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Syed Muhammad Anwar

Publications and source records attributed to Syed Muhammad Anwar.

53 records · Page 3Linked to original sources

Development of a Modular Real-time Shared-control System for a Smart Wheelchair

In this paper, we propose a modular navigation system that can be mounted on a regular powered wheelchair to assist disabled children and the elderly with autonomous mobility and shared-control features. The lack of independent mobility drastically affects an individual's mental and physical health making them feel less self-reliant, especially children with Cerebral Palsy and limited cognitive skills. To address this problem, we propose a comparatively inexpensive and modular system that uses a stereo camera to perform tasks such as path planning, obstacle avoidance, and collision detection in environments with narrow corridors. We avoid any major changes to the hardware of the wheelchair for an easy installation by replacing wheel encoders with a stereo camera for visual odometry. An open source software package, the Real-Time Appearance Based Mapping package, running on top of the Robot Operating System (ROS) allows us to perform visual SLAM that allows mapping and localizing itself in the environment. The path planning is performed by the move base package provided by ROS, which quickly and efficiently computes the path trajectory for the wheelchair. In this work, we present the design and development of the system along with its significant functionalities. Further, we report experimental results from a Gazebo simulation and real-world scenarios to prove the effectiveness of our proposed system with a compact form factor and a single stereo camera.

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Motor imagery classification using EEG spectrograms

The loss of limb motion arising from damage to the spinal cord is a disability that could effect people while performing their day-to-day activities. The restoration of limb movement would enable people with spinal cord injury to interact with their environment more naturally and this is where a brain-computer interface (BCI) system could be beneficial. The detection of limb movement imagination (MI) could be significant for such a BCI, where the detected MI can guide the computer system. Using MI detection through electroencephalography (EEG), we can recognize the imagination of movement in a user and translate this into a physical movement. In this paper, we utilize pre-trained deep learning (DL) algorithms for the classification of imagined upper limb movements. We use a publicly available EEG dataset with data representing seven classes of limb movements. We compute the spectrograms of the time series EEG signal and use them as an input to the DL model for MI classification. Our novel approach for the classification of upper limb movements using pre-trained DL algorithms and spectrograms has achieved significantly improved results for seven movement classes. When compared with the recently proposed state-of-the-art methods, our algorithm achieved a significant average accuracy of 84.9% for classifying seven movements.

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SB-SSL: Slice-Based Self-Supervised Transformers for Knee Abnormality Classification from MRI

The availability of large scale data with high quality ground truth labels is a challenge when developing supervised machine learning solutions for healthcare domain. Although, the amount of digital data in clinical workflows is increasing, most of this data is distributed on clinical sites and protected to ensure patient privacy. Radiological readings and dealing with large-scale clinical data puts a significant burden on the available resources, and this is where machine learning and artificial intelligence play a pivotal role. Magnetic Resonance Imaging (MRI) for musculoskeletal (MSK) diagnosis is one example where the scans have a wealth of information, but require a significant amount of time for reading and labeling. Self-supervised learning (SSL) can be a solution for handling the lack of availability of ground truth labels, but generally requires a large amount of training data during the pretraining stage. Herein, we propose a slice-based self-supervised deep learning framework (SB-SSL), a novel slice-based paradigm for classifying abnormality using knee MRI scans. We show that for a limited number of cases (<1000), our proposed framework is capable to identify anterior cruciate ligament tear with an accuracy of 89.17% and an AUC of 0.954, outperforming state-of-the-art without usage of external data during pretraining. This demonstrates that our proposed framework is suited for SSL in the limited data regime.

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A Multimodal Perceived Stress Classification Framework using Wearable Physiological Sensors

Mental stress is a largely prevalent condition known to affect many people and could be a serious health concern. The quality of human life can be significantly improved if mental health is properly managed. Towards this, we propose a robust method for perceived stress classification, which is based on using multimodal data, acquired from forty subjects, including three (electroencephalography (EEG), galvanic skin response (GSR), and photoplethysmography (PPG)) physiological modalities. The data is acquired for three minutes duration in an open eyes condition. A perceived stress scale (PSS) questionnaire is used to record the stress of participants, which is then used to assign stress labels (two- and three classes). Time (four from GSR and PPG signals) and frequency (four from EEG signal) domain features are extracted. Among EEG based features, using a frequency band selection algorithm for selecting the optimum EEG frequency subband, the theta band was selected. Further, a wrapper-based method is used for optimal feature selection. Human stress level classification is performed using three different classifiers, which are fed with a fusion of the selected set of features from three modalities. A significant accuracy (95% for two classes, and 77.5% for three classes) was achieved using the multilayer perceptron classifier.

