arXiv subjects

Thomas Lai

Publications and source records attributed to Thomas Lai.

13 recordsLinked to original sources

arXiv2026

Foundation Models for Epileptogenic Zone Identification in Drug-Resistant Epilepsy

Accurate identification of the epileptogenic zone (EZ) is essential for seizure freedom after resective surgery in drug-resistant epilepsy, yet seizure freedom rates remain below 50%. We developed EpiiSLM, a dual foundation model system for EZ identification with stereo-electroencephalography (sEEG), by training a signal foundation model on 104,990 minutes of sEEG recordings from the Montreal Neurological Institute & Hospital, while leveraging all recordings regardless of surgical outcome and anchoring EZ biomarker extraction on non-epileptic signals. A language foundation model then integrates sEEG-derived outputs with multimodal clinical information to produce interpretable predictions. Under leave-one-patient-out evaluation, EpiiSLM achieved 0.978 contact-level positive predictive value (PPV), outperforming the seizure onset zone(SOZ)-as-EZ baseline by 15.1% (p < 0.05), and 100% region-level accuracy; on an external dataset, EpiiSLM achieved 0.857 contact-level PPV. EpiiSLM requires only one night of interictal sleep data, suggesting potential to reduce invasive sEEG monitoring duration and improve surgical outcomes.

cs.LG↗

arXiv2025

Probing the Physics of Dusty Outflows through Complex Organic Molecules in the Early Universe

Galaxy-scale outflows are of critical importance for galaxy formation and evolution. Dust grains are the main sites for the formation of molecules needed for star formation but are also important for the acceleration of outflows that can remove the gas reservoir critical for stellar mass growth. Using the MIRI medium-resolution integral field spectrograph aboard the James Webb Space Telescope (JWST), we detect the 3.28 $\mu$m aromatic and the 3.4 $\mu$m aliphatic hydrocarbon dust features in absorption in a redshift 4.601 hot dust-obscured galaxy, blue-shifted by $\Delta$V=$-5250^{+276}_{-339}$ kms$^{-1}$ from the systemic redshift of the galaxy. The extremely high velocity of the dust indicates that the wind was accelerated by radiation pressure from the central quasar. These results pave a novel way for probing the physics of dusty outflows in active galaxies at early cosmic time.

astro-ph.GA↗

arXiv2025

A JWST MIRI LRS Survey of 37 Massive Star-Forming Galaxies and AGN at Cosmic Noon -- Overview and First Results

We present a large spectroscopic survey with \textit{JWST}'s Mid-Infrared Instrument (MIRI) Low Resolution Spectrometer (LRS) targeting $37$ infrared-bright galaxies between $z=0.65-2.46$ with infrared luminosities $\log L_{\rm IR}/L_\odot>11.5$ and $\log M_*/M_\odot=10-11.5$. Targets were taken from a \textit{Spitzer} $24\,\mu$m-selected sample with archival spectroscopy from the Infrared Spectrograph (IRS) and include a mix of star-forming galaxies and dust-obscured AGN. By combining IRS with the increased sensitivity of LRS, we expand the range of spectral features observed between $5-30\,\mu$m for every galaxy in our sample. In this paper, we outline the sample selection, \textit{JWST} data reduction, 1D spectral extraction, and polycyclic aromatic hydrocarbon (PAH) feature measurements from $\lambda_{rest}=3.3-11.2\,\mu$m. In the \textit{JWST} spectra, we detect PAH emission features at $3.3-5.3\,\mu$m, as well as Paschen and Brackett lines. The $3.3\,\mu$m feature can be as bright as $1\%$ of the $8-1000\,\mu$m infrared luminosity and exhibits a tight correlation with the dust-obscured star-formation rate. We detect absorption features from CO gas, CO$_2$ ice, H$_2$O ice, and aliphatic dust. From the joint \textit{JWST} and \textit{Spitzer} analysis we find that the $11.3/3.3\,\mu$m PAH ratios are on-average three times higher than that of local luminous, infrared galaxies. This is interpreted as evidence that the PAH grains are larger at $z\sim1-2$. The size distribution may be affected by coagulation of grains due to high gas densities and low temperatures. These conditions are supported by the observation of strong water ice absorption at $3.05\,\mu$m, and can lower stellar radiative feedback as large PAHs transmit less energy per photon into the interstellar medium.

