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Suyash Mishra

Publications and source records attributed to Suyash Mishra.

12 recordsLinked to original sources

Local verification cannot detect non-transportability: a cohomological theory of context preservation in agentic reasoning

Agentic AI systems routinely transport conclusions across biological, clinical and financial contexts, and the emerging safeguard is local verification: checking at each step that the entity is representable in the chosen tool, that parameters are compatible, and that outputs cohere with the plan. We prove this class of safeguard is structurally incomplete. Modelling a covering of context space by its nerve and evidence by a real-valued 1-cochain, an agent chaining evidence performs path integration: its conclusion is path-independent if and only if the cochain is exact, and disagreement between valid reasoning paths is exactly the holonomy of a first Cech cohomology class. Hodge decomposition partitions evidence conflict into a gradient part (calibration), a curl part (local inconsistency, visible at triple overlaps) and a harmonic part. Our central result is that no family of simplex-supported consistency checks can distinguish omega from omega+h for harmonic h, which nonetheless generates non-zero disagreement between valid paths; detection requires a statistic on a cycle basis. The resulting procedure, Ksetra, estimates by coboundary projection and gates abstention on the harmonic component, which we give a mechanism: it arises from effect modification combined with overlap-specific population composition, and vanishes to machine precision when effect modification is absent. The degrees of freedom of an evidence network partition into calibration, coherence and transport, yielding an exact F-test for the existence of a global claim; we quantify its distortion under unequal precision and supply the precision-whitened form that restores exactness. Foreign exchange, where the arbitrage-free null makes the cochain exactly a coboundary, serves as a calibration bench: the test is correctly sized, fires on loop arbitrage, and ignores triangular arbitrage.

cs.AI

YUKTI: From Natural-Language Situations to Robust, Verifiable Decisions An Uncertainty-Typed Proposition IR, Assumption-Robust Pareto Frontiers, and a Regret Certificate

Language models turn a worded situation into a numeric plan, and the dominant pipelines (NL4Opt, OptiMUS, ORLM, OR-LLM-Agent) commit to a single objective and point-valued coefficients, then solve once. For decisions that allocate real budget, effort, or clinical attention, that confidence is the failure mode: every objectified number is an assumption, and a plan optimal only if the guesses are exactly right is fragile -- mimicry of computation. YUKTI changes the target of autoformulation. Its representation is a typed-proposition graph whose relationships carry shape priors, coefficient uncertainty, and provenance. YUKTI routes each stage to an exact, nonlinear, or evolutionary solver; couples stages by a distributional Pareto hand-off; and introduces Assumption-Robust Pareto Frontiers (ARPF), resampling assumptions (including structural epsilon-contamination) to score how often each action survives (rho). We prove a bound making rho an exact factor of decision regret, add auditable traceability, and synthesize a benchmark-faithful data foundation when none exists (SRJANA). We validate three ways: under controlled misspecification the robust compromise cuts mean and tail regret by over 90% versus a naive point plan; on a regulated commercial decision we optimize inside a lawful action space and price the downside in euros; and on a real public dataset of 41,188 decisions an out-of-sample backtest beats the logged status quo by 34% and a naive point rule by 4% while reducing the optimizer's curse. The solvers are standard; we claim no benchmark-SOTA win. A head-to-head shows an LLM given the correct numbers, and single-objective optimization, both incur about 47x the held-out regret of YUKTI -- an LLM is a formulator, not a solver. Under long-range causal coupling, the forward hand-off becomes unsound, locating where it must become a backward-induction causal policy.

cs.AI

A Calculus of Discernment: Decision-Relevant Insight, Sequence Value, and Forgetting as Higher-Order Learning