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M-Net with Bidirectional ConvLSTM for Cup and Disc Segmentation in Fundus Images

Glaucoma is a severe eye disease that is known to deteriorate optic never fibers, causing cup size to increase, which could result in permanent loss of vision. Glaucoma is the second leading cause of blindness after cataract, but glaucoma being more dangerous as it is not curable. Early diagnoses and treatment of glaucoma can help to slow the progression of glaucoma and its damages. For the detection of glaucoma, the Cup to Disc ratio (CDR) provides significant information. The CDR depends heavily on the accurate segmentation of cup and disc regions. In this paper, we have proposed a modified M-Net with bidirectional convolution long short-term memory (LSTM), based on joint cup and disc segmentation. The proposed network combines features of encoder and decoder, with bidirectional LSTM. Our proposed model segments cup and disc regions based on which the abnormalities in cup to disc ratio can be observed. The proposed model is tested on REFUGE2 data, where our model achieves a dice score of 0.92 for optic disc and an accuracy of 98.99% in segmenting cup and disc regions

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Deep Convolutional Neural Network based Classification of Alzheimer's Disease using MRI data

Alzheimer's disease (AD) is a progressive and incurable neurodegenerative disease which destroys brain cells and causes loss to patient's memory. An early detection can prevent the patient from further damage of the brain cells and hence avoid permanent memory loss. In past few years, various automatic tools and techniques have been proposed for diagnosis of AD. Several methods focus on fast, accurate and early detection of the disease to minimize the loss to patients mental health. Although machine learning and deep learning techniques have significantly improved medical imaging systems for AD by providing diagnostic performance close to human level. But the main problem faced during multi-class classification is the presence of highly correlated features in the brain structure. In this paper, we have proposed a smart and accurate way of diagnosing AD based on a two-dimensional deep convolutional neural network (2D-DCNN) using imbalanced three-dimensional MRI dataset. Experimental results on Alzheimer Disease Neuroimaging Initiative magnetic resonance imaging (MRI) dataset confirms that the proposed 2D-DCNN model is superior in terms of accuracy, efficiency, and robustness. The model classifies MRI into three categories: AD, mild cognitive impairment, and normal control: and has achieved 99.89% classification accuracy with imbalanced classes. The proposed model exhibits noticeable improvement in accuracy as compared to the state-fo-the-art methods.

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Semi-Supervised Deep Learning for Multi-Tissue Segmentation from Multi-Contrast MRI

Segmentation of thigh tissues (muscle, fat, inter-muscular adipose tissue (IMAT), bone, and bone marrow) from magnetic resonance imaging (MRI) scans is useful for clinical and research investigations in various conditions such as aging, diabetes mellitus, obesity, metabolic syndrome, and their associated comorbidities. Towards a fully automated, robust, and precise quantification of thigh tissues, herein we designed a novel semi-supervised segmentation algorithm based on deep network architectures. Built upon Tiramisu segmentation engine, our proposed deep networks use variational and specially designed targeted dropouts for faster and robust convergence, and utilize multi-contrast MRI scans as input data. In our experiments, we have used 150 scans from 50 distinct subjects from the Baltimore Longitudinal Study of Aging (BLSA). The proposed system made use of both labeled and unlabeled data with high efficacy for training, and outperformed the current state-of-the-art methods with dice scores of 97.52%, 94.61%, 80.14%, 95.93%, and 96.83% for muscle, fat, IMAT, bone, and bone marrow tissues, respectively. Our results indicate that the proposed system can be useful for clinical research studies where volumetric and distributional tissue quantification is pivotal and labeling is a significant issue. To the best of our knowledge, the proposed system is the first attempt at multi-tissue segmentation using a single end-to-end semi-supervised deep learning framework for multi-contrast thigh MRI scans.

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Variational Capsule Encoder

We propose a novel capsule network based variational encoder architecture, called Bayesian capsules (B-Caps), to modulate the mean and standard deviation of the sampling distribution in the latent space. We hypothesized that this approach can learn a better representation of features in the latent space than traditional approaches. Our hypothesis was tested by using the learned latent variables for image reconstruction task, where for MNIST and Fashion-MNIST datasets, different classes were separated successfully in the latent space using our proposed model. Our experimental results have shown improved reconstruction and classification performances for both datasets adding credence to our hypothesis. We also showed that by increasing the latent space dimension, the proposed B-Caps was able to learn a better representation when compared to the traditional variational auto-encoders (VAE). Hence our results indicate the strength of capsule networks in representation learning which has never been examined under the VAE settings before.