astro-ph.GA↗

arXiv2025

Shockingly Effective: Cluster Winds as Engines of Feedback in Starburst Galaxy VV 114

We present high-resolution Keck Cosmic Web Imager (KCWI) and MUSE IFU spectroscopy of VV 114, a local infrared-luminous merger undergoing a vigorous starburst and showing evidence of galactic-scale feedback. The high-resolution data allow for spectral deblending of the optical emission lines and reveal a broad emission line component ($\sigma_{\rm{broad}} \sim$~100--300 km s$^{-1}$) with line ratios and kinematics consistent with a mixture of ionization by stars and radiative shocks. The shock fraction (percent ionization due to shocks) in the high velocity gas is anticorrelated with projected surface number density of resolved star clusters, and we find radial density profiles around clusters are well fit by models of adiabatically expanding cluster winds driven by massive stellar winds and supernovae (SNe). The total kinetic power estimated from the cluster wind models matches the wind+SNe mechanical energy deposition rate estimated from the soft band X-ray luminosity, indicating that at least 70\% of the shock luminosity in the galaxy is driven by the star clusters. \emph{Hubble Space Telescope} narrow band near-infrared imaging reveals embedded shocks in the dust-buried infrared nucleus of VV 114E. Most of the shocked gas is blueshifted with respect to the quiescent medium, and there is a close spatial correspondence between the shock map and the \emph{Chandra} soft band X-ray image, implying the presence of a galactic superwind. The energy budget of the superwind is in close agreement with the total kinetic power of the cluster winds, confirming the superwind is driven by the starburst.

astro-ph.GA↗

arXiv2025

The Potential of the SPHEREx Mission for Characterizing Polycyclic Aromatic Hydrocarbon 3.3 {\mu}m Emission in Nearby Galaxies

Together with gas, stars, and supermassive black holes, dust is crucial in stellar and galaxy evolution. Hence, understanding galaxies' dust properties across cosmic time is critical to studying their evolution. In addition to photometric constraints on the absorption of blue light and its reemission at infrared wavelengths, dust grain properties can be explored spectroscopically via polycyclic aromatic hydrocarbon (PAH) emission bands in the mid-IR. The new SPHEREx space telescope conducts an all-sky spectrophotometric survey of stars and galaxies at wavelengths of 0.75-5$\,\mu$m, making it ideal for studying the widespread presence of the 3.3$\,\mu$m PAH emission across galaxy populations out to z ~ 0.4. In this paper, we simulated galaxy spectra to investigate SPHEREx's capability to study PAH emission in such galaxies. We find that for the all-sky survey the PAH 3.3$\,\mu$m emission band flux can be measured to 30% accuracy at $\log(\rm M/{\rm M_\odot})>9.5$ and star formation rate (SFR) $> 1\,{\rm M_\odot\,yr^{-1}}$ at $z=0.1$, $\log(\rm M/{\rm M_\odot}) > 10.5$ and ${\rm SFR} > 10\,{\rm M_\odot\,yr^{-1}}$ at $z=0.2-0.3$, and $\log(\rm M/{\rm M_\odot})>11$ and ${\rm SFR} > 100\,{\rm M_\odot\,yr^{-1}}$ at $z=0.4$. For deep SPHEREx fields, a factor of ~10 deeper sensitivity limits can be reached. Overall, SPHEREx will enable the measurement of the 3.3$\,\mu$m PAH band emission in several hundred thousand galaxies across the sky, providing a population study of the smallest dust grains ("nano grains") and radiation properties in massive galaxies in the nearby Universe.