In a world of generative AI, candidate insights are abundant; what is scarce is the capacity to discern which matter, to act on them in the right amount and order, and to forget the rest so the system can adapt. We argue these scarcities are governed by one object and build a framework around it. We define an insight strictly as a lever with an identified, measurable effect on an objective, and rank candidates by decision-relevance via the expected value of information rather than novelty. We show action carries an order, not only a size: under realistic belief dynamics, content "touches" are non-commuting operators, so a fixed plan delivered in different orders yields different outcomes, defining a sequence premium. We observe that the value of any lever is a shadow price, unifying pharmaceutical marketing, equity selection, and manufacturing as one leverage-discovery problem. Most speculatively, we propose APOHA, a theory in which forgetting is not the disposal of knowledge but the operator by which value is learned: the value of a retained item is the counterfactual cost of forgetting it, a learning system is the residue of maximal forgetting subject to preserved value, and higher-order value is the structure that survives repeated forgetting (a renormalisation-relevant invariant), with consolidation as its conjugate. We state the central open problem (a non-trivial attractor with a spectral gap) and test the forgetting theory: operationalising APOHA as an agent on a non-stationary obesity-treatment decision world over 30 seeds, adaptive forgetting cut cumulative decision-regret by 24-32% against never-forget and a fixed half-life, kept a ~6x smaller, cleaner memory, and converged stably; notably, blind forgetting was worse than never forgetting, so the benefit is specific to value-aware forgetting. A multi-disciplinary critique stress-tests the whole.

cs.GT

VCAO: Verifier-Centered Agentic Orchestration for Strategic OS Vulnerability Discovery

We formulate operating-system vulnerability discovery as a \emph{repeated Bayesian Stackelberg search game} in which a Large Reasoning Model (LRM) orchestrator allocates analysis budget across kernel files, functions, and attack paths while external verifiers -- static analyzers, fuzzers, and sanitizers -- provide evidence. At each round, the orchestrator selects a target component, an analysis method, and a time budget; observes tool outputs; updates Bayesian beliefs over latent vulnerability states; and re-solves the game to minimize the strategic attacker's expected payoff. We introduce \textsc{VCAO} (\textbf{V}erifier-\textbf{C}entered \textbf{A}gentic \textbf{O}rchestration), a six-layer architecture comprising surface mapping, intra-kernel attack-graph construction, game-theoretic file/function ranking, parallel executor agents, cascaded verification, and a safety governor. Our DOBSS-derived MILP allocates budget optimally across heterogeneous analysis tools under resource constraints, with formal $\tilde{O}(\sqrt{T})$ regret bounds from online Stackelberg learning. Experiments on five Linux kernel subsystems -- replaying 847 historical CVEs and running live discovery on upstream snapshots -- show that \textsc{VCAO} discovers $2.7\times$ more validated vulnerabilities per unit budget than coverage-only fuzzing, $1.9\times$ more than static-analysis-only baselines, and $1.4\times$ more than non-game-theoretic multi-agent pipelines, while reducing false-positive rates reaching human reviewers by 68\%. We release our simulation framework, synthetic attack-graph generator, and evaluation harness as open-source artifacts.

cs.GT

Personalization as a Game: Equilibrium-Guided Generative Modeling for Physician Behavior in Pharmaceutical Engagement

We present \textbf{EGPF} (Equilibrium-Guided Personalization Framework), a mathematically rigorous architecture unifying Bayesian game theory, category theory, information theory, and generative AI for hyper-personalized physician engagement in the pharmaceutical domain. Our framework models the pharma--physician interaction as an incomplete-information Bayesian game where physician behavioral types are inferred via functorial mappings from observational categories, equilibrium strategies guide content generation through large language models (LLMs), and information-theoretic feedback loops ensure adaptive recalibration. We formalize behavior composition through category-theoretic functors, natural transformations, and monoidal structures, enabling modular, composable physician archetypes that respect structural invariants under domain shift. We introduce a novel \textit{Rate-Distortion Equilibrium} (RDE) criterion that bounds the personalization--privacy tradeoff, an \textit{Evolutionary Game Dynamics} layer for population-level behavior modeling, a \textit{Mechanism Design} module for incentive-compatible engagement, and a \textit{Sheaf-Theoretic} extension for multi-scale behavioral consistency. We prove convergence of our iterative belief-update mechanism at rate $O(\frac{K\log K}{t \cdot C_{\min}})$ and establish finite-sample regret bounds. Extensive experiments on synthetic pharma datasets and a real-world HCP engagement pilot demonstrate a 34\% improvement in engagement prediction (AUC) and 28\% lift in content relevance scores compared to state-of-the-art methods.

