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Thomas Moreau

Publications and source records attributed to Thomas Moreau.

At least 19 recordsLinked to original sources

ReMAP: Self-supervised learning to unveil brain representations and vulnerability

General anesthesia offers a rare opportunity to observe the human brain under a standardized, controlled perturbation. Yet intraoperative electroencephalography (EEG) is almost always reduced to a single proprietary depth index, collapsing a rich trajectory into one number and discarding how a brain moves between states. Here we ask whether the geometry of that trajectory, not merely the depth it reaches, carries clinically meaningful information. Using similarity-based self-supervised learning on raw, two-electrode frontal EEG, with no labels, we place each recording within a low-dimensional space in which anesthetic depth becomes one readable axis while the shape of a patient's path encodes additional structure. We validate the representation across two cohorts and two acquisition systems totaling more than 1,000 patients. Depth of anesthesia is predicted accurately (BIS mean absolute error = 3.2, R2 = 0.82), and in the sparse-montage setting our compact ( 68k parameter) model remains competitive with EEG foundation models orders of magnitude larger (4M-157M parameters), indicating that matching the representation to the recording dominates raw scale. The learned space organizes age along its own gradient, independent from depth, without supervision. The same space also aligns with interpretable anesthetic signatures like frontal alpha, slow-delta, and burst suppression, linking this data-driven representation to established neurophysiology. On an independent cohort with longitudinal follow-up, the geometry of the early trajectory separates 30- month cognitive and mortality outcomes complementary to age (AUROC 0.86). These results suggest that the path a brain traces through anesthesia is a label-efficient correlate of latent vulnerability, motivating prospective validation.

cs.LG

Accurate Decoding of Natural Sentences from Non-Invasive Brain Recordings

Restoring communication for people who have lost the ability to speak or move after a brain injury is a major challenge. While intracranial implants now enable high-performing brain-computer-interfaces, non-invasive alternatives are still lagging behind. Here, we present Brain2Qwerty v2, a model that can decode the production of natural sentences solely from real-time magnetoencephalography (MEG) recordings. By collecting 22,000 sentences typed by nine subjects, each recorded for 10 hours, our model leverages character, word and sentence-level representations to achieve an average word error rate (WER) of 39%. For our best participant, the model accurately decodes half of the sentences with one word error or less. Critically, decoding accuracy log-linearly improves with data volume, suggesting that the performance gap with intracranial approaches could be partially bridged through data scaling. We show that AI enables this performance in three main ways: the substitution of hand-crafted pipelines for event detection with deep learning, the finetuning of large language models to extract semantic representations, and the deployment of AI agents to iteratively refine our decoding pipeline via automated code development. Together, these results show that non-invasive brain-to-text decoding starts to operate at a level of accuracy previously thought exclusive to surgical implants, opening a path toward safe and efficient brain-computer-interfaces.

cs.CL

Crossing the Validation Crisis: Cross-Validation Reduces Benchmarking Variance Surprisingly Well

Modern machine learning progresses through empirical work, benchmarking new methods to evaluate relative performance. However, the statistical variability inherent to evaluation - exacerbated by the stochastic nature of many algorithms - often makes performance estimation unreliable due to the limited test samples available, leading to a validation crisis in which genuine advances are difficult to discern. In this work, we show that cross-validation improves markedly confidence when evaluating and comparing learning algorithm performances. We introduce the concept of sample gain, which quantifies the virtual data augmentation achieved by using multiple cross-validation splits to reduce benchmarking variance. Experiments on both synthetic and real-world datasets (histopathologic scans and NLP fine-tuning) demonstrate that multiple splits can substantially improve the reliability and stability of performance estimates, with diminishing returns often setting in later than expected. We also introduce a procedure to dynamically early-stop cross-validation by estimating from the first few folds if subsequent folds will bring large sample gains. Our findings highlight the value of pushing cross-validation on available samples to achieve robust and reliable benchmarking.

