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Tianliang Yao

Publications and source records attributed to Tianliang Yao.

13 recordsLinked to original sources

Learning Expert Strategy for Autonomous Robotic Endovascular Intervention via Decoupled Procedural Execution

Endovascular interventions are high-stakes procedures requiring precise device operation within complex and tortuous vascular anatomies. Autonomous endovascular navigation has the potential to standardize procedural quality and reduce the performance variability inherent in manual operation. Although Reinforcement Learning (RL) approaches have demonstrated promise in enabling autonomy in endovascular intervention, they often struggle with explicit constraint satisfaction and safety guarantees. To address these challenges, a learning-based expert strategy is introduced, enhancing procedural consistency in autonomous endovascular intervention by explicitly decoupling high-level strategic decision-making from low-level procedural execution. The proposed framework replicates the expert clinical decision-making process: a strategic RL policy generates global navigation intents, which are subsequently refined through an expert-informed execution module. This module ensures that robot movements strictly adhere to expert operational norms, real-time kinematic limits, and vessel safety constraints. Experimental evaluation across high-fidelity 3D simulations and a real-world robotic platform demonstrates that the proposed framework not only outperforms baseline policies but also effectively replicates expert-level proficiency. The framework achieves a high navigation success rate (> 96%) and a 29.3% reduction in operational steps, which translates to enhanced operative efficiency and minimized device-vessel interaction. Furthermore, a 13% reduction in trajectory variance indicates superior procedural standardization, aligning autonomous behavior with established clinical norms. These results underscore its potential to enhance the predictability, safety, and consistency of robotic endovascular interventions.

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Vision-Language Procedural Reasoning for Context-Aware Reward Modeling of Robotic Endovascular Guidewire Navigation

Robotic-assisted endovascular interventions demand accurate, stable, and context-aware guidewire navigation in complex and patient-specific vascular anatomies. Despite recent advances in robotic precision and learning-based control, existing autonomous navigation methods remain limited by their reliance on static reward functions and the lack of explicit procedural reasoning regarding anatomical context and task progression. To address these challenges, this paper proposes a vision-language procedural reasoning (VL-PR) framework for autonomous guidewire navigation. The framework integrates a multimodal large language model (MLLM) as a procedural reasoning module that interprets real-time visual observations to infer high-level navigation contexts. Instead of generating low-level control commands, the inferred procedural insights enable context-aware reward adaptation by dynamically adjusting the importance of reward components across different navigation phases. This approach allows a single policy to resolve competing objectives and handle complex transitions while preserving a consistent global task goal. Experiments on a physical robotic platform across diverse vascular scenarios demonstrate enhanced task reliability and streamlined navigational efficiency, highlighting the advantages over static-reward methods and offering a scalable solution for complex and multi-task robotic endovascular procedures.

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Vision-Based Reasoning with Topology-Encoded Graphs for Anatomical Path Disambiguation in Robot-Assisted Endovascular Navigation

Robotic-assisted percutaneous coronary intervention (PCI) is constrained by the inherent limitations of 2D Digital Subtraction Angiography (DSA). Unlike physicians, who can directly manipulate guidewires and integrate tactile feedback with their prior anatomical knowledge, teleoperated robotic systems must rely solely on 2D projections. This mode of operation, simultaneously lacking spatial context and tactile sensation, may give rise to projection-induced ambiguities at vascular bifurcations. To address this challenge, we propose a two-stage framework (SCAR-UNet-GAT) for real-time robotic path planning. In the first stage, SCAR-UNet, a spatial-coordinate-attention-regularized U-Net, is employed for accurate coronary vessel segmentation. The integration of multi-level attention mechanisms enhances the delineation of thin, tortuous vessels and improves robustness against imaging noise. From the resulting binary masks, vessel centerlines and bifurcation points are extracted, and geometric descriptors (e.g., branch diameter, intersection angles) are fused with local DSA patches to construct node features. In the second stage, a Graph Attention Network (GAT) reasons over the vessel graph to identify anatomically consistent and clinically feasible trajectories, effectively distinguishing true bifurcations from projection-induced false crossings. On a clinical DSA dataset, SCAR-UNet achieved a Dice coefficient of 93.1%. For path disambiguation, the proposed GAT-based method attained a success rate of 95.0% and a target-arrival success rate of 90.0%, substantially outperforming conventional shortest-path planning (60.0% and 55.0%) and heuristic-based planning (75.0% and 70.0%). Validation on a robotic platform further confirmed the practical feasibility and robustness of the proposed framework.