cs.GT

Prism: An Evolutionary Memory Substrate for Multi-Agent Open-Ended Discovery

We introduce \prism{} (\textbf{P}robabilistic \textbf{R}etrieval with \textbf{I}nformation-\textbf{S}tratified \textbf{M}emory), an evolutionary memory substrate for multi-agent AI systems engaged in open-ended discovery. \prism{} unifies four independently developed paradigms -- layered file-based persistence, vector-augmented semantic memory, graph-structured relational memory, and multi-agent evolutionary search -- under a single decision-theoretic framework with eight interconnected subsystems. We make five contributions: (1)~an \emph{entropy-gated stratification} mechanism that assigns memories to a tri-partite hub (skills/notes/attempts) based on Shannon information content, with formal context-window utilization bounds; (2)~a \emph{causal memory graph} $\mathcal{G} = (V, E_r, E_c)$ with interventional edges and agent-attributed provenance; (3)~a \emph{Value-of-Information retrieval} policy with self-evolving strategy selection; (4)~a \emph{heartbeat-driven consolidation} controller with stagnation detection via optimal stopping theory; and (5)~a \emph{replicator-decay dynamics} framework that interprets memory confidence as evolutionary fitness, proving convergence to an Evolutionary Stable Memory Set (ESMS). On the LOCOMO benchmark, \prism{} achieves 88.1 LLM-as-a-Judge score (31.2\% over Mem0). On CORAL-style evolutionary optimization tasks, 4-agent \prism{} achieves 2.8$\times$ higher improvement rate than single-agent baselines.%

cs.AI

Are Two LLMs Better Than One? A Student-Teacher Dual-Head LLMs Architecture for Pharmaceutical Content Optimization

Large language models (LLMs) are increasingly used to create content in regulated domains such as pharmaceuticals, where outputs must be scientifically accurate and legally compliant. Manual quality control (QC) is slow, error prone, and can become a publication bottleneck. We introduce LRBTC, a modular LLM and vision language model (VLM) driven QC architecture covering Language, Regulatory, Brand, Technical, and Content Structure checks. LRBTC combines a Student-Teacher dual model architecture, human in the loop (HITL) workflow with waterfall rule filtering to enable scalable, verifiable content validation and optimization. On AIReg-Bench, our approach achieves 83.0% F1 and 97.5% recall, reducing missed violations by 5x compared with Gemini 2.5 Pro. On CSpelling, it improves mean accuracy by 26.7%. Error analysis further reveals that while current models are strong at detecting misspellings (92.5 recall), they fail to identify complex medical grammatical (25.0 recall) and punctuation (41.7 recall) errors, highlighting a key area for future work. This work provides a practical, plug and play solution for reliable, transparent quality control of content in high stakes, compliance critical industries. We also provide access to our Demo under MIT Licenses.

cs.LG

The Neurosymbolic Frontier of Nonuniform Ellipticity: Formalizing Sharp Schauder Theory via Topos-Theoretic Reasoning Models

This white paper presents a critical synthesis of the recent breakthrough in nonuniformly elliptic regularity theory and the burgeoning field of neurosymbolic large reasoning models (LRMs). We explore the resolution of the long-standing sharp growth rate conjecture in Schauder theory, achieved by Cristiana De Filippis and Giuseppe Mingione, which identifies the exact threshold $q/p < 1 + α/n$ for gradient Hölder continuity. Central to this mathematical achievement is the ``ghost equation'' methodology, a sophisticated auxiliary derivation that bypasses the non-differentiability of classical Euler-Lagrange systems. We propose that the next era of mathematical discovery lies in the integration of these pure analytical constructs with LRMs grounded in topos theory and formal verification frameworks such as Safe and Typed Chain-of-Thought (PC-CoT). By modeling the reasoning process as a categorical colimit in a slice topos, we demonstrate how LRMs can autonomously navigate the ``Dark Side'' of the calculus of variations, providing machine-checkable proofs for regularity bounds in complex, multi-phase physical systems.

cs.SC

Scaling Vision Language Models for Pharmaceutical Long Form Video Reasoning on Industrial GenAI Platform

