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Timothy Oladunni

Publications and source records attributed to Timothy Oladunni.

12 recordsLinked to original sources

Property-Specific Recoverability from Contact PPG to Camera rPPG under Heterogeneous Observation Conditions

Camera-derived remote photoplethysmography (rPPG) is commonly validated through endpoint accuracy, but endpoint performance does not establish whether other physiological properties of source contact photoplethysmography (PPG) remain preserved recording by recording. We evaluated property-specific PPG-to-rPPG recoverability on 655 recordings from the Multi-Domain Mobile Video Physiology Dataset using CHROM as a fixed camera-rPPG observation pathway. The pathway reproduced the published CHROM correlation regime, with heart-rate MAE of 15.26 bpm and Pearson correlation of 0.0801. Matched-versus-shuffled validation revealed modest recording-specific autocorrelation correspondence, while spectral and recurrence-rate measures showed little matched discrimination. Maximal Lyapunov exponents showed essentially no recording-specific PPG-to-rPPG correspondence, with correlation of 0.0231 and permutation p-value of 0.5584, despite population-level overlap. Endpoint discrepancy exhibited Fitzpatrick-associated heterogeneity after adjustment for lighting and motion, including a Fitzpatrick VI versus III contrast of 9.32 bpm, while dynamical discrepancy showed no corresponding gradient. Aggregate RGB signal-to-noise ratio did not materially account for the endpoint contrast. In subject-held-out analysis, adding motion and lighting consistently reduced MAE across linear, ridge, and random-forest learners relative to rPPG-HR-only calibration, with reductions up to 13.32 percent. These findings show that recoverability is property-specific: physiological properties differ in recording-specific preservation and dependence on observation conditions, and population-level plausibility does not establish preservation of individual recordings.

eess.SP

CFD-Guided Detection of Concept Drift in Multimodal Physiologic Signals

Cardiovascular AI models can classify clean elec- trocardiogram (ECG) signals, but real wearable signals change because of motion, breathing, posture, sensor contact, and true clinical deterioration. This paper asks when a model should keep its prediction, change it, or flag uncertainty. We propose a physiologic stability framework, called PECS, that compares changes inside the model with measurable changes in the signal. ECG is treated as the main cardiac signal, photoplethysmography (PPG) adds pulse and vascular information, and respiration is used only when ECG and PPG disagree. We test the framework on PTB-XL at pilot and full scales and on synchronized BIDMC and MIMIC waveform cohorts. The PTB-XL pilot and full- scale analyses selected different domain pairs, and the strongest cross-modal pair also changed across BIDMC and MIMIC, showing that adding every available signal is not always the best choice. PECS outperformed the evaluated drift-detection baseline implementations, reaching drift classification accuracy (DCA) of 0.8786 on expanded BIDMC and 0.9560 on MIMIC. The MIMIC results also showed that respiration can help during disagreement cases, but it should be used selectively rather than as an automatic override. Overall, the results support PECS as a candidate monitoring framework for wearable cardiovascular AI while highlighting the need for scale-aware domain selection and interpretable trust routing

eess.SP

Attractor Domain Theory: A Mathematical Framework for Cardiovascular Attractor Analysis with Wearable Photoplethysmography (PPG) Validation

The cardiovascular system evolves along a bounded trajectory in physiological state space that converges to a compact geometric object: the cardiac attractor. A wearable photoplethysmograph (PPG) or electrocardiograph (ECG) observes a one-dimensional projection of this attractor; by Takens' embedding theorem, delay coordinates reconstruct its full geometry. Three decades of nonlinear cardiac dynamics have extracted Lyapunov exponents, recurrence statistics, and sample entropy from reconstructed attractors, yet no principled account exists of which attractor properties capture which cardiovascular quantities, or why, leaving feature selection as a search problem and negative results uninterpretable. We introduce Attractor Domain Theory (ADT), which proves that the reconstructed attractor's information partitions into three mutually non-redundant domains: the Geometry Domain G (delay embedding; native capability: artifact rejection), the Ergodic Domain S (asymptotic statistical invariants; native capability: stability estimation), and the Variational Domain V (finite-time Lyapunov exponent field; native capability: hemodynamic inference). We prove a Domain Sufficiency Theorem (the Parseval analog for attractor information) and establish that three domains are necessary and sufficient. Geometry Domain validation via the SCSI framework across 176,742 PPG segments from four datasets yields AUC = 0.757 [0.686-0.828] and NPV = 0.966 after correcting three systematic evaluation artifacts (+0.179 net inflation). Ablation confirms C_NL as the dominant Geometry Domain component (Delta AUC = -0.413) and intra-domain redundancy across five components.

