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Timothy Ossowski

Publications and source records attributed to Timothy Ossowski.

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HealthAgentBench: A Unified Benchmark Suite of Realistic Agentic Healthcare Environments for Challenging Frontier AI Agents

As AI agents become increasingly capable of complex, long-horizon reasoning, rigorous and holistic evaluation is essential for measuring progress toward real-world healthcare applications. We introduce HealthAgentBench, a suite of 54 agentic healthcare tasks across 7 categories each with its unique environment. The benchmark suite spans diverse workflows throughout the patient journey and a broad range of modalities. Each task is designed to replicate an end-to-end clinical workflow: given minimal instructions, an agent must explore raw healthcare data, operate within a complex environment, and execute multi-step solutions that go beyond naive prompting. A final task success rate is reported to provide a single, interpretable metric for HealthAgentBench overall performance for each agent. Evaluating frontier agents on HealthAgentBench, we find that overall task success rate remains low, underscoring the difficulty of the suite. The strongest and the most cost effective agent, Codex GPT-5.5, achieves only approximately 42% success rate. Beyond aggregate performance, HealthAgentBench reveals nuanced strengths and weaknesses across task categories. Frontier agents show promise in automatically developing research modeling pipelines over EHR data, but medical imaging remains especially challenging, particularly for Claude Code models, while Codex GPT-5.5 shows emerging capability. Tasks that combine large search spaces with compositional reasoning requirements remain difficult for all current agents. Together, these results suggest that HealthAgentBench provides a challenging and realistic benchmark with substantial room for future progress. We release our benchmark at https://github.com/microsoft/HealthAgentBench.

cs.AI

CodeClinic: Evaluating Automation of Coding Skills for Clinical Reasoning Agents

Clinical reasoning agents based on large language models (LLMs) aim to automate tasks such as intensive care unit (ICU) monitoring and patient state tracking from electronic health records (EHRs). Existing systems typically rely on manually curated clinical tools or skills for concepts such as sepsis detection and organ failure assessment. However, maintaining these tool libraries requires substantial expert effort, while zero-shot querying or code generation often produces inefficient and unreliable reasoning chains, especially under institution-specific clinical policies. We introduce CodeClinic, a benchmark built on MIMIC-IV for evaluating whether LLM agents can synthesize and compose reusable clinical skills instead of relying on fixed toolboxes. The benchmark contains two complementary tasks: longitudinal ICU surveillance and compositional information seeking. The longitudinal setting simulates monitoring patient trajectories with structured decisions every four hours across 25 findings and eight clinical families, while the compositional setting spans 63k instances across 259 tasks in nine domains and is stratified by compositional dependency depth to evaluate increasingly complex multi-step reasoning. We further propose an offline autoformalization pipeline that converts natural-language clinical guidelines into reusable and verified Python skill libraries through iterative LLM refinement. Compared with zero-shot code generation, the resulting libraries improve consistency while reducing per-query token usage by up to 40%.

cs.AI

Scaling medical imaging report generation with multimodal reinforcement learning

Frontier models have demonstrated remarkable capabilities in understanding and reasoning with natural-language text, but they still exhibit major competency gaps in multimodal understanding and reasoning especially in high-value verticals such as biomedicine. Medical imaging report generation is a prominent example. Supervised fine-tuning can substantially improve performance, but they are prone to overfitting to superficial boilerplate patterns. In this paper, we introduce Universal Report Generation (UniRG) as a general framework for medical imaging report generation. By leveraging reinforcement learning as a unifying mechanism to directly optimize for evaluation metrics designed for end applications, UniRG can significantly improve upon supervised fine-tuning and attain durable generalization across diverse institutions and clinical practices. We trained UniRG-CXR on publicly available chest X-ray (CXR) data and conducted a thorough evaluation in CXR report generation with rigorous evaluation scenarios. On the authoritative ReXrank benchmark, UniRG-CXR sets new overall SOTA, outperforming prior state of the art by a wide margin. We release our model at https://huggingface.co/microsoft/UniRG-CXR.

cs.CV

RiskCueBench: Benchmarking Anticipatory Reasoning from Early Risk Cues in Video-Language Models