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Brain Tumor Survival Prediction using Radiomics Features

Surgery planning in patients diagnosed with brain tumor is dependent on their survival prognosis. A poor prognosis might demand for a more aggressive treatment and therapy plan, while a favorable prognosis might enable a less risky surgery plan. Thus, accurate survival prognosis is an important step in treatment planning. Recently, deep learning approaches have been used extensively for brain tumor segmentation followed by the use of deep features for prognosis. However, radiomics-based studies have shown more promise using engineered/hand-crafted features. In this paper, we propose a three-step approach for multi-class survival prognosis. In the first stage, we extract image slices corresponding to tumor regions from multiple magnetic resonance image modalities. We then extract radiomic features from these 2D slices. Finally, we train machine learning classifiers to perform the classification. We evaluate our proposed approach on the publicly available BraTS 2019 data and achieve an accuracy of 76.5% and precision of 74.3% using the random forest classifier, which to the best of our knowledge are the highest reported results yet. Further, we identify the most important features that contribute in improving the prediction.

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Deep Learning for Musculoskeletal Image Analysis

The diagnosis, prognosis, and treatment of patients with musculoskeletal (MSK) disorders require radiology imaging (using computed tomography, magnetic resonance imaging(MRI), and ultrasound) and their precise analysis by expert radiologists. Radiology scans can also help assessment of metabolic health, aging, and diabetes. This study presents how machinelearning, specifically deep learning methods, can be used for rapidand accurate image analysis of MRI scans, an unmet clinicalneed in MSK radiology. As a challenging example, we focus on automatic analysis of knee images from MRI scans and study machine learning classification of various abnormalities including meniscus and anterior cruciate ligament tears. Using widely used convolutional neural network (CNN) based architectures, we comparatively evaluated the knee abnormality classification performances of different neural network architectures under limited imaging data regime and compared single and multi-view imaging when classifying the abnormalities. Promising results indicated the potential use of multi-view deep learning based classification of MSK abnormalities in routine clinical assessment.

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A Survey on Recent Advancements for AI Enabled Radiomics in Neuro-Oncology

Artificial intelligence (AI) enabled radiomics has evolved immensely especially in the field of oncology. Radiomics provide assistancein diagnosis of cancer, planning of treatment strategy, and predictionof survival. Radiomics in neuro-oncology has progressed significantly inthe recent past. Deep learning has outperformed conventional machinelearning methods in most image-based applications. Convolutional neu-ral networks (CNNs) have seen some popularity in radiomics, since theydo not require hand-crafted features and can automatically extract fea-tures during the learning process. In this regard, it is observed that CNNbased radiomics could provide state-of-the-art results in neuro-oncology,similar to the recent success of such methods in a wide spectrum ofmedical image analysis applications. Herein we present a review of the most recent best practices and establish the future trends for AI enabled radiomics in neuro-oncology.

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Electroencephalography based Classification of Long-term Stress using Psychological Labeling

Stress research is a rapidly emerging area in thefield of electroencephalography (EEG) based signal processing.The use of EEG as an objective measure for cost effective andpersonalized stress management becomes important in particularsituations such as the non-availability of mental health facilities.In this study, long-term stress is classified using baseline EEGsignal recordings. The labelling for the stress and control groupsis performed using two methods (i) the perceived stress scalescore and (ii) expert evaluation. The frequency domain featuresare extracted from five-channel EEG recordings in addition tothe frontal and temporal alpha and beta asymmetries. The alphaasymmetry is computed from four channels and used as a feature.Feature selection is also performed using a t-test to identifystatistically significant features for both stress and control groups.We found that support vector machine is best suited to classifylong-term human stress when used with alpha asymmetry asa feature. It is observed that expert evaluation based labellingmethod has improved the classification accuracy up to 85.20%.Based on these results, it is concluded that alpha asymmetry maybe used as a potential bio-marker for stress classification, when labels are assigned using expert evaluation.