cs.AI

Attractor-Vascular Coupling Theory: Formal Grounding and Empirical Validation for AAMI-Standard Cuffless Blood Pressure Estimation from Smartphone Photoplethysmography

This work proposes Attractor-Vascular Coupling Theory (AVCT), a mathematical framework showing that cardiac attractor geometry encodes blood pressure (BP) information sufficient for AAMI-standard estimation, and validates the theory through a calibrated cuffless BP model using photoplethysmography (PPG). AVCT is grounded in Cardiac Stability Theory and operationalized using Takens delay embedding and attractor morphology extraction. Two theorems, one proposition, and one corollary formally justify the use of PPG attractor features for BP estimation and predict the feature-importance hierarchy. A LightGBM model trained on pulse transit time (PTT) and Cardiac Stability Index (CSI) attractor features under single-point calibration was evaluated using strict leave-one-subject-out cross-validation (LOSO-CV) on 46 subjects from BIDMC ICU (n = 9) and VitalDB surgical data (n = 37), comprising 29,684 windows. The model achieved systolic BP (SBP) mean absolute error (MAE) of 2.05 mmHg and diastolic BP (DBP) MAE of 1.67 mmHg, with correlations r = 0.990 and r = 0.991, satisfying the AAMI/IEEE SP10 requirement of MAE below 5 mmHg. Median per-subject MAE was 1.87/1.54 mmHg, and 70%/76% of subjects individually satisfied AAMI criteria. A PPG-only ablation using nine smartphone attractor features matched the ECG+PPG model within 0.05 mmHg, demonstrating that clinical-grade BP tracking is achievable using only a smartphone camera while surpassing prior generalized LOSO-CV results using fewer sensors. All four AVCT predictions were quantitatively confirmed, with 91.5% error reduction from uncalibrated to calibrated estimation (epsilon_cal = 0.915). Unlike post-hoc explainable AI methods, AVCT predicts features satisfying the architectural faithfulness criterion of the Explainable-AI Trustworthiness (EAT) framework and grounding BP estimation in nonlinear dynamical systems theory.

physics.med-ph

Cardiac Stability Theory: An Axiomatically Grounded Framework for Continuous Cardiac Health Monitoring via Smartphone Photoplethysmography

We present Cardiac Stability Theory (CST), an axiomatically grounded framework formally defining cardiovascular health as a stability margin around a cardiac dynamical attractor. From four axioms we derive the Cardiac Stability Index (CSI), a composite scalar in [0,1] integrating the largest Lyapunov exponent, recurrence determinism, and signal entropy via time-delay embedding. The ECG-based model (CSISurrogateV2, CNN-Transformer) achieves $R^2=0.8788$, MAE$=0.0234$ on PTB-XL (21,799 recordings). We extend CSI to smartphone PPG via Complementary Domain Transfer (CDT): CSISurrogateV2 generates pseudo-labels for the BUT PPG dataset (48 recordings, 12 subjects), training TinyCSINet (122,849 parameters), achieving MAE$=0.0557$, $ρ=0.660$ on the held-out test set ($n=1065$ windows) at ${<}30$ ms mobile latency. CDT is validated on BIDMC, Welltory, and RWS-PPG. Paired validation on 5,035 BIDMC windows yields $r=0.454$ ($ρ=0.485$, $p<10^{-295}$), confirming correlated cardiac stability across modalities. CSI is negatively correlated with age (slope $= -0.000225$ CSI/year, PTB-XL), discriminates atrial fibrillation from normal sinus rhythm (AUROC$=0.89$), and is robust under Perturbation Invariance Training (max AUC drop 1.65\%). We derive HeartSpan, a longitudinal stability metric relative to population age norms, enabling continuous non-invasive cardiac monitoring from commodity smartphones for longevity tracking and cardiac risk stratification.

cs.LG

A Nonlinear Complexity Index for Wearable PPG Cardiovascular Stability: Multiscale Validation, Systematic Evaluation Correction, and Bayesian Parameter Optimization

