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Tekin Bicer

Publications and source records attributed to Tekin Bicer.

25 records · Page 2Linked to original sources

High-Performance Ptychographic Reconstruction with Federated Facilities

Beamlines at synchrotron light source facilities are powerful scientific instruments used to image samples and observe phenomena at high spatial and temporal resolutions. Typically, these facilities are equipped only with modest compute resources for the analysis of generated experimental datasets. However, high data rate experiments can easily generate data in volumes that take days (or even weeks) to process on those local resources. To address this challenge, we present a system that unifies leadership computing and experimental facilities by enabling the automated establishment of data analysis pipelines that extend from edge data acquisition systems at synchrotron beamlines to remote computing facilities; under the covers, our system uses Globus Auth authentication to minimize user interaction, funcX to run user-defined functions on supercomputers, and Globus Flows to define and execute workflows. We describe the application of this system to ptychography, an ultra-high-resolution coherent diffraction imaging technique that can produce 100s of gigabytes to terabytes in a single experiment. When deployed on the DGX A100 ThetaGPU cluster at the Argonne Leadership Computing Facility and a microscopy beamline at the Advanced Photon Source, our system performs analysis as an experiment progresses to provide timely feedback.

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Joint ptycho-tomography with deep generative priors

Joint ptycho-tomography is a powerful computational imaging framework to recover the refractive properties of a 3D object while relaxing the requirements for probe overlap that is common in conventional phase retrieval. We use an augmented Lagrangian scheme for formulating the constrained optimization problem and employ an alternating direction method of multipliers (ADMM) for the joint solution. ADMM allows the problem to be split into smaller and computationally more efficient subproblems: ptychographic phase retrieval, tomographic reconstruction, and regularization of the solution. We extend our ADMM framework with plug-and-play (PnP) denoisers by replacing the regularization subproblem with a general denoising operator based on machine learning. While the PnP framework enables integrating such learned priors as denoising operators, tuning of the denoiser prior remains challenging. To overcome this challenge, we propose a denoiser parameter to control the effect of the denoiser and to accelerate the solution. In our simulations, we demonstrate that our proposed framework with parameter tuning and learned priors generates high-quality reconstructions under limited and noisy measurement data.

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Scalable and accurate multi-GPU based image reconstruction of large-scale ptychography data

While the advances in synchrotron light sources, together with the development of focusing optics and detectors, allow nanoscale ptychographic imaging of materials and biological specimens, the corresponding experiments can yield terabyte-scale large volumes of data that can impose a heavy burden on the computing platform. While Graphical Processing Units (GPUs) provide high performance for such large-scale ptychography datasets, a single GPU is typically insufficient for analysis and reconstruction. Several existing works have considered leveraging multiple GPUs to accelerate the ptychographic reconstruction. However, they utilize only Message Passing Interface (MPI) to handle the communications between GPUs. It poses inefficiency for the configuration that has multiple GPUs in a single node, especially while processing a single large projection, since it provides no optimizations to handle the heterogeneous GPU interconnections containing both low-speed links, e.g., PCIe, and high-speed links, e.g., NVLink. In this paper, we provide a multi-GPU implementation that can effectively solve large-scale ptychographic reconstruction problem with optimized performance on intra-node multi-GPU. We focus on the conventional maximum-likelihood reconstruction problem using conjugate-gradient (CG) for the solution and propose a novel hybrid parallelization model to address the performance bottlenecks in CG solver. Accordingly, we develop a tool called PtyGer (Ptychographic GPU(multiple)-based reconstruction), implementing our hybrid parallelization model design. The comprehensive evaluation verifies that PtyGer can fully preserve the original algorithm's accuracy while achieving outstanding intra-node GPU scalability.

