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Thomas Pock

Publications and source records attributed to Thomas Pock.

At least 37 records · Page 2Linked to original sources

Bilevel learning of regularization models and their discretization for image deblurring and super-resolution

Bilevel learning is a powerful optimization technique that has extensively been employed in recent years to bridge the world of model-driven variational approaches with data-driven methods. Upon suitable parametrization of the desired quantities of interest (e.g., regularization terms or discretization filters), such approach computes optimal parameter values by solving a nested optimization problem where the variational model acts as a constraint. In this work, we consider two different use cases of bilevel learning for the problem of image restoration. First, we focus on learning scalar weights and convolutional filters defining a Field of Experts regularizer to restore natural images degraded by blur and noise. For improving the practical performance, the lower-level problem is solved by means of a gradient descent scheme combined with a line-search strategy based on the Barzilai-Borwein rule. As a second application, the bilevel setup is employed for learning a discretization of the popular total variation regularizer for solving image restoration problems (in particular, deblurring and super-resolution). Numerical results show the effectiveness of the approach and their generalization to multiple tasks.

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Score-Based Generative Models for Medical Image Segmentation using Signed Distance Functions

Medical image segmentation is a crucial task that relies on the ability to accurately identify and isolate regions of interest in medical images. Thereby, generative approaches allow to capture the statistical properties of segmentation masks that are dependent on the respective structures. In this work we propose a conditional score-based generative modeling framework to represent the signed distance function (SDF) leading to an implicit distribution of segmentation masks. The advantage of leveraging the SDF is a more natural distortion when compared to that of binary masks. By learning the score function of the conditional distribution of SDFs we can accurately sample from the distribution of segmentation masks, allowing for the evaluation of statistical quantities. Thus, this probabilistic representation allows for the generation of uncertainty maps represented by the variance, which can aid in further analysis and enhance the predictive robustness. We qualitatively and quantitatively illustrate competitive performance of the proposed method on a public nuclei and gland segmentation data set, highlighting its potential utility in medical image segmentation applications.

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On the Relationship Between RNN Hidden State Vectors and Semantic Ground Truth

We examine the assumption that the hidden-state vectors of recurrent neural networks (RNNs) tend to form clusters of semantically similar vectors, which we dub the clustering hypothesis. While this hypothesis has been assumed in the analysis of RNNs in recent years, its validity has not been studied thoroughly on modern neural network architectures. We examine the clustering hypothesis in the context of RNNs that were trained to recognize regular languages. This enables us to draw on perfect ground-truth automata in our evaluation, against which we can compare the RNN's accuracy and the distribution of the hidden-state vectors. We start with examining the (piecewise linear) separability of an RNN's hidden-state vectors into semantically different classes. We continue the analysis by computing clusters over the hidden-state vector space with multiple state-of-the-art unsupervised clustering approaches. We formally analyze the accuracy of computed clustering functions and the validity of the clustering hypothesis by determining whether clusters group semantically similar vectors to the same state in the ground-truth model. Our evaluation supports the validity of the clustering hypothesis in the majority of examined cases. We observed that the hidden-state vectors of well-trained RNNs are separable, and that the unsupervised clustering techniques succeed in finding clusters of similar state vectors.

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Stable Deep MRI Reconstruction using Generative Priors

Data-driven approaches recently achieved remarkable success in magnetic resonance imaging (MRI) reconstruction, but integration into clinical routine remains challenging due to a lack of generalizability and interpretability. In this paper, we address these challenges in a unified framework based on generative image priors. We propose a novel deep neural network based regularizer which is trained in a generative setting on reference magnitude images only. After training, the regularizer encodes higher-level domain statistics which we demonstrate by synthesizing images without data. Embedding the trained model in a classical variational approach yields high-quality reconstructions irrespective of the sub-sampling pattern. In addition, the model shows stable behavior when confronted with out-of-distribution data in the form of contrast variation. Furthermore, a probabilistic interpretation provides a distribution of reconstructions and hence allows uncertainty quantification. To reconstruct parallel MRI, we propose a fast algorithm to jointly estimate the image and the sensitivity maps. The results demonstrate competitive performance, on par with state-of-the-art end-to-end deep learning methods, while preserving the flexibility with respect to sub-sampling patterns and allowing for uncertainty quantification.