Cardiovascular stability estimation from wearable photoplethysmography (PPG) requires a principled nonlinear framework, yet major gaps persist in heuristic parameter selection and evaluation protocols that inflate reported performance. We introduce a Stability-Constrained Cardiovascular Stability Index (SCSI) grounded in Cardiac Stability Theory and validate it across 176,742 segments from four heterogeneous PPG datasets at three temporal scales. Cross-dataset analysis demonstrates a large Kruskal-Wallis effect size (eta2 = 0.351, p < 0.001), strong cross-scale consistency (kappa > 0.97), and significant correlation with respiratory rate across 53 ICU records (Spearman r = 0.346, p = 0.011). We identify three evaluation artifacts that inflate heuristic AUC from a true baseline of 0.573 to 0.752: segment-level cross-validation leakage, test-set normalization leakage, and pooled-AUC overweighting that conceals per-patient failure. Correcting these artifacts and applying Bayesian optimization over 15 joint parameters yields SCSI with cross-validation AUC of 0.720. On 18 held-out records, SCSI achieves pooled AUC of 0.757 (95% CI: 0.686-0.828) and negative predictive value of 0.966 for tachypnea screening, while per-record AUC of 0.497 +/- 0.207 is disclosed for transparency. External validation on 42 elective-surgery records yields AUC of 0.621, confirming cross-population generalization. Ablation analysis identifies the nonlinear complexity module as the dominant component. A sparse three-component architecture is proposed as the minimal deployable configuration. The corrected protocol provides a reproducible benchmark for future wearable cardiovascular stability indices.

eess.SP

Complementarity-Preserving Generative Theory for Multimodal ECG Synthesis: A Quantum-Inspired Approach

Multimodal deep learning has substantially improved electrocardiogram (ECG) classification by jointly leveraging time, frequency, and time-frequency representations. However, existing generative models typically synthesize these modalities independently, resulting in synthetic ECG data that are visually plausible yet physiologically inconsistent across domains. This work establishes a Complementarity-Preserving Generative Theory (CPGT), which posits that physiologically valid multimodal signal generation requires explicit preservation of cross-domain complementarity rather than loosely coupled modality synthesis. We instantiate CPGT through Q-CFD-GAN, a quantum-inspired generative framework that models multimodal ECG structure within a complex-valued latent space and enforces complementarity-aware constraints regulating mutual information, redundancy, and morphological coherence. Experimental evaluation demonstrates that Q-CFD-GAN reduces latent embedding variance by 82%, decreases classifier-based plausibility error by 26.6%, and restores tri-domain complementarity from 0.56 to 0.91, while achieving the lowest observed morphology deviation (3.8%). These findings show that preserving multimodal information geometry, rather than optimizing modality-specific fidelity alone, is essential for generating synthetic ECG signals that remain physiologically meaningful and suitable for downstream clinical machine-learning applications.

eess.SP

When Should a Model Change Its Mind? An Energy-Based Theory and Regularizer for Concept Drift in Electrocardiogram (ECG) Signals

Models operating on dynamic physiologic signals must distinguish benign, label-preserving variability from true concept change. Existing concept-drift frameworks are largely distributional and provide no principled guidance on how much a model's internal representation may move when the underlying signal undergoes physiologically plausible fluctuations in energy. As a result, deep models often misinterpret harmless changes in amplitude, rate, or morphology as concept drift, yielding unstable predictions, particularly in multimodal fusion settings. This study introduces Physiologic Energy Conservation Theory (PECT), an energy-based framework for concept stability in dynamic signals. PECT posits that under virtual drift, normalized latent displacement should scale proportionally with normalized signal energy change, while persistent violations of this proportionality indicate real concept drift. We operationalize this principle through Energy-Constrained Representation Learning (ECRL), a lightweight regularizer that penalizes energy-inconsistent latent movement without modifying encoder architectures or adding inference-time cost. Although PECT is formulated for dynamic signals in general, we instantiate and evaluate it on multimodal ECG across seven unimodal and hybrid models. Experiments show that in the strongest trimodal hybrid (1D+2D+Transformer), clean accuracy is largely preserved (96.0% to 94.1%), while perturbed accuracy improves substantially (72.6% to 85.5%) and fused representation drift decreases by over 45%. Similar trends are observed across all architectures, providing empirical evidence that PECT functions as an energy-drift law governing concept stability in continuous physiologic signals.

cs.LG

Explainable Deep Neural Network for Multimodal ECG Signals: Intermediate vs Late Fusion