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Sample-Efficient Learning with Online Expert Correction for Autonomous Catheter Steering in Endovascular Bifurcation Navigation

Robot-assisted endovascular intervention offers a safe and effective solution for remote catheter manipulation, reducing radiation exposure while enabling precise navigation. Reinforcement learning (RL) has recently emerged as a promising approach for autonomous catheter steering; however, conventional methods suffer from sparse reward design and reliance on static vascular models, limiting their sample efficiency and generalization to intraoperative variations. To overcome these challenges, this paper introduces a sample-efficient RL framework with online expert correction for autonomous catheter steering in endovascular bifurcation navigation. The proposed framework integrates three key components: (1) A segmentation-based pose estimation module for accurate real-time state feedback, (2) A fuzzy controller for bifurcation-aware orientation adjustment, and (3) A structured reward generator incorporating expert priors to guide policy learning. By leveraging online expert correction, the framework reduces exploration inefficiency and enhances policy robustness in complex vascular structures. Experimental validation on a robotic platform using a transparent vascular phantom demonstrates that the proposed approach achieves convergence in 123 training episodes -- a 25.9% reduction compared to the baseline Soft Actor-Critic (SAC) algorithm -- while reducing average positional error to 83.8% of the baseline. These results indicate that combining sample-efficient RL with online expert correction enables reliable and accurate catheter steering, particularly in anatomically challenging bifurcation scenarios critical for endovascular navigation.

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Advancing Embodied Intelligence in Robotic-Assisted Endovascular Procedures: A Systematic Review of AI Solutions

Endovascular procedures have revolutionized vascular disease treatment, yet their manual execution is challenged by the demands for high precision, operator fatigue, and radiation exposure. Robotic systems have emerged as transformative solutions to mitigate these inherent limitations. A pivotal moment has arrived, where a confluence of pressing clinical needs and breakthroughs in AI creates an opportunity for a paradigm shift toward Embodied Intelligence (EI), enabling robots to navigate complex vascular networks and adapt to dynamic physiological conditions. Data-driven approaches, leveraging advanced computer vision, medical image analysis, and machine learning, drive this evolution by enabling real-time vessel segmentation, device tracking, and anatomical landmark detection. Reinforcement learning and imitation learning further enhance navigation strategies and replicate expert techniques. This review systematically analyzes the integration of EI into endovascular robotics, identifying profound systemic challenges such as the heterogeneity in validation standards and the gap between human mimicry and machine-native capabilities. Based on this analysis, a conceptual roadmap is proposed that reframes the ultimate objective away from systems that supplant clinical decision-making. This vision of augmented intelligence, where the clinician's role evolves into that of a high-level supervisor, provides a principled foundation for the future of the field.

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Real-Time 3D Guidewire Reconstruction from Intraoperative DSA Images for Robot-Assisted Endovascular Interventions

Accurate three-dimensional (3D) reconstruction of guidewire shapes is crucial for precise navigation in robot-assisted endovascular interventions. Conventional 2D Digital Subtraction Angiography (DSA) is limited by the absence of depth information, leading to spatial ambiguities that hinder reliable guidewire shape sensing. This paper introduces a novel multimodal framework for real-time 3D guidewire reconstruction, combining preoperative 3D Computed Tomography Angiography (CTA) with intraoperative 2D DSA images. The method utilizes robust feature extraction to address noise and distortion in 2D DSA data, followed by deformable image registration to align the 2D projections with the 3D CTA model. Subsequently, the inverse projection algorithm reconstructs the 3D guidewire shape, providing real-time, accurate spatial information. This framework significantly enhances spatial awareness for robotic-assisted endovascular procedures, effectively bridging the gap between preoperative planning and intraoperative execution. The system demonstrates notable improvements in real-time processing speed, reconstruction accuracy, and computational efficiency. The proposed method achieves a projection error of 1.76$\pm$0.08 pixels and a length deviation of 2.93$\pm$0.15\%, with a frame rate of 39.3$\pm$1.5 frames per second (FPS). These advancements have the potential to optimize robotic performance and increase the precision of complex endovascular interventions, ultimately contributing to better clinical outcomes.