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Learned Discretization Schemes for the Second-Order Total Generalized Variation

The total generalized variation extends the total variation by incorporating higher-order smoothness. Thus, it can also suffer from similar discretization issues related to isotropy. Inspired by the success of novel discretization schemes of the total variation, there has been recent work to improve the second-order total generalized variation discretization, based on the same design idea. In this work, we propose to extend this to a general discretization scheme based on interpolation filters, for which we prove variational consistency. We then describe how to learn these interpolation filters to optimize the discretization for various imaging applications. We illustrate the performance of the method on a synthetic data set as well as for natural image denoising.

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Learning Gradually Non-convex Image Priors Using Score Matching

In this paper, we propose a unified framework of denoising score-based models in the context of graduated non-convex energy minimization. We show that for sufficiently large noise variance, the associated negative log density -- the energy -- becomes convex. Consequently, denoising score-based models essentially follow a graduated non-convexity heuristic. We apply this framework to learning generalized Fields of Experts image priors that approximate the joint density of noisy images and their associated variances. These priors can be easily incorporated into existing optimization algorithms for solving inverse problems and naturally implement a fast and robust graduated non-convexity mechanism.

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Explicit Diffusion of Gaussian Mixture Model Based Image Priors

In this work we tackle the problem of estimating the density $f_X$ of a random variable $X$ by successive smoothing, such that the smoothed random variable $Y$ fulfills $(\partial_t - Δ_1)f_Y(\,\cdot\,, t) = 0$, $f_Y(\,\cdot\,, 0) = f_X$. With a focus on image processing, we propose a product/fields of experts model with Gaussian mixture experts that admits an analytic expression for $f_Y (\,\cdot\,, t)$ under an orthogonality constraint on the filters. This construction naturally allows the model to be trained simultaneously over the entire diffusion horizon using empirical Bayes. We show preliminary results on image denoising where our model leads to competitive results while being tractable, interpretable, and having only a small number of learnable parameters. As a byproduct, our model can be used for reliable noise estimation, allowing blind denoising of images corrupted by heteroscedastic noise.

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Quantum Transport in Open Spin Chains using Neural-Network Quantum States

In this work we study the treatment of asymmetric open quantum systems with neural networks based on the restricted Boltzmann machine. In particular, we are interested in the non-equilibrium steady state current in the boundary-driven (anisotropic) Heisenberg spin chain. We address previously published difficulties in treating asymmetric dissipative systems with neural-network quantum states and Monte-Carlo sampling and present an optimization method and a sampling technique that can be used to obtain high-fidelity steady state approximations of such systems. We point out some inherent symmetries of the Lindblad operator under consideration and exploit them during sampling. We show that local observables are not always a good indicator of the quality of the approximation and finally present results for the spin current that are in agreement with known results of simple open Heisenberg chains.

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Is Appearance Free Action Recognition Possible?

Intuition might suggest that motion and dynamic information are key to video-based action recognition. In contrast, there is evidence that state-of-the-art deep-learning video understanding architectures are biased toward static information available in single frames. Presently, a methodology and corresponding dataset to isolate the effects of dynamic information in video are missing. Their absence makes it difficult to understand how well contemporary architectures capitalize on dynamic vs. static information. We respond with a novel Appearance Free Dataset (AFD) for action recognition. AFD is devoid of static information relevant to action recognition in a single frame. Modeling of the dynamics is necessary for solving the task, as the action is only apparent through consideration of the temporal dimension. We evaluated 11 contemporary action recognition architectures on AFD as well as its related RGB video. Our results show a notable decrease in performance for all architectures on AFD compared to RGB. We also conducted a complimentary study with humans that shows their recognition accuracy on AFD and RGB is very similar and much better than the evaluated architectures on AFD. Our results motivate a novel architecture that revives explicit recovery of optical flow, within a contemporary design for best performance on AFD and RGB.

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Computed Tomography Reconstruction using Generative Energy-Based Priors

In the past decades, Computed Tomography (CT) has established itself as one of the most important imaging techniques in medicine. Today, the applicability of CT is only limited by the deposited radiation dose, reduction of which manifests in noisy or incomplete measurements. Thus, the need for robust reconstruction algorithms arises. In this work, we learn a parametric regularizer with a global receptive field by maximizing it's likelihood on reference CT data. Due to this unsupervised learning strategy, our trained regularizer truly represents higher-level domain statistics, which we empirically demonstrate by synthesizing CT images. Moreover, this regularizer can easily be applied to different CT reconstruction problems by embedding it in a variational framework, which increases flexibility and interpretability compared to feed-forward learning-based approaches. In addition, the accompanying probabilistic perspective enables experts to explore the full posterior distribution and may quantify uncertainty of the reconstruction approach. We apply the regularizer to limited-angle and few-view CT reconstruction problems, where it outperforms traditional reconstruction algorithms by a large margin.