cs.LG

DANCE: Detect and Classify Events in EEG

Event identification in continuous neural recordings is a critical task in neuroscience. Decoding in EEG is dominated by classifying windows aligned to known event onsets. However, while available in controlled experiments, such onsets are absent in continuous real-world monitoring. Here, we introduce DANCE, a deep learning pipeline that frames neural decoding as a set-prediction problem and jointly detects and classifies events directly from raw, unaligned signals. Evaluated separately on ten datasets curated from the literature with a wide variety of event types (ranging from milliseconds to minutes in duration), our model outperforms existing methods on a broad range of cognitive, clinical and BCI tasks. This single architecture establishes a new state of the art in the competitive task of seizure monitoring and matches the accuracy of onset-informed models for BCI tasks. Overall, our method marks a step towards end-to-end asynchronous neural decoding models

cs.LG

Geometry-Aware Discretization Error of Diffusion Models

Practical diffusion sampling is a numerical approximation problem: under a fixed inference budget, one must simulate a reverse-time ODE or SDE using only a limited number of denoising steps, so discretization error is often the dominant source of error. Existing non-asymptotic analyses provide convergence guarantees, but are typically too loose and too insensitive to diffusion parameters to guide practical design: broad families of schedules receive the same rates, which depend on coarse worst-case quantities such as the dimension or the drift Lipschitz constant. We take a less ambitious but more informative route. In the exact-score setting, we derive first-order asymptotic expansions of the Euler-Maruyama weak and Fr\'echet discretization errors. These formulas hold for general smooth reverse diffusions and become fully explicit under Gaussian data. They show how discretization error adapts to the geometry of the data through the covariance spectrum, and how this geometry interacts with key diffusion parameters, including the diffusion schedules and the diffusion-term coefficient. This yields tractable objectives for geometry-aware parameter optimization. Finally, we show that the qualitative predictions of the Gaussian formulas remain robust across diffusion sampling problems with different geometries, including image generation on different datasets and image posterior sampling.

cs.LG

RoseCDL: Robust and Scalable Convolutional Dictionary Learning for Rare event and Anomaly Detection

Detecting rare events and anomalies in large-scale signals is essential in fields such as astronomy, physical simulations, and biomedical science. In many cases, this problem naturally decomposes into identifying common local patterns and detecting deviations that correspond to anomalies. Convolutional Dictionary Learning (CDL) is a powerful tool for modeling local structures, but its adoption for this task has been limited by computational demands and sensitivity to outliers. We introduce RoseCDL, a novel CDL algorithm designed for robust and scalable modeling of signal pattern distribution. RoseCDL leverages stochastic windowing for efficient training and incorporates inline outlier detection to enhance robustness. This enables unsupervised identification of anomalous and rare patterns in long signals based on the local reconstruction loss. Experiments on real-world datasets show that RoseCDL delivers improved detection accuracy and computational efficiency, making CDL practical for challenging detection tasks in large-scale signal analysis.

cs.LG

Simulation-Based Inference: A Practical Guide

A central challenge in many areas of science and engineering is to identify model parameters that are consistent with prior knowledge and empirical data. Bayesian inference offers a principled framework for this task, but can be computationally prohibitive when models are defined by stochastic simulators. Simulation-based Inference (SBI) is a suite of methods developed to overcome this limitation, which has enabled scientific discoveries in fields such as particle physics, astrophysics, and neuroscience. The core idea of SBI is to train neural networks on data generated by a simulator, without requiring access to likelihood evaluations. Once trained, inference is amortized: The neural network can rapidly perform Bayesian inference on empirical observations without requiring additional training or simulations. In this tutorial, we provide a practical guide for practitioners aiming to apply SBI methods. We outline a structured SBI workflow and offer practical guidelines and diagnostic tools for every stage of the process -- from setting up the simulator and prior, choosing and training inference networks, to performing inference and validating the results. We illustrate these steps through examples from astrophysics, psychophysics, and neuroscience. This tutorial empowers researchers to apply state-of-the-art SBI methods, facilitating efficient parameter inference for scientific discovery.