The limitations of unimodal deep learning models, particularly their tendency to overfit and limited generalizability, have renewed interest in multimodal fusion strategies. Multimodal deep neural networks (MDNN) have the capability of integrating diverse data domains and offer a promising solution for robust and accurate predictions. However, the optimal fusion strategy, intermediate fusion (feature-level) versus late fusion (decision-level) remains insufficiently examined, especially in high-stakes clinical contexts such as ECG-based cardiovascular disease (CVD) classification. This study investigates the comparative effectiveness of intermediate and late fusion strategies using ECG signals across three domains: time, frequency, and time-frequency. A series of experiments were conducted to identify the highest-performing fusion architecture. Results demonstrate that intermediate fusion consistently outperformed late fusion, achieving a peak accuracy of 97 percent, with Cohen's d > 0.8 relative to standalone models and d = 0.40 compared to late fusion. Interpretability analyses using saliency maps reveal that both models align with the discretized ECG signals. Statistical dependency between the discretized ECG signals and corresponding saliency maps for each class was confirmed using Mutual Information (MI). The proposed ECG domain-based multimodal model offers superior predictive capability and enhanced explainability, crucial attributes in medical AI applications, surpassing state-of-the-art models.

eess.SP

Rethinking Multimodality: Optimizing Multimodal Deep Learning for Biomedical Signal Classification

This study proposes a novel perspective on multimodal deep learning for biomedical signal classification, systematically analyzing how complementary feature domains impact model performance. While fusing multiple domains often presumes enhanced accuracy, this work demonstrates that adding modalities can yield diminishing returns, as not all fusions are inherently advantageous. To validate this, five deep learning models were designed, developed, and rigorously evaluated: three unimodal (1D-CNN for time, 2D-CNN for time-frequency, and 1D-CNN-Transformer for frequency) and two multimodal (Hybrid 1, which fuses 1D-CNN and 2D-CNN; Hybrid 2, which combines 1D-CNN, 2D-CNN, and a Transformer). For ECG classification, bootstrapping and Bayesian inference revealed that Hybrid 1 consistently outperformed the 2D-CNN baseline across all metrics (p-values < 0.05, Bayesian probabilities > 0.90), confirming the synergistic complementarity of the time and time-frequency domains. Conversely, Hybrid 2's inclusion of the frequency domain offered no further improvement and sometimes a marginal decline, indicating representational redundancy; a phenomenon further substantiated by a targeted ablation study. This research redefines a fundamental principle of multimodal design in biomedical signal analysis. We demonstrate that optimal domain fusion isn't about the number of modalities, but the quality of their inherent complementarity. This paradigm-shifting concept moves beyond purely heuristic feature selection. Our novel theoretical contribution, "Complementary Feature Domains in Multimodal ECG Deep Learning," presents a mathematically quantifiable framework for identifying ideal domain combinations, demonstrating that optimal multimodal performance arises from the intrinsic information-theoretic complementarity among fused domains.

cs.LG

Advancements in Generative AI: A Comprehensive Review of GANs, GPT, Autoencoders, Diffusion Model, and Transformers

The launch of ChatGPT has garnered global attention, marking a significant milestone in the field of Generative Artificial Intelligence. While Generative AI has been in effect for the past decade, the introduction of ChatGPT has ignited a new wave of research and innovation in the AI domain. This surge in interest has led to the development and release of numerous cutting-edge tools, such as Bard, Stable Diffusion, DALL-E, Make-A-Video, Runway ML, and Jukebox, among others. These tools exhibit remarkable capabilities, encompassing tasks ranging from text generation and music composition, image creation, video production, code generation, and even scientific work. They are built upon various state-of-the-art models, including Stable Diffusion, transformer models like GPT-3 (recent GPT-4), variational autoencoders, and generative adversarial networks. This advancement in Generative AI presents a wealth of exciting opportunities and, simultaneously, unprecedented challenges. Throughout this paper, we have explored these state-of-the-art models, the diverse array of tasks they can accomplish, the challenges they pose, and the promising future of Generative Artificial Intelligence.

cs.LG

Wind Speed Prediction and Visualization Using Long Short-Term Memory Networks (LSTM)

Climate change is one of the most concerning issues of this century. Emission from electric power generation is a crucial factor that drives the concern to the next level. Renewable energy sources are widespread and available globally, however, one of the major challenges is to understand their characteristics in a more informative way. This paper proposes the prediction of wind speed that simplifies wind farm planning and feasibility study. Twelve artificial intelligence algorithms were used for wind speed prediction from collected meteorological parameters. The model performances were compared to determine the wind speed prediction accuracy. The results show a deep learning approach, long short-term memory (LSTM) outperforms other models with the highest accuracy of 97.8%.

cs.LG