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Bayesian Uncertainty Estimation of Learned Variational MRI Reconstruction

Recent deep learning approaches focus on improving quantitative scores of dedicated benchmarks, and therefore only reduce the observation-related (aleatoric) uncertainty. However, the model-immanent (epistemic) uncertainty is less frequently systematically analyzed. In this work, we introduce a Bayesian variational framework to quantify the epistemic uncertainty. To this end, we solve the linear inverse problem of undersampled MRI reconstruction in a variational setting. The associated energy functional is composed of a data fidelity term and the total deep variation (TDV) as a learned parametric regularizer. To estimate the epistemic uncertainty we draw the parameters of the TDV regularizer from a multivariate Gaussian distribution, whose mean and covariance matrix are learned in a stochastic optimal control problem. In several numerical experiments, we demonstrate that our approach yields competitive results for undersampled MRI reconstruction. Moreover, we can accurately quantify the pixelwise epistemic uncertainty, which can serve radiologists as an additional resource to visualize reconstruction reliability.

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GEASI: Geodesic-based Earliest Activation Sites Identification in cardiac models

The identification of the initial ventricular activation sequence is a critical step for the correct personalization of patient-specific cardiac models. In healthy conditions, the Purkinje network is the main source of the electrical activation, but under pathological conditions the so-called earliest activation sites (EASs) are possibly sparser and more localized. Yet, their number, location and timing may not be easily inferred from remote recordings, such as the epicardial activation or the 12-lead electrocardiogram (ECG), due to the underlying complexity of the model. In this work, we introduce GEASI (Geodesic-based Earliest Activation Sites Identification) as a novel approach to simultaneously identify all EASs. To this end, we start from the anisotropic eikonal equation modeling cardiac electrical activation and exploit its Hamilton--Jacobi formulation to minimize a given objective function, e.g. the quadratic mismatch to given activation measurements. This versatile approach can be extended to estimate the number of activation sites by means of the topological gradient, or fitting a given ECG. We conducted various experiments in 2D and 3D for in-silico models and an in-vivo intracardiac recording collected from a patient undergoing cardiac resynchronization therapy. The results demonstrate the clinical applicability of GEASI for potential future personalized models and clinical intervention.

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One-sided Frank-Wolfe algorithms for saddle problems

We study a class of convex-concave saddle-point problems of the form $\min_x\max_y \langle Kx,y\rangle+f_{\cal{P}}(x)-h^\ast(y)$ where $K$ is a linear operator, $f_{\cal{P}}$ is the sum of a convex function $f$ with a Lipschitz-continuous gradient and the indicator function of a bounded convex polytope $\cal{P}$, and $h^\ast$ is a convex (possibly nonsmooth) function. Such problem arises, for example, as a Lagrangian relaxation of various discrete optimization problems. Our main assumptions are the existence of an efficient linear minimization oracle ($lmo$) for $f_{\cal{P}}$ and an efficient proximal map for $h^*$ which motivate the solution via a blend of proximal primal-dual algorithms and Frank-Wolfe algorithms. In case $h^*$ is the indicator function of a linear constraint and function $f$ is quadratic, we show a $O(1/n^2)$ convergence rate on the dual objective, requiring $O(n \log n)$ calls of $lmo$. If the problem comes from the constrained optimization problem $\min_{x\in\mathbb R^d}\{f_{\cal{P}}(x)\:|\:Ax-b=0\}$ then we additionally get bound $O(1/n^2)$ both on the primal gap and on the infeasibility gap. In the most general case, we show a $O(1/n)$ convergence rate of the primal-dual gap again requiring $O(n\log n)$ calls of $lmo$. To the best of our knowledge, this improves on the known convergence rates for the considered class of saddle-point problems. We show applications to labeling problems frequently appearing in machine learning and computer vision.

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Learning atrial fiber orientations and conductivity tensors from intracardiac maps using physics-informed neural networks

Electroanatomical maps are a key tool in the diagnosis and treatment of atrial fibrillation. Current approaches focus on the activation times recorded. However, more information can be extracted from the available data. The fibers in cardiac tissue conduct the electrical wave faster, and their direction could be inferred from activation times. In this work, we employ a recently developed approach, called physics informed neural networks, to learn the fiber orientations from electroanatomical maps, taking into account the physics of the electrical wave propagation. In particular, we train the neural network to weakly satisfy the anisotropic eikonal equation and to predict the measured activation times. We use a local basis for the anisotropic conductivity tensor, which encodes the fiber orientation. The methodology is tested both in a synthetic example and for patient data. Our approach shows good agreement in both cases, with an RMSE of 2.2ms on the in-silico data and outperforming a state of the art method on the patient data. The results show a first step towards learning the fiber orientations from electroanatomical maps with physics-informed neural networks.

