SearcharxivSearch

arXiv subjects

Tom Purdy

Publications and source records attributed to Tom Purdy.

2 recordsLinked to original sources

Variational Joint Magnetometry and Gradiometry on Dipolar Spin Chains

Estimating a uniform magnetic field B0 and its spatial gradient g on a dipolar-coupled spin chain calls for a multiparameter figure of merit. The GHZ state, optimal for single-parameter Heisenberg-limited sensing, has a rank-one quantum Fisher information matrix with det(Q^GHZ) = 0 at every chain length N, ruling it out for the two-parameter problem. We present a variational framework that takes det(F) as the objective and a hardware-motivated layered dipolar circuit as the ansatz. Both encoding generators are diagonal in the computational basis, which reduces the search for the quantum Fisher information benchmark to a probability-simplex optimization and yields a tractable best-found benchmark det(Q*) against which variational performance is compared. The same diagonal structure makes the classical Fisher information depend only on basis-state probabilities under any single-qubit decoder, so encoder and decoder parameters are co-trained with CMA-ES in a single run. Decoder optimization past fixed Ramsey adds at most a few percentage points across the grid, in contrast to the persistent decoder gains seen in our prior single-parameter work. Variational probes at L = 3 reach 0.92 of the best-found benchmark at N = 5, a 4.2x SQL advantage in det(F), and concentrate on a four-string motif of the two GHZ extrema and two half-chain-flip strings whose structure follows from the Dicke-sector decomposition of the two generators.

quant-ph

Four Generations of Quantum Biomedical Sensors

Quantum sensing technologies offer transformative potential for ultra-sensitive biomedical sensing, yet their clinical translation remains constrained by classical noise limits and a reliance on macroscopic ensembles. We propose a unifying generational framework to organize the evolving landscape of quantum biosensors based on their utilization of quantum resources. First-generation devices utilize discrete energy levels for signal transduction but follow classical scaling laws. Second-generation sensors exploit quantum coherence, extending precision with the coherence time up to the standard quantum limit, while third-generation architectures employ entanglement and spin squeezing to approach Heisenberg-limited precision. We define an emerging fourth generation characterized by the end-to-end integration of quantum sensing with quantum learning and variational circuits, enabling adaptive inference directly within the quantum domain. By introducing a bandwidth-matching analysis pairing the neural signal hierarchy with platform response bandwidths, classifying deployed clinical devices by precision-scaling class and sensor-tissue proximity, and outlining a staged physical-milestone roadmap toward learning-integrated sensor networks, we identify key technological bottlenecks and chart the transition from measuring physical observables to extracting structured biological information with quantum-enhanced intelligence.

quant-ph