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T. G. Constandinou

Publications and source records attributed to T. G. Constandinou.

2 recordsLinked to original sources

Using Legacy Polysomnography Data to Train a Radar System to Quantify Sleep in Older Adults and People living with Dementia

Objective: Ultra-wideband radar technology offers a promising solution for unobtrusive and cost-effective in-home sleep monitoring. However, the limited availability of radar sleep data poses challenges in building robust models that generalize across diverse cohorts and environments. This study proposes a novel deep transfer learning framework to enhance sleep stage classification using radar data. Methods: An end-to-end neural network was developed to classify sleep stages based on nocturnal respiratory and motion signals. The network was trained using a combination of large-scale polysomnography (PSG) datasets and radar data. A domain adaptation approach employing adversarial learning was utilized to bridge the knowledge gap between PSG and radar signals. Validation was performed on a radar dataset of 47 older adults (mean age: 71.2), including 18 participants with prodromal or mild Alzheimer disease. Results: The proposed network structure achieves an accuracy of 79.5% with a Kappa value of 0.65 when classifying wakefulness, rapid eye movement, light sleep and deep sleep. Experimental results confirm that our deep transfer learning approach significantly enhances automatic sleep staging performance in the target domain. Conclusion: This method effectively addresses challenges associated with data variability and limited sample size, substantially improving the reliability of automatic sleep staging models, especially in contexts where radar data is limited. Significance: The findings underscore the viability of UWB radar as a nonintrusive, forward-looking sleep assessment tool that could significantly benefit care for older people and people with neurodegenerative disorders.

cs.LG

Simulating optical coherence tomography for observing nerve activity: a finite difference time domain bi-dimensional model

We present a finite difference time domain (FDTD) model for computation of A line scans in time domain optical coherence tomography (OCT). By simulating only the end of the two arms of the interferometer and computing the interference signal in post processing, it is possible to reduce the computational time required by the simulations and, thus, to simulate much bigger environments. Moreover, it is possible to simulate successive A lines and thus obtaining a cross section of the sample considered. In this paper we present the model applied to two different samples: a glass rod filled with water-sucrose solution at different concentrations and a peripheral nerve. This work demonstrates the feasibility of using OCT for non-invasive, direct optical monitoring of peripheral nerve activity, which is a long-sought goal of neuroscience.

physics.med-ph