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Shared Prior Learning of Energy-Based Models for Image Reconstruction

We propose a novel learning-based framework for image reconstruction particularly designed for training without ground truth data, which has three major building blocks: energy-based learning, a patch-based Wasserstein loss functional, and shared prior learning. In energy-based learning, the parameters of an energy functional composed of a learned data fidelity term and a data-driven regularizer are computed in a mean-field optimal control problem. In the absence of ground truth data, we change the loss functional to a patch-based Wasserstein functional, in which local statistics of the output images are compared to uncorrupted reference patches. Finally, in shared prior learning, both aforementioned optimal control problems are optimized simultaneously with shared learned parameters of the regularizer to further enhance unsupervised image reconstruction. We derive several time discretization schemes of the gradient flow and verify their consistency in terms of Mosco convergence. In numerous numerical experiments, we demonstrate that the proposed method generates state-of-the-art results for various image reconstruction applications--even if no ground truth images are available for training.

cs.CV↗

PIEMAP: Personalized Inverse Eikonal Model from cardiac Electro-Anatomical Maps

Electroanatomical mapping, a keystone diagnostic tool in cardiac electrophysiology studies, can provide high-density maps of the local electric properties of the tissue. It is therefore tempting to use such data to better individualize current patient-specific models of the heart through a data assimilation procedure and to extract potentially insightful information such as conduction properties. Parameter identification for state-of-the-art cardiac models is however a challenging task. In this work, we introduce a novel inverse problem for inferring the anisotropic structure of the conductivity tensor, that is fiber orientation and conduction velocity along and across fibers, of an eikonal model for cardiac activation. The proposed method, named PIEMAP, performed robustly with synthetic data and showed promising results with clinical data. These results suggest that PIEMAP could be a useful supplement in future clinical workflows of personalized therapies.

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BP-MVSNet: Belief-Propagation-Layers for Multi-View-Stereo

In this work, we propose BP-MVSNet, a convolutional neural network (CNN)-based Multi-View-Stereo (MVS) method that uses a differentiable Conditional Random Field (CRF) layer for regularization. To this end, we propose to extend the BP layer and add what is necessary to successfully use it in the MVS setting. We therefore show how we can calculate a normalization based on the expected 3D error, which we can then use to normalize the label jumps in the CRF. This is required to make the BP layer invariant to different scales in the MVS setting. In order to also enable fractional label jumps, we propose a differentiable interpolation step, which we embed into the computation of the pairwise term. These extensions allow us to integrate the BP layer into a multi-scale MVS network, where we continuously improve a rough initial estimate until we get high quality depth maps as a result. We evaluate the proposed BP-MVSNet in an ablation study and conduct extensive experiments on the DTU, Tanks and Temples and ETH3D data sets. The experiments show that we can significantly outperform the baseline and achieve state-of-the-art results.

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Improving Optical Flow on a Pyramid Level

In this work we review the coarse-to-fine spatial feature pyramid concept, which is used in state-of-the-art optical flow estimation networks to make exploration of the pixel flow search space computationally tractable and efficient. Within an individual pyramid level, we improve the cost volume construction process by departing from a warping- to a sampling-based strategy, which avoids ghosting and hence enables us to better preserve fine flow details. We further amplify the positive effects through a level-specific, loss max-pooling strategy that adaptively shifts the focus of the learning process on under-performing predictions. Our second contribution revises the gradient flow across pyramid levels. The typical operations performed at each pyramid level can lead to noisy, or even contradicting gradients across levels. We show and discuss how properly blocking some of these gradient components leads to improved convergence and ultimately better performance. Finally, we introduce a distillation concept to counteract the issue of catastrophic forgetting and thus preserving knowledge over models sequentially trained on multiple datasets. Our findings are conceptually simple and easy to implement, yet result in compelling improvements on relevant error measures that we demonstrate via exhaustive ablations on datasets like Flying Chairs2, Flying Things, Sintel and KITTI. We establish new state-of-the-art results on the challenging Sintel and KITTI 2012 test datasets, and even show the portability of our findings to different optical flow and depth from stereo approaches.

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