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Real-Time Guidewire Tip Tracking Using a Siamese Network for Image-Guided Endovascular Procedures

An ever-growing incorporation of AI solutions into clinical practices enhances the efficiency and effectiveness of healthcare services. This paper focuses on guidewire tip tracking tasks during image-guided therapy for cardiovascular diseases, aiding physicians in improving diagnostic and therapeutic quality. A novel tracking framework based on a Siamese network with dual attention mechanisms combines self- and cross-attention strategies for robust guidewire tip tracking. This design handles visual ambiguities, tissue deformations, and imaging artifacts through enhanced spatial-temporal feature learning. Validation occurred on 3 randomly selected clinical digital subtraction angiography (DSA) sequences from a dataset of 15 sequences, covering multiple interventional scenarios. The results indicate a mean localization error of 0.421 $\pm$ 0.138 mm, with a maximum error of 1.736 mm, and a mean Intersection over Union (IoU) of 0.782. The framework maintains an average processing speed of 57.2 frames per second, meeting the temporal demands of endovascular imaging. Further validations with robotic platforms for automating diagnostics and therapies in clinical routines yielded tracking errors of 0.708 $\pm$ 0.695 mm and 0.148 $\pm$ 0.057 mm in two distinct experimental scenarios.

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VLMInferSlow: Evaluating the Efficiency Robustness of Large Vision-Language Models as a Service

Vision-Language Models (VLMs) have demonstrated great potential in real-world applications. While existing research primarily focuses on improving their accuracy, the efficiency remains underexplored. Given the real-time demands of many applications and the high inference overhead of VLMs, efficiency robustness is a critical issue. However, previous studies evaluate efficiency robustness under unrealistic assumptions, requiring access to the model architecture and parameters -- an impractical scenario in ML-as-a-service settings, where VLMs are deployed via inference APIs. To address this gap, we propose VLMInferSlow, a novel approach for evaluating VLM efficiency robustness in a realistic black-box setting. VLMInferSlow incorporates fine-grained efficiency modeling tailored to VLM inference and leverages zero-order optimization to search for adversarial examples. Experimental results show that VLMInferSlow generates adversarial images with imperceptible perturbations, increasing the computational cost by up to 128.47%. We hope this research raises the community's awareness about the efficiency robustness of VLMs.

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A Novel Coronary Artery Registration Method Based on Super-pixel Particle Swarm Optimization

Percutaneous Coronary Intervention (PCI) is a minimally invasive procedure that improves coronary blood flow and treats coronary artery disease. Although PCI typically requires 2D X-ray angiography (XRA) to guide catheter placement at real-time, computed tomography angiography (CTA) may substantially improve PCI by providing precise information of 3D vascular anatomy and status. To leverage real-time XRA and detailed 3D CTA anatomy for PCI, accurate multimodal image registration of XRA and CTA is required, to guide the procedure and avoid complications. This is a challenging process as it requires registration of images from different geometrical modalities (2D -> 3D and vice versa), with variations in contrast and noise levels. In this paper, we propose a novel multimodal coronary artery image registration method based on a swarm optimization algorithm, which effectively addresses challenges such as large deformations, low contrast, and noise across these imaging modalities. Our algorithm consists of two main modules: 1) preprocessing of XRA and CTA images separately, and 2) a registration module based on feature extraction using the Steger and Superpixel Particle Swarm Optimization algorithms. Our technique was evaluated on a pilot dataset of 28 pairs of XRA and CTA images from 10 patients who underwent PCI. The algorithm was compared with four state-of-the-art (SOTA) methods in terms of registration accuracy, robustness, and efficiency. Our method outperformed the selected SOTA baselines in all aspects. Experimental results demonstrate the significant effectiveness of our algorithm, surpassing the previous benchmarks and proposes a novel clinical approach that can potentially have merit for improving patient outcomes in coronary artery disease.

