

cs.AR

COmPOSER: Circuit Optimization of mm-wave/RF circuits with Performance-Oriented Synthesis for Efficient Realizations

This work presents COmPOSER, an open-source, end-to-end framework for RF/mm-wave design automation that translates target specifications into optimized circuits with layouts. It unifies schematic synthesis, layout generation for actives and passives, and placement/routing, incorporating physics-based equations and machine-learning-driven electromagnetic models. Based on post-layout validation on multiple LNAs and PAs operating at up to 60GHz in a commercial 65nm process-kit, COmPOSER meets performance targets, comparable to expert manual designs, while delivering a 100-300x productivity gain. Github repo github[dot]com[slash]UMN-EDA[slash]COmPOSER

cs.AR

Spin Inertia as a Source of Topological Magnons: Chiral Edge States from Coupled Precession and Nutation

Spin inertia has been demonstrated to give rise to high-frequency nutational excitations beyond the conventional low-frequency precessional modes. Here, we demonstrate that the hybridization between precessional and nutational magnons may give rise to topological phenomena in the spin-wave spectrum. This hybridization requires the presence of interactions breaking angular-momentum conservation, such as the pseudodipolar interaction. We show on the example of a honeycomb ferromagnet how topological gaps open between the precessional and nutational bands that host chiral edge states in slab geometries. Our work establishes a theoretical foundation for exploring inertial spin dynamics as a new route to engineer topological phases in magnetic materials.

cond-mat.mtrl-sci

Engineering spin-wave spectrum via the magnetization inertia tensor

Magnetic inertial dynamics has recently been predicted and experimentally demonstrated in two-sublattice ferromagnets such as CoFeB and NiFe permalloy. In this work, we investigate the spin-wave spectrum of such systems by incorporating the complete magnetic inertia tensor. By decomposing the tensor into symmetric and antisymmetric components, we identify isotropic, anisotropic, and chiral contributions to magnetic inertia. Within linear spin-wave theory, we find that the spectrum comprises two precessional and two inertial magnon bands. Remarkably, the upper precessional band intersects the lower inertial band within the Brillouin zone. Both cross-sublattice and chiral components of the inertia tensor act as effective control parameters for tuning these magnonic band structures. Furthermore, we show that the inertial spin-wave spectrum becomes nonreciprocal along propagation directions where the Dzyaloshinskii-Moriya interaction is finite. Strikingly, a similar nonreciprocity can also arise purely from chiral inertia, even in the absence of Dzyaloshinskii-Moriya interaction. Our findings establish magnetic inertia as a new pathway to engineer nonreciprocal magnon transport and ultrafast spintronic functionalities.

cond-mat.mes-hall

Energy-efficient UAV movement and user-UAV association in multi-UAV networks

These days, unmanned aerial vehicle (UAV)-based millimeter wave (mmWave) communication systems have drawn a lot of attention due to the increasing demand for faster data rates. Given the susceptibility of mmWave signals to obstacles and high propagation loss of mmWaves, ensuring line-of-sight (LoS) connectivity is critical for maintaining robust and efficient communication. Furthermore, UAVs have limited power resource and limited capacity in terms of number of users it can serve. Most significantly different users have different delay requirements and they keep moving while interacting with the UAVs. In this paper, first, we have provided an efficient solution for the optimal movement of the UAVs, by taking into account the energy efficiency of the UAVs as well as the mobility and delay priority of the users. Next, we have proposed a greedy solution for the optimal user-UAV assignment. After that, the numerical results show how well the suggested solution performs in comparison to the current benchmarks in terms of delay suffered by the users, number of unserved users, and energy efficiency of the UAVs.

eess.SY

Accelerating OTA Circuit Design: Transistor Sizing Based on a Transformer Model and Precomputed Lookup Tables