stat.ML

DeepInverse: A Python package for solving imaging inverse problems with deep learning

DeepInverse is an open-source PyTorch-based library for solving imaging inverse problems. The library covers all crucial steps in image reconstruction from the efficient implementation of forward operators (e.g., optics, MRI, tomography), to the definition and resolution of variational problems and the design and training of advanced neural network architectures. In this paper, we describe the main functionality of the library and discuss the main design choices.

eess.IV

From Score Matching to Diffusion: A Fine-Grained Error Analysis in the Gaussian Setting

Sampling from an unknown distribution, accessible only through discrete samples, is a fundamental problem at the core of generative AI. The current state-of-the-art methods follow a two-step process: first, estimating the score function (the gradient of a smoothed log-distribution) and then applying a diffusion-based sampling algorithm -- such as Langevin or Diffusion models. The resulting distribution's correctness can be impacted by four major factors: the generalization and optimization errors in score matching, and the discretization and minimal noise amplitude in the diffusion. In this paper, we make the sampling error explicit when using a diffusion sampler in the Gaussian setting. We provide a sharp analysis of the Wasserstein sampling error that arises from these four error sources. This allows us to rigorously track how the anisotropy of the data distribution (encoded by its power spectrum) interacts with key parameters of the end-to-end sampling method, including the number of initial samples, the stepsizes in both score matching and diffusion, and the noise amplitude. Notably, we show that the Wasserstein sampling error can be expressed as a kernel-type norm of the data power spectrum, where the specific kernel depends on the method parameters. This result provides a foundation for further analysis of the tradeoffs involved in optimizing sampling accuracy.

cs.LG

FiRe: Fixed-points of Restoration Priors for Solving Inverse Problems

Selecting an appropriate prior to compensate for information loss due to the measurement operator is a fundamental challenge in imaging inverse problems. Implicit priors based on denoising neural networks have become central to widely-used frameworks such as Plug-and-Play (PnP) algorithms. In this work, we introduce Fixed-points of Restoration (FiRe) priors as a new framework for expanding the notion of priors in PnP to general restoration models beyond traditional denoising models. The key insight behind FiRe is that smooth images emerge as fixed points of the composition of a degradation operator with the corresponding restoration model. This enables us to derive an explicit formula for our implicit prior by quantifying invariance of images under this composite operation. Adopting this fixed-point perspective, we show how various restoration networks can effectively serve as priors for solving inverse problems. The FiRe framework further enables ensemble-like combinations of multiple restoration models as well as acquisition-informed restoration networks, all within a unified optimization approach. Experimental results validate the effectiveness of FiRe across various inverse problems, establishing a new paradigm for incorporating pretrained restoration models into PnP-like algorithms. Code available at https://github.com/matthieutrs/fire.

eess.IV

sbi reloaded: a toolkit for simulation-based inference workflows

Scientists and engineers use simulators to model empirically observed phenomena. However, tuning the parameters of a simulator to ensure its outputs match observed data presents a significant challenge. Simulation-based inference (SBI) addresses this by enabling Bayesian inference for simulators, identifying parameters that match observed data and align with prior knowledge. Unlike traditional Bayesian inference, SBI only needs access to simulations from the model and does not require evaluations of the likelihood function. In addition, SBI algorithms do not require gradients through the simulator, allow for massive parallelization of simulations, and can perform inference for different observations without further simulations or training, thereby amortizing inference. Over the past years, we have developed, maintained, and extended sbi, a PyTorch-based package that implements Bayesian SBI algorithms based on neural networks. The sbi toolkit implements a wide range of inference methods, neural network architectures, sampling methods, and diagnostic tools. In addition, it provides well-tested default settings, but also offers flexibility to fully customize every step of the simulation-based inference workflow. Taken together, the sbi toolkit enables scientists and engineers to apply state-of-the-art SBI methods to black-box simulators, opening up new possibilities for aligning simulations with empirically observed data.

