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Thanh-an Pham

Publications and source records attributed to Thanh-an Pham.

9 recordsLinked to original sources

A Mini-Batch Quasi-Newton Proximal Method for Constrained Total-Variation Nonlinear Image Reconstruction

Over the years, computational imaging with accurate nonlinear physical models has garnered considerable interest due to its ability to achieve high-quality reconstructions. However, using such nonlinear models for reconstruction is computationally demanding. A popular choice for solving the corresponding inverse problems is the accelerated stochastic proximal method (ASPM), with the caveat that each iteration is still expensive. To overcome this issue, we propose a mini-batch quasi-Newton proximal method (BQNPM) tailored to image reconstruction problems with constrained total variation regularization. Compared to ASPM, BQNPM requires fewer iterations to converge. Moreover, we propose an efficient approach to compute a weighted proximal mapping at a cost similar to that of the proximal mapping in ASPM. We also analyze the convergence of BQNPM in the nonconvex setting. We assess the performance of BQNPM on three-dimensional inverse-scattering problems with linear and nonlinear physical models. Our results on simulated and real data demonstrate the effectiveness and efficiency of BQNPM, while also validating our theoretical analysis.

math.OC↗

Bayesian Inversion for Nonlinear Imaging Models using Deep Generative Priors

Most modern imaging systems incorporate a computational pipeline to infer the image of interest from acquired measurements. The Bayesian approach to solve such ill-posed inverse problems involves the characterization of the posterior distribution of the image. It depends on the model of the imaging system and on prior knowledge on the image of interest. In this work, we present a Bayesian reconstruction framework for nonlinear imaging models where we specify the prior knowledge on the image through a deep generative model. We develop a tractable posterior-sampling scheme based on the Metropolis-adjusted Langevin algorithm for the class of nonlinear inverse problems where the forward model has a neural-network-like structure. This class includes most practical imaging modalities. We introduce the notion of augmented deep generative priors in order to suitably handle the recovery of quantitative images.We illustrate the advantages of our framework by applying it to two nonlinear imaging modalities-phase retrieval and optical diffraction tomography.

cs.CV↗

Phase Retrieval: From Computational Imaging to Machine Learning

Phase retrieval consists in the recovery of a complex-valued signal from intensity-only measurements. As it pervades a broad variety of applications, many researchers have striven to develop phase-retrieval algorithms. Classical approaches involve techniques as varied as generic gradient-descent routines or specialized spectral methods, to name a few. Yet, the phase-recovery problem remains a challenge to this day. Recently, however, advances in machine learning have revitalized the study of phase retrieval in two ways: significant theoretical advances have emerged from the analogy between phase retrieval and single-layer neural networks; practical breakthroughs have been obtained thanks to deep-learning regularization. In this tutorial, we review phase retrieval under a unifying framework that encompasses classical and machine-learning methods. We focus on three key elements: applications, overview of recent reconstruction algorithms, and the latest theoretical results.

physics.optics↗

Mechanical Artifacts in Optical Projection Tomography: Classification and Automatic Calibration

Optical projection tomography (OPT) is a powerful tool for biomedical studies. It achieves 3D visualization of mesoscopic biological samples with high spatial resolution using conventional tomographic-reconstruction algorithms. However, various artifacts degrade the quality of the reconstructed images due to experimental imperfections in the OPT instruments. While many efforts have been made to characterize and correct for these artifacts, they focus on one specific type of artifacts, whereas a comprehensive catalog of all sorts of mechanical artifacts does not currently exist. In this work, we systematically document many mechanical artifacts. We rely on a 3D description of the imaging system that uses a set of angular and translational parameters. We provide a catalog of artifacts. It lists their cause, resulting effects, and existing correction methods. Then, we introduce an automatic calibration algorithm that is able to recover the unknown system parameters fed into the final 3D iterative reconstruction algorithm for a distortion-free volumetric image. Simulations with beads data and experimental results on a fluorescent textile fiber confirm that our algorithm successfully removes miscalibration artifacts in the reconstruction.

