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Timo Blattner

Publications and source records attributed to Timo Blattner.

2 recordsLinked to original sources

Diversity-guided Search Exploration for Self-driving Cars Test Generation through Frenet Space Encoding

The rise of self-driving cars (SDCs) presents important safety challenges to address in dynamic environments. While field testing is essential, current methods lack diversity in assessing critical SDC scenarios. Prior research introduced simulation-based testing for SDCs, with Frenetic, a test generation approach based on Frenet space encoding, achieving a relatively high percentage of valid tests (approximately 50%) characterized by naturally smooth curves. The "minimal out-of-bound distance" is often taken as a fitness function, which we argue to be a sub-optimal metric. Instead, we show that the likelihood of leading to an out-of-bound condition can be learned by the deep-learning vanilla transformer model. We combine this "inherently learned metric" with a genetic algorithm, which has been shown to produce a high diversity of tests. To validate our approach, we conducted a large-scale empirical evaluation on a dataset comprising over 1,174 simulated test cases created to challenge the SDCs behavior. Our investigation revealed that our approach demonstrates a substantial reduction in generating non-valid test cases, increased diversity, and high accuracy in identifying safety violations during SDC test execution.

cs.SE

Multiscale cortical morphometry reveals pronounced regional and scale-dependent variations across the lifespan

Motivation: Characterising the changes in cortical morphology across the lifespan is fundamental for a range of research and clinical applications. Most studies to date have found a monotonic decrease in commonly used morphometrics, such as cortical thickness and volume, across the entire brain with increasing age. Any regional variations reported are subtle changes in the rate of decrease. However, these descriptions of morphological changes have been limited to a single length scale. Here, we delineate the morphological changes associated with the healthy lifespan in multiscale morphometrics. Methods: We applied multiscale morphometric analysis to structural MRI from subjects aged 6-88 years from NKI (n=833) and CamCAN (n=641). These multiscale morphometrics were obtained at both the cortical hemisphere and lobe level. Results: On the level of whole cortical hemispheres, lifespan trajectories show diverging and even opposing trends at different spatial scales, in contrast to the monotonic decreases of volume and thickness described so far. Importantly, larger scales displayed most dramatic changes across the lifespan (up to 60%). More pronounced lobal differences in lifespan trajectories also became apparent in scales over 0.7mm. In a proof-of-principle application in brain age prediction, we also demonstrate added information contributed by multiscale morphometrics. Conclusion: Our study provides a comprehensive multiscale description of lifespan effects on cortical morphology in an age range from 6-88~years. In future, this can form the foundations for a normative model to compare individuals or cohorts, hence identifying multiscale morphological abnormalities. Our results reveal the complementary information contained in different spatial scales, suggesting that morphometrics should not be considered on a single scale, but as functions of length scale.

q-bio.NC