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Tobias Wistuba

Publications and source records attributed to Tobias Wistuba.

3 recordsLinked to original sources

Physiological and Behavioral Modeling of Stress and Cognitive Load in Web-Based Question Answering

Time pressure and question difficulty can trigger stress and cognitive overload in web-based surveys, compromising data quality and user experience. Most stress detection methods are based on low-resolution self-reports, which are poorly suited for capturing fast, moment-to-moment changes during short online tasks. Addressing this gap, we conducted a 2x2 within-subjects study (N = 29), manipulating question difficulty and time pressure in a web-based multiple-choice task. Participants completed general knowledge and cognitive questions while we collected multimodal data: mouse dynamics, eye tracking, electrocardiogram, and electrodermal activity. Using condition-based and self-reported labels, we used statistical and machine learning models to model stress and question difficulty. Our results show distinct physiological and behavioral patterns within very short timeframes. This work demonstrates the feasibility of rapidly detecting cognitive-affective states in digital environments, paving the way for more adaptive, ethical, and user-aware survey interfaces.

cs.HC↗

Estimating the course of the COVID-19 pandemic in Germany via spline-based hierarchical modelling of death counts

The effective reproduction number is a key figure to monitor the course of the COVID-19 pandemic. In this study we consider a retrospective modelling approach for estimating the effective reproduction number based on death counts during the first year of the pandemic in Germany. The proposed Bayesian hierarchical model incorporates splines to estimate reproduction numbers flexibly over time while adjusting for varying effective infection fatality rates. The approach also provides estimates of dark figures regarding undetected infections over time. Results for Germany illustrate that estimated reproduction numbers based on death counts are often similar to classical estimates based on confirmed cases. However, considering death counts proves to be more robust against shifts in testing policies: during the second wave of infections, classical estimation of the reproduction number suggests a flattening/ decreasing trend of infections following the "lockdown light" in November 2020, while our results indicate that true numbers of infections continued to rise until the "second lockdown" in December 2020. This observation is associated with more stringent testing criteria introduced concurrently with the "lockdown light", which is reflected in subsequently increasing dark figures of infections estimated by our model. These findings illustrate that the retrospective viewpoint can provide additional insights regarding the course of the pandemic. In light of progressive vaccinations, shifting the focus from modelling confirmed cases to reported deaths with the possibility to incorporate effective infection fatality rates might be of increasing relevance for the future surveillance of the pandemic.

q-bio.PE↗

Estimating effective infection fatality rates during the course of the COVID-19 pandemic in Germany

The infection fatality rate (IFR) of the Coronavirus Disease 2019 (COVID-19) is one of the most discussed figures in the context of this pandemic. Using German COVID-19 surveillance data and age-group specific IFR estimates from multiple international studies, this work investigates time-dependent variations in effective IFR over the course of the pandemic. Three different methods for estimating (effective) IFRs are presented: (a) population-averaged IFRs based on the assumption that the infection risk is independent of age and time, (b) effective IFRs based on the assumption that the age distribution of confirmed cases approximately reflects the age distribution of infected individuals, and (c) effective IFRs accounting for age- and time-dependent dark figures of infections. Results show that effective IFRs in Germany are estimated to vary over time, as the age distributions of confirmed cases and estimated infections are changing during the course of the pandemic. In particular during the first and second waves of infections in spring and autumn/winter 2020, there has been a pronounced shift in the age distribution of confirmed cases towards older age groups, resulting in larger effective IFR estimates. The temporary increase in effective IFR during the first wave is estimated to be smaller but still remains when adjusting for age- and time-dependent dark figures. A comparison of effective IFRs with observed CFRs indicates that a substantial fraction of the time-dependent variability in observed mortality can be explained by changes in the age distribution of infections. Furthermore, a vanishing gap between effective IFRs and observed CFRs is apparent after the first infection wave, while a moderately increasing gap can be observed during the second wave. Further research is warranted to obtain timely age-stratified IFR estimates.

q-bio.PE↗