Device sizing is crucial for meeting performance specifications in operational transconductance amplifiers (OTAs), and this work proposes an automated sizing framework based on a transformer model. The approach first leverages the driving-point signal flow graph (DP-SFG) to map an OTA circuit and its specifications into transformer-friendly sequential data. A specialized tokenization approach is applied to the sequential data to expedite the training of the transformer on a diverse range of OTA topologies, under multiple specifications. Under specific performance constraints, the trained transformer model is used to accurately predict DP-SFG parameters in the inference phase. The predicted DP-SFG parameters are then translated to transistor sizes using a precomputed look-up table-based approach inspired by the gm/Id methodology. In contrast to previous conventional or machine-learning-based methods, the proposed framework achieves significant improvements in both speed and computational efficiency by reducing the need for expensive SPICE simulations within the optimization loop; instead, almost all SPICE simulations are confined to the one-time training phase. The method is validated on a variety of unseen specifications, and the sizing solution demonstrates over 90% success in meeting specifications with just one SPICE simulation for validation, and 100% success with 3-5 additional SPICE simulations.

cs.AR

A Physics-Informed Context-Aware Approach for Anomaly Detection in Tele-driving Operations Under False Data Injection Attacks

Tele-operated driving (ToD) systems are special types of cyber-physical systems (CPSs) where the operator remotely controls the steering, acceleration, and braking actions of the vehicle. Malicious actors may inject false data in communication channels to manipulate the tele-operators driving commands to cause harm. Hence, protection of this communication is necessary for the safe operation of the target vehicle. However, according to the National Institute of Standards and Technology (NIST) cybersecurity framework, protection merely is not enough and the detection of an attack is necessary. Moreover, UN R155 mandates that security incidents across vehicle fleets be detected and logged. Thus, cyber-physical threats of ToD are modeled with an attack-centric approach in this paper. Then, an attack model with false data injection (FDI) on steering control commands is created from real vehicle data. The risk of this attack model is assessed for a last-mile delivery (LMD) application. Finally, a physics-informed context-aware anomaly detection system (PCADS) is proposed to detect such false injection attacks, and preliminary experimental results are presented to validate the model.

eess.SY

Theory of tensorial magnetic inertia in terahertz spin dynamics

Magnetic inertia has emerged as a possible way to manipulate ferromagnetic spins at a higher frequency e.g., THz. Theoretical treatments so far have considered the magnetic inertia as a scalar quantity. Here, we explore the magnetic inertial dynamics with a magnetic inertia tensor as macroscopic derivations predicted it to be a tensor. First, the inertia tensor has been decomposed into three terms: (a) scalar and isotropic inertia, (b) anisotropic and symmetric inertia tensor, (c) chiral and antisymmetric tensor. Further, we employ linear response theory to the inertial Landau-Lifshitz-Gilbert equation with the inertia tensor and calculate the effect of chiral and anisotropic inertia on ferromagnets, antiferromagnets, and ferrimagnets. It is established that the precession and nutation resonance frequencies decrease with scalar magnetic inertia. Our results suggest that the nutation resonance frequencies further reduce due to inertia tensor. However, the effective damping of the nutation resonance increases with the chiral and antisymmetric part of the inertia tensor. We show that the precession resonances remain unaffected, while the nutation resonances are modified with the chiral magnetic inertia.

cond-mat.mes-hall

Optical and structural properties of starch films formed on drying droplets of gelatinized starch solutions

We report the optical and structural properties of starch films formed on drying droplets of starch solutions on a flat substrate. The starch films formed after drying are circular in shape and have an azimuthally symmetric "M-shaped" height profile along their diameter. These films are found to be semi-crystalline in nature and transparent in visible light. Our experimental results show that these films are optically uniaxial at their center but biaxial away from the center. The variation of birefringence along the radial direction is studied for the films formed after drying droplets with different volumes and starch concentrations. The cryo-SEM studies on the drying droplets and the films reveal the micro-structures and the possible origin of birefringence of these films.

cond-mat.soft

Observation of banded spherulite in a pure compound by rhythmic growth

Banded spherulitic growth of crystal is observed in some materials with spherically symmetric growth front and periodic radial variation of birefringence. This variation of birefringence in quasi two dimensional geometry produces concentric interference colour bands when viewed through crossed polarisers. In most materials, the banded spherulites are found to be formed by radially oriented periodically twisted fibrillar crystallites. Here, we report the formation of banded spherulites due to the rhythmic growth of concentric crystallite-rich and crystallite-poor bands for a pure compound consisting of strongly polar rod like molecules. The compound exhibits coexistence of untwisted fibrillar crystallites and an amorphous phase in its most stable solid state. On sufficient supercooling of the sample from its melting point, the banded spherulites are formed with a periodic variation of composition of untwisted radially aligned fibrillar crystallites and an amorphous solid phase. We have developed a time dependent Ginzburg-Landau model to account for the observed banded spherulitic growth.

