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Taylor Okonek

Publications and source records attributed to Taylor Okonek.

6 recordsLinked to original sources

A Survival Framework for Estimating Child Mortality Rates using Multiple Data Types

Child mortality is an important population health indicator. However, many countries lack high-quality vital registration to measure child mortality rates precisely and reliably over time. Research endeavors such as those by the United Nations Inter-agency Group for Child Mortality Estimation (UN IGME) and the Global Burden of Disease (GBD) study leverage statistical models and available data to estimate child survival summaries including neonatal, infant, and under-five mortality rates. UN IGME fits separate models for each age group and the GBD uses a multi-step modeling process. We propose a Bayesian survival framework to estimate temporal trends in the probability of survival as a function of age, up to the fifth birthday, with a single model. Our framework integrates all data types that are used by UN IGME: household surveys, vital registration, and other pre-processed mortality rates. We demonstrate that our framework is applicable to any country using log-logistic and piecewise-exponential survival functions, and discuss findings for four example countries with diverse data profiles: Kenya, Brazil, Estonia, and Syrian Arab Republic. Our model produces estimates of the three survival summaries that are in broad agreement with both the data and the UN IGME estimates, but in addition gives the complete survival curve.

stat.AP

Higher-Order Network Structure Inference: A Topological Approach to Network Selection

Thresholding--the pruning of nodes or edges based on their properties or weights--is an essential preprocessing tool for extracting interpretable structure from complex network data, yet existing methods face several key limitations. Threshold selection often relies on heuristic methods or trial and error due to large parameter spaces and unclear optimization criteria, leading to sensitivity where small parameter variations produce significant changes in network structure. Moreover, most approaches focus on pairwise relationships between nodes, overlooking critical higher-order interactions involving three or more nodes. We introduce a systematic thresholding algorithm that leverages topological data analysis to identify optimal network parameters by accounting for higher-order structural relationships. Our method uses persistent homology to compute the stability of homological features across the parameter space, identifying parameter choices that are robust to small variations while preserving meaningful topological structure. Hyperparameters allow users to specify minimum requirements for topological features, effectively constraining the parameter search to avoid spurious solutions. We demonstrate the approach with an application in the Science of Science, where networks of scientific concepts are extracted from research paper abstracts, and concepts are connected when they co-appear in the same abstract. The flexibility of our approach allows researchers to incorporate domain-specific constraints and extends beyond network thresholding to general parameterization problems in data analysis.

cs.SI

A Pseudo-likelihood Approach to Under-5 Mortality Estimation

Accurate and precise estimates of the under-5 mortality rate (U5MR) are an important health summary for countries. However, full survival curves allow us to better understand the pattern of mortality in children under five. Modern demographic methods for estimating a full mortality schedule for children have been developed for countries with good vital registration and reliable census data, but perform poorly in many low- and middle-income countries (LMICs). In these countries, the need to utilize nationally representative surveys to estimate the U5MR requires additional care to mitigate potential biases in survey data, acknowledge the survey design, and handle the usual characteristics of survival data, for example, censoring and truncation. In this paper, we develop parametric and non-parametric pseudo-likelihood approaches to estimating child mortality across calendar time from complex survey data. We show that the parametric approach is particularly useful in scenarios where data are sparse and parsimonious models allow efficient estimation. We compare a variety of parametric models to two existing methods for obtaining a full survival curve for children under the age of 5, and argue that a parametric pseudo-likelihood approach is advantageous in LMICs. We apply our proposed approaches to survey data from four LMICs.

stat.ME

A Computationally Efficient Approach to Fully Bayesian Benchmarking

In small area estimation, it is sometimes necessary to use model-based methods to produce estimates in areas with little or no data. In official statistics, we often require that some aggregate of small area estimates agree with a national estimate for internal consistency purposes. Enforcing this agreement is referred to as benchmarking, and while methods currently exist to perform benchmarking, few are ideal for applications with non-normal outcomes and benchmarks with uncertainty. Fully Bayesian benchmarking is a theoretically appealing approach insofar as we can obtain posterior distributions conditional on a benchmarking constraint. However, existing implementations may be computationally prohibitive. In this paper, we critically review benchmarking methods in the context of small area estimation in low- and middle-income countries with binary outcomes and uncertain benchmarks, and propose a novel approach in which an unbenchmarked method that produces area-level samples can be combined with a rejection sampler or Metropolis-Hastings algorithm to produce benchmarked posterior distributions in a computationally efficient way. To illustrate the flexibility and efficiency of our approach, we provide comparisons to an existing benchmarking approach in a simulation, and applications to HIV prevalence and under-5 mortality estimation. Code implementing our methodology is available in the R package stbench.

stat.ME

Small Area Estimation of Health Outcomes

Small area estimation (SAE) entails estimating characteristics of interest for domains, often geographical areas, in which there may be few or no samples available. SAE has a long history and a wide variety of methods have been suggested, from a bewildering range of philosophical standpoints. We describe design-based and model-based approaches and models that are specified at the area-level and at the unit-level, focusing on health applications and fully Bayesian spatial models. The use of auxiliary information is a key ingredient for successful inference when response data are sparse and we discuss a number of approaches that allow the inclusion of covariate data. SAE for HIV prevalence, using data collected from a Demographic Health Survey in Malawi in 2015-2016, is used to illustrate a number of techniques. The potential use of SAE techniques for outcomes related to COVID-19 is discussed.

stat.AP

Distributions of Matching Distances in Topological Data Analysis

In topological data analysis, we want to discern topological and geometric structure of data, and to understand whether or not certain features of data are significant as opposed to simply random noise. While progress has been made on statistical techniques for single-parameter persistence, the case of two-parameter persistence, which is highly desirable for real-world applications, has been less studied. This paper provides an accessible introduction to two-parameter persistent homology and presents results about matching distance between 2-D persistence modules obtained from families of point clouds. Results include observations of how differences in geometric structure of point clouds affect the matching distance between persistence modules. We offer these results as a starting point for the investigation of more complex data.

cs.CG