Tadiwos Meaza | Searcharxiv

arXiv2026

Understanding the Performance Behaviors of End-to-End Protein Design Pipelines on GPUs

Recent computational advances enable protein design pipelines to run end-to-end on GPUs, yet their heterogeneous computational behaviors remain undercharacterized at the system level. We implement and profile a representative pipeline at both component and full-pipeline granularities across varying inputs and hyperparameters. Our characterization identifies generally low GPU utilization and high sensitivity to sequence length and sampling strategies. We outline future research directions based on these insights and release an open-source pipeline and profiling scripts to facilitate further studies.

cs.ET↗

arXiv2025

Déjà Vu: Efficient Video-Language Query Engine with Learning-based Inter-Frame Computation Reuse

Recently, Video-Language Models (VideoLMs) have demonstrated remarkable capabilities, offering significant potential for flexible and powerful video query systems. These models typically rely on Vision Transformers (ViTs), which process video frames individually to extract visual embeddings. However, generating embeddings for large-scale videos requires ViT inferencing across numerous frames, posing a major hurdle to real-world deployment and necessitating solutions for integration into scalable video data management systems. This paper introduces Déjà Vu, a video-language query engine that accelerates ViT-based VideoLMs by reusing computations across consecutive frames. At its core is ReuseViT, a modified ViT model specifically designed for VideoLM tasks, which learns to detect inter-frame reuse opportunities, striking an effective balance between accuracy and reuse. Although ReuseViT significantly reduces computation, these savings do not directly translate into performance gains on GPUs. To overcome this, Déjà Vu integrates memory-compute joint compaction techniques that convert the FLOP savings into tangible performance gains. Evaluations on three VideoLM tasks show that Déjà Vu accelerates embedding generation by up to a 2.64x within a 2% error bound, dramatically enhancing the practicality of VideoLMs for large-scale video analytics.

cs.DC↗