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Tieming Liu

Publications and source records attributed to Tieming Liu.

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DR-LabStack: Design and Implementation of a Clinician-Facing Web System for Diabetic Retinopathy Prediction

Pretrained diabetic retinopathy (DR) prediction models differ in their input fields, serialization formats, preprocessing requirements, and output semantics. Making these models accessible through a common clinical interface therefore requires explicit coordination between the user interface and the inference service. We designed and implemented DR-LabStack, a React-Flask web system integrating four externally developed pretrained models: RuleFit, Pruned RuleFit, Elaborative XGBoost, and Two-level Ensemble. A shared form retrieves ordered model features, renders model-specific numerical and categorical controls, and constructs a positional input vector. Backend adapters load heterogeneous artifacts and apply the ensemble's accompanying scaler, while a common JSON response supports binary classification display alongside method and source information. Functional evaluation on September 8, 2026 used copied application files and real model artifacts in a documented isolated environment. All four models loaded and exposed their 14-, 6-, 8-, and 25-field contracts. Sixty-two Flask test-client requests characterized service behavior; 12 limited-vector checks confirmed invocation-path and threshold consistency. Twenty-four browser-component scenarios with mocked transport verified input ordering and result rendering and characterized input-validation behavior. The resulting system demonstrates a reusable interaction and serving workflow for heterogeneous DR models. The contribution is web-system design, integration, and software functionality; clinical effectiveness and clinician usability require separate evaluation.

cs.LG

RiVaT-Fuse: Reliability-Calibrated Variational Tensor Fusion for Multimodal Prediction under Modality Uncertainty

Image-metadata prediction requires fusing heterogeneous evidence whose reliability can vary across samples and latent factors. Existing representation-level fusion methods typically choose an aggregation architecture, such as concatenation, gating, conditional modulation, or attention, without explicitly defining what the fused representation should mean under modality uncertainty. We propose RiVaT-Fuse, a reliability-calibrated variational tensor fusion framework that defines fusion as sample-wise latent-state estimation. Rather than producing a fused vector by direct aggregation, RiVaT-Fuse estimates a consensus latent state through a variational objective that balances image evidence, metadata evidence, structured cross-modal interaction, and stability. The resulting framework replaces scalar modality confidence with matrix-valued trust geometry, decomposes interaction into additive, multiplicative, and relational components, and couples the latent state with conditional robustness and structured multi-task prediction. We provide well-posedness and stability interpretations of the latent solve and instantiate the framework with efficient low-rank-plus-diagonal trust operators. On an image-level image-metadata prediction benchmark, RiVaT-Fuse achieves the strongest overall predictive rank among direct representation-level baselines while improving probability and label stability under perturbation.

cs.LG

Predicting Diabetic Retinopathy Using a Two-Level Ensemble Model

Preprint Note: This is the author preprint version of a paper accepted for presentation at the IISE Annual Conference & Expo 2025. The final version will appear in the official proceedings. Diabetic retinopathy (DR) is a leading cause of blindness in working-age adults, and current diagnostic methods rely on resource-intensive eye exams and specialized equipment. Image-based AI tools have shown limitations in early-stage detection, motivating the need for alternative approaches. We propose a non-image-based, two-level ensemble model for DR prediction using routine laboratory test results. In the first stage, base models (Linear SVC, Random Forest, Gradient Boosting, and XGBoost) are hyperparameter tuned and internally stacked across different configurations to optimize metrics such as accuracy, recall, and precision. In the second stage, predictions are aggregated using Random Forest as a meta-learner. This hierarchical stacking strategy improves generalization, balances performance across multiple metrics, and remains computationally efficient compared to deep learning approaches. The model achieved Accuracy 0.9433, F1 Score 0.9425, Recall 0.9207, Precision 0.9653, ROC-AUC 0.9844, and AUPRC 0.9875, surpassing one-level stacking and FCN baselines. These results highlight the model potential for accurate and interpretable DR risk prediction in clinical settings.

cs.LG

MUSE-Net: Missingness-aware mUlti-branching Self-attention Encoder for Irregular Longitudinal Electronic Health Records

The era of big data has made vast amounts of clinical data readily available, particularly in the form of electronic health records (EHRs), which provides unprecedented opportunities for developing data-driven diagnostic tools to enhance clinical decision making. However, the application of EHRs in data-driven modeling faces challenges such as irregularly spaced multi-variate time series, issues of incompleteness, and data imbalance. Realizing the full data potential of EHRs hinges on the development of advanced analytical models. In this paper, we propose a novel Missingness-aware mUlti-branching Self-Attention Encoder (MUSE-Net) to cope with the challenges in modeling longitudinal EHRs for data-driven disease prediction. The proposed MUSE-Net is composed by four novel modules including: (1) a multi-task Gaussian process (MGP) with missing value masks for data imputation; (2) a multi-branching architecture to address the data imbalance problem; (3) a time-aware self-attention encoder to account for the irregularly spaced time interval in longitudinal EHRs; (4) interpretable multi-head attention mechanism that provides insights into the importance of different time points in disease prediction, allowing clinicians to trace model decisions. We evaluate the proposed MUSE-Net using both synthetic and real-world datasets. Experimental results show that our MUSE-Net outperforms existing methods that are widely used to investigate longitudinal signals.

cs.LG