arXiv subjects

Tarini Kumar Dutta

Publications and source records attributed to Tarini Kumar Dutta.

4 recordsLinked to original sources

arXiv2026

A Mathematical Model for Chemotherapy, Immunotherapy and Virotherapy Treatments of Cancer

We continue our study of a model for cancer treatment, constructed in Dutta et. al., 2025, by adding Virotherapy to the Chemotherapy and Immunotherapy studied there. It is a dynamical system model for the spread of cancer in healthy tissue. It allows computer experiments of various combinations of the three modalities, which cannot be performed in the laboratory or experimentally. The novelty is the addition of Virotherapy. The analysis shows that the model solutions exist, are bounded, and nonnegative on each finite time interval, thus biologically feasible. A time-stepping algorithm is constructed and implemented, and computer simulations are presented. The simulations show the development of the disease under various treatment options, including a baseline case without treatment, cases for each of the three treatments separately, and some combinations of the three treatments. These simulations indicate that combinations of treatments are more effective. However, we do not consider any limitation or incompatibilities of the joint application of the three modalities, that may exist in practice. Once validated in the field, the model can be used to design treatment schedules of combinations of the three modalities for improved outcomes.

q-bio.OT↗

arXiv2023

Two predators one prey model that integrates the effect of supplementary food resources due to one predator's kleptoparasitism under the possibility of retribution by the other predator

In ecology, foraging requires animals to expend energy in order to obtain resources. The cost of foraging can be reduced through kleptoparasitism, the theft of a resource that another individual has expended effort to acquire. Thus, kleptoparasitism is one of the most significant feeding techniques in ecology. In this study, we investigate a two predator one prey paradigm in which one predator acts as a kleptoparasite and the other as a host. This research considers the post-kleptoparasitism scenario, which has received little attention in the literature. Parametric requirements for the existence as well as local and global stability of biologically viable equilibria have been proposed. The occurrences of various one parametric bifurcations, such as saddle-node bifurcation, transcritical bifurcation, and Hopf bifurcation, as well as two parametric bifurcations, such as Bautin bifurcation, are explored in depth. Relatively low growth rate of first predator induces a subcritical Hopf bifurcation although a supercritical Hopf bifurcation occurs at relatively high growth rate of first predator making coexistence of all three species possible. Some numerical simulations have been provided for the purpose of verifying our theoretical conclusions.

q-bio.PE↗

arXiv2023

Predator-prey dynamics pertaining to structuralizing predator species into three stages coupled with maturation delay owing to juvenile hunting

The predator-prey dynamic appertaining to two species is explored, wherein the predator species is structured into different stages. As evidenced from natural documentation, the immature predators possess the potential to predate albeit not as competently as the adults. Nevertheless, this potentiality is not acquired immediately after their incipience of life, hence, the immature stage is branched off into the infant stage, the stage with extensive reliance on the adults, and the juvenile stage, the stage with the potential to predate but not to procreate. In this paper, this inaugural concept is coupled with injuries in the juvenile stage as the repercussion of their incompetency in predating, thereby ensuing a delay in their maturation. With the incentive to investigate the ascendancy of these refinements over the whole system, stability analyses along with various bifurcation analyses around the equilibrium points of the system are corroborated. In addition to Hopf, transcritical, and saddle node bifurcations, the existence of Bogdanov-Takens point, cusp point, Bautin bifurcation point, bloom phenomenon, twice occurring Hopf bifurcation, and bi-stability phenomenon make the paper appreciably more rich and efficacious.

math.DS↗

arXiv2022

Stage structured prey-predator model incorporating mortal peril consequential to inefficiency and habitat complexity in juvenile hunting

Dynamic exploration for a predator-prey bio-system of two species with ratio-dependent functional response is carried out, where the capability to predate in both the stages of the predator, the juvenile and the matured, is taken into account. But, only the matured predators are inferred to be efficient in killing the prey without any negative repercussions. The mortality risks for the juvenile predators are attributable to the inefficiency rate of juveniles coupled with habitat complexity which is either in the form of anti-predator behavior of the prey taken with the aid of their habitat or in the form of a territorial generalist mesopredator. So as to avoid extinction of either of the species and to preserve the food chain of the ecological system, the results pertaining to the existence and stability of all the equilibrium points of the bio-system along with permanence, transcritical and Hopf bifurcation has been thoroughly studied. Corroboration of the results along with the dependence of the biosystem on some crucial parameters is done through numerical simulation. It is found that juvenile predators' inefficiency relative to the resistance confronted, plays a crucial role to control each species density of the ecosystem, as an intriguing limit cycle between the trivial and axial equilibriums of the proposed system along with the co-existing periodic point, because of some ineffeciency parametric value of the juvenile predator has been witnessed.

q-bio.PE↗