cond-mat.mtrl-sci

Pattern formation, localized and running pulsation on active spherical membranes

Active force generation by actin-myosin cortex coupled to the cell membrane allows the cell to deform, respond to the environment, and mediate cell motility and division. Several membrane-bound activator proteins move along it and couple to the membrane curvature. Besides, they can act as nucleating sites for the growth of filamentous actin. Actin polymerization can generate a local outward push on the membrane. Inward pull from the contractile actomyosin cortex can propagate along the membrane via actin filaments. We use coupled evolution of fields to perform linear stability analysis and numerical calculations. As activity overcomes the stabilizing factors such as surface tension and bending rigidity, the spherical membrane shows instability towards pattern formation, localized pulsation, and running pulsation between poles. We present our results in terms of phase diagrams and evolutions of the coupled fields. They have relevance for living cells and can be verified in experiments on artificial cell-like constructs.

cond-mat.soft

Filament-motor protein system under loading: instability and limit cycle oscillations

We consider the dynamics of a rigid filament in a motor protein assay under external loading. The motor proteins are modeled as active harmonic linkers with tail ends immobilized on a substrate. Their heads attach to the filament stochastically to extend along it, resulting in a force on the filament, before detaching. The rate of extension and detachment are load dependent. Here we formulate and characterize the governing dynamics in the mean field approximation using linear stability analysis, and direct numerical simulations of the motor proteins and filament. Under constant loading, the system shows transition from a stable configuration to instability towards detachment of the filament from motor proteins. Under elastic loading, we find emergence of stable limit cycle oscillations via a supercritical Hopf bifurcation with change in activity and the number of motor proteins. Numerical simulations of the system for large number of motor proteins show good agreement with the mean field predictions.

physics.bio-ph

Deconstructing the role of myosin contractility in force fluctuations within focal adhesions

Force fluctuations exhibited in focal adhesions (FAs) that connect a cell to its extracellular environment, point to the complex role of the underlying machinery that controls cell migration. To elucidate the explicit role of myosin motors in the temporal traction force oscillations, we vary the contractility of these motors in a dynamical model based on the molecular clutch hypothesis. As the contractility is lowered, effected both by changing the motor velocity and the rate of attachment/detachment, we show analytically in an experimentally relevant parameter space that the system goes from decaying oscillations to stable limit cycle oscillations through a supercritical Hopf bifurcation. As a function of motor activity and the number of clutches, the system exhibits a wide array of dynamical states. We corroborate our analytical results with stochastic simulations of the motor-clutch system. We obtain limit cycle oscillations in the parameter regime as predicted by our model. The frequency range of oscillations in the average clutch and motor deformation compares well with experimental results.

physics.bio-ph

Entanglement and weak interaction driven mobility of small molecules in polymer networks

Diffusive transport of small molecules within the internal structures of biological and synthetic material systems is complex because the crowded environment presents chemical and physical barriers to mobility. We explored this mobility using a synthetic experimental system of small dye molecules diffusing within a polymer network at short time scales. We find that the diffusion of inert molecules is inhibited by the presence of the polymers. Counter-intuitively, small, hydrophobic molecules display smaller reduction in mobility and also able to diffuse faster through the system by leveraging crowding specific parameters. We explained this phenomenon by developing a de novo model and using these results, we hypothesized that non-specific hydrophobic interactions between the molecules and polymer chains could localize the molecules into compartments of overlapped and entangled chains where they experience microviscosity, rather than macroviscosity. We introduced a characteristic interaction time parameter to quantitatively explain experimental results in the light of frictional effects and molecular interactions. Our model is in good agreement with the experimental results and allowed us to classify molecules into two different mobility categories solely based on interaction. By changing the surface group, polymer molecular weight, and by adding salt to the medium, we could further modulate the mobility and mean square displacements of interacting molecules. Our work has implications in understanding intracellular diffusive transport in microtubule networks and other systems with macromolecular crowding and could lead to transport enhancement in synthetic polymer systems.