Vision Language Models (VLMs) have shown strong performance on multimodal reasoning tasks, yet most evaluations focus on short videos and assume unconstrained computational resources. In industrial settings such as pharmaceutical content understanding, practitioners must process long-form videos under strict GPU, latency, and cost constraints, where many existing approaches fail to scale. In this work, we present an industrial GenAI framework that processes over 200,000 PDFs, 25,326 videos across eight formats (e.g., MP4, M4V, etc.), and 888 multilingual audio files in more than 20 languages. Our study makes three contributions: (i) an industrial large-scale architecture for multimodal reasoning in pharmaceutical domains; (ii) empirical analysis of over 40 VLMs on two leading benchmarks (Video-MME and MMBench) and proprietary dataset of 25,326 videos across 14 disease areas; and (iii) four findings relevant to long-form video reasoning: the role of multimodality, attention mechanism trade-offs, temporal reasoning limits, and challenges of video splitting under GPU constraints. Results show 3-8 times efficiency gains with SDPA attention on commodity GPUs, multimodality improving up to 8/12 task domains (especially length-dependent tasks), and clear bottlenecks in temporal alignment and keyframe detection across open- and closed-source VLMs. Rather than proposing a new "A+B" model, this paper characterizes practical limits, trade-offs, and failure patterns of current VLMs under realistic deployment constraints, and provide actionable guidance for both researchers and practitioners designing scalable multimodal systems for long-form video understanding in industrial domains.

cs.CV

From Understanding to Engagement: Personalized pharmacy Video Clips via Vision Language Models (VLMs)

Vision Language Models (VLMs) are poised to revolutionize the digital transformation of pharmacyceutical industry by enabling intelligent, scalable, and automated multi-modality content processing. Traditional manual annotation of heterogeneous data modalities (text, images, video, audio, and web links), is prone to inconsistencies, quality degradation, and inefficiencies in content utilization. The sheer volume of long video and audio data further exacerbates these challenges, (e.g. long clinical trial interviews and educational seminars). Here, we introduce a domain adapted Video to Video Clip Generation framework that integrates Audio Language Models (ALMs) and Vision Language Models (VLMs) to produce highlight clips. Our contributions are threefold: (i) a reproducible Cut & Merge algorithm with fade in/out and timestamp normalization, ensuring smooth transitions and audio/visual alignment; (ii) a personalization mechanism based on role definition and prompt injection for tailored outputs (marketing, training, regulatory); (iii) a cost efficient e2e pipeline strategy balancing ALM/VLM enhanced processing. Evaluations on Video MME benchmark (900) and our proprietary dataset of 16,159 pharmacy videos across 14 disease areas demonstrate 3 to 4 times speedup, 4 times cost reduction, and competitive clip quality. Beyond efficiency gains, we also report our methods improved clip coherence scores (0.348) and informativeness scores (0.721) over state of the art VLM baselines (e.g., Gemini 2.5 Pro), highlighting the potential of transparent, custom extractive, and compliance supporting video summarization for life sciences.

cs.CV

Finder: A Multimodal AI-Powered Search Framework for Pharmaceutical Data Retrieval

AI is transforming pharmaceutical search, where traditional systems struggle with multimodal content and manual curation. Finder is a scalable AI-powered framework that unifies retrieval across text, images, audio, and video using hybrid vector search, combining sparse lexical and dense semantic models. Its modular pipeline ingests diverse formats, enriches metadata, and stores content in a vector-native backend. Finder supports reasoning-aware natural language search, improving precision and contextual relevance. The system has processed over 291,400 documents, 31,070 videos, and 1,192 audio files in 98 languages. Techniques like hybrid fusion, chunking, and metadata-aware routing enable intelligent access across regulatory, research, and commercial domains.

cs.IR

A Sui Generis QA Approach using RoBERTa for Adverse Drug Event Identification

Extraction of adverse drug events from biomedical literature and other textual data is an important component to monitor drug-safety and this has attracted attention of many researchers in healthcare. Existing works are more pivoted around entity-relation extraction using bidirectional long short term memory networks (Bi-LSTM) which does not attain the best feature representations. In this paper, we introduce a question answering framework that exploits the robustness, masking and dynamic attention capabilities of RoBERTa by a technique of domain adaptation and attempt to overcome the aforementioned limitations. Our model outperforms the prior work by 9.53% F1-Score.

cs.CL