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Udaya B. Kogalur

Publications and source records attributed to Udaya B. Kogalur.

3 recordsLinked to original sources

Random Hazard Forests

Clinical data sources such as electronic health records and wearable sensors record patient status repeatedly over follow-up, often at irregular times and on different schedules for different measurements. These data create opportunities for continuously updated, individualized risk prediction. Existing approaches, however, often simplify the temporal structure for model fitting. We introduce Random Hazard Forests (RHF), a survival tree ensemble that estimates how a patient's hazard changes in continuous time as new measurements become available. The method formulates the estimation problem directly through a nonparametric hazard likelihood for predictable covariate processes. An efficient working model guides tree construction, after which flexible time-varying hazards are estimated for each terminal node. Given any predictable covariate path, each tree follows the path through its terminal nodes over time and assembles the corresponding node-level hazards into a trajectory. Averaging these trajectories across trees yields the pathwise hazard estimate. Because routing at each time uses only the covariate state available immediately beforehand, the construction accommodates internal longitudinal covariates without lookahead. Simulations and an intensive care application show that the forest accurately estimates changing risk under irregular and asynchronous covariate updates.

stat.ML↗

Consistency of Random Survival Forests

We prove uniform consistency of Random Survival Forests (RSF), a newly introduced forest ensemble learner for analysis of right-censored survival data. Consistency is proven under general splitting rules, bootstrapping, and random selection of variables--that is, under true implementation of the methodology. A key assumption made is that all variables are factors. Although this assumes that the feature space has finite cardinality, in practice the space can be a extremely large--indeed, current computational procedures do not properly deal with this setting. An indirect consequence of this work is the introduction of new computational methodology for dealing with factors with unlimited number of labels.

math.ST↗

Random survival forests

We introduce random survival forests, a random forests method for the analysis of right-censored survival data. New survival splitting rules for growing survival trees are introduced, as is a new missing data algorithm for imputing missing data. A conservation-of-events principle for survival forests is introduced and used to define ensemble mortality, a simple interpretable measure of mortality that can be used as a predicted outcome. Several illustrative examples are given, including a case study of the prognostic implications of body mass for individuals with coronary artery disease. Computations for all examples were implemented using the freely available R-software package, randomSurvivalForest.

stat.AP↗