arXiv subjects

Tom Baden

Publications and source records attributed to Tom Baden.

3 recordsLinked to original sources

arXiv2025

Categorical Distributions are Effective Neural Network Outputs for Event Prediction

We demonstrate the effectiveness of the categorical distribution as a neural network output for next event prediction. This is done for both discrete-time and continuous-time event sequences. To model continuous-time processes, the categorical distribution is interpreted as a piecewise-constant density function and is shown to be competitive across a range of datasets. We then argue for the importance of studying discrete-time processes by introducing a neuronal spike prediction task motivated by retinal prosthetics, where discretization of event times is consequent on the task description. Separately, we show evidence that commonly used datasets favour smaller models. Finally, we introduce new synthetic datasets for testing larger models, as well as synthetic datasets with discrete event times.

cs.LG↗

arXiv2023

Spike distance function as a learning objective for spike prediction

Approaches to predicting neuronal spike responses commonly use a Poisson learning objective. This objective quantizes responses into spike counts within a fixed summation interval, typically on the order of 10 to 100 milliseconds in duration; however, neuronal responses are often time accurate down to a few milliseconds, and Poisson models struggle to precisely model them at these timescales. We propose the concept of a spike distance function that maps points in time to the temporal distance to the nearest spike. We show that neural networks can be trained to approximate spike distance functions, and we present an efficient algorithm for inferring spike trains from the outputs of these models. Using recordings of chicken and frog retinal ganglion cells responding to visual stimuli, we compare the performance of our approach to that of Poisson models trained with various summation intervals. We show that our approach outperforms the use of Poisson models at spike train inference.

q-bio.NC↗

arXiv2015

Supervised learning sets benchmark for robust spike detection from calcium imaging signals

A fundamental challenge in calcium imaging has been to infer the timing of action potentials from the measured noisy calcium fluorescence traces. We systematically evaluate a range of spike inference algorithms on a large benchmark dataset recorded from varying neural tissue (V1 and retina) using different calcium indicators (OGB-1 and GCamp6). We show that a new algorithm based on supervised learning in flexible probabilistic models outperforms all previously published techniques, setting a new standard for spike inference from calcium signals. Importantly, it performs better than other algorithms even on datasets not seen during training. Future data acquired in new experimental conditions can easily be used to further improve its spike prediction accuracy and generalization performance. Finally, we show that comparing algorithms on artificial data is not informative about performance on real population imaging data, suggesting that a benchmark dataset may greatly facilitate future algorithmic developments.

stat.ML↗