astro-ph.GA↗

arXiv2025

Halfway to the Peak: ice absorption bands at $z\approx0.5$ with JWST MIRI/MRS

This paper presents the first combined detections of CO$_2$, CO, XCN and water ices beyond the local Universe. We find gas-phase CO in addition to the solid phase CO. Our source, SSTXFLS J172458.3+591545, is a $z=0.494$ star-forming galaxy which also hosts a deeply obscured AGN. The profiles of its ice features are consistent with those of other Galactic and local galaxy sources and the implied ice mantle composition is similar to that of even more obscured sources. The ice features indicate the presence of a compact nucleus in our galaxy and allow us to place constraints on its density and temperature ($n>10^5$cm$^{-3}$ and $T=20-90K$). We infer the visual extinction towards this nucleus to be $A_V\approx6-7$. An observed plot of $\tau_{Si}$ vs. $\tau_{CO2}/\tau_{Si}$ can be viewed as a probe for both the total dustiness of a system as well as the clumpiness of the dust along the line of sight. This paper highlights the potential of using {\sl JWST} MIRI spectra to study the dust composition and geometric distribution of sources beyond the local Universe.

astro-ph.GA↗

arXiv2024

GOALS-JWST: Constraining the Emergence Timescale for Massive Star Clusters in NGC 3256

We present the results of a James Webb Space Telescope (JWST) NIRCam and NIRSpec investigation into the young massive star cluster (YMC) population of NGC 3256, the most cluster-rich luminous infrared galaxy (LIRG) in the Great Observatories All Sky LIRG Survey. We detect 3061 compact YMC candidates with a $S/N \geq 3$ at F150W, F200W, and F335M. Based on yggdrasil stellar population models, we identify 116/3061 sources with F150W - F200W $> 0.47$ and F200W - F355M $> -1.37$ colors suggesting they are young (t $\leq 5$ Myr), dusty ($A_{V} = 5 - 15$), and massive ($M_{\odot} > 10^{5}$). This increases the sample of dust-enshrouded YMCs detected in this system by an order of magnitude relative to previous HST studies. With NIRSpec IFU pointings centered on the northern and southern nucleus, we extract the Pa$\alpha$ and 3.3$\mu$m PAH equivalent widths for 8 bright and isolated YMCs. Variations in both the F200W - F335M color and 3.3$\mu$m PAH emission with the Pa$\alpha$ line strength suggest a rapid dust clearing ($< 3 - 4$ Myr) for the emerging YMCs in the nuclei of NGC 3256. Finally, with both the age and dust emission accurately measured we use yggdrasil to derive the color excess (E(B - V)) for all 8 YMCs. We demonstrate that YMCs with strong 3.3$\mu$m PAH emission (F200W - F335M $> 0$) correspond to sources with E(B - V) $> 3$, which are typically missed in UV-optical studies. This underscores the importance of deep near-infrared imaging for finding and characterizing these very young and dust-embedded sources.

astro-ph.GA↗

arXiv2023

Open-Set Multivariate Time-Series Anomaly Detection

Numerous methods for time-series anomaly detection (TSAD) have emerged in recent years, most of which are unsupervised and assume that only normal samples are available during the training phase, due to the challenge of obtaining abnormal data in real-world scenarios. Still, limited samples of abnormal data are often available, albeit they are far from representative of all possible anomalies. Supervised methods can be utilized to classify normal and seen anomalies, but they tend to overfit to the seen anomalies present during training, hence, they fail to generalize to unseen anomalies. We propose the first algorithm to address the open-set TSAD problem, called Multivariate Open-Set Time-Series Anomaly Detector (MOSAD), that leverages only a few shots of labeled anomalies during the training phase in order to achieve superior anomaly detection performance compared to both supervised and unsupervised TSAD algorithms. MOSAD is a novel multi-head TSAD framework with a shared representation space and specialized heads, including the Generative head, the Discriminative head, and the Anomaly-Aware Contrastive head. The latter produces a superior representation space for anomaly detection compared to conventional supervised contrastive learning. Extensive experiments on three real-world datasets establish MOSAD as a new state-of-the-art in the TSAD field.

cs.LG↗

arXiv2022

GOALS-JWST: Revealing the Buried Star Clusters in the Luminous Infrared Galaxy VV 114