With the rapid growth of video centered social media, the ability to anticipate risky events from visual data is a promising direction for ensuring public safety and preventing real world accidents. Prior work has extensively studied supervised video risk assessment across domains such as driving, protests, and natural disasters. However, many existing datasets provide models with access to the full video sequence, including the accident itself, which substantially reduces the difficulty of the task. To better reflect real world conditions, we introduce a new video understanding benchmark RiskCueBench in which videos are carefully annotated to identify a risk signal clip, defined as the earliest moment that indicates a potential safety concern. Experimental results reveal a significant gap in current systems ability to interpret evolving situations and anticipate future risky events from early visual signals, highlighting important challenges for deploying video risk prediction models in practice.

cs.CV

OctoMed: Data Recipes for State-of-the-Art Multimodal Medical Reasoning

High-quality and carefully curated data is a cornerstone of training medical large language models, as it directly impacts both generalization and robustness to unseen clinical tasks. We investigate strategies for training and data curation to develop a robust multimodal reasoning model in the medical domain. Our work focuses on supervised fine-tuning (SFT) and explores data recipes that leverage structured reasoning traces. Using our proposed data recipe, we scale experiments to a dataset of over 8 million examples and 6.8 billion response tokens, achieving state-of-the-art performance among open-source models across diverse out-of-distribution medical benchmark tasks. Our results further indicate that curating a high-quality, diverse training dataset with varying structured reasoning trace lengths enables the fine-tuned model to self-calibrate its reasoning trajectory lengths based on the downstream task, without explicit supervision. We present key insights, describe the data curation strategy, and outline next steps toward developing robust medical vision-language reasoning system.

cs.AI

X-Reasoner: Towards Generalizable Reasoning Across Modalities and Domains

Recent proprietary models (e.g., o3) have begun to demonstrate strong multimodal reasoning capabilities. Yet, most existing open-source research concentrates on training text-only reasoning models, with evaluations limited to mainly mathematical and general-domain tasks. Therefore, it remains unclear how to effectively extend reasoning capabilities beyond text input and general domains. This paper explores a fundamental research question: Is reasoning generalizable across modalities and domains? Our findings support an affirmative answer: General-domain text-based post-training can enable such strong generalizable reasoning. Leveraging this finding, we introduce X-Reasoner, a vision-language model post-trained solely on general-domain text for generalizable reasoning, using a two-stage approach: an initial supervised fine-tuning phase with distilled long chain-of-thoughts, followed by reinforcement learning with verifiable rewards. Experiments show that X-Reasoner successfully transfers reasoning capabilities to both multimodal and out-of-domain settings, outperforming existing state-of-the-art models trained with in-domain and multimodal data across various general and medical benchmarks (Figure 1). Additionally, we find that X-Reasoner's performance in specialized domains can be further enhanced through continued training on domain-specific text-only data. Building upon this, we introduce X-Reasoner-Med, a medical-specialized variant that achieves new state of the art on numerous text-only and multimodal medical benchmarks.

cs.AI

COMMA: A Communicative Multimodal Multi-Agent Benchmark

The rapid advances of multimodal agents built on large foundation models have largely overlooked their potential for language-based communication between agents in collaborative tasks. This oversight presents a critical gap in understanding their effectiveness in real-world deployments, particularly when communicating with humans. Existing agentic benchmarks fail to address key aspects of inter-agent communication and collaboration, particularly in scenarios where agents have unequal access to information and must work together to achieve tasks beyond the scope of individual capabilities. To fill this gap, we introduce COMMA: a novel puzzle benchmark designed to evaluate the collaborative performance of multimodal multi-agent systems through language communication. Our benchmark features a variety of multimodal puzzles, providing a comprehensive evaluation across four key categories of agentic capability in a communicative collaboration setting. Our findings reveal surprising weaknesses in state-of-the-art models, including strong proprietary models like GPT-4o and reasoning models like o4-mini. Many chain of thought reasoning models such as R1-Onevision and LLaVA-CoT struggle to outperform even a random baseline in agent-agent collaboration, indicating a potential growth area in their communication abilities.