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Deep Learning-based Low-dose Tomography Reconstruction with Hybrid-dose Measurements

Synchrotron-based X-ray computed tomography is widely used for investigating inner structures of specimens at high spatial resolutions. However, potential beam damage to samples often limits the X-ray exposure during tomography experiments. Proposed strategies for eliminating beam damage also decrease reconstruction quality. Here we present a deep learning-based method to enhance low-dose tomography reconstruction via a hybrid-dose acquisition strategy composed of extremely sparse-view normal-dose projections and full-view low-dose projections. Corresponding image pairs are extracted from low-/normal-dose projections to train a deep convolutional neural network, which is then applied to enhance full-view noisy low-dose projections. Evaluation on two experimental datasets under different hybrid-dose acquisition conditions show significantly improved structural details and reduced noise levels compared to uniformly distributed acquisitions with the same number of total dosage. The resulting reconstructions also preserve more structural information than reconstructions processed with traditional analytical and regularization-based iterative reconstruction methods from uniform acquisitions. Our performance comparisons show that our implementation, HDrec, can perform denoising of a real-world experimental data 410x faster than the state-of-the-art Xlearn method while providing better quality. This framework can be applied to other tomographic or scanning based X-ray imaging techniques for enhanced analysis of dose-sensitive samples and has great potential for studying fast dynamic processes.

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Petascale XCT: 3D Image Reconstruction with Hierarchical Communications on Multi-GPU Nodes

X-ray computed tomography is a commonly used technique for noninvasive imaging at synchrotron facilities. Iterative tomographic reconstruction algorithms are often preferred for recovering high quality 3D volumetric images from 2D X-ray images, however, their use has been limited to small/medium datasets due to their computational requirements. In this paper, we propose a high-performance iterative reconstruction system for terabyte(s)-scale 3D volumes. Our design involves three novel optimizations: (1) optimization of (back)projection operators by extending the 2D memory-centric approach to 3D; (2) performing hierarchical communications by exploiting "fat-node" architecture with many GPUs; (3) utilization of mixed-precision types while preserving convergence rate and quality. We extensively evaluate the proposed optimizations and scaling on the Summit supercomputer. Our largest reconstruction is a mouse brain volume with 9Kx11Kx11K voxels, where the total reconstruction time is under three minutes using 24,576 GPUs, reaching 65 PFLOPS: 34% of Summit's peak performance.

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TomoGAN: Low-Dose Synchrotron X-Ray Tomography with Generative Adversarial Networks

Synchrotron-based x-ray tomography is a noninvasive imaging technique that allows for reconstructing the internal structure of materials at high spatial resolutions from tens of micrometers to a few nanometers. In order to resolve sample features at smaller length scales, however, a higher radiation dose is required. Therefore, the limitation on the achievable resolution is set primarily by noise at these length scales. We present \TOMOGAN{}, a denoising technique based on generative adversarial networks, for improving the quality of reconstructed images for low-dose imaging conditions. We evaluate our approach in two photon-budget-limited experimental conditions: (1) sufficient number of low-dose projections (based on Nyquist sampling), and (2) insufficient or limited number of high-dose projections. In both cases the angular sampling is assumed to be isotropic, and the photon budget throughout the experiment is fixed based on the maximum allowable radiation dose on the sample. Evaluation with both simulated and experimental datasets shows that our approach can significantly reduce noise in reconstructed images, improving the structural similarity score of simulation and experimental data from 0.18 to 0.9 and from 0.18 to 0.41, respectively. Furthermore, the quality of the reconstructed images with filtered back projection followed by our denoising approach exceeds that of reconstructions with the simultaneous iterative reconstruction technique, showing the computational superiority of our approach.

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Deep Learning Accelerated Light Source Experiments

Experimental protocols at synchrotron light sources typically process and validate data only after an experiment has completed, which can lead to undetected errors and cannot enable online steering. Real-time data analysis can enable both detection of, and recovery from, errors, and optimization of data acquisition. However, modern scientific instruments, such as detectors at synchrotron light sources, can generate data at GBs/sec rates. Data processing methods such as the widely used computational tomography usually require considerable computational resources, and yield poor quality reconstructions in the early stages of data acquisition when available views are sparse. We describe here how a deep convolutional neural network can be integrated into the real-time streaming tomography pipeline to enable better-quality images in the early stages of data acquisition. Compared with conventional streaming tomography processing, our method can significantly improve tomography image quality, deliver comparable images using only 32% of the data needed for conventional streaming processing, and save 68% experiment time for data acquisition.

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