We present the results of a {\it James Webb Space Telescope} NIRCam investigation into the young massive star cluster (YMC) population in the luminous infrared galaxy VV 114. We identify 374 compact YMC candidates with a $S/N \geq 3$, 5, and 5 at F150W, F200W, and F356W respectively. A direct comparison with our {\it HST} cluster catalog reveals that $\sim 20\%$ of these sources are undetected at optical wavelengths. Based on {\it yggdrasil} stellar population models, we identify 17 YMC candidates in our {\it JWST} imaging alone with F150W-F200W and F200W-F356W colors suggesting they are all very young, dusty ($A_{V} = 5 - 15$), and massive ($10^{5.8} < M_{\odot} < 10^{6.1}$). The discovery of these `hidden' sources, many of which are found in the `overlap' region between the two nuclei, quadruples the number of $t < 3$ Myr clusters, and nearly doubles the number of $t < 6$ Myr clusters detected in VV 114. Now extending the cluster age distribution ($dN/d\tau \propto \tau^{\gamma}$) to the youngest ages, we find a slope of $\gamma = -1.30 \pm 0.39$ for $10^{6} < \tau (\mathrm{yr}) < 10^{7}$, which is consistent with the previously determined value from $10^{7} < \tau (\mathrm{yr}) < 10^{8.5}$, and confirms that VV 114 has a steep age distribution slope for all massive star clusters across the entire range of cluster ages observed. Finally, the consistency between our {\it JWST}- and {\it HST}-derived age distribution slopes indicates that the balance between cluster formation and destruction has not been significantly altered in VV 114 over the last 0.5 Gyr.

astro-ph.GA↗

arXiv2022

GOALS-JWST: NIRCam and MIRI Imaging of the Circumnuclear Starburst Ring in NGC 7469

We present James Webb Space Telescope (JWST) imaging of NGC 7469 with the Near-Infrared Camera (NIRCam) and the Mid-InfraRed Instrument (MIRI). NGC 7469 is a nearby, $z=0.01627$, luminous infrared galaxy (LIRG) that hosts both a Seyfert Type-1.5 nucleus and a circumnuclear starburst ring with a radius of $\sim$0.5 kpc. The new near-infrared (NIR) JWST imaging reveals 66 star-forming regions, 37 of which were not detected by HST observations. Twenty-eight of the 37 sources have very red NIR colors that indicate obscurations up to A$_{\rm{v}}\sim7$ and a contribution of at least 25$\%$ from hot dust emission to the 4.4$\mu$m band. Their NIR colors are also consistent with young ($<$5 Myr) stellar populations and more than half of them are coincident with the MIR emission peaks. These younger, dusty star-forming regions account for $\sim$6$\%$ and $\sim$17$\%$ of the total 1.5$\mu$m and 4.4$\mu$m luminosity of the starburst ring, respectively. Thanks to JWST, we find a significant number of young dusty sources that were previously unseen due to dust extinction. The newly identified 28 young sources are a significant increase compared to the number of HST-detected young sources (4-5). This makes the total percentage of the young population rise from $\sim$15$\%$ to 48$\%$. These results illustrate the effectiveness of JWST in identifying and characterizing previously hidden star formation in the densest star-forming environments around AGN.

astro-ph.GA↗

arXiv2022

GOALS-JWST: Resolving the Circumnuclear Gas Dynamics in NGC 7469 in the Mid-Infrared