cs.AI

OLIVE: Object Level In-Context Visual Embeddings

Recent generalist vision-language models (VLMs) have demonstrated impressive reasoning capabilities across diverse multimodal tasks. However, these models still struggle with fine-grained object-level understanding and grounding. In terms of modeling, existing VLMs implicitly align text tokens with image patch tokens, which is ineffective for embedding alignment at the same granularity and inevitably introduces noisy spurious background features. Additionally, these models struggle when generalizing to unseen visual concepts and may not be reliable for domain-specific tasks without further fine-tuning. To address these limitations, we propose a novel method to prompt large language models with in-context visual object vectors, thereby enabling controllable object-level reasoning. This eliminates the necessity of fusing a lengthy array of image patch features and significantly speeds up training. Furthermore, we propose region-level retrieval using our object representations, facilitating rapid adaptation to new objects without additional training. Our experiments reveal that our method achieves competitive referring object classification and captioning performance, while also offering zero-shot generalization and robustness to visually challenging contexts.

cs.CV

How does Multi-Task Training Affect Transformer In-Context Capabilities? Investigations with Function Classes

Large language models (LLM) have recently shown the extraordinary ability to perform unseen tasks based on few-shot examples provided as text, also known as in-context learning (ICL). While recent works have attempted to understand the mechanisms driving ICL, few have explored training strategies that incentivize these models to generalize to multiple tasks. Multi-task learning (MTL) for generalist models is a promising direction that offers transfer learning potential, enabling large parameterized models to be trained from simpler, related tasks. In this work, we investigate the combination of MTL with ICL to build models that efficiently learn tasks while being robust to out-of-distribution examples. We propose several effective curriculum learning strategies that allow ICL models to achieve higher data efficiency and more stable convergence. Our experiments reveal that ICL models can effectively learn difficult tasks by training on progressively harder tasks while mixing in prior tasks, denoted as mixed curriculum in this work. Our code and models are available at https://github.com/harmonbhasin/curriculum_learning_icl .

cs.CL

Prompting Large Vision-Language Models for Compositional Reasoning

Vision-language models such as CLIP have shown impressive capabilities in encoding texts and images into aligned embeddings, enabling the retrieval of multimodal data in a shared embedding space. However, these embedding-based models still face challenges in effectively matching images and texts with similar visio-linguistic compositionality, as evidenced by their performance on the recent Winoground dataset. In this paper, we argue that this limitation stems from two factors: the use of single vector representations for complex multimodal data, and the absence of step-by-step reasoning in these embedding-based methods. To address this issue, we make an exploratory step using a novel generative method that prompts large vision-language models (e.g., GPT-4) to depict images and perform compositional reasoning. Our method outperforms other embedding-based methods on the Winoground dataset, and obtains further improvement of up to 10% accuracy when enhanced with the optimal description.

cs.CV

Multimodal Prompt Retrieval for Generative Visual Question Answering

Recent years have witnessed impressive results of pre-trained vision-language models on knowledge-intensive tasks such as visual question answering (VQA). Despite the recent advances in VQA, existing methods mainly adopt a discriminative formulation that predicts answers within a pre-defined label set, leading to easy overfitting on low-resource domains with limited labeled data (e.g., medicine) and poor generalization under domain shift to another dataset. To tackle this limitation, we propose a novel generative model enhanced by multimodal prompt retrieval (MPR) that integrates retrieved prompts and multimodal features to generate answers in free text. Our generative model enables rapid zero-shot dataset adaptation to unseen data distributions and open-set answer labels across datasets. Our experiments on medical VQA tasks show that MPR outperforms its non-retrieval counterpart by up to 30% accuracy points in a few-shot domain adaptation setting.

cs.CV

Utilizing Language-Image Pretraining for Efficient and Robust Bilingual Word Alignment

Word translation without parallel corpora has become feasible, rivaling the performance of supervised methods. Recent findings have shown that the accuracy and robustness of unsupervised word translation (UWT) can be improved by making use of visual observations, which are universal representations across languages. In this work, we investigate the potential of using not only visual observations but also pretrained language-image models for enabling a more efficient and robust UWT. Specifically, we develop a novel UWT method dubbed Word Alignment using Language-Image Pretraining (WALIP), which leverages visual observations via the shared embedding space of images and texts provided by CLIP models (Radford et al., 2021). WALIP has a two-step procedure. First, we retrieve word pairs with high confidences of similarity, computed using our proposed image-based fingerprints, which define the initial pivot for the word alignment. Second, we apply our robust Procrustes algorithm to estimate the linear mapping between two embedding spaces, which iteratively corrects and refines the estimated alignment. Our extensive experiments show that WALIP improves upon the state-of-the-art performance of bilingual word alignment for a few language pairs across different word embeddings and displays great robustness to the dissimilarity of language pairs or training corpora for two word embeddings.

cs.CL