cond-mat.soft

Critical Phenomena in Plasma Membrane Organization and Function

Lateral organization in the plane of the plasma membrane is an important driver of biological processes. The past dozen years have seen increasing experimental support for the notion that lipid organization plays an important role in modulating this heterogeneity. Various biophysical mechanisms rooted in the concept of liquid-liquid phase separation have been proposed to explain diverse experimental observations of heterogeneity in model and cell membranes, with distinct but overlapping applicability. In this review, we focus on evidence for and consequences of the hypothesis that the plasma membrane is poised near an equilibrium miscibility critical point. Critical phenomena explain certain features of the heterogeneity observed in cells and model systems, but also go beyond heterogeneity to predict other interesting phenomena, including responses to composition perturbations.

physics.bio-ph

Stabilization of overlapping biofilaments by passive crosslinkers

The formation, maintenance and reorganization of the cytoskeletal filament network is essential for a number of cellular processes. While the crucial role played by active forces generated by motor proteins has been studied extensively, only recently the importance of passive forces exerted by non-enzymatic crosslinkers has been realized. The interplay between active and passive proteins manifests itself, e.g., during cell division, where the spindle structure formed by overlapping microtubules is subject to both active sliding forces generated by crosslinking motor proteins and passive forces exerted by passive crosslinkers, such as Ase1 and PRC1. We propose a minimal model to describe the stability behaviour of a pair of anti-parallel overlapping microtubules resulting from the competition between active motors and passive crosslinkers. We obtain the stability diagram which characterizes the formation of stable overlap of the MT pair, identify the controlling biological parameters which determine their stability, and study the impact of mutual interactions between motors and passive crosslinkers on the stability of these overlapping filaments.

physics.bio-ph

Bidirectional motion of filaments: Role of motor proteins and passive cross linkers

In eukaryotic cells, motor proteins (MP) bind to cytoskeletal filaments and move along them in a directed manner generating active stresses. During cell division a spindle structure of overlapping antiparallel microtubules (MT) form whose stability and dynamics under the influence of MPs has been studied extensively. Although passive cross linkers (PCL) were known to provide structural stability to filamentous network, consequences of the interplay between ATP dependent active forces of MPs and passive entropic forces of PCLs on MT overlap remains largely unexplored. Here, we formulate and characterize a model to study this, using linear stability analysis and numerical integration. In presence of PCLs, we find dynamic phase transitions with changing activity exhibiting regimes of stable partial overlap with or without oscillations, instability towards complete overlap, and stable limit cycle oscillations that emerge via a supercritical Hopf bifurcation characterized by an oscillation frequency determined by the MP and PCL parameters. We show that the overlap dynamics and stability depend crucially on whether both the MTs of overlapping pair are movable or one is immobilized, having potential implications for in vivo and in vitro studies.

physics.bio-ph

Driven Transport on open filaments with inter-filament switching processes

We study a two filament driven lattice gas model with oppositely directed species of particles moving on two parallel filaments with filament switching processes and particle inflow and outflow at filament ends. The filament switching process is {\it correlated} such that particles switch filaments with finite probability only when oppositely directed particles meet on the same filament. This model mimics some of the coarse grained features observed in context of microtubule (MT) based intracellular transport, wherein cellular cargo loaded and off-loaded at filament ends are transported on multiple parallel microtubule (MT) filaments and can switch between the parallel microtubule filaments. We focus on a regime where the filaments are weakly coupled, such that filament switching rates scale inversely as the length of the filament. We find that the interplay (off)loading processes at the boundaries and the filament switching process leads to some distinctive features of the system. These features includes occurrence of variety of phases in the system with inhomogeneous density profiles including localized density shocks, density difference across the filaments and bidirectional current flows in the system. We analyze the system by developing a mean field (MF) theory and comparing the results obtained from the MF theory with the Monte Carlo (MC) simulations of the dynamics of the system. We find that the steady state density and current profiles of particles and the phase diagram obtained within the MF picture matches quite well with MC simulation results. These findings maybe useful for studying multi-filament intracellular transport.

cond-mat.soft