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DPNet: Dynamic Pooling Network for Tiny Object Detection

In unmanned aerial systems, especially in complex environments, accurately detecting tiny objects is crucial. Resizing images is a common strategy to improve detection accuracy, particularly for small objects. However, simply enlarging images significantly increases computational costs and the number of negative samples, severely degrading detection performance and limiting its applicability. This paper proposes a Dynamic Pooling Network (DPNet) for tiny object detection to mitigate these issues. DPNet employs a flexible down-sampling strategy by introducing a factor (df) to relax the fixed downsampling process of the feature map to an adjustable one. Furthermore, we design a lightweight predictor to predict df for each input image, which is used to decrease the resolution of feature maps in the backbone. Thus, we achieve input-aware downsampling. We also design an Adaptive Normalization Module (ANM) to make a unified detector compatible with different dfs. A guidance loss supervises the predictor's training. DPNet dynamically allocates computing resources to trade off between detection accuracy and efficiency. Experiments on the TinyCOCO and TinyPerson datasets show that DPNet can save over 35% and 25% GFLOPs, respectively, while maintaining comparable detection performance. The code will be made publicly available.

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Ultrasound-Guided Robotic Blood Drawing and In Vivo Studies on Submillimetre Vessels of Rats

Billions of vascular access procedures are performed annually worldwide, serving as a crucial first step in various clinical diagnostic and therapeutic procedures. For pediatric or elderly individuals, whose vessels are small in size (typically 2 to 3 mm in diameter for adults and less than 1 mm in children), vascular access can be highly challenging. This study presents an image-guided robotic system aimed at enhancing the accuracy of difficult vascular access procedures. The system integrates a 6-DoF robotic arm with a 3-DoF end-effector, ensuring precise navigation and needle insertion. Multi-modal imaging and sensing technologies have been utilized to endow the medical robot with precision and safety, while ultrasound imaging guidance is specifically evaluated in this study. To evaluate in vivo vascular access in submillimeter vessels, we conducted ultrasound-guided robotic blood drawing on the tail veins (with a diameter of 0.7 plus or minus 0.2 mm) of 40 rats. The results demonstrate that the system achieved a first-attempt success rate of 95 percent. The high first-attempt success rate in intravenous vascular access, even with small blood vessels, demonstrates the system's effectiveness in performing these procedures. This capability reduces the risk of failed attempts, minimizes patient discomfort, and enhances clinical efficiency.

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Sim4EndoR: A Reinforcement Learning Centered Simulation Platform for Task Automation of Endovascular Robotics

Robotic-assisted percutaneous coronary intervention (PCI) holds considerable promise for elevating precision and safety in cardiovascular procedures. Nevertheless, current systems heavily depend on human operators, resulting in variability and the potential for human error. To tackle these challenges, Sim4EndoR, an innovative reinforcement learning (RL) based simulation environment, is first introduced to bolster task-level autonomy in PCI. This platform offers a comprehensive and risk-free environment for the development, evaluation, and refinement of potential autonomous systems, enhancing data collection efficiency and minimizing the need for costly hardware trials. A notable aspect of the groundbreaking Sim4EndoR is its reward function, which takes into account the anatomical constraints of the vascular environment, utilizing the geometric characteristics of vessels to steer the learning process. By seamlessly integrating advanced physical simulations with neural network-driven policy learning, Sim4EndoR fosters efficient sim-to-real translation, paving the way for safer, more consistent robotic interventions in clinical practice, ultimately improving patient outcomes.

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Deep Learning for Personalized Electrocardiogram Diagnosis: A Review

The electrocardiogram (ECG) remains a fundamental tool in cardiac diagnostics, yet its interpretation traditionally reliant on the expertise of cardiologists. The emergence of deep learning has heralded a revolutionary era in medical data analysis, particularly in the domain of ECG diagnostics. However, inter-patient variability prohibit the generalibility of ECG-AI model trained on a population dataset, hence degrade the performance of ECG-AI on specific patient or patient group. Many studies have address this challenge using different deep learning technologies. This comprehensive review systematically synthesizes research from a wide range of studies to provide an in-depth examination of cutting-edge deep-learning techniques in personalized ECG diagnosis. The review outlines a rigorous methodology for the selection of pertinent scholarly articles and offers a comprehensive overview of deep learning approaches applied to personalized ECG diagnostics. Moreover, the challenges these methods encounter are investigated, along with future research directions, culminating in insights into how the integration of deep learning can transform personalized ECG diagnosis and enhance cardiac care. By emphasizing both the strengths and limitations of current methodologies, this review underscores the immense potential of deep learning to refine and redefine ECG analysis in clinical practice, paving the way for more accurate, efficient, and personalized cardiac diagnostics.

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