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Tianfu Wang

Publications and source records attributed to Tianfu Wang.

58 records · Page 4Linked to original sources

High Tissue Contrast MRI Synthesis Using Multi-Stage Attention-GAN for Glioma Segmentation

Magnetic resonance imaging (MRI) provides varying tissue contrast images of internal organs based on a strong magnetic field. Despite the non-invasive advantage of MRI in frequent imaging, the low contrast MR images in the target area make tissue segmentation a challenging problem. This paper demonstrates the potential benefits of image-to-image translation techniques to generate synthetic high tissue contrast (HTC) images. Notably, we adopt a new cycle generative adversarial network (CycleGAN) with an attention mechanism to increase the contrast within underlying tissues. The attention block, as well as training on HTC images, guides our model to converge on certain tissues. To increase the resolution of HTC images, we employ multi-stage architecture to focus on one particular tissue as a foreground and filter out the irrelevant background in each stage. This multi-stage structure also alleviates the common artifacts of the synthetic images by decreasing the gap between source and target domains. We show the application of our method for synthesizing HTC images on brain MR scans, including glioma tumor. We also employ HTC MR images in both the end-to-end and two-stage segmentation structure to confirm the effectiveness of these images. The experiments over three competitive segmentation baselines on BraTS 2018 dataset indicate that incorporating the synthetic HTC images in the multi-modal segmentation framework improves the average Dice scores 0.8%, 0.6%, and 0.5% on the whole tumor, tumor core, and enhancing tumor, respectively, while eliminating one real MRI sequence from the segmentation procedure.

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Brain Tumor Synthetic Segmentation in 3D Multimodal MRI Scans

The magnetic resonance (MR) analysis of brain tumors is widely used for diagnosis and examination of tumor subregions. The overlapping area among the intensity distribution of healthy, enhancing, non-enhancing, and edema regions makes the automatic segmentation a challenging task. Here, we show that a convolutional neural network trained on high-contrast images can transform the intensity distribution of brain lesions in its internal subregions. Specifically, a generative adversarial network (GAN) is extended to synthesize high-contrast images. A comparison of these synthetic images and real images of brain tumor tissue in MR scans showed significant segmentation improvement and decreased the number of real channels for segmentation. The synthetic images are used as a substitute for real channels and can bypass real modalities in the multimodal brain tumor segmentation framework. Segmentation results on BraTS 2019 dataset demonstrate that our proposed approach can efficiently segment the tumor areas. In the end, we predict patient survival time based on volumetric features of the tumor subregions as well as the age of each case through several regression models.

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A deep network for sinogram and CT image reconstruction

A CT image can be well reconstructed when the sampling rate of the sinogram satisfies the Nyquist criteria and the sampled signal is noise-free. However, in practice, the sinogram is usually contaminated by noise, which degrades the quality of a reconstructed CT image. In this paper, we design a deep network for sinogram and CT image reconstruction. The network consists of two cascaded blocks that are linked by a filter backprojection (FBP) layer, where the former block is responsible for denoising and completing the sinograms while the latter is used to removing the noise and artifacts of the CT images. Experimental results show that the reconstructed CT images by our methods have the highest PSNR and SSIM in average compared to state of the art methods.

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SANet:Superpixel Attention Network for Skin Lesion Attributes Detection

The accurate detection of lesion attributes is meaningful for both the computeraid diagnosis system and dermatologists decisions. However, unlike lesion segmentation and melenoma classification, there are few deep learning methods and literatures focusing on this task. Currently, the lesion attribute detection still remains challenging due to the extremely unbalanced class distribution and insufficient samples, as well as large intraclass and low interclass variations. To solve these problems, we propose a deep learning framework named superpixel attention network (SANet). Firstly, we segment input images into small regions and shuffle the obtained regions by the random shuttle mechanism (RSM). Secondly, we apply the SANet to capture discriminative features and reconstruct input images. Specifically, SANet contains two sub modules: superpixel average pooling and superpixel at tention module. We introduce a superpixel average pooling to reformulate the superpixel classification problem as a superpixel segmentation problem and a SAMis utilized to focus on discriminative superpixel regions and feature channels. Finally, we design a novel but effective loss, namely global balancing loss to address the serious data imbalance in ISIC 2018 Task 2 lesion attributes detection dataset. The proposed method achieves quite good performance on the ISIC 2018 Task 2 challenge.

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