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Thijs Varkevisser

Publications and source records attributed to Thijs Varkevisser.

2 recordsLinked to original sources

Inelastic spreading of viscoelastic drops

When a liquid drop impacts a solid surface, rebound and splashing are known to be suppressed by additives that induce elastic effects; however, the influence of elasticity on the maximum spreading radius remains debated. The difficulty lies in isolating elastic resistance from the enhanced spreading caused by viscous shear thinning. Here, we experimentally decouple these effects by investigating Boger fluid drops (constant-viscosity solutions with high elasticity) of polyethylene oxide (PEO) and polyacrylamide (PAAM). We demonstrate that elastic properties do not alter the maximum spreading ratio, even at high concentrations up to 1000 ppm. We formulate an energy balance that accounts for the inertial, capillary, viscous, and elastic contributions, and yields a dimensionless criterion ($Γ$) that estimates the degree of elastic effects. We show that $Γ\ll 1$ for all impact conditions tested, demonstrating that elastic effects are energetically negligible during droplet spreading, opposite to what Weissenberg and Deborah numbers would predict.

physics.flu-dyn

Wrapping pathways of anisotropic dumbbell particles by giant unilamellar vesicles

Endocytosis is a key cellular process involved in the uptake of nutrients, pathogens or the diagnosis and therapy of diseases. Most studies have focused on spherical objects, whereas biologically relevant shapes can be highly anisotropic. In this letter, we use an experimental model system based on Giant Unilamellar Vesicles (GUVs) and dumbbell-shaped colloidal particles to mimic and investigate the first stage of the passive endocytic process: engulfment of an anisotropic object by the membrane. Our model has specific ligand-receptor interactions realized by mobile receptors on the vesicles and immobile ligands on the particles. Through a series of experiments, theory and molecular dynamics simulations, we quantify the wrapping process of anisotropic dumbbells by GUVs and identify distinct stages of the wrapping pathway. We find that the strong curvature variation in the neck of the dumbbell as well as membrane tension are crucial in determining both the speed of wrapping and the final states.

cond-mat.soft