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Medical Image Analysis using Convolutional Neural Networks: A Review

The science of solving clinical problems by analyzing images generated in clinical practice is known as medical image analysis. The aim is to extract information in an effective and efficient manner for improved clinical diagnosis. The recent advances in the field of biomedical engineering has made medical image analysis one of the top research and development area. One of the reason for this advancement is the application of machine learning techniques for the analysis of medical images. Deep learning is successfully used as a tool for machine learning, where a neural network is capable of automatically learning features. This is in contrast to those methods where traditionally hand crafted features are used. The selection and calculation of these features is a challenging task. Among deep learning techniques, deep convolutional networks are actively used for the purpose of medical image analysis. This include application areas such as segmentation, abnormality detection, disease classification, computer aided diagnosis and retrieval. In this study, a comprehensive review of the current state-of-the-art in medical image analysis using deep convolutional networks is presented. The challenges and potential of these techniques are also highlighted.

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Classification of Perceived Human Stress using Physiological Signals

In this paper, we present an experimental study for the classification of perceived human stress using non-invasive physiological signals. These include electroencephalography (EEG), galvanic skin response (GSR), and photoplethysmography (PPG). We conducted experiments consisting of steps including data acquisition, feature extraction, and perceived human stress classification. The physiological data of $28$ participants are acquired in an open eye condition for a duration of three minutes. Four different features are extracted in time domain from EEG, GSR and PPG signals and classification is performed using multiple classifiers including support vector machine, the Naive Bayes, and multi-layer perceptron (MLP). The best classification accuracy of 75% is achieved by using MLP classifier. Our experimental results have shown that our proposed scheme outperforms existing perceived stress classification methods, where no stress inducers are used.

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Emotion Classification in Response to Tactile Enhanced Multimedia using Frequency Domain Features of Brain Signals

Tactile enhanced multimedia is generated by synchronizing traditional multimedia clips, to generate hot and cold air effect, with an electric heater and a fan. This objective is to give viewers a more realistic and immersing feel of the multimedia content. The response to this enhanced multimedia content (mulsemedia) is evaluated in terms of the appreciation/emotion by using human brain signals. We observe and record electroencephalography (EEG) data using a commercially available four channel MUSE headband. A total of 21 participants voluntarily participated in this study for EEG recordings. We extract frequency domain features from five different bands of each EEG channel. Four emotions namely: happy, relaxed, sad, and angry are classified using a support vector machine in response to the tactile enhanced multimedia. An increased accuracy of 76:19% is achieved when compared to 63:41% by using the time domain features. Our results show that the selected frequency domain features could be better suited for emotion classification in mulsemedia studies.

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Segmentation of Glioma Tumors in Brain Using Deep Convolutional Neural Network

Detection of brain tumor using a segmentation based approach is critical in cases, where survival of a subject depends on an accurate and timely clinical diagnosis. Gliomas are the most commonly found tumors having irregular shape and ambiguous boundaries, making them one of the hardest tumors to detect. The automation of brain tumor segmentation remains a challenging problem mainly due to significant variations in its structure. An automated brain tumor segmentation algorithm using deep convolutional neural network (DCNN) is presented in this paper. A patch based approach along with an inception module is used for training the deep network by extracting two co-centric patches of different sizes from the input images. Recent developments in deep neural networks such as drop-out, batch normalization, non-linear activation and inception module are used to build a new ILinear nexus architecture. The module overcomes the over-fitting problem arising due to scarcity of data using drop-out regularizer. Images are normalized and bias field corrected in the pre-processing step and then extracted patches are passed through a DCNN, which assigns an output label to the central pixel of each patch. Morphological operators are used for post-processing to remove small false positives around the edges. A two-phase weighted training method is introduced and evaluated using BRATS 2013 and BRATS 2015 datasets, where it improves the performance parameters of state-of-the-art techniques under similar settings.

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Medical Image Retrieval using Deep Convolutional Neural Network

With a widespread use of digital imaging data in hospitals, the size of medical image repositories is increasing rapidly. This causes difficulty in managing and querying these large databases leading to the need of content based medical image retrieval (CBMIR) systems. A major challenge in CBMIR systems is the semantic gap that exists between the low level visual information captured by imaging devices and high level semantic information perceived by human. The efficacy of such systems is more crucial in terms of feature representations that can characterize the high-level information completely. In this paper, we propose a framework of deep learning for CBMIR system by using deep Convolutional Neural Network (CNN) that is trained for classification of medical images. An intermodal dataset that contains twenty four classes and five modalities is used to train the network. The learned features and the classification results are used to retrieve medical images. For retrieval, best results are achieved when class based predictions are used. An average classification accuracy of 99.77% and a mean average precision of 0.69 is achieved for retrieval task. The proposed method is best suited to retrieve multimodal medical images for different body organs.

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