cs.LG

Analysis and Synthesis Denoisers for Forward-Backward Plug-and-Play Algorithms

In this work we study the behavior of the forward-backward (FB) algorithm when the proximity operator is replaced by a sub-iterative procedure to approximate a Gaussian denoiser, in a Plug-and-Play (PnP) fashion. In particular, we consider both analysis and synthesis Gaussian denoisers within a dictionary framework, obtained by unrolling dual-FB iterations or FB iterations, respectively. We analyze the associated minimization problems as well as the asymptotic behavior of the resulting FB-PnP iterations. In particular, we show that the synthesis Gaussian denoising problem can be viewed as a proximity operator. For each case, analysis and synthesis, we show that the FB-PnP algorithms solve the same problem whether we use only one or an infinite number of sub-iteration to solve the denoising problem at each iteration. To this aim, we show that each "one sub-iteration" strategy within the FB-PnP can be interpreted as a primal-dual algorithm when a warm-restart strategy is used. We further present similar results when using a Moreau-Yosida smoothing of the global problem, for an arbitrary number of sub-iterations. Finally, we provide numerical simulations to illustrate our theoretical results. In particular we first consider a toy compressive sensing example, as well as an image restoration problem in a deep dictionary framework.

math.OC

SKADA-Bench: Benchmarking Unsupervised Domain Adaptation Methods with Realistic Validation On Diverse Modalities

Unsupervised Domain Adaptation (DA) consists of adapting a model trained on a labeled source domain to perform well on an unlabeled target domain with some data distribution shift. While many methods have been proposed in the literature, fair and realistic evaluation remains an open question, particularly due to methodological difficulties in selecting hyperparameters in the unsupervised setting. With SKADA-bench, we propose a framework to evaluate DA methods on diverse modalities, beyond computer vision task that have been largely explored in the literature. We present a complete and fair evaluation of existing shallow algorithms, including reweighting, mapping, and subspace alignment. Realistic hyperparameter selection is performed with nested cross-validation and various unsupervised model selection scores, on both simulated datasets with controlled shifts and real-world datasets across diverse modalities, such as images, text, biomedical, and tabular data. Our benchmark highlights the importance of realistic validation and provides practical guidance for real-life applications, with key insights into the choice and impact of model selection approaches. SKADA-bench is open-source, reproducible, and can be easily extended with novel DA methods, datasets, and model selection criteria without requiring re-evaluating competitors. SKADA-bench is available on Github at https://github.com/scikit-adaptation/skada-bench.

cs.LG

Unmixing Noise from Hawkes Process to Model Learned Physiological Events

Physiological signal analysis often involves identifying events crucial to understanding biological dynamics. Traditional methods rely on handcrafted procedures or supervised learning, presenting challenges such as expert dependence, lack of robustness, and the need for extensive labeled data. Data-driven methods like Convolutional Dictionary Learning (CDL) offer an alternative but tend to produce spurious detections. This work introduces UNHaP (Unmix Noise from Hawkes Processes), a novel approach addressing the joint learning of temporal structures in events and the removal of spurious detections. Leveraging marked Hawkes processes, UNHaP distinguishes between events of interest and spurious ones. By treating the event detection output as a mixture of structured and unstructured events, UNHaP efficiently unmixes these processes and estimates their parameters. This approach significantly enhances the understanding of event distributions while minimizing false detection rates.

eess.SP

Flexible Parametric Inference for Space-Time Hawkes Processes

Many modern spatio-temporal data sets, in sociology, epidemiology or seismology, for example, exhibit self-exciting characteristics, triggering and clustering behaviors both at the same time, that a suitable Hawkes space-time process can accurately capture. This paper aims to develop a fast and flexible parametric inference technique to recover the parameters of the kernel functions involved in the intensity function of a space-time Hawkes process based on such data. Our statistical approach combines three key ingredients: 1) kernels with finite support are considered, 2) the space-time domain is appropriately discretized, and 3) (approximate) precomputations are used. The inference technique we propose then consists of a $\ell_2$ gradient-based solver that is fast and statistically accurate. In addition to describing the algorithmic aspects, numerical experiments have been carried out on synthetic and real spatio-temporal data, providing solid empirical evidence of the relevance of the proposed methodology.

