arXiv subjects

Thomas Maeke

Publications and source records attributed to Thomas Maeke.

4 recordsLinked to original sources

arXiv2024

Autonomous programmable microscopic electronic lablets optimized with digital control

Lablets are autonomous microscopic particles with programmable CMOS electronics that can control electrokinetic phenomena and electrochemical reactions in solution via actuator and sensor microelectrodes. In this paper, we describe the design and fabrication of optimized singulated lablets (CMOS3) with dimensions 140x140x50 micrometers carrying an integrated coplanar encapsulated supercapacitor as a rechargeable power supply. The lablets are designed to allow docking to one another or to a smart surface for interchange of energy, electronic information, and chemicals. The paper focusses on the digital and analog design of the lablets to allow significant programmable functionality in a microscopic footprint, including the control of autonomous actuation and sensing up to the level of being able to support a complete lablet self-reproduction life cycle, although experimentally this remains to be proven. The potential of lablets in autonomous sensing and control and for evolutionary experimentation are discussed.

cs.RO↗

arXiv2024

Design and fabrication of autonomous electronic lablets for chemical control

Lablets are autonomous microscopic particles with programmable CMOS electronics that canvcontrol electrokinetic phenomena and electrochemical reactions in solution via actuator and sensor microelectrodes. The lablets are designed to be rechargeable using an integrated supercapacitor, and to allow docking to one another or to a smart surface for interchange of energy, electronic information and chemicals. In this paper, we describe the design and fabrication of singulated lablets (CMOS2) at the scale of 100 by 200 μm, with the supercap adjacent to the functional lablet and occupying half the space. In other works, we have characterized the supercap and described the electronic design and proven functionality using arrays of these lablets. Here we present fabrication details for integrating functional coatings and the supercap and demonstrate electronic functionality of the lablets following singulation.

cs.RO↗

arXiv2007

Evolving inductive generalization via genetic self-assembly

We propose that genetic encoding of self-assembling components greatly enhances the evolution of complex systems and provides an efficient platform for inductive generalization, i.e. the inductive derivation of a solution to a problem with a potentially infinite number of instances from a limited set of test examples. We exemplify this in simulations by evolving scalable circuitry for several problems. One of them, digital multiplication, has been intensively studied in recent years, where hitherto the evolutionary design of only specific small multipliers was achieved. The fact that this and other problems can be solved in full generality employing self-assembly sheds light on the evolutionary role of self-assembly in biology and is of relevance for the design of complex systems in nano- and bionanotechnology.

q-bio.PE↗

arXiv2007

Multipolar Reactive DPD: A Novel Tool for Spatially Resolved Systems Biology

This article reports about a novel extension of dissipative particle dynamics (DPD) that allows the study of the collective dynamics of complex chemical and structural systems in a spatially resolved manner with a combinatorially complex variety of different system constituents. We show that introducing multipolar interactions between particles leads to extended membrane structures emerging in a self-organized manner and exhibiting both the necessary mechanical stability for transport and fluidity so as to provide a two-dimensional self-organizing dynamic reaction environment for kinetic studies in the context of cell biology. We further show that the emergent dynamics of extended membrane bound objects is in accordance with scaling laws imposed by physics.

q-bio.SC↗