The nearby, luminous infrared galaxy (LIRG) NGC 7469 hosts a Seyfert nucleus with a circumnuclear star-forming ring and is thus the ideal local laboratory for investigating the starburst--AGN connection in detail. We present integral-field observations of the central 1.3 kpc region in NGC 7469 obtained with the JWST Mid-InfraRed Instrument. Molecular and ionized gas distributions and kinematics at a resolution of {\sim}100 pc over the 4.9 - 7.6{\mu}m region are examined to study gas dynamics influenced by the central AGN. The low-ionization [Fe II] {\lambda}5.34{\mu}m and [Ar II] {\lambda}6.99{\mu}m lines are bright on the nucleus and in the starburst ring, as opposed to H2 S(5) {\lambda}6.91{\mu}m which is strongly peaked at the center and surrounding ISM. The high-ionization [Mg V] line is resolved and shows a broad, blueshifted component associated with the outflow. It has a nearly face-on geometry that is strongly peaked on the nucleus, where it reaches a maximum velocity of -650 km/s, and extends about 400 pc to the East. Regions of enhanced velocity dispersion in H2 and [Fe II] {\sim}180 pc from the AGN that also show high L(H2)/L(PAH) and L([Fe II])/L(Pf{\alpha}) ratios to the W and N of the nucleus pinpoint regions where the ionized outflow is depositing energy, via shocks, into the dense interstellar medium between the nucleus and the starburst ring. These resolved mid-infrared observations of the nuclear gas dynamics demonstrate the power of JWST and its high-sensitivity integral-field spectroscopic capability to resolve feedback processes around supermassive black holes in the dusty cores of nearby LIRGs.

astro-ph.GA↗

arXiv2022

GOALS-JWST: Hidden Star Formation and Extended PAH Emission in the Luminous Infrared Galaxy VV 114

James Webb Space Telescope (JWST) Mid-InfraRed Instrument (MIRI) images of the luminous infrared (IR) galaxy VV 114 are presented. This redshift ~ 0.020 merger has a western component (VV 114W) rich in optical star clusters and an eastern component (VV 114E) hosting a luminous mid-IR nucleus hidden at UV and optical wavelengths by dust lanes. With MIRI, the VV 114E nucleus resolves primarily into bright NE and SW cores separated by 630 pc. This nucleus comprises 45% of the 15um light of VV 114, with the NE and SW cores having IR luminosities, L_ IR (8-1000um) ~ 8+/-0.8x10^10 L_sun and ~ 5+/-0.5x10^10 L_sun, respectively, and IR densities, Sigma_IR >~ 2+/-0.2x10^13 L_sun / kpc^2 and >~ 7+/-0.7x10^12 L_sun / kpc^2, respectively -- in the range of Sigma_IR for the Orion star-forming core and the nuclei of Arp 220. The NE core, previously speculated to have an Active Galactic Nucleus (AGN), has starburst-like mid-IR colors. In contrast, the VV 114E SW has AGN-like colors. Approximately 40 star-forming knots with L_IR ~ 0.02-5x10^10 L_sun are identified, 25% of which have no optical counterpart. Finally, diffuse emission accounts for 40-60% of the mid-IR emission. Mostly notably, filamentary Poly-cyclic Aromatic Hydrocarbon (PAH) emission stochastically excited by UV and optical photons accounts for half of the 7.7um light of VV 114. This study illustrates the ability of JWST to detect obscured compact activity and distributed PAH emission in the most extreme starburst galaxies in the local Universe.

astro-ph.GA↗

arXiv2022

GOALS-JWST: Unveiling Dusty Compact Sources in the Merging Galaxy IIZw096

We have used the Mid-InfraRed Instrument (MIRI) on the James Webb Space Telescope (JWST) to obtain the first spatially resolved, mid-infrared (mid-IR) images of IIZw096, a merging luminous infrared galaxy (LIRG) at $z = 0.036$. Previous observations with the Spitzer Space Telescope suggested that the vast majority of the total IR luminosity (LIR) of the system originated from a small region outside of the two merging nuclei. New observations with JWST/MIRI now allow an accurate measurement of the location and luminosity density of the source that is responsible for the bulk of the IR emission. We estimate that 40-70% of the IR bolometric luminosity, or $3-5 \times 10^{11}\,{\rm{L_{\odot}}}$, arises from a source no larger than 175pc in radius, suggesting a luminosity density of at least $3-5 \times 10^{12} \, {\rm{L_{\odot} \, kpc^{-2}}}$. In addition, we detect 11 other star forming sources, five of which were previously unknown. The MIRI F1500W/F560W colors of most of these sources, including the source responsible for the bulk of the far-IR emission, are much redder than the nuclei of local LIRGs. These observations reveal the power of JWST to disentangle the complex regions at the hearts of merging, dusty galaxies.

astro-ph.GA↗