physics.optics↗

Diffraction Tomography with Helmholtz Equation: Efficient and Robust Multigrid-Based Solver

Diffraction tomography is a noninvasive technique that estimates the refractive indices of unknown objects and involves an inverse-scattering problem governed by the wave equation. Recent works have shown the benefit of nonlinear models of wave propagation that account for multiple scattering and reflections. In particular, the Lippmann-Schwinger~(LiS) model defines an inverse problem to simulate the wave propagation. Although accurate, this model is hard to solve when the samples are highly contrasted or have a large physical size. In this work, we introduce instead a Helmholtz-based nonlinear model for inverse scattering. To solve the corresponding inverse problem, we propose a robust and efficient multigrid-based solver. Moreover, we show that our method is a suitable alternative to the LiS model, especially for strongly scattering objects. Numerical experiments on simulated and real data demonstrate the effectiveness of the Helmholtz model, as well as the efficiency of the proposed multigrid method.

eess.IV↗

Optimal-transport-based metric for SMLM

We propose the use of Flat Metric to assess the performance of reconstruction methods for single-molecule localization microscopy (SMLM) in scenarios where the ground-truth is available. Flat Metric is intimately related to the concept of optimal transport between measures of different mass, providing solid mathematical foundations for SMLM evaluation and integrating both localization and detection performance. In this paper, we provide the foundations of Flat Metric and validate this measure by applying it to controlled synthetic examples and to data from the SMLM 2016 Challenge.

eess.IV↗

Robust Phase Unwrapping via Deep Image Prior for Quantitative Phase Imaging

Quantitative phase imaging (QPI) is an emerging label-free technique that produces images containing morphological and dynamical information without contrast agents. Unfortunately, the phase is wrapped in most imaging system. Phase unwrapping is the computational process that recovers a more informative image. It is particularly challenging with thick and complex samples such as organoids. Recent works that rely on supervised training show that deep learning is a powerful method to unwrap the phase; however, supervised approaches require large and representative datasets which are difficult to obtain for complex biological samples. Inspired by the concept of deep image priors, we propose a deep-learning-based method that does not need any training set. Our framework relies on an untrained convolutional neural network to accurately unwrap the phase while ensuring the consistency of the measurements. We experimentally demonstrate that the proposed method faithfully recovers the phase of complex samples on both real and simulated data. Our work paves the way to reliable phase imaging of thick and complex samples with QPI.

eess.IV↗

Three-Dimensional Optical Diffraction Tomography with Lippmann-Schwinger Model

A broad class of imaging modalities involve the resolution of an inverse-scattering problem. Among them, three-dimensional optical diffraction tomography (ODT) comes with its own challenges. These include a limited range of views, a large size of the sample with respect to the illumination wavelength, and optical aberrations that are inherent to the system itself. In this work, we present an accurate and efficient implementation of the forward model. It relies on the exact (nonlinear) Lippmann-Schwinger equation. We address several crucial issues such as the discretization of the Green function, the computation of the far field, and the estimation of the incident field. We then deploy this model in a regularized variational-reconstruction framework and show on both simulated and real data that it leads to substantially better reconstructions than the approximate models that are traditionally used in ODT.

eess.IV↗

Pocket Guide to Solve Inverse Problems with GlobalBioIm

GlobalBioIm is an open-source MATLAB library for solving inverse problems. The library capitalizes on the strong commonalities between forward models to standardize the resolution of a wide range of imaging inverse problems. Endowed with an operator-algebra mechanism, GlobalBioIm allows one to easily solve inverse problems by combining elementary modules in a lego-like fashion. This user-friendly toolbox gives access to cutting-edge reconstruction algorithms, while its high modularity makes it easily extensible to new modalities and novel reconstruction methods. We expect GlobalBioIm to respond to the needs of imaging scientists looking for reliable and easy-to-use computational tools for solving their inverse problems. In this paper, we present in detail the structure and main features of the library. We also illustrate its flexibility with examples from multichannel deconvolution microscopy.

cs.MS↗