stat.ML

The largest EEG-based BCI reproducibility study for open science: the MOABB benchmark

Objective. This study conduct an extensive Brain-computer interfaces (BCI) reproducibility analysis on open electroencephalography datasets, aiming to assess existing solutions and establish open and reproducible benchmarks for effective comparison within the field. The need for such benchmark lies in the rapid industrial progress that has given rise to undisclosed proprietary solutions. Furthermore, the scientific literature is dense, often featuring challenging-to-reproduce evaluations, making comparisons between existing approaches arduous. Approach. Within an open framework, 30 machine learning pipelines (separated into raw signal: 11, Riemannian: 13, deep learning: 6) are meticulously re-implemented and evaluated across 36 publicly available datasets, including motor imagery (14), P300 (15), and SSVEP (7). The analysis incorporates statistical meta-analysis techniques for results assessment, encompassing execution time and environmental impact considerations. Main results. The study yields principled and robust results applicable to various BCI paradigms, emphasizing motor imagery, P300, and SSVEP. Notably, Riemannian approaches utilizing spatial covariance matrices exhibit superior performance, underscoring the necessity for significant data volumes to achieve competitive outcomes with deep learning techniques. The comprehensive results are openly accessible, paving the way for future research to further enhance reproducibility in the BCI domain. Significance. The significance of this study lies in its contribution to establishing a rigorous and transparent benchmark for BCI research, offering insights into optimal methodologies and highlighting the importance of reproducibility in driving advancements within the field.

eess.SP

Coupling elastic media to gravitational waves: an effective field theory approach

The interaction of a gravitational wave (GW) with an elastic body is usually described in terms of a GW "force" driving the oscillations of the body's normal modes. However, this description is only possible for GW frequencies for which the response of the elastic body is dominated by a few normal modes. At higher frequencies the normal modes blend into a quasi-continuum and a field-theoretical description, as pioneered by Dyson already in 1969, becomes necessary. However, since the metric perturbation $h_{\mu\nu}$ is an intrinsically relativistic object, a consistent coupling to GWs can only be obtained within a relativistic (and, in fact generally covariant) theory of elasticity. We develop such a formalism using the methods of modern effective field theories, and we use it to provide a derivation of the interaction of elastic bodies with GWs valid also in the high-frequency regime, providing a first-principle derivation of Dyson's result (and partially correcting it). We also stress that the field-theoretical results are obtained working in the TT frame, while the description in terms of a force driving the normal modes is only valid in the proper detector frame. We show how to transform the results between the two frames. Beside an intrinsic conceptual interest, these results are relevant to the computation of the sensitivity of the recently proposed Lunar Gravitational Wave Antenna.

gr-qc

S-JEPA: towards seamless cross-dataset transfer through dynamic spatial attention

Motivated by the challenge of seamless cross-dataset transfer in EEG signal processing, this article presents an exploratory study on the use of Joint Embedding Predictive Architectures (JEPAs). In recent years, self-supervised learning has emerged as a promising approach for transfer learning in various domains. However, its application to EEG signals remains largely unexplored. In this article, we introduce Signal-JEPA for representing EEG recordings which includes a novel domain-specific spatial block masking strategy and three novel architectures for downstream classification. The study is conducted on a 54 subjects dataset and the downstream performance of the models is evaluated on three different BCI paradigms: motor imagery, ERP and SSVEP. Our study provides preliminary evidence for the potential of JEPAs in EEG signal encoding. Notably, our results highlight the importance of spatial filtering for accurate downstream classification and reveal an influence of the length of the pre-training examples but not of the mask size